Published in Science on August 03, 2007
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A label-free quantitative shotgun proteomics analysis of rice grain development. Proteome Sci (2011) 0.87
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The worker honeybee fat body proteome is extensively remodeled preceding a major life-history transition. PLoS One (2011) 0.86
Short Gel, Long Gradient Liquid Chromatography Tandem Mass Spectrometry to Discover Urinary Biomarkers of Chronic Pancreatitis. Open Proteomics J (2013) 0.86
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DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans. PLoS Genet (2014) 0.84
CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16. Elife (2013) 0.84
Immunohistochemical staining, laser capture microdissection, and filter-aided sample preparation-assisted proteomic analysis of target cell populations within tissue samples. Electrophoresis (2013) 0.84
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Tear proteomic analysis of Sjögren syndrome patients with dry eye syndrome by two-dimensional-nano-liquid chromatography coupled with tandem mass spectrometry. Sci Rep (2014) 0.82
Purification, crystallization and X-ray structures of the two manganese superoxide dismutases from Caenorhabditis elegans. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.81
The cellular geometry of growth drives the amino acid economy of Caenorhabditis elegans. Proc Biol Sci (2009) 0.81
Proteins and an inflammatory network expressed in colon tumors. J Proteome Res (2011) 0.81
RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2015) 0.81
Direct quantitation of peptide mixtures without standards using clusters formed by electrospray ionization mass spectrometry. Anal Chem (2009) 0.81
Cytoplasmic LSM-1 protein regulates stress responses through the insulin/IGF-1 signaling pathway in Caenorhabditis elegans. RNA (2015) 0.81
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The glycolytic enzyme, GPI, is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models. Cell Metab (2014) 0.80
Global Proteomics Analysis of the Response to Starvation in C. elegans. Mol Cell Proteomics (2015) 0.80
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Quantitative proteomics by amino acid labeling identifies novel NHR-49 regulated proteins in C. elegans. Worm (2012) 0.78
In-Depth Analyses of B Cell Signaling Through Tandem Mass Spectrometry of Phosphopeptides Enriched by PolyMAC. Int J Mass Spectrom (2015) 0.78
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RABA (reductive alkylation by acetone): a novel stable isotope labeling approach for quantitative proteomics. J Am Soc Mass Spectrom (2009) 0.77
A quantitative proteomics analysis of MCF7 breast cancer stem and progenitor cell populations. Proteomics (2015) 0.77
Mass spectrometry-based shotgun proteomic analysis of C. elegans protein complexes. WormBook (2014) 0.77
Characterization of PUD-1 and PUD-2, two proteins up-regulated in a long-lived daf-2 mutant. PLoS One (2013) 0.77
Reprogramming of energy metabolism as a driver of aging. Oncotarget (2016) 0.77
NeuCode Labeling in Nematodes: Proteomic and Phosphoproteomic Impact of Ascaroside Treatment in Caenorhabditis elegans. Mol Cell Proteomics (2015) 0.77
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Adapting proteostasis for disease intervention. Science (2008) 13.22
Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature (2003) 12.54
DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics. J Proteome Res (2003) 12.31
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy. Science (2010) 11.29
A proteomic view of the Plasmodium falciparum life cycle. Nature (2002) 10.65
The minimum information about a proteomics experiment (MIAPE). Nat Biotechnol (2007) 10.24
Isolation of amniotic stem cell lines with potential for therapy. Nat Biotechnol (2007) 9.67
Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii. Nature (2002) 8.92
A role for the P-body component GW182 in microRNA function. Nat Cell Biol (2005) 7.54
Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome. Science (2002) 7.49
The human CENP-A centromeric nucleosome-associated complex. Nat Cell Biol (2006) 6.85
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature (2007) 6.61
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The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell (2011) 6.05
A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses. Science (2005) 5.99
Phospho-regulation of kinetochore-microtubule attachments by the Aurora kinase Ipl1p. Cell (2002) 5.91
Opposing activities protect against age-onset proteotoxicity. Science (2006) 5.85
Secreted monocytic miR-150 enhances targeted endothelial cell migration. Mol Cell (2010) 5.77
Biological and chemical approaches to diseases of proteostasis deficiency. Annu Rev Biochem (2009) 5.23
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev (2004) 5.23
Aging and survival: the genetics of life span extension by dietary restriction. Annu Rev Biochem (2008) 5.22
Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation. Nature (2005) 5.15
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. Cell (2009) 5.05
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Cell (2006) 5.01
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Science (2004) 4.97
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell (2004) 4.91
The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. Nat Cell Biol (2006) 4.89
MS1, MS2, and SQT-three unified, compact, and easily parsed file formats for the storage of shotgun proteomic spectra and identifications. Rapid Commun Mass Spectrom (2004) 4.76
Automated approach for quantitative analysis of complex peptide mixtures from tandem mass spectra. Nat Methods (2004) 4.62
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat Cell Biol (2011) 4.59
Assigning function to yeast proteins by integration of technologies. Mol Cell (2003) 4.58
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol Cell (2009) 4.57
Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. Nature (2008) 4.52
Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell (2006) 4.50
Global analysis of protein palmitoylation in yeast. Cell (2006) 4.43
PRAK is essential for ras-induced senescence and tumor suppression. Cell (2007) 4.30
The biological impact of mass-spectrometry-based proteomics. Nature (2007) 4.24
Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell (2007) 4.22
Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP. Cell (2009) 4.22
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet (2005) 4.18
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The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem (2003) 4.13
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat Cell Biol (2013) 3.88
Probability-based validation of protein identifications using a modified SEQUEST algorithm. Anal Chem (2002) 3.86
Regulation of life-span by germ-line stem cells in Caenorhabditis elegans. Science (2002) 3.85
Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry. Science (2008) 3.77
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Global landscape of HIV-human protein complexes. Nature (2011) 3.70
Shotgun identification of protein modifications from protein complexes and lens tissue. Proc Natl Acad Sci U S A (2002) 3.70
Nuclear membrane proteins with potential disease links found by subtractive proteomics. Science (2003) 3.64
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Large-scale database searching using tandem mass spectra: looking up the answer in the back of the book. Nat Methods (2004) 3.62
A systematic approach to modeling, capturing, and disseminating proteomics experimental data. Nat Biotechnol (2003) 3.57
Molecular architecture of the human pre-mRNA 3' processing complex. Mol Cell (2009) 3.52
Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface. Mol Cell (2010) 3.44
Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline. Mol Cell (2009) 3.43
A quantitative analysis software tool for mass spectrometry-based proteomics. Nat Methods (2008) 3.35
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature (2011) 3.32
A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. J Cell Biol (2005) 3.18
Chemical and biological approaches synergize to ameliorate protein-folding diseases. Cell (2008) 3.11
Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proc Natl Acad Sci U S A (2007) 3.08
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Arginylation of beta-actin regulates actin cytoskeleton and cell motility. Science (2006) 3.05
A streamlined platform for high-content functional proteomics of primary human specimens. Nat Methods (2005) 3.00
Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture. Nat Biotechnol (2004) 2.98
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Architecture of the budding yeast kinetochore reveals a conserved molecular core. J Cell Biol (2003) 2.92
A systematic map of genetic variation in Plasmodium falciparum. PLoS Pathog (2006) 2.92
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Proteomic analysis of isolated chlamydomonas centrioles reveals orthologs of ciliary-disease genes. Curr Biol (2005) 2.86
TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium. Mol Biol Cell (2005) 2.76
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Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nat Chem Biol (2009) 2.70
IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Science (2013) 2.68
Tea4p links microtubule plus ends with the formin for3p in the establishment of cell polarity. Dev Cell (2005) 2.65
Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. Cell Metab (2007) 2.63
The application of mass spectrometry to membrane proteomics. Nat Biotechnol (2003) 2.61
Global analysis of protein sumoylation in Saccharomyces cerevisiae. J Biol Chem (2004) 2.60
LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation. Neuron (2009) 2.60
Swi1 and Swi3 are components of a replication fork protection complex in fission yeast. Mol Cell Biol (2004) 2.55
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The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions. J Proteome Res (2008) 2.53