PubRank

Lawrence I Gilbert

Author PubWeight™ 33.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prothoracicotropic hormone regulates developmental timing and body size in Drosophila. Dev Cell 2007 2.33
2 The insect neuropeptide PTTH activates receptor tyrosine kinase torso to initiate metamorphosis. Science 2009 1.86
3 Discrete pulses of molting hormone, 20-hydroxyecdysone, during late larval development of Drosophila melanogaster: correlations with changes in gene activity. Dev Dyn 2006 1.70
4 Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone. Proc Natl Acad Sci U S A 2003 1.64
5 Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster. Proc Natl Acad Sci U S A 2002 1.61
6 Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis. Insect Biochem Mol Biol 2004 1.57
7 Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera. Dev Biol 2006 1.57
8 Juvenile hormone counteracts the bHLH-PAS transcription factors MET and GCE to prevent caspase-dependent programmed cell death in Drosophila. Development 2009 1.34
9 Neuroendocrine regulation of Drosophila metamorphosis requires TGFbeta/Activin signaling. Development 2011 1.33
10 Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis: a model of human neurodegenerative disease. Development 2007 1.23
11 Molecular evolution of the insect Halloween family of cytochrome P450s: phylogeny, gene organization and functional conservation. Insect Biochem Mol Biol 2007 1.18
12 A phosphoproteomics approach to elucidate neuropeptide signal transduction controlling insect metamorphosis. Insect Biochem Mol Biol 2009 1.16
13 Daphnia Halloween genes that encode cytochrome P450s mediating the synthesis of the arthropod molting hormone: evolutionary implications. BMC Evol Biol 2008 1.10
14 New players in the regulation of ecdysone biosynthesis. J Genet Genomics 2008 1.10
15 Identification, characterization and developmental expression of Halloween genes encoding P450 enzymes mediating ecdysone biosynthesis in the tobacco hornworm, Manduca sexta. Insect Biochem Mol Biol 2006 0.99
16 molting defective is required for ecdysone biosynthesis. Dev Biol 2005 0.97
17 Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila. BMC Genomics 2010 0.93
18 MET is required for the maximal action of 20-hydroxyecdysone during Bombyx metamorphosis. PLoS One 2012 0.92
19 Developmental expression of Manduca shade, the P450 mediating the final step in molting hormone synthesis. Mol Cell Endocrinol 2006 0.92
20 Drosophila is an inclusive model for human diseases, growth and development. Mol Cell Endocrinol 2008 0.91
21 Insect neuropeptide bursicon homodimers induce innate immune and stress genes during molting by activating the NF-κB transcription factor Relish. PLoS One 2012 0.88
22 Studies on the Black Box: incorporation of 3-oxo-7-dehydrocholesterol into ecdysteroids by Drosophila melanogaster and Manduca sexta. Insect Biochem Mol Biol 2009 0.86
23 Global identification of bursicon-regulated genes in Drosophila melanogaster. BMC Genomics 2008 0.86
24 Profiling of ecdysteroids in complex biological samples using liquid chromatography/ion trap mass spectrometry. Rapid Commun Mass Spectrom 2006 0.84
25 Hsc70 binds to ultraspiracle resulting in the upregulation of 20-hydroxyecdsone-responsive genes in Helicoverpa armigera. Mol Cell Endocrinol 2009 0.83
26 Ca2+ signaling in prothoracicotropic hormone-stimulated prothoracic gland cells of Manduca sexta: evidence for mobilization and entry mechanisms. Insect Biochem Mol Biol 2005 0.82
27 Protein kinase C modulates ecdysteroidogenesis in the prothoracic gland of the tobacco hornworm, Manduca sexta. Mol Cell Endocrinol 2006 0.82
28 Accessory gland as a site for prothoracicotropic hormone controlled ecdysone synthesis in adult male insects. PLoS One 2013 0.81
29 Manduca sexta prothoracicotropic hormone: evidence for a role beyond steroidogenesis. Arch Insect Biochem Physiol 2009 0.78
30 Developmental profiles of ecdysteroids, ecdysteroid receptor mRNAs and DNA binding properties of ecdysteroid receptors in the Ixodid tick Amblyomma americanum (L.). Insect Biochem Mol Biol 2002 0.75