PubRank

Zygmunt S Derewenda

Author PubWeight™ 52.86‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Toward rational protein crystallization: A Web server for the design of crystallizable protein variants. Protein Sci 2007 2.57
2 The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague. Structure 2004 2.53
3 The DCX-domain tandems of doublecortin and doublecortin-like kinase. Nat Struct Biol 2003 2.22
4 Coupling PAF signaling to dynein regulation: structure of LIS1 in complex with PAF-acetylhydrolase. Neuron 2004 1.51
5 B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes. Proteins 2006 1.47
6 The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle. Structure 2004 1.45
7 The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly. Structure 2007 1.36
8 The molecular structure and catalytic mechanism of a quorum-quenching N-acyl-L-homoserine lactone hydrolase. Proc Natl Acad Sci U S A 2005 1.33
9 The structure of the N-terminal domain of the product of the lissencephaly gene Lis1 and its functional implications. Structure 2004 1.25
10 PDZ tandem of human syntenin: crystal structure and functional properties. Structure 2003 1.21
11 The impact of Glu-->Ala and Glu-->Asp mutations on the crystallization properties of RhoGDI: the structure of RhoGDI at 1.3 A resolution. Acta Crystallogr D Biol Crystallogr 2002 1.21
12 The binding of the PDZ tandem of syntenin to target proteins. Biochemistry 2006 1.19
13 The structure and ligand binding properties of the B. subtilis YkoF gene product, a member of a novel family of thiamin/HMP-binding proteins. J Mol Biol 2004 1.17
14 Molecular roots of degenerate specificity in syntenin's PDZ2 domain: reassessment of the PDZ recognition paradigm. Structure 2003 1.13
15 The dimerization mechanism of LIS1 and its implication for proteins containing the LisH motif. J Mol Biol 2006 1.12
16 The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between macromolecular and small molecule crystallography. J Mol Biol 2004 1.11
17 The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein. J Cell Biol 2011 1.07
18 The role of entropy and polarity in intermolecular contacts in protein crystals. Acta Crystallogr D Biol Crystallogr 2009 1.06
19 p63RhoGEF couples Gα(q/11)-mediated signaling to Ca2+ sensitization of vascular smooth muscle contractility. Circ Res 2011 1.05
20 On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF. BMC Struct Biol 2009 1.04
21 Harvesting the high-hanging fruit: the structure of the YdeN gene product from Bacillus subtilis at 1.8 angstroms resolution. Acta Crystallogr D Biol Crystallogr 2004 1.04
22 The molecular basis of RhoA specificity in the guanine nucleotide exchange factor PDZ-RhoGEF. J Biol Chem 2006 1.00
23 The structure of the FERM domain of merlin, the neurofibromatosis type 2 gene product. Acta Crystallogr D Biol Crystallogr 2002 1.00
24 The impact of Lys-->Arg surface mutations on the crystallization of the globular domain of RhoGDI. Acta Crystallogr D Biol Crystallogr 2004 1.00
25 Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif . Biochemistry 2009 0.97
26 Bivalent peptides as models for multimeric targets of PDZ domains. Chembiochem 2007 0.95
27 The crystal structure of the reduced, Zn2+-bound form of the B. subtilis Hsp33 chaperone and its implications for the activation mechanism. Structure 2004 0.94
28 Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit. EMBO J 2013 0.93
29 Structure of a constitutively activated RhoA mutant (Q63L) at 1.55 A resolution. Acta Crystallogr D Biol Crystallogr 2003 0.91
30 Insights into the inhibition of the p90 ribosomal S6 kinase (RSK) by the flavonol glycoside SL0101 from the 1.5 Å crystal structure of the N-terminal domain of RSK2 with bound inhibitor. Biochemistry 2012 0.90
31 The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA. Protein Sci 2009 0.89
32 Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF. J Biol Chem 2011 0.87
33 Dissecting the thermodynamics of GAP-RhoA interactions. J Struct Biol 2008 0.86
34 Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains. Acta Crystallogr D Biol Crystallogr 2009 0.86
35 Probing the supramodular architecture of a multidomain protein: the structure of syntenin in solution. Structure 2005 0.86
36 Agonist-induced Ca2+ sensitization in smooth muscle: redundancy of Rho guanine nucleotide exchange factors (RhoGEFs) and response kinetics, a caged compound study. J Biol Chem 2013 0.86
37 Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein. Structure 2002 0.83
38 Preliminary crystallographic analysis of the complex of the human GTPase RhoA with the DH/PH tandem of PDZ-RhoGEF. Acta Crystallogr D Biol Crystallogr 2004 0.83
39 The DC-module of doublecortin: dynamics, domain boundaries, and functional implications. Proteins 2006 0.81
40 Structural features and chaperone activity of the NudC protein family. J Mol Biol 2011 0.81
41 The structure of DinB from Geobacillus stearothermophilus: a representative of a unique four-helix-bundle superfamily. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.80
42 Purification and crystallization of the N-terminal domain from the human doublecortin-like kinase. Acta Crystallogr D Biol Crystallogr 2003 0.79
43 Degenerate specificity of PDZ domains from RhoA-specific nucleotide exchange factors PDZRhoGEF and LARG. Acta Biochim Pol 2008 0.79
44 Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 Å resolution. Acta Crystallogr D Biol Crystallogr 2013 0.78
45 The unusual mechanism of inhibition of the p90 ribosomal S6 kinase (RSK) by flavonol rhamnosides. Biochim Biophys Acta 2013 0.78
46 Salvage or recovery of failed targets by mutagenesis to reduce surface entropy. Methods Mol Biol 2014 0.77
47 Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state. Acta Crystallogr D Biol Crystallogr 2007 0.76
48 The p90 ribosomal S6 kinase (RSK) is a mediator of smooth muscle contractility. PLoS One 2013 0.76
49 Abstractions, algorithms and data structures for structural bioinformatics in PyCogent. J Appl Crystallogr 2011 0.76
50 Assignment of 1H, 13C and 15N resonances of the N-terminal microtubule-binding domain of human doublecortin. J Biomol NMR 2003 0.75