Published in J Immunol on July 15, 2007
Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest (2010) 3.59
Checkpoints in lymphocyte development and autoimmune disease. Nat Immunol (2009) 1.84
Genetics of SLE: evidence from mouse models. Nat Rev Rheumatol (2010) 1.27
Regulation of the B cell receptor repertoire and self-reactivity by BAFF. J Immunol (2010) 1.19
RS rearrangement frequency as a marker of receptor editing in lupus and type 1 diabetes. J Exp Med (2008) 1.14
Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis. Immunology (2008) 1.10
The NZM2410-derived lupus susceptibility locus Sle2c1 increases Th17 polarization and induces nephritis in fas-deficient mice. Arthritis Rheum (2011) 1.02
B cell receptor editing in tolerance and autoimmunity. Ann N Y Acad Sci (2011) 1.01
Early onset of autoimmune disease by the retroviral integrase inhibitor raltegravir. Proc Natl Acad Sci U S A (2009) 0.99
Intrafollicular location of marginal zone/CD1d(hi) B cells is associated with autoimmune pathology in a mouse model of lupus. Lab Invest (2008) 0.91
Autoreactive marginal zone B cells enter the follicles and interact with CD4+ T cells in lupus-prone mice. BMC Immunol (2011) 0.90
Contributions of B cells to lupus pathogenesis. Mol Immunol (2013) 0.87
Spontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3. Lupus (2009) 0.85
Somatic mutagenesis in autoimmunity. Autoimmunity (2013) 0.84
Activation of rheumatoid factor-specific B cells is antigen dependent and occurs preferentially outside of germinal centers in the lupus-prone NZM2410 mouse model. J Immunol (2014) 0.84
Murine lupus susceptibility locus Sle2 activates DNA-reactive B cells through two sub-loci with distinct phenotypes. Genes Immun (2011) 0.83
Antibodies in a heavy chain knock-in mouse exhibit characteristics of early heavy chain rearrangement. J Immunol (2009) 0.81
Mechanisms of central tolerance for B cells. Nat Rev Immunol (2017) 0.81
Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens. Arthritis Rheum (2011) 0.80
B-cell tolerance in transplantation: is repertoire remodeling the answer? Expert Rev Clin Immunol (2009) 0.80
B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation. Transplant Rev (Orlando) (2010) 0.79
Antibodies that bind complex glycosaminoglycans accumulate in the Golgi. Proc Natl Acad Sci U S A (2013) 0.79
Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice. Autoimmunity (2013) 0.79
B-cell tolerance defects in the B6.Aec1/2 mouse model of Sjögren's syndrome. J Clin Immunol (2012) 0.79
Suppression of autoimmunity by CD5(+) IL-10-producing B cells in lupus-prone mice. Genes Immun (2015) 0.78
Overexpression of Fkbp11, a feature of lupus B cells, leads to B cell tolerance breakdown and initiates plasma cell differentiation. Immun Inflamm Dis (2015) 0.78
The combination of two Sle2 lupus-susceptibility loci and Cdkn2c deficiency leads to T-cell-mediated pathology in B6.Fas(lpr) mice. Genes Immun (2013) 0.78
Predominant role for activation-induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE. J Autoimmun (2015) 0.77
The role of rearrangement at the second Ig heavy chain locus in maintaining B cell tolerance to DNA. J Immunol (2008) 0.77
IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice. PLoS One (2016) 0.76
Genetic and cellular dissection of the activation of AM14 rheumatoid factor B cells in a mouse model of lupus. J Leukoc Biol (2015) 0.75
Phenotyping of autoreactive B cells with labeled nucleosomes in 56R transgenic mice. Sci Rep (2017) 0.75
Marginal-zone B cells. Nat Rev Immunol (2002) 4.87
PI3 kinase signals BCR-dependent mature B cell survival. Cell (2009) 4.43
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci U S A (2006) 3.70
Regulation of B cell tolerance by the lupus susceptibility gene Ly108. Science (2006) 2.58
Delayed lupus onset in (NZB x NZW)F1 mice expressing a human C-reactive protein transgene. Arthritis Rheum (2003) 2.53
Identification of the immunodominant protein and other proteins of the Bacillus anthracis exosporium. J Bacteriol (2003) 2.48
Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity (2008) 2.48
Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays. J Clin Invest (2005) 2.36
Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. Immunity (2006) 2.36
Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells. J Immunol (2010) 2.35
Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci U S A (2009) 2.31
Autoreactive B cells in the marginal zone that express dual receptors. J Exp Med (2002) 2.16
Maladaptive role of IL-6 in ischemic acute renal failure. J Am Soc Nephrol (2005) 2.07
DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN. J Am Soc Nephrol (2012) 1.93
Development and selection of marginal zone B cells. Immunol Rev (2004) 1.92
Systemic IFN-alpha drives kidney nephritis in B6.Sle123 mice. Eur J Immunol (2008) 1.84
Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells. J Immunol (2004) 1.76
The green tea polyphenol (-)-epigallocatechin-3-gallate ameliorates experimental immune-mediated glomerulonephritis. Kidney Int (2011) 1.72
Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1. Am J Physiol Renal Physiol (2011) 1.67
Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function. Eur J Immunol (2011) 1.67
Use of a novel elution regimen reveals the dominance of polyreactive antinuclear autoantibodies in lupus kidneys. Arthritis Rheum (2003) 1.63
Excreted urinary mediators in an animal model of experimental immune nephritis with potential pathogenic significance. Arthritis Rheum (2007) 1.62
Toll-like receptor signaling pathways--therapeutic opportunities. Mediators Inflamm (2010) 1.58
CD9 is a unique marker for marginal zone B cells, B1 cells, and plasma cells in mice. J Immunol (2002) 1.55
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. J Clin Invest (2009) 1.54
Characterization of the exosporium basal layer protein BxpB of Bacillus anthracis. J Bacteriol (2005) 1.52
Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. J Autoimmun (2009) 1.51
Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis. J Immunol (2007) 1.49
Marginal zone B cells in lymphocyte activation and regulation. Curr Opin Immunol (2005) 1.48
Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice. Arthritis Rheum (2012) 1.48
Nephrotic syndrome after bevacizumab: case report and literature review. Am J Kidney Dis (2007) 1.46
Yaa autoimmune phenotypes are conferred by overexpression of TLR7. Eur J Immunol (2008) 1.45
T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells. J Clin Invest (2005) 1.45
The integrin Mac-1 (CR3) mediates internalization and directs Bacillus anthracis spores into professional phagocytes. Proc Natl Acad Sci U S A (2008) 1.44
Non-uniform assembly of the Bacillus anthracis exosporium and a bottle cap model for spore germination and outgrowth. Mol Microbiol (2007) 1.42
Sympathetic nerves and the progression of chronic kidney disease during 5/6 nephrectomy: studies in sympathectomized rats. Clin Exp Pharmacol Physiol (2009) 1.42
Pillars article: generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin. Proc. Natl. Acad. Sci. USA, 81: 3180-3184, May 1984. J Immunol (2008) 1.40
Monoclonal antibodies for Bacillus anthracis spore detection and functional analyses of spore germination and outgrowth. J Immunol (2006) 1.35
CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages. Proc Natl Acad Sci U S A (2009) 1.34
Strain distribution pattern of susceptibility to immune-mediated nephritis. J Immunol (2004) 1.34
Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern. J Exp Med (2002) 1.28
The ExsY protein is required for complete formation of the exosporium of Bacillus anthracis. J Bacteriol (2006) 1.25
Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species. Am J Hypertens (2008) 1.25
SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature. PLoS One (2013) 1.25
Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus mice. J Exp Med (2004) 1.22
Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury. Kidney Int (2010) 1.22
Genetic dissection of SLE: SLE1 and FAS impact alternate pathways leading to lymphoproliferative autoimmunity. J Exp Med (2002) 1.22
CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus. J Immunol (2009) 1.22
Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. Am J Physiol Renal Physiol (2006) 1.22
Experimental anti-GBM disease as a tool for studying spontaneous lupus nephritis. Clin Immunol (2007) 1.21
Enhanced susceptibility to end-organ disease in the lupus-facilitating NZW mouse strain. Arthritis Rheum (2003) 1.18
Evidence for intranasal antinuclear autoantibodies in patients with chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol (2011) 1.17
Metabolic disturbances associated with systemic lupus erythematosus. PLoS One (2012) 1.15
Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus. J Clin Invest (2007) 1.14
Nephritogenic anti-DNA antibodies regulate gene expression in MRL/lpr mouse glomerular mesangial cells. Arthritis Rheum (2006) 1.14
Innate stimuli accentuate end-organ damage by nephrotoxic antibodies via Fc receptor and TLR stimulation and IL-1/TNF-alpha production. J Immunol (2006) 1.13
B cell TLR7 expression drives anti-RNA autoantibody production and exacerbates disease in systemic lupus erythematosus-prone mice. J Immunol (2012) 1.13
Receptor editing: an approach by autoreactive B cells to escape tolerance. The Journal of Experimental Medicine. 1993. 177: 999-1008. J Immunol (2011) 1.11
Deficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose. Mol Endocrinol (2008) 1.11
Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis. Arthritis Res Ther (2012) 1.10
Generation of B cell memory to the bacterial polysaccharide alpha-1,3 dextran. J Immunol (2009) 1.08
Altered Ig levels and antibody responses in mice deficient for the Fc receptor for IgM (FcμR). Proc Natl Acad Sci U S A (2012) 1.07
Editing anti-DNA B cells by Vlambdax. J Exp Med (2004) 1.06
Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen. Proc Natl Acad Sci U S A (2006) 1.05
Chronic graft-versus-host in Ig knockin transgenic mice abrogates B cell tolerance in anti-double-stranded DNA B cells. J Immunol (2002) 1.05
Epistatic suppression of systemic lupus erythematosus: fine mapping of Sles1 to less than 1 mb. J Immunol (2005) 1.05
Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models. Arthritis Res Ther (2011) 1.05
Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis. J Immunol (2009) 1.04
Regulation of anti-phosphatidylserine antibodies. Immunity (2003) 1.03
Secondary heavy chain rearrangement: a mechanism for generating anti-double-stranded DNA B cells. J Exp Med (2003) 1.03
Light chain editing generates polyreactive antibodies in chronic graft-versus-host reaction. J Exp Med (2006) 1.02
Macrophage subpopulations in systemic lupus erythematosus. Discov Med (2012) 1.02