PubRank

Chunhong Yan

Author PubWeight™ 19.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition. Nat Struct Mol Biol 2004 4.40
2 Structural evidence for substrate-induced synergism and half-sites reactivity in biotin carboxylase. Protein Sci 2008 1.45
3 Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem 2007 1.37
4 A small-molecule inhibitor of MDMX activates p53 and induces apoptosis. Mol Cancer Ther 2010 1.13
5 Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6. J Biol Chem 2010 1.12
6 A small-molecule p53 activator induces apoptosis through inhibiting MDMX expression in breast cancer cells. Neoplasia 2011 1.00
7 The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor. Mol Cell Biol 2012 0.98
8 MDM2 mediates ubiquitination and degradation of activating transcription factor 3. J Biol Chem 2010 0.97
9 The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins. J Biol Chem 2014 0.94
10 A novel high-throughput screening system identifies a small molecule repressive for matrix metalloproteinase-9 expression. Mol Pharmacol 2007 0.87
11 Inhibition of gastric tumor growth by a novel Hsp90 inhibitor. Biochem Pharmacol 2013 0.86
12 Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin. Antioxid Redox Signal 2014 0.85
13 Transgenic mice demonstrate novel promoter regions for tissue-specific expression of the urokinase receptor gene. Am J Pathol 2003 0.82
14 Rational protein engineering in action: the first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus. J Struct Biol 2007 0.81
15 Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists. Bioorg Med Chem Lett 2012 0.79
16 Determinants of Gli2 co-activation of wildtype and naturally truncated androgen receptors. Prostate 2014 0.79
17 Antitumor effects of all-trans-retinoic acid on cultured human pancreatic cancer cells. J Gastroenterol Hepatol 2006 0.78
18 [R-wave detection of ECG signal by using wavelet transform]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2006 0.75