Published in Expert Opin Ther Targets on August 01, 2007
Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase. Br J Cancer (2012) 1.35
Trial watch: Cardiac glycosides and cancer therapy. Oncoimmunology (2013) 1.21
The prince and the pauper. A tale of anticancer targeted agents. Mol Cancer (2008) 1.12
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Digitoxin and its analogs as novel cancer therapeutics. Exp Hematol Oncol (2012) 1.06
A Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides: Oligosaccharide Chain Length-Dependent Induction of Caspase-9-Mediated Apoptosis. ACS Med Chem Lett (2010) 1.05
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Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells. Toxicol Appl Pharmacol (2011) 0.92
A new view of carcinogenesis and an alternative approach to cancer therapy. Mol Med (2009) 0.90
Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77. Oncogene (2011) 0.86
Evaluating the cancer therapeutic potential of cardiac glycosides. Biomed Res Int (2014) 0.85
Digoxin, HIF-1, and cancer. Proc Natl Acad Sci U S A (2009) 0.82
Regression of Dalton's lymphoma in vivo via decline in lactate dehydrogenase and induction of apoptosis by a ruthenium(II)-complex containing 4-carboxy N-ethylbenzamide as ligand. Invest New Drugs (2008) 0.80
Real-time analysis of the effects of toxic, therapeutic and sub-therapeutic concentrations of digitoxin on lung cancer cells. Biosens Bioelectron (2014) 0.79
Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med (2015) 0.77
Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma. Nat Commun (2016) 0.77
Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa Cells. PLoS One (2016) 0.75
Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells. Sci Rep (2017) 0.75
"The Lower Threshold" phenomenon in tumor cells toward endogenous digitalis-like compounds: Responsible for tumorigenesis? J Carcinog (2012) 0.75
Repositioning approved drugs for the treatment of problematic cancers using a screening approach. PLoS One (2017) 0.75
Lanatoside C suppressed colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair. Oncotarget (2016) 0.75
Therapeutic concentrations of digitoxin inhibit endothelial focal adhesion kinase and angiogenesis induced by diverse growth factors. Br J Pharmacol (2017) 0.75