Published in Exp Hematol Oncol on April 05, 2012
Novel CD20 monoclonal antibodies for lymphoma therapy. J Hematol Oncol (2012) 1.30
Current management and prognostic features for gastrointestinal stromal tumor (GIST). Exp Hematol Oncol (2012) 1.23
Synergistic effect of paclitaxel and epigenetic agent phenethyl isothiocyanate on growth inhibition, cell cycle arrest and apoptosis in breast cancer cells. Cancer Cell Int (2013) 0.89
Rituximab and new regimens for indolent lymphoma: a brief update from 2012 ASCO Annual Meeting. Cancer Cell Int (2012) 0.88
Homozygous A polymorphism of the complement C1qA276 correlates with prolonged overall survival in patients with diffuse large B cell lymphoma treated with R-CHOP. J Hematol Oncol (2012) 0.84
Effect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemia. J Hematol Oncol (2012) 0.84
Phenethyl isothiocyanate and paclitaxel synergistically enhanced apoptosis and alpha-tubulin hyperacetylation in breast cancer cells. Exp Hematol Oncol (2014) 0.83
Intensity modulated radiotherapy for sinonasal malignancies with a focus on optic pathway preservation. J Hematol Oncol (2013) 0.79
Digoxin downregulates NDRG1 and VEGF through the inhibition of HIF-1α under hypoxic conditions in human lung adenocarcinoma A549 cells. Int J Mol Sci (2013) 0.79
Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate. Cancer Cell Int (2014) 0.79
Real-time analysis of the effects of toxic, therapeutic and sub-therapeutic concentrations of digitoxin on lung cancer cells. Biosens Bioelectron (2014) 0.79
Plant derived substances with anti-cancer activity: from folklore to practice. Front Plant Sci (2015) 0.78
Inactivation of Src-to-ezrin pathway: a possible mechanism in the ouabain-mediated inhibition of A549 cell migration. Biomed Res Int (2015) 0.78
Antitumor effects of naturally occurring cardiac glycosides convallatoxin and peruvoside on human ER+ and triple-negative breast cancers. Cell Death Discov (2017) 0.77
Digitoxin and its synthetic analog MonoD have potent antiproliferative effects on lung cancer cells and potentiate the effects of hydroxyurea and paclitaxel. Oncol Rep (2015) 0.77
Cardiac glycosides use and the risk of lung cancer: a nested case-control study. BMC Cancer (2014) 0.75
Repositioning approved drugs for the treatment of problematic cancers using a screening approach. PLoS One (2017) 0.75
Exploring targeted therapy of osteosarcoma using proteomics data. Onco Targets Ther (2017) 0.75
Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy. Genes (Basel) (2016) 0.75
Control of apoptosis and mitotic spindle checkpoint by survivin. Nature (1998) 8.60
Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell (2003) 7.48
Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth. Proc Natl Acad Sci U S A (2008) 4.79
Cell death by mitotic catastrophe: a molecular definition. Oncogene (2004) 4.75
Pleiotropic cell-division defects and apoptosis induced by interference with survivin function. Nat Cell Biol (1999) 4.11
ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence. FEBS J (2009) 4.05
Biochemistry of Na,K-ATPase. Annu Rev Biochem (2001) 4.00
Survivin: key regulator of mitosis and apoptosis and novel target for cancer therapeutics. Clin Cancer Res (2008) 3.92
Pathways of apoptotic and non-apoptotic death in tumour cells. Nat Rev Cancer (2004) 3.76
Death through a tragedy: mitotic catastrophe. Cell Death Differ (2008) 3.18
Targeting the checkpoint kinases: chemosensitization versus chemoprotection. Nat Rev Cancer (2004) 3.06
Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev (2008) 2.94
Novel therapeutic applications of cardiac glycosides. Nat Rev Drug Discov (2008) 2.80
Cardiac glycosides as novel cancer therapeutic agents. Mol Interv (2008) 2.70
Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension. EMBO J (2003) 2.70
Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth. Am J Physiol Cell Physiol (2007) 2.40
The pathways to tumor suppression via route p38. Trends Biochem Sci (2007) 2.15
Na+-K+--ATPase-mediated signal transduction: from protein interaction to cellular function. Mol Interv (2003) 2.13
Control of the G2/M transition. Mol Biotechnol (2006) 2.02
Anvirzel, an extract of Nerium oleander, induces cell death in human but not murine cancer cells. Anticancer Drugs (2000) 1.95
The TGF-beta paradox in human cancer: an update. Future Oncol (2009) 1.79
Cardiac glycosides stimulate Ca2+ increases and apoptosis in androgen-independent, metastatic human prostate adenocarcinoma cells. Cancer Res (2000) 1.69
Contemporary use of digoxin in the management of cardiovascular disorders. Circulation (2006) 1.67
p38 MAP kinase's emerging role as a tumor suppressor. Adv Cancer Res (2004) 1.64
Is digitalis a therapy for breast carcinoma? Oncol Rep (1999) 1.58
Retracted A cell cycle regulatory network controlling NF-kappaB subunit activity and function. EMBO J (2007) 1.58
Cyclin B1 depletion inhibits proliferation and induces apoptosis in human tumor cells. Oncogene (2004) 1.55
Evidence of a modifying influence of heart glucosides on the development of breast cancer. Anal Quant Cytol (1980) 1.53
Intracellular reactive oxygen species mediate the linkage of Na+/K+-ATPase to hypertrophy and its marker genes in cardiac myocytes. J Biol Chem (1999) 1.52
The clinical significance of Cyclin B1 and Wee1 expression in non-small-cell lung cancer. Ann Oncol (2004) 1.52
Src-mediated inter-receptor cross-talk between the Na+/K+-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen-activated protein kinases. J Biol Chem (2002) 1.51
Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases. J Biol Chem (1998) 1.51
Survivin dynamics increases at centromeres during G2/M phase transition and is regulated by microtubule-attachment and Aurora B kinase activity. J Cell Sci (2004) 1.51
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization. Proc Natl Acad Sci U S A (2005) 1.49
Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients. J Nat Prod (2005) 1.42
Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay. J Biol Chem (2006) 1.40
Regulation of c-SRC activity and function by the adapter protein CAS. Mol Cell Biol (2000) 1.40
Effects of bufalin and cinobufagin on the proliferation of androgen dependent and independent prostate cancer cells. Prostate (2003) 1.39
Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis. J Biol Chem (2003) 1.37
Digitalis-induced signaling by Na+/K+-ATPase in human breast cancer cells. Mol Pharmacol (2004) 1.36
Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex. Mol Biol Cell (2005) 1.36
Survivin gene expression in early-stage non-small cell lung cancer. J Pathol (2003) 1.35
Oleandrin suppresses activation of nuclear transcription factor-kappaB, activator protein-1, and c-Jun NH2-terminal kinase. Cancer Res (2000) 1.33
Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility. Mol Biol Cell (2004) 1.33
Cytotoxicity of digitoxin and related cardiac glycosides in human tumor cells. Anticancer Drugs (2001) 1.33
Erk1/2 MAP kinases are required for epidermal G2/M progression. J Cell Biol (2009) 1.32
Genome-wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray. Int J Cancer (2006) 1.32
Digitoxin as an anticancer agent with selectivity for cancer cells: possible mechanisms involved. Expert Opin Ther Targets (2007) 1.31
Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside. Integr Cancer Ther (2007) 1.30
Role of protein kinase C in the signal pathways that link Na+/K+-ATPase to ERK1/2. J Biol Chem (2001) 1.28
Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition. Cancer Res (2009) 1.27
Cardiac glycosides and breast cancer, revisited. N Engl J Med (1982) 1.26
Digitoxin mimics gene therapy with CFTR and suppresses hypersecretion of IL-8 from cystic fibrosis lung epithelial cells. Proc Natl Acad Sci U S A (2004) 1.25
The dual kinase complex FAK-Src as a promising therapeutic target in cancer. Onco Targets Ther (2010) 1.22
Centrosomal and cytoplasmic Cdc2/cyclin B1 activation precedes nuclear mitotic events. Exp Cell Res (2000) 1.22
Partial inhibition of Na+/K+-ATPase by ouabain induces the Ca2+-dependent expressions of early-response genes in cardiac myocytes. J Biol Chem (1996) 1.19
Digitoxin is a potential anticancer agent for several types of cancer. Med Hypotheses (1999) 1.17
Cardiac glycosides and breast cancer. Lancet (1979) 1.16
Inhibitory effects of digitalis on the proliferation of androgen dependent and independent prostate cancer cells. J Urol (2001) 1.15
Cellular basis for the species differences in sensitivity to cardiac glycosides (digitalis). J Cell Physiol (1986) 1.15
Oleandrin suppresses activation of nuclear transcription factor-kappa B and activator protein-1 and potentiates apoptosis induced by ceramide. Biochem Pharmacol (2003) 1.14
Ouabain sensitizes tumor cells but not normal cells to radiation. Int J Radiat Oncol Biol Phys (1988) 1.14
Ouabain modulates epithelial cell tight junction. Proc Natl Acad Sci U S A (2010) 1.13
Tiam1 is involved in the regulation of bufalin-induced apoptosis in human leukemia cells. Oncogene (1999) 1.13
Ras/Erk MAPK signaling in epidermal homeostasis and neoplasia. Cell Cycle (2007) 1.13
Inhibition of DNA topoisomerases I and II, and growth inhibition of breast cancer MCF-7 cells by ouabain, digoxin and proscillaridin A. Biol Pharm Bull (2006) 1.12
The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells. J Biol Chem (1996) 1.12
The prince and the pauper. A tale of anticancer targeted agents. Mol Cancer (2008) 1.12
Membrane cation transport and the control of proliferation of mammalian cells. Annu Rev Physiol (1978) 1.11
Sodium pump inhibition, enhanced calcium influx via sodium-calcium exchange, and positive inotropic response in cultured heart cells. Circ Res (1985) 1.10
Inhibition of export of fibroblast growth factor-2 (FGF-2) from the prostate cancer cell lines PC3 and DU145 by Anvirzel and its cardiac glycoside component, oleandrin. Biochem Pharmacol (2001) 1.09
Oleandrin-mediated inhibition of human tumor cell proliferation: importance of Na,K-ATPase alpha subunits as drug targets. Mol Cancer Ther (2009) 1.09
Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice. World J Gastroenterol (2007) 1.08
Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs. J Nat Prod (2009) 1.07
Oleandrin-mediated oxidative stress in human melanoma cells. J Exp Ther Oncol (2006) 1.07
Selective inhibitory effect of bufalin on growth of human tumor cells in vitro: association with the induction of apoptosis in leukemia HL-60 cells. Jpn J Cancer Res (1994) 1.06
Cardiac glycosides inhibit TNF-alpha/NF-kappaB signaling by blocking recruitment of TNF receptor-associated death domain to the TNF receptor. Proc Natl Acad Sci U S A (2005) 1.06
Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth. Nucleic Acids Res (2009) 1.06
Bufalin reduces the level of topoisomerase II in human leukemia cells and affects the cytotoxicity of anticancer drugs. Leuk Res (1997) 1.06
A Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides: Oligosaccharide Chain Length-Dependent Induction of Caspase-9-Mediated Apoptosis. ACS Med Chem Lett (2010) 1.05
Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells. Leuk Res (1995) 1.05
Oleandrin induces apoptosis in human, but not in murine cells: dephosphorylation of Akt, expression of FasL, and alteration of membrane fluidity. Mol Immunol (2006) 1.05
Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress. J Cell Sci (2003) 1.05
FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing. PLoS One (2011) 1.04
Src family kinase activity regulates adhesion, spreading and migration of pancreatic endocrine tumour cells. Endocr Relat Cancer (2007) 1.03
C5'-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity. ACS Med Chem Lett (2011) 1.02
Modifying the glycosidic linkage in digitoxin analogs provides selective cytotoxins. Bioorg Med Chem Lett (2008) 1.01
Ouabain binding to Na+,K+-ATPase relaxes cell attachment and sends a specific signal (NACos) to the nucleus. J Membr Biol (2004) 1.00
Overexpressions of Cyclin B1, cdc2, p16 and p53 in human breast cancer: the clinicopathologic correlations and prognostic implications. Yonsei Med J (2011) 0.99
Expression pattern of the AP-1 family in endometrial cancer: correlations with cell cycle regulators. J Cancer Res Clin Oncol (2001) 0.99
Structure-cytotoxic activity relationship for the toad poison bufadienolides. Bioorg Med Chem (1998) 0.98
The use of digitalis in heart failure. Curr Probl Cardiol (1996) 0.97
Characterization of the human Na,K-ATPase alpha 2 gene and identification of intragenic restriction fragment length polymorphisms. J Biol Chem (1989) 0.95
Digitalis toxicity: epidemiology and clinical use of serum concentration measurements. Am J Med (1975) 0.95
Digitalis and cancer. Lancet (1984) 0.94
Role of caveolae in ouabain-induced proliferation of cultured vascular smooth muscle cells of the synthetic phenotype. Am J Physiol Heart Circ Physiol (2004) 0.93
Synthesis and Evaluation of the α-D-/α-L-Rhamnosyl and Amicetosyl Digitoxigenin Oligomers as Anti-tumor Agents. ACS Med Chem Lett (2011) 0.93
Stereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell lung cancer cell. ACS Med Chem Lett (2011) 0.93
The de novo synthesis of oligosaccharides: application to the medicinal chemistry SAR-study of digitoxin. Curr Top Med Chem (2008) 0.92
LC/MS/MS analyses of an oleander extract for cancer treatment. Anal Chem (2000) 0.92
Sibling donor and recipient immune modulation with atorvastatin for the prophylaxis of acute graft-versus-host disease. J Clin Oncol (2013) 2.07
Reduced intensity haemopoietic stem-cell transplantation for treatment of non-malignant diseases in children. Lancet (2004) 2.05
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages. Immunity (2012) 2.01
Appalachian mountaintop mining particulate matter induces neoplastic transformation of human bronchial epithelial cells and promotes tumor formation. Environ Sci Technol (2014) 2.00
Mechanisms of nanoparticle-induced oxidative stress and toxicity. Biomed Res Int (2013) 1.97
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain. J Immunol (2009) 1.94
Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway. Cell Signal (2006) 1.87
Inflammation and lung cancer: roles of reactive oxygen/nitrogen species. J Toxicol Environ Health B Crit Rev (2008) 1.79
S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation. A novel antiapoptotic mechanism that suppresses apoptosis. J Biol Chem (2006) 1.61
Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation. Am J Physiol Cell Physiol (2010) 1.60
Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement. Blood (2009) 1.58
Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells. Am J Physiol Cell Physiol (2012) 1.54
Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts. J Toxicol Environ Health A (2010) 1.45
Molecular prognostic markers for adult acute myeloid leukemia with normal cytogenetics. J Hematol Oncol (2009) 1.44
Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1. J Biol Chem (2010) 1.43
A Shope Fibroma virus PYRIN-only protein modulates the host immune response. Virus Genes (2007) 1.41
Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies. Part Fibre Toxicol (2010) 1.38
Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination. Cancer Res (2006) 1.38
Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells. Toxicol Sci (2011) 1.34
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation. Infect Immun (2006) 1.23
STAT5 requires the N-domain to maintain hematopoietic stem cell repopulating function and appropriate lymphoid-myeloid lineage output. Exp Hematol (2007) 1.19
Potential role of apoptotic macrophages in pulmonary inflammation and fibrosis. J Cell Physiol (2003) 1.17
STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease. Blood (2009) 1.17
Lung cancer-associated JmjC domain protein mdig suppresses formation of tri-methyl lysine 9 of histone H3. Cell Cycle (2009) 1.16
Phosphatidylinositol 3-kinase/Akt positively regulates Fas (CD95)-mediated apoptosis in epidermal Cl41 cells. J Immunol (2006) 1.15
Phosphatidylinositol-3-kinase/akt regulates bleomycin-induced fibroblast proliferation and collagen production. Am J Respir Cell Mol Biol (2009) 1.14
Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation. J Pharmacol Exp Ther (2006) 1.14
Nitric oxide negatively regulates Fas CD95-induced apoptosis through inhibition of ubiquitin-proteasome-mediated degradation of FLICE inhibitory protein. J Biol Chem (2005) 1.13
Role of oxidative/nitrosative stress-mediated Bcl-2 regulation in apoptosis and malignant transformation. Ann N Y Acad Sci (2010) 1.11
Carbon nanotubes induce malignant transformation and tumorigenesis of human lung epithelial cells. Nano Lett (2011) 1.09
Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1. J Biol Chem (2009) 1.08
The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation. J Immunol (2008) 1.08
Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism. Biochem Pharmacol (2009) 1.08
Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells. Toxicol Appl Pharmacol (2012) 1.07
A Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides: Oligosaccharide Chain Length-Dependent Induction of Caspase-9-Mediated Apoptosis. ACS Med Chem Lett (2010) 1.05
Abnormal hematopoiesis in Gab2 mutant mice. Blood (2007) 1.04
C5'-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity. ACS Med Chem Lett (2011) 1.02
Role of S-nitrosylation in apoptosis resistance and carcinogenesis. Nitric Oxide (2008) 1.02
Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses. Nanotoxicology (2012) 1.01
RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer. Oncol Rep (2010) 1.01
Superoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosis. Carcinogenesis (2008) 1.00
Peroxide is a key mediator of Bcl-2 down-regulation and apoptosis induction by cisplatin in human lung cancer cells. Mol Pharmacol (2007) 1.00
Induction of neutrophil apoptosis and secondary necrosis during endotoxin-induced pulmonary inflammation in mice. J Cell Physiol (2002) 0.99
Nanomaterials in humans: identification, characteristics, and potential damage. Toxicol Pathol (2011) 0.99
Elevated AF1q expression is a poor prognostic marker for adult acute myeloid leukemia patients with normal cytogenetics. Am J Hematol (2009) 0.98
Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells. Nanotoxicology (2013) 0.98
Mitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitination. Biochem Pharmacol (2012) 0.97
MIR29B regulates expression of MLLT11 (AF1Q), an MLL fusion partner, and low MIR29B expression associates with adverse cytogenetics and poor overall survival in AML. Br J Haematol (2011) 0.97
Induction of secondary apoptosis, inflammation, and lung fibrosis after intratracheal instillation of apoptotic cells in rats. Am J Physiol Lung Cell Mol Physiol (2005) 0.97
Nitric oxide-mediated bcl-2 stabilization potentiates malignant transformation of human lung epithelial cells. Am J Respir Cell Mol Biol (2009) 0.96
Securinine, a myeloid differentiation agent with therapeutic potential for AML. PLoS One (2011) 0.95
Essential role of p53 in silica-induced apoptosis. Am J Physiol Lung Cell Mol Physiol (2004) 0.94
Synthesis and Evaluation of the α-D-/α-L-Rhamnosyl and Amicetosyl Digitoxigenin Oligomers as Anti-tumor Agents. ACS Med Chem Lett (2011) 0.93
Stereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell lung cancer cell. ACS Med Chem Lett (2011) 0.93
Multifunctional role of Bcl-2 in malignant transformation and tumorigenesis of Cr(VI)-transformed lung cells. PLoS One (2012) 0.92
Regulation of Fas (CD95)-induced apoptosis by nuclear factor-kappaB and tumor necrosis factor-alpha in macrophages. Am J Physiol Cell Physiol (2002) 0.92
Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells. Toxicol Appl Pharmacol (2011) 0.92
Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism. Apoptosis (2011) 0.91
Dependence of reactive oxygen species and FLICE inhibitory protein on lipofectamine-induced apoptosis in human lung epithelial cells. J Pharmacol Exp Ther (2008) 0.91
Identification of 6-benzylthioinosine as a myeloid leukemia differentiation-inducing compound. Cancer Res (2008) 0.91
Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation. Cancer Invest (2009) 0.90
Regulation of Fas (CD95)-induced apoptotic and necrotic cell death by reactive oxygen species in macrophages. J Cell Physiol (2005) 0.89
Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation. Apoptosis (2010) 0.88
Incidence and Pattern of Graft-versus-Host Disease in Patients Undergoing Allogeneic Transplantation after Nonmyeloablative Conditioning with Total Lymphoid Irradiation and Antithymocyte Globulin. Bone Marrow Res (2013) 0.88
Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1. Biochem Biophys Res Commun (2011) 0.88
Phase I study of temozolomide and laromustine (VNP40101M) in patients with relapsed or refractory leukemia. Clin Lymphoma Myeloma Leuk (2010) 0.87
Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis. Oncotarget (2014) 0.87
Th17 related cytokines in acute myeloid leukemia. Front Biosci (Landmark Ed) (2012) 0.87
Inhibition of TNF-alpha gene expression and bioactivity by site-specific transcription factor-binding oligonucleotides. Am J Physiol Lung Cell Mol Physiol (2002) 0.87
Exposure to carbon nanotubes leads to changes in the cellular biomechanics. Adv Healthc Mater (2013) 0.87
Antioxidant c-FLIP inhibits Fas ligand-induced NF-kappaB activation in a phosphatidylinositol 3-kinase/Akt-dependent manner. J Immunol (2011) 0.87
Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2. ACS Nano (2013) 0.86
Vanadium-induced apoptosis and pulmonary inflammation in mice: Role of reactive oxygen species. J Cell Physiol (2003) 0.86
Cross-talk between leukemic and endothelial cells promotes angiogenesis by VEGF activation of the Notch/Dll4 pathway. Carcinogenesis (2012) 0.85
Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis. Dev Biol (2013) 0.85
EGFR inhibition in non-small cell lung cancer: current evidence and future directions. Biomark Res (2013) 0.85
Favorable outcome for infant acute lymphoblastic leukemia after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant (2005) 0.84
Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells. Mol Biol Cell (2013) 0.83
Protective roles of NF-kappa B for chromium(VI)-induced cytotoxicity is revealed by expression of Ikappa B kinase-beta mutant. J Biol Chem (2001) 0.83
Vaccine delivery--current trends and future. Curr Drug Deliv (2006) 0.83
Antistaphylococcal nanocomposite films based on enzyme-nanotube conjugates. ACS Nano (2010) 0.83
AC927, a σ receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells. Mol Pharmacol (2011) 0.83
Higher busulfan dose intensity does not improve outcomes of patients undergoing allogeneic haematopoietic cell transplantation following fludarabine, busulfan-based reduced toxicity conditioning. Hematol Oncol (2011) 0.83
The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Arch Biochem Biophys (2013) 0.82
Therapeutic applications of carbon nanotubes: opportunities and challenges. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2014) 0.81
Pancytopenia related to dental adhesive in a young patient. Am J Stem Cells (2013) 0.81
Mutation of STAT1/3 binding sites in gp130(FXXQ) knock-in mice does not alter hematopoietic stem cell repopulation or self-renewal potential. Am J Stem Cells (2012) 0.81
Role of neutrophil apoptosis in vanadium-induced pulmonary inflammation in mice. J Environ Pathol Toxicol Oncol (2002) 0.81