Published in Nanomedicine on August 09, 2007
Delivery of siRNA therapeutics: barriers and carriers. AAPS J (2010) 2.15
Nanovehicular intracellular delivery systems. J Pharm Sci (2008) 1.10
Effect of molecular structure of cationic surfactants on biophysical interactions of surfactant-modified nanoparticles with a model membrane and cellular uptake. Langmuir (2009) 1.06
Nanotechnologies and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA. Br J Pharmacol (2009) 1.01
Concepts and practices used to develop functional PLGA-based nanoparticulate systems. Int J Nanomedicine (2013) 0.97
In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency. Nat Biotechnol (2015) 0.96
Effect of oleic acid modified polymeric bilayered nanoparticles on percutaneous delivery of spantide II and ketoprofen. J Control Release (2011) 0.94
Microneedle-mediated transcutaneous immunization with plasmid DNA coated on cationic PLGA nanoparticles. J Control Release (2012) 0.92
Biodegradable nanoparticles of mPEG-PLGA-PLL triblock copolymers as novel non-viral vectors for improving siRNA delivery and gene silencing. Int J Mol Sci (2012) 0.87
Intranasal delivery of cationic PLGA nano/microparticles-loaded FMDV DNA vaccine encoding IL-6 elicited protective immunity against FMDV challenge. PLoS One (2011) 0.87
Surface modification of TPGS-b-(PCL-ran-PGA) nanoparticles with polyethyleneimine as a co-delivery system of TRAIL and endostatin for cervical cancer gene therapy. Nanoscale Res Lett (2013) 0.84
Overview of the role of nanotechnological innovations in the detection and treatment of solid tumors. Int J Nanomedicine (2014) 0.82
Cell penetrating peptide-modified poly(lactic-co-glycolic acid) nanoparticles with enhanced cell internalization. Acta Biomater (2015) 0.82
Preparation, characterization, and transport of dexamethasone-loaded polymeric nanoparticles across a human placental in vitro model. Int J Pharm (2013) 0.81
Chitosan and glyceryl monooleate nanostructures containing gemcitabine: potential delivery system for pancreatic cancer treatment. AAPS PharmSciTech (2010) 0.81
Drug-loaded nano-microcapsules delivery system mediated by ultrasound-targeted microbubble destruction: A promising therapy method. Biomed Rep (2013) 0.80
Preparation, characterization, and in vitro and in vivo investigation of chitosan-coated poly (d,l-lactide-co-glycolide) nanoparticles for intestinal delivery of exendin-4. Int J Nanomedicine (2013) 0.80
Induction of mucosal immune responses and protection of cattle against direct-contact challenge by intranasal delivery with foot-and-mouth disease virus antigen mediated by nanoparticles. Int J Nanomedicine (2014) 0.78
Intranasal DNA Vaccine for Protection against Respiratory Infectious Diseases: The Delivery Perspectives. Pharmaceutics (2014) 0.78
Novel hydroxybutyl chitosan nanoparticles for siRNA delivery targeting tissue factor inhibits proliferation and induces apoptosis in human vascular smooth muscle cells. Mol Med Rep (2015) 0.78
Physicochemical features and transfection properties of chitosan/poloxamer 188/poly(D,L-lactide-co-glycolide) nanoplexes. Int J Nanomedicine (2014) 0.77
Solid lipid nanoparticle-based calix[n]arenes and calix-resorcinarenes as building blocks: synthesis, formulation and characterization. Int J Mol Sci (2013) 0.76
A blue fluorescent labeling technique utilizing micro- and nanoparticles for tracking in LIVE/DEAD(®) stained pathogenic biofilms of Staphylococcus aureus and Burkholderia cepacia. Int J Nanomedicine (2016) 0.75
Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems. Gene Ther (2017) 0.75
Hybrid inorganic-organic capsules for efficient intracellular delivery of novel siRNAs against influenza A (H1N1) virus infection. Sci Rep (2017) 0.75
pH-Responsive PLGA Nanoparticle for Controlled Payload Delivery of Diclofenac Sodium. J Funct Biomater (2016) 0.75
Multifunctional nanoparticles for prostate cancer therapy. AAPS PharmSciTech (2014) 0.75
Engineering the RNA-Nanobio Interface. Bioengineering (Basel) (2017) 0.75
Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment. Top Curr Chem (J) (2017) 0.75
Transforaminal lumbar interbody fusion: a safe technique with satisfactory three to five year results. Eur Spine J (2005) 2.32
Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies. Mol Biol Cell (2006) 1.95
Lectin-mediated drug targeting: history and applications. Adv Drug Deliv Rev (2004) 1.59
Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment. Neuropsychopharmacology (2007) 1.56
Nanoparticles--an efficient carrier for drug delivery into the hair follicles. Eur J Pharm Biopharm (2006) 1.56
Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C. Cell Tissue Res (2002) 1.33
A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: interaction with adverse childhood environment. Psychiatry Res (2007) 1.29
Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity. Mol Pharm (2007) 1.28
Prevalence of attention deficit-/hyperactivity disorder (ADHD) and comorbid disorders in young male prison inmates. Eur Arch Psychiatry Clin Neurosci (2004) 1.19
Towards an in vitro model of cystic fibrosis small airway epithelium: characterisation of the human bronchial epithelial cell line CFBE41o-. Cell Tissue Res (2005) 1.15
Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers. J Control Release (2006) 1.13
Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access. Mol Pharm (2010) 1.13
The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles. PLoS One (2012) 1.11
A level-1 pilot study to evaluate of ultraporous beta-tricalcium phosphate as a graft extender in the posterior correction of adolescent idiopathic scoliosis. Eur Spine J (2008) 1.09
Quantitative assessment of neuromotor function in adolescents with high functioning autism and Asperger Syndrome. J Autism Dev Disord (2007) 1.07
Nanoparticles and their interactions with the dermal barrier. Dermatoendocrinol (2009) 1.06
Interaction of metal oxide nanoparticles with lung surfactant protein A. Eur J Pharm Biopharm (2010) 1.04
Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile. Int J Pharm (2009) 1.04
Selective follicular targeting by modification of the particle sizes. J Control Release (2010) 1.03
Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus. Proc Natl Acad Sci U S A (2012) 1.03
Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A. Nanomedicine (2011) 1.02
In vitro assessment of transferrin-conjugated liposomes as drug delivery systems for inhalation therapy of lung cancer. Eur J Pharm Sci (2006) 0.98
Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages. Respir Res (2010) 0.97
Synthesis and characterization of human transferrin-stabilized gold nanoclusters. Nanotechnology (2011) 0.97
P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers. Cell Tissue Res (2006) 0.97
Human skin penetration of flufenamic acid: in vivo/in vitro correlation (deeper skin layers) for skin samples from the same subject. J Invest Dermatol (2002) 0.97
Depletion of alveolar macrophages by clodronate-liposomes aggravates ischemia-reperfusion injury of the lung. J Heart Lung Transplant (2005) 0.96
Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa: a first in vivo study in human patients. J Control Release (2012) 0.96
A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro. Mol Pharm (2010) 0.95
Nano- and microparticulate drug carriers for targeting of the inflamed intestinal mucosa. J Control Release (2012) 0.94
Nanoparticle geometry and surface orientation influence mode of cellular uptake. ACS Nano (2013) 0.93
Coupling of biotin-(poly(ethylene glycol))amine to poly(D,L-lactide-co-glycolide) nanoparticles for versatile surface modification. Bioconjug Chem (2007) 0.93
Large porous particle impingement on lung epithelial cell monolayers--toward improved particle characterization in the lung. Pharm Res (2003) 0.92
Mucus as a barrier to lipophilic drugs. Int J Pharm (2013) 0.92
Permeability of the reconstructed human epidermis model Episkin in comparison to various human skin preparations. Eur J Pharm Biopharm (2006) 0.92
Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo. Eur J Pharm Sci (2011) 0.90
Potential pitfalls in skin permeation experiments: influence of experimental factors and subsequent data evaluation. Eur J Pharm Biopharm (2008) 0.90
Cellular responses after exposure of lung cell cultures to secondary organic aerosol particles. Environ Sci Technol (2010) 0.89
Novel approaches for drug delivery systems in nanomedicine: effects of particle design and shape. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2011) 0.89
An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier. Eur J Pharm Biopharm (2010) 0.89
Pulmonary surfactant is indispensable in order to simulate the in vivo situation. Part Fibre Toxicol (2013) 0.88
Propidium iodide labeling of nanoparticles as a novel tool for the quantification of cellular binding and uptake. Nanomedicine (2011) 0.88
Conformational change of membrane proteins leads to shape changes of red blood cells. Bioelectrochemistry (2006) 0.87
Porcine alveolar epithelial cells in primary culture: morphological, bioelectrical and immunocytochemical characterization. Pharm Res (2006) 0.87
Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy. Eur J Pharm Biopharm (2005) 0.87
Interaction of inorganic nanoparticles with the skin barrier: current status and critical review. Nanomedicine (2012) 0.87
In vitro toxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response. Nanotoxicology (2013) 0.87
Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies. Cell Tissue Res (2002) 0.87
Hyaluronic acid-modified DOTAP/DOPE liposomes for the targeted delivery of anti-telomerase siRNA to CD44-expressing lung cancer cells. Oligonucleotides (2009) 0.86
Multiphoton microscopy for the investigation of dermal penetration of nanoparticle-borne drugs. J Invest Dermatol (2006) 0.86
Psychometric and psychopathological characterization of young male prison inmates with and without attention deficit/hyperactivity disorder. Eur Arch Psychiatry Clin Neurosci (2004) 0.86
Transfection with different colloidal systems: comparison of solid lipid nanoparticles and liposomes. J Control Release (2004) 0.86
Multilayer coating of gold nanoparticles with drug-polymer coadsorbates. Langmuir (2010) 0.86
Influence of particle size and material properties on mucociliary clearance from the airways. J Aerosol Med Pulm Drug Deliv (2010) 0.86
A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations. Eur J Pharm Biopharm (2010) 0.86
Effect of cationic lipid and matrix lipid composition on solid lipid nanoparticle-mediated gene transfer. Eur J Pharm Biopharm (2004) 0.86
Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells. Lung Cancer (2009) 0.86
A comparative evaluation of corneal epithelial cell cultures for assessing ocular permeability. Altern Lab Anim (2008) 0.85
Atomic force microscopy and analytical ultracentrifugation for probing nanomaterial protein interactions. ACS Nano (2012) 0.85
PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease. Eur J Pharm Biopharm (2013) 0.85
Bracing is an effective therapy for pectus carinatum: interim results. J Pediatr Surg (2013) 0.85
Penetration of quantum dot particles through human skin. J Biomed Nanotechnol (2010) 0.85
Non-invasive delivery of nanoparticles to hair follicles: a perspective for transcutaneous immunization. Vaccine (2013) 0.85
Mechanism and determinants of nanoparticle penetration through human skin. Nanoscale (2011) 0.85
In-silico model of skin penetration based on experimentally determined input parameters. Part I: experimental determination of partition and diffusion coefficients. Eur J Pharm Biopharm (2007) 0.85
Salbutamol is actively absorbed across human bronchial epithelial cell layers. Pulm Pharmacol Ther (2005) 0.85
Expression of ABC-transporters in human corneal tissue and the transformed cell line, HCE-T. J Ocul Pharmacol Ther (2007) 0.85
The use of reconstructed human epidermis for skin absorption testing: Results of the validation study. Altern Lab Anim (2008) 0.84
Selective antimicrobial activity associated with sulfur nanoparticles. J Biomed Nanotechnol (2011) 0.84