Published in Biotechnol Bioeng on February 01, 2008
Computational design of Candida boidinii xylose reductase for altered cofactor specificity. Protein Sci (2009) 1.02
Controlled oxidation of remote sp3 C-H bonds in artemisinin via P450 catalysts with fine-tuned regio- and stereoselectivity. J Am Chem Soc (2012) 0.99
Enzymatic C(sp(3))-H Amination: P450-Catalyzed Conversion of Carbonazidates into Oxazolidinones. ACS Catal (2015) 0.97
Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis. Future Med Chem (2011) 0.90
Predicting protein thermostability changes from sequence upon multiple mutations. Bioinformatics (2008) 0.89
Discovery of potent parthenolide-based antileukemic agents enabled by late-stage P450-mediated C-H functionalization. ACS Chem Biol (2013) 0.86
Enhancing the efficiency and regioselectivity of P450 oxidation catalysts by unnatural amino acid mutagenesis. Chembiochem (2014) 0.84
Directed evolution of bright mutants of an oxygen-independent flavin-binding fluorescent protein from Pseudomonas putida. J Biol Eng (2012) 0.82
Site Saturation Mutagenesis Applications on Candida methylica Formate Dehydrogenase. Scientifica (Cairo) (2016) 0.75
Chemoenzymatic synthesis and antileukemic activity of novel C9- and C14-functionalized parthenolide analogs. Bioorg Med Chem (2016) 0.75
DNA assembler, an in vivo genetic method for rapid construction of biochemical pathways. Nucleic Acids Res (2008) 3.66
Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease. Mol Biosyst (2012) 2.01
Yeast surface display of trifunctional minicellulosomes for simultaneous saccharification and fermentation of cellulose to ethanol. Appl Environ Microbiol (2009) 1.55
New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin. Chem Commun (Camb) (2006) 1.53
Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster. Chem Biol (2006) 1.47
Adsorption of ionizable organic contaminants on multi-walled carbon nanotubes with different oxygen contents. J Hazard Mater (2010) 1.45
Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098. Chem Biol (2008) 1.41
Customized optimization of metabolic pathways by combinatorial transcriptional engineering. Nucleic Acids Res (2012) 1.41
In vitro reconstitution and crystal structure of p-aminobenzoate N-oxygenase (AurF) involved in aureothin biosynthesis. Proc Natl Acad Sci U S A (2008) 1.39
Recent developments in pyridine nucleotide regeneration. Curr Opin Biotechnol (2003) 1.36
A highly sensitive selection method for directed evolution of homing endonucleases. Nucleic Acids Res (2005) 1.34
Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing. Biotechnol Bioeng (2013) 1.28
Improving cellular malonyl-CoA level in Escherichia coli via metabolic engineering. Metab Eng (2009) 1.26
Seamless correction of the sickle cell disease mutation of the HBB gene in human induced pluripotent stem cells using TALENs. Biotechnol Bioeng (2013) 1.19
Discovery and characterization of novel d-xylose-specific transporters from Neurospora crassa and Pichia stipitis. Mol Biosyst (2010) 1.19
Rapid characterization and engineering of natural product biosynthetic pathways via DNA assembler. Mol Biosyst (2011) 1.18
Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways. J Biol Chem (2008) 1.17
Directed evolution of enzymes and biosynthetic pathways. Curr Opin Microbiol (2006) 1.16
Reconstitution and characterization of aminopyrrolnitrin oxygenase, a Rieske N-oxygenase that catalyzes unusual arylamine oxidation. J Biol Chem (2005) 1.15
A new class of arylamine oxygenases: evidence that p-aminobenzoate N-oxygenase (AurF) is a di-iron enzyme and further mechanistic studies. Chembiochem (2006) 1.15
Relaxing the nicotinamide cofactor specificity of phosphite dehydrogenase by rational design. Biochemistry (2003) 1.13
Engineering microbial factories for synthesis of value-added products. J Ind Microbiol Biotechnol (2011) 1.13
Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster. Nat Commun (2013) 1.09
Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches. Proc Natl Acad Sci U S A (2005) 1.08
Protein engineering in designing tailored enzymes and microorganisms for biofuels production. Curr Opin Biotechnol (2009) 1.08
Directed evolution of a thermostable phosphite dehydrogenase for NAD(P)H regeneration. Appl Environ Microbiol (2005) 1.06
Combinatorial design of a highly efficient xylose-utilizing pathway in Saccharomyces cerevisiae for the production of cellulosic biofuels. Appl Environ Microbiol (2012) 1.05
Biosynthesis of phloroglucinol. J Am Chem Soc (2005) 1.03
Refactoring the silent spectinabilin gene cluster using a plug-and-play scaffold. ACS Synth Biol (2013) 1.02
Heterologous expression, purification, and characterization of a highly active xylose reductase from Neurospora crassa. Appl Environ Microbiol (2005) 1.02
Cloning and characterization of a panel of constitutive promoters for applications in pathway engineering in Saccharomyces cerevisiae. Biotechnol Bioeng (2012) 1.02
Distinct structural elements dictate the specificity of the type III pentaketide synthase from Neurospora crassa. Chem Biol (2008) 1.01
Mutagenic inverted repeat assisted genome engineering (MIRAGE). Nucleic Acids Res (2008) 1.01
Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity. J Biol Chem (2004) 0.99
Directed evolution: an evolving and enabling synthetic biology tool. Curr Opin Chem Biol (2012) 0.99
Flow injection analysis of chemical oxygen demand (COD) by using a boron-doped diamond (BDD) electrode. Environ Sci Technol (2009) 0.99
Recent advances in targeted genome engineering in mammalian systems. Biotechnol J (2012) 0.97
Directed evolution of soluble single-chain human class II MHC molecules. J Mol Biol (2004) 0.96
Efficient regeneration of NADPH using an engineered phosphite dehydrogenase. Biotechnol Bioeng (2007) 0.95
Engineered biosynthesis of natural products in heterologous hosts. Chem Soc Rev (2015) 0.95
Applying an electric field in a built-in zero valent iron--anaerobic reactor for enhancement of sludge granulation. Water Res (2010) 0.94
DNA assembly techniques for next-generation combinatorial biosynthesis of natural products. J Ind Microbiol Biotechnol (2013) 0.94
FairyTALE: a high-throughput TAL effector synthesis platform. ACS Synth Biol (2013) 0.94
Three-dimensional imaging of normal skin and nonmelanoma skin cancer with cellular resolution using Gabor domain optical coherence microscopy. J Biomed Opt (2012) 0.94
Deciphering the late biosynthetic steps of antimalarial compound FR-900098. Chem Biol (2010) 0.93
Rapid identification of CD4+ T-cell epitopes using yeast displaying pathogen-derived peptide library. J Immunol Methods (2008) 0.93
Mechanistic studies on the conversion of arylamines into arylnitro compounds by aminopyrrolnitrin oxygenase: identification of intermediates and kinetic studies. Angew Chem Int Ed Engl (2006) 0.92
Overcoming glucose repression in mixed sugar fermentation by co-expressing a cellobiose transporter and a β-glucosidase in Saccharomyces cerevisiae. Mol Biosyst (2010) 0.92
Integrating plasmonic nanoparticles with TiO₂ photonic crystal for enhancement of visible-light-driven photocatalysis. Environ Sci Technol (2012) 0.92
Genome-scale consequences of cofactor balancing in engineered pentose utilization pathways in Saccharomyces cerevisiae. PLoS One (2011) 0.91
Directed evolution as a powerful synthetic biology tool. Methods (2012) 0.91
Directed evolution of the nonribosomal peptide synthetase AdmK generates new andrimid derivatives in vivo. Chem Biol (2011) 0.91
Biocatalyst development by directed evolution. Bioresour Technol (2012) 0.91
Direct cloning of large genomic sequences. Nat Biotechnol (2012) 0.91
Rapid creation of a novel protein function by in vitro coevolution. J Mol Biol (2005) 0.90
Recent advances in biocatalysis by directed enzyme evolution. Comb Chem High Throughput Screen (2006) 0.90
Industrial biotechnology: tools and applications. Biotechnol J (2009) 0.89
Selective reduction of xylose to xylitol from a mixture of hemicellulosic sugars. Metab Eng (2010) 0.89
Direct conversion of xylan to ethanol by recombinant Saccharomyces cerevisiae strains displaying an engineered minihemicellulosome. Appl Environ Microbiol (2012) 0.89
Directed evolution of a highly efficient cellobiose utilizing pathway in an industrial Saccharomyces cerevisiae strain. Biotechnol Bioeng (2013) 0.88
Effects of an electric field and zero valent iron on anaerobic treatment of azo dye wastewater and microbial community structures. Bioresour Technol (2010) 0.88
SunnyTALEN: a second-generation TALEN system for human genome editing. Biotechnol Bioeng (2013) 0.87
Directed evolution of homing endonuclease I-SceI with altered sequence specificity. Protein Eng Des Sel (2009) 0.87
Crystal structure and computational analyses provide insights into the catalytic mechanism of 2,4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens. J Biol Chem (2009) 0.87
Synthetic biology: putting synthesis into biology. Wiley Interdiscip Rev Syst Biol Med (2010) 0.87
Visible light photoelectrocatalysis with salicylic acid-modified TiO2 nanotube array electrode for p-nitrophenol degradation. J Hazard Mater (2008) 0.86
Directed evolution of orthogonal ligand specificity in a single scaffold. Angew Chem Int Ed Engl (2009) 0.86
Directed evolution of a cellobiose utilization pathway in Saccharomyces cerevisiae by simultaneously engineering multiple proteins. Microb Cell Fact (2013) 0.86
Evolution in reverse: engineering a D-xylose-specific xylose reductase. Chembiochem (2008) 0.85
Cooperative tandem catalysis by an organometallic complex and a metalloenzyme. Angew Chem Int Ed Engl (2014) 0.85
Rational pathway engineering of type I fatty acid synthase allows the biosynthesis of triacetic acid lactone from D-glucose in vivo. J Am Chem Soc (2004) 0.85
Production of long chain alcohols and alkanes upon coexpression of an acyl-ACP reductase and aldehyde-deformylating oxygenase with a bacterial type-I fatty acid synthase in E. coli. Mol Biosyst (2015) 0.85
Optimizing a biocatalyst for improved NAD(P)H regeneration: directed evolution of phosphite dehydrogenase. Comb Chem High Throughput Screen (2006) 0.84
Directed evolution of a cellodextrin transporter for improved biofuel production under anaerobic conditions in Saccharomyces cerevisiae. Biotechnol Bioeng (2014) 0.84
Probing the substrate specificity of aminopyrrolnitrin oxygenase (PrnD) by mutational analysis. J Bacteriol (2006) 0.84
Label-free fluorescent detection of Cu(II) ions based on DNA cleavage-dependent graphene-quenched DNAzymes. Chem Commun (Camb) (2011) 0.83
Detection of influenza A virus based on fluorescence resonance energy transfer from quantum dots to carbon nanotubes. Anal Chim Acta (2012) 0.83
Identification and characterization of the flavin:NADH reductase (PrnF) involved in a novel two-component arylamine oxygenase. J Bacteriol (2007) 0.83
Inverting the enantioselectivity of P450pyr monooxygenase by directed evolution. Chem Commun (Camb) (2010) 0.83
Characterization of the substrate specificity of PhlD, a type III polyketide synthase from Pseudomonas fluorescens. J Biol Chem (2006) 0.83
Interface engineering catalytic graphene for smart colorimetric biosensing. ACS Nano (2012) 0.83
Recent advances in biosynthesis of fatty acids derived products in Saccharomyces cerevisiae via enhanced supply of precursor metabolites. J Ind Microbiol Biotechnol (2014) 0.82
Formation of 2'-hydroxy-2,3',4,5'-tetrabromodipheyl ether (2'-HO-BDE68) from 2,4-dibromophenol in aqueous solution under simulated sunlight irradiation. Chemosphere (2011) 0.82
DNA assembler: a synthetic biology tool for characterizing and engineering natural product gene clusters. Methods Enzymol (2012) 0.82
Cloning and heterologous expression of the spectinabilin biosynthetic gene cluster from Streptomyces spectabilis. Mol Biosyst (2009) 0.82
Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration. Biochemistry (2012) 0.82
Investigation of the role of Arg301 identified in the X-ray structure of phosphite dehydrogenase. Biochemistry (2012) 0.82
A single-chain TALEN architecture for genome engineering. Mol Biosyst (2013) 0.82
Probing the molecular determinants of aniline dioxygenase substrate specificity by saturation mutagenesis. FEBS J (2007) 0.82
Construction and engineering of large biochemical pathways via DNA assembler. Methods Mol Biol (2013) 0.82
Exploiting genetic diversity by directed evolution: molecular breeding of type III polyketide synthases improves productivity. Mol Biosyst (2008) 0.82
Genotoxicity of quinolones: substituents contribution and transformation products QSAR evaluation using 2D and 3D models. Chemosphere (2013) 0.82
Coordinated induction of multi-gene pathways in Saccharomyces cerevisiae. Nucleic Acids Res (2012) 0.81
Engineering reprogrammable RNA-binding proteins for study and manipulation of the transcriptome. Mol Biosyst (2015) 0.81
High photocatalytic capability of self-assembled nanoporous WO3 with preferential orientation of (002) planes. Environ Sci Technol (2007) 0.81
Investigating host dependence of xylose utilization in recombinant Saccharomyces cerevisiae strains using RNA-seq analysis. Biotechnol Biofuels (2013) 0.81