Published in Gastroenterology on January 21, 2011
Intestinal development and differentiation. Exp Cell Res (2011) 1.44
GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest (2012) 1.41
DNA methylation is required for the control of stem cell differentiation in the small intestine. Genes Dev (2014) 1.31
GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol (2014) 1.03
Innate immunity in the small intestine. Curr Opin Gastroenterol (2012) 1.01
Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility. Endocrinology (2012) 1.01
Animal models of colorectal cancer. Cancer Metastasis Rev (2013) 0.99
GATA6 is required for proliferation, migration, secretory cell maturation, and gene expression in the mature mouse colon. Mol Cell Biol (2012) 0.93
Intronic cis-regulatory modules mediate tissue-specific and microbial control of angptl4/fiaf transcription. PLoS Genet (2012) 0.89
An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer. Oncogene (2013) 0.87
Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4. J Hepatol (2015) 0.85
Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice. Endocrinology (2013) 0.85
Transcription factors GATA4 and HNF4A control distinct aspects of intestinal homeostasis in conjunction with transcription factor CDX2. J Biol Chem (2014) 0.85
Zinc in gut-brain interaction in autism and neurological disorders. Neural Plast (2015) 0.83
Role of GATA factors in development, differentiation, and homeostasis of the small intestinal epithelium. Am J Physiol Gastrointest Liver Physiol (2014) 0.83
A gutsy task: generating intestinal tissue from human pluripotent stem cells. Dig Dis Sci (2013) 0.83
GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27. Biochim Biophys Acta (2014) 0.83
PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation. PLoS One (2012) 0.82
Characterization of the developing small intestine in the absence of either GATA4 or GATA6. BMC Res Notes (2014) 0.82
Adrenocortical zonation, renewal, and remodeling. Front Endocrinol (Lausanne) (2015) 0.80
GATA4 regulates epithelial cell proliferation to control intestinal growth and development in mice. Cell Mol Gastroenterol Hepatol (2016) 0.80
The emerging role of GATA transcription factors in development and disease. Expert Rev Mol Med (2016) 0.79
DNA Methylation Dynamics During Differentiation, Proliferation, and Tumorigenesis in the Intestinal Tract. Stem Cells Dev (2015) 0.79
Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine. BMC Mol Biol (2014) 0.79
Animal models of gastrointestinal and liver diseases. New mouse models for studying dietary prevention of colorectal cancer. Am J Physiol Gastrointest Liver Physiol (2014) 0.78
GATA factors in endocrine neoplasia. Mol Cell Endocrinol (2015) 0.77
Toying with fate: Redirecting the differentiation of adrenocortical progenitor cells into gonadal-like tissue. Mol Cell Endocrinol (2014) 0.77
REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis. Sci Rep (2015) 0.76
The miR-196b miRNA inhibits the GATA6 intestinal transcription factor and is upregulated in colon cancer patients. Oncotarget (2016) 0.75
Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation. EMBO J (2016) 0.75
Transcription Factor Trps1 Promotes Tubular Cell Proliferation after Ischemia-Reperfusion Injury through cAMP-Specific 3',5'-Cyclic Phosphodiesterase 4D and AKT. J Am Soc Nephrol (2016) 0.75
Essential role for the planarian intestinal GATA transcription factor in stem cells and regeneration. Dev Biol (2016) 0.75
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Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu Rev Physiol (2009) 7.29
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Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev (2003) 6.27
Notch signals control the fate of immature progenitor cells in the intestine. Nature (2005) 6.13
The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J Biol Chem (2000) 5.02
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc Natl Acad Sci U S A (2003) 4.76
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J Cell Biol (2007) 4.52
Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol (2005) 4.34
Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation. J Biol Chem (2004) 4.27
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium. Gastroenterology (2007) 4.17
Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin. Gastroenterology (2004) 3.39
Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium. EMBO J (2002) 3.30
Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep (2008) 3.03
Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev (2005) 2.94
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine. Development (2005) 2.56
Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine. Development (2005) 2.53
GATA-1-mediated proliferation arrest during erythroid maturation. Mol Cell Biol (2003) 2.52
The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium. Gastroenterology (2009) 2.01
Notes from some crypt watchers: regulation of renewal in the mouse intestinal epithelium. Curr Opin Cell Biol (1998) 1.83
Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol Cell Biol (2006) 1.71
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells. Exp Cell Res (2009) 1.64
GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium. Mol Cell Biol (2008) 1.56
A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation. Dev Biol (2008) 1.42
GATA4 is essential for jejunal function in mice. Gastroenterology (2008) 1.39
Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol (2006) 1.35
Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa. BMC Gastroenterol (2008) 1.28
GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest. J Biol Chem (1998) 1.24
Use of transgenic mice to study the routing of secretory proteins in intestinal epithelial cells: analysis of human growth hormone compartmentalization as a function of cell type and differentiation. J Cell Biol (1989) 1.20
GATA-2/estrogen receptor chimera regulates cytokine-dependent growth of hematopoietic cells through accumulation of p21(WAF1) and p27(Kip1) proteins. Blood (2002) 1.15
Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4. Am J Physiol Gastrointest Liver Physiol (2004) 1.08
GATA-4, GATA-5, and GATA-6 activate the rat liver fatty acid binding protein gene in concert with HNF-1alpha. Am J Physiol Gastrointest Liver Physiol (2004) 1.04
GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system. Oncogene (2009) 1.02
GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors. Dev Biol (2008) 1.02
Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine. Gut (2010) 1.01
Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol (2007) 0.96
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature (2010) 10.60
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology (2010) 6.40
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature (2010) 5.81
Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ Res (2006) 4.41
Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat Genet (2003) 3.91
Organogenesis and development of the liver. Dev Cell (2010) 3.71
Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter. J Lipid Res (2006) 3.67
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis. Proc Natl Acad Sci U S A (2004) 3.08
Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev Cell (2010) 2.84
Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. Dev Biol (2008) 2.34
A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proc Natl Acad Sci U S A (2006) 2.32
Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A (2006) 2.25
Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc Natl Acad Sci U S A (2011) 2.24
Distinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium. J Cell Biol (2011) 2.21
Modeling hepatitis C virus infection using human induced pluripotent stem cells. Proc Natl Acad Sci U S A (2012) 2.20
ER stress controls iron metabolism through induction of hepcidin. Science (2009) 2.18
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest (2007) 2.12
Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon. Gastroenterology (2006) 2.04
Embryonic development of the liver. Hepatology (2005) 2.01
GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol (2005) 2.00
HNF4: a central regulator of hepatocyte differentiation and function. Hepatology (2003) 1.84
Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1). Proc Natl Acad Sci U S A (2012) 1.83
The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat Med (2003) 1.81
The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. J Clin Invest (2005) 1.78
Atonal homolog 1 is a tumor suppressor gene. PLoS Biol (2009) 1.76
Development of the mammalian liver and ventral pancreas is dependent on GATA4. BMC Dev Biol (2007) 1.75
NHANES monitoring of serum 25-hydroxyvitamin D: a roundtable summary. J Nutr (2010) 1.74
Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol Cell Biol (2006) 1.71
The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism. Nat Med (2011) 1.70
SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells. Exp Cell Res (2009) 1.64
Culture of human pluripotent stem cells using completely defined conditions on a recombinant E-cadherin substratum. BMC Dev Biol (2010) 1.64
Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors. Hepatology (2004) 1.64
Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy. Gastroenterology (2007) 1.61
Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest (2012) 1.55
Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol (2010) 1.54
Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells. Gastroenterology (2010) 1.52
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells. Development (2011) 1.50
Identification of small molecules for human hepatocyte expansion and iPS differentiation. Nat Chem Biol (2013) 1.49
Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology (2008) 1.47
Gene-by-diet interactions influence calcium absorption and bone density in mice. J Bone Miner Res (2014) 1.46
Intestinal development and differentiation. Exp Cell Res (2011) 1.44
Vertebrate intestinal endoderm development. Dev Dyn (2011) 1.41
GATA4 is essential for jejunal function in mice. Gastroenterology (2008) 1.39
Vitamin D requirements: current and future. Am J Clin Nutr (2004) 1.37
Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D3 in the intestine and kidney of mice. Endocrinology (2003) 1.37
Pescadillo is essential for nucleolar assembly, ribosome biogenesis, and mammalian cell proliferation. J Biol Chem (2002) 1.37
Blimp1 regulates the transition of neonatal to adult intestinal epithelium. Nat Commun (2011) 1.36
Generation of mice harbouring a conditional loss-of-function allele of Gata6. BMC Dev Biol (2006) 1.35
Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors. BMC Dev Biol (2010) 1.33
Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis. Gut (2011) 1.33
The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circ Res (2010) 1.32
Vitamin D receptor (VDR) knockout mice reveal VDR-independent regulation of intestinal calcium absorption and ECaC2 and calbindin D9k mRNA. J Nutr (2003) 1.31
Stem cell-derived human intestinal organoids as an infection model for rotaviruses. MBio (2012) 1.27
Expansion of antigen-specific regulatory T cells with the topical vitamin d analog calcipotriol. J Immunol (2009) 1.26
JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. Hepatology (2012) 1.25
Notch in the intestine: regulation of homeostasis and pathogenesis. Annu Rev Physiol (2012) 1.15
Intestinal vitamin D receptor is required for normal calcium and bone metabolism in mice. Gastroenterology (2008) 1.15
Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J (2007) 1.14
Differentiation of hepatocytes from pluripotent stem cells. Curr Protoc Stem Cell Biol (2013) 1.14
High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout mice. J Nutr (2007) 1.13
Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells. Anat Rec A Discov Mol Cell Evol Biol (2006) 1.11
Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development. Mech Dev (2006) 1.08
Junctional adhesion molecule-A is critical for the formation of pseudocanaliculi and modulates E-cadherin expression in hepatic cells. J Biol Chem (2007) 1.08
Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4. Am J Physiol Gastrointest Liver Physiol (2004) 1.08
1,25 dihydroxyvitamin D-mediated orchestration of anticancer, transcript-level effects in the immortalized, non-transformed prostate epithelial cell line, RWPE1. BMC Genomics (2010) 1.05
Physical interaction between GATA-5 and hepatocyte nuclear factor-1alpha results in synergistic activation of the human lactase-phlorizin hydrolase promoter. J Biol Chem (2002) 1.05
Dietary vitamin D and vitamin D receptor level modulate epithelial cell proliferation and apoptosis in the prostate. Cancer Prev Res (Phila) (2011) 1.05
Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using penalized orthogonal-components regression. BMC Proc (2009) 1.03
GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors. Dev Biol (2008) 1.02
Gfi1-cells and circuits: unraveling transcriptional networks of development and disease. Curr Opin Hematol (2010) 1.01
Isoflurane preconditioning elicits competent endogenous mechanisms of protection from oxidative stress in cardiomyocytes derived from human embryonic stem cells. Anesthesiology (2010) 1.01
Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine. Gut (2010) 1.01
Hepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies. Stem Cell Res (2012) 1.00
Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells. J Biol Chem (2010) 0.99
An ABCA4 genomic deletion in patients with Stargardt disease. Hum Mutat (2003) 0.99
Animal models of colorectal cancer. Cancer Metastasis Rev (2013) 0.99
Intestinal crypts reproducibly expand in culture. J Surg Res (2012) 0.96
Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol (2007) 0.96
Case-control genome-wide association study of rheumatoid arthritis from Genetic Analysis Workshop 16 using penalized orthogonal-components regression-linear discriminant analysis. BMC Proc (2009) 0.96
Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion. J Biol Chem (2011) 0.94
A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells. Mol Cell Proteomics (2012) 0.94
Gene targeting in the mouse: advances in introduction of transgenes into the genome by homologous recombination. Endocrine (2002) 0.93
GATA6 is required for proliferation, migration, secretory cell maturation, and gene expression in the mature mouse colon. Mol Cell Biol (2012) 0.93
Effects of MAPK signaling on 1,25-dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2. J Cell Physiol (2009) 0.93
Generation of a transgenic mouse for colorectal cancer research with intestinal cre expression limited to the large intestine. Mol Cancer Res (2010) 0.93
Generation of a conditionally null allele of hnf4alpha. Genesis (2002) 0.92
SPDEF functions as a colorectal tumor suppressor by inhibiting β-catenin activity. Gastroenterology (2013) 0.91
Inadequate protein intake affects skeletal muscle transcript profiles in older humans. Am J Clin Nutr (2007) 0.91
Transgenic expression of the human Vitamin D receptor (hVDR) in the duodenum of VDR-null mice attenuates the age-dependent decline in calcium absorption. J Steroid Biochem Mol Biol (2007) 0.90
Control of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1alpha. Am J Physiol Gastrointest Liver Physiol (2004) 0.90
Conserved enhancer in the serum response factor promoter controls expression during early coronary vasculogenesis. Circ Res (2004) 0.90
The use of murine-derived fundic organoids in studies of gastric physiology. J Physiol (2015) 0.90