Published in Biochemistry on August 11, 2007
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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis. J Cell Sci (2007) 2.95
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Appearance of immature/transitional B cells in HIV-infected individuals with advanced disease: correlation with increased IL-7. Proc Natl Acad Sci U S A (2006) 2.54
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Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells. Immunity (2006) 2.21
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A cocaine hydrolase engineered from human butyrylcholinesterase selectively blocks cocaine toxicity and reinstatement of drug seeking in rats. Neuropsychopharmacology (2008) 2.07
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Crystal structure of BMP-9 and functional interactions with pro-region and receptors. J Biol Chem (2005) 2.03
Bacillus anthracis edema and lethal toxin have different hemodynamic effects but function together to worsen shock and outcome in a rat model. J Infect Dis (2007) 2.01
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A mechanism of regulating transmembrane potassium flux through a ligand-mediated conformational switch. Cell (2002) 1.73
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly. Mol Cell (2003) 1.72
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Gene selection, alternative splicing, and post-translational processing regulate neuroligin selectivity for beta-neurexins. Biochemistry (2006) 1.67
TIP, a T-cell factor identified using high-throughput screening increases survival in a graft-versus-host disease model. Nat Biotechnol (2003) 1.63
Fluid support worsens outcome and negates the benefit of protective antigen-directed monoclonal antibody in a lethal toxin-infused rat Bacillus anthracis shock model. Crit Care Med (2007) 1.63
Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients. Mol Cell Proteomics (2008) 1.58
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Perturbations in B cell responsiveness to CD4+ T cell help in HIV-infected individuals. Proc Natl Acad Sci U S A (2003) 1.53
A discrete alcohol pocket involved in GIRK channel activation. Nat Neurosci (2009) 1.49
Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid. Proc Natl Acad Sci U S A (2005) 1.48
Separation of domain contacts is required for heterotetrameric assembly of functional NMDA receptors. J Neurosci (2011) 1.47
Impact of HIV on cell survival and antiviral activity of plasmacytoid dendritic cells. PLoS One (2007) 1.45
Deleterious effect of HIV-1 plasma viremia on B cell costimulatory function. J Immunol (2003) 1.44
Modeling analytical ultracentrifugation experiments with an adaptive space-time finite element solution of the Lamm equation. Biophys J (2005) 1.44
Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels. Neuron (2004) 1.43
The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex. J Mol Biol (2002) 1.43
Balancing efficacy and safety in the use of oral sedation in dental outpatients. J Am Dent Assoc (2006) 1.42
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Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis. J Biol Chem (2008) 1.40
Clinical significance of detecting elevated serum DcR3/TR6/M68 in malignant tumor patients. Int J Cancer (2003) 1.40
Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein. Virology (2008) 1.40
Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. PLoS Pathog (2016) 1.40
Novel peptide inhibitors of angiotensin-converting enzyme 2. J Biol Chem (2003) 1.36
Two overrepresented B cell populations in HIV-infected individuals undergo apoptosis by different mechanisms. Proc Natl Acad Sci U S A (2006) 1.36
The implementation of SOMO (SOlution MOdeller) in the UltraScan analytical ultracentrifugation data analysis suite: enhanced capabilities allow the reliable hydrodynamic modeling of virtually any kind of biomacromolecule. Eur Biophys J (2009) 1.35
A locking mechanism regulates RNA synthesis and host protein interaction by the hepatitis C virus polymerase. J Biol Chem (2008) 1.35
An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties. Chem Biol Interact (2008) 1.34
T4 AsiA blocks DNA recognition by remodeling sigma70 region 4. EMBO J (2004) 1.33
Andersen's syndrome mutation effects on the structure and assembly of the cytoplasmic domains of Kir2.1. Biochemistry (2006) 1.30
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Practice characteristics among dental anesthesia providers in the United States. Anesth Prog (2010) 1.28
BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors. Biochemistry (2007) 1.27
A flexible activin explains the membrane-dependent cooperative assembly of TGF-beta family receptors. Mol Cell (2004) 1.26
Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo. Proc Natl Acad Sci U S A (2013) 1.24
A structural basis for the assembly and functions of a viral polymer that inactivates multiple tumor suppressors. Cell (2012) 1.23
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Functional requirement for symmetric assembly of archaeal box C/D small ribonucleoprotein particles. J Mol Biol (2003) 1.22
Divergence of multimodular polyketide synthases revealed by a didomain structure. Nat Chem Biol (2012) 1.20
Neogenin interacts with hemojuvelin through its two membrane-proximal fibronectin type III domains. Biochemistry (2008) 1.20
Deamidation destabilizes and triggers aggregation of a lens protein, betaA3-crystallin. Protein Sci (2008) 1.20
Polycomb group targeting through different binding partners of RING1B C-terminal domain. Structure (2010) 1.19
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Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors. J Clin Invest (2011) 1.18
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Facile backbone structure determination of human membrane proteins by NMR spectroscopy. Nat Methods (2012) 1.16
Field observations of intraspecific agonistic behavior of two crayfish species, Orconectes rusticus and Orconectes virilis, in different habitats. Biol Bull (2003) 1.16
Paucity of HIV DNA methylation in latently infected, resting CD4+ T cells from infected individuals receiving antiretroviral therapy. J Virol (2012) 1.15
Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin. J Biol Chem (2002) 1.14
Development of a long-acting insulin analog using albumin fusion technology. Diabetes (2005) 1.14