Stephen A Duncan

Author PubWeight™ 89.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology 2010 6.40
2 Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ Res 2006 4.41
3 Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet 2003 3.91
4 Organogenesis and development of the liver. Dev Cell 2010 3.71
5 Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter. J Lipid Res 2006 3.67
6 GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc Natl Acad Sci U S A 2004 3.08
7 Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol 2008 2.34
8 A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proc Natl Acad Sci U S A 2006 2.32
9 Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A 2006 2.25
10 Modeling hepatitis C virus infection using human induced pluripotent stem cells. Proc Natl Acad Sci U S A 2012 2.20
11 ER stress controls iron metabolism through induction of hepcidin. Science 2009 2.18
12 Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest 2007 2.12
13 Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology 2006 2.04
14 Embryonic development of the liver. Hepatology 2005 2.01
15 GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol 2005 2.00
16 HNF4: a central regulator of hepatocyte differentiation and function. Hepatology 2003 1.84
17 The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med 2003 1.81
18 The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest 2005 1.78
19 Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Dev Biol 2007 1.75
20 The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism. Nat Med 2011 1.70
21 Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice. Hepatology 2012 1.68
22 Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum. BMC Dev Biol 2010 1.64
23 Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors. Hepatology 2004 1.64
24 Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest 2012 1.55
25 HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development 2011 1.50
26 Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat Chem Biol 2013 1.49
27 Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology 2008 1.47
28 GATA4 is essential for jejunal function in mice. Gastroenterology 2008 1.39
29 Pescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferation. J Biol Chem 2002 1.37
30 Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol 2006 1.35
31 Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors. BMC Dev Biol 2010 1.33
32 The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res 2010 1.32
33 JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. Hepatology 2012 1.25
34 GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature mice. Gastroenterology 2011 1.18
35 Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J 2007 1.14
36 Differentiation of hepatocytes from pluripotent stem cells. Curr Protoc Stem Cell Biol 2013 1.14
37 Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells. Anat Rec A Discov Mol Cell Evol Biol 2006 1.11
38 Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development. Mech Dev 2006 1.08
39 Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells. J Biol Chem 2007 1.08
40 Isoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cells. Anesthesiology 2010 1.01
41 Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies. Stem Cell Res 2012 1.00
42 Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem 2010 0.99
43 A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells. Mol Cell Proteomics 2012 0.94
44 Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination. Endocrine 2002 0.93
45 Generation of a conditionally null allele of hnf4alpha. Genesis 2002 0.92
46 Conserved enhancer in the serum response factor promoter controls expression during early coronary vasculogenesis. Circ Res 2004 0.90
47 Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice. Hepatology 2009 0.88
48 Design of the artificial acellular feeder layer for the efficient propagation of mouse embryonic stem cells. J Biol Chem 2008 0.88
49 Comparison of cardiomyogenic potential among human ESC and iPSC lines. Cell Transplant 2012 0.85
50 Induction of cardiomyogenesis in human embryonic stem cells by human embryonic stem cell-derived definitive endoderm. Stem Cells Dev 2011 0.80
51 Light chain 1 of microtubule-associated protein 1B can negatively regulate the action of Pes1. J Biol Chem 2007 0.77
52 Transcriptional control of hepatocyte differentiation. Prog Mol Biol Transl Sci 2010 0.75
53 Engineering liver tissue from induced pluripotent stem cells: a first step in generating new organs for transplantation? Hepatology 2013 0.75