Published in Genome Res on August 10, 2007
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nat Genet (2012) 4.41
Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases. Free Radic Biol Med (2008) 2.14
Ancient mtDNA genetic variants modulate mtDNA transcription and replication. PLoS Genet (2009) 1.58
The role of mitochondria in the pathophysiology of skeletal muscle insulin resistance. Endocr Rev (2009) 1.57
Single-molecule LATE-PCR analysis of human mitochondrial genomic sequence variations. PLoS One (2009) 0.92
Gene expression pattern in transmitochondrial cytoplasmic hybrid cells harboring type 2 diabetes-associated mitochondrial DNA haplogroups. PLoS One (2011) 0.91
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Mitochondrial polymorphisms in rat genetic models of hypertension. Mamm Genome (2010) 0.88
A high-speed congenic strategy using first-wave male germ cells. PLoS One (2009) 0.87
Mitochondrial DNA variation in human metabolic rate and energy expenditure. Mitochondrion (2011) 0.87
Mito-nuclear co-evolution: the positive and negative sides of functional ancient mutations. Front Genet (2014) 0.85
Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study. PLoS One (2013) 0.85
Mitochondrial DNA variability modulates mRNA and intra-mitochondrial protein levels of HSP60 and HSP75: experimental evidence from cybrid lines. Cell Stress Chaperones (2008) 0.83
Cytoplasmic hybrid (cybrid) cell lines as a practical model for mitochondriopathies. Redox Biol (2014) 0.82
The mitochondrial genome sequence of Mus terricolor: comparison with Mus musculus domesticus and implications for xenomitochondrial mouse modeling. Gene (2008) 0.82
Construction of two novel reciprocal conplastic rat strains and characterization of cardiac mitochondria. Am J Physiol Heart Circ Physiol (2012) 0.81
Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly. J Alzheimers Dis (2012) 0.81
Renal angiotensin II type 1 receptor expression and associated hypertension in rats with minimal SHR nuclear genome. Physiol Rep (2013) 0.80
Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. J Mol Biol (2014) 0.79
Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry. Circ Cardiovasc Genet (2016) 0.78
Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains. Physiol Genomics (2012) 0.78
Mitochondrial Haplotypes Influence Metabolic Traits in Porcine Transmitochondrial Cybrids. Sci Rep (2015) 0.76
Primarily screening and analyzing ESTs differentially expressed in rats' primary liver cancer. Chin J Cancer Res (2013) 0.75
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Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med (2004) 18.86
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet (2005) 16.79
Mitochondrial dysfunction and type 2 diabetes. Science (2005) 10.25
Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques (2002) 7.56
Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med (1990) 7.13
Impaired fasting glucose and impaired glucose tolerance: implications for care. Diabetes Care (2007) 6.24
Systematic identification of human mitochondrial disease genes through integrative genomics. Nat Genet (2006) 4.67
Comprehensive association testing of common mitochondrial DNA variation in metabolic disease. Am J Hum Genet (2006) 2.60
A cluster of metabolic defects caused by mutation in a mitochondrial tRNA. Science (2004) 1.95
Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians. Am J Hum Genet (2007) 1.76
Pathogenic expression of homoplasmic mtDNA mutations needs a complex nuclear-mitochondrial interaction. Trends Genet (2003) 1.51
A high-yield preparative method for isolation of rat liver mitochondria. Anal Biochem (1977) 1.32
Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats. Nat Genet (2001) 1.26
Maternal transmission of diabetes. Diabet Med (2002) 1.16
Molecular mechanisms of mitochondrial diabetes (MIDD). Ann Med (2005) 1.14
Transgenic and recombinant resistin impair skeletal muscle glucose metabolism in the spontaneously hypertensive rat. J Biol Chem (2003) 1.10
Genetics of Cd36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension. J Clin Invest (1999) 1.08
Supersonic congenics? Nat Genet (1998) 0.92
Diminished synthesis of subunit a (ATP6) and altered function of ATP synthase and cytochrome c oxidase due to the mtDNA 2 bp microdeletion of TA at positions 9205 and 9206. Biochem J (2004) 0.92
A novel class of tests for the detection of mitochondrial DNA-mutation involvement in diseases. Am J Hum Genet (2003) 0.91
Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR. Hypertension (2001) 0.89
Is human Type 2 diabetes maternally inherited? Insights from an animal model. Diabet Med (2004) 0.85
Impaired noradrenaline-induced lipolysis in white fat of aP2-Ucp1 transgenic mice is associated with changes in G-protein levels. Biochem J (2002) 0.84
Homoplasmic mitochondrial DNA diseases as the paradigm to understand the tissue specificity and variable clinical severity of mitochondrial disorders. Mol Genet Metab (2000) 0.83
Inheritance of a mitochondrial DNA defect and impaired glucose tolerance in BHE/Cdb rats. Diabetologia (1999) 0.80
Noninsulin-dependent diabetes mellitus as a mitochondrial genomic disease. Proc Soc Exp Biol Med (1998) 0.80
Palmitate and glucose oxidation by diaphragm of rats with fructose-induced hypertriglyceridemia. Metabolism (1978) 0.80
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nat Genet (2005) 7.82
The protein kinase IKKepsilon regulates energy balance in obese mice. Cell (2009) 3.93
Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension (2004) 3.51
Recommendations for blood pressure measurement in humans: an AHA scientific statement from the Council on High Blood Pressure Research Professional and Public Education Subcommittee. J Clin Hypertens (Greenwich) (2005) 2.86
Hypoadiponectinemia is an independent risk factor for hypertension. Hypertension (2004) 2.65
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function. Nature (2011) 1.98
Effects of human C-reactive protein on pathogenesis of features of the metabolic syndrome. Hypertension (2011) 1.71
Leptin-receptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic nerve activation in a Caucasian male population. Hypertens Res (2008) 1.66
Lipolytic effects of B-type natriuretic peptide 1-32 in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol (2011) 1.59
Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B. Atherosclerosis (2011) 1.55
Maxillary incisor angulation and its effect on molar relationships. Angle Orthod (2007) 1.50
Nutritional therapy versus 6-mercaptopurine as maintenance therapy in patients with Crohn's disease. Dig Liver Dis (2012) 1.49
Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study. Hypertens Res (2009) 1.47
TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy. Nat Genet (2008) 1.45
Olmesartan ameliorates insulin sensitivity by modulating tumor necrosis factor-alpha and cyclic AMP in skeletal muscle. Hypertens Res (2005) 1.43
The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: From respiration to apoptosis. Mitochondrion (2011) 1.40
Molluscan shell evolution with review of shell calcification hypothesis. Comp Biochem Physiol B Biochem Mol Biol (2009) 1.40
Managing the aging man in Asia: a review. Int J Urol (2010) 1.36
Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes. Endocrinology (2008) 1.34
Intrinsic aerobic capacity sets a divide for aging and longevity. Circ Res (2011) 1.33
Regulation of oxidative phosphorylation, the mitochondrial membrane potential, and their role in human disease. J Bioenerg Biomembr (2008) 1.31
Sorafenib in platinum-treated patients with extensive stage small cell lung cancer: a Southwest Oncology Group (SWOG 0435) phase II trial. J Thorac Oncol (2010) 1.29
Insulin resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione. J Biol Chem (2012) 1.28
Regulatory role of B-1 B cells in chronic colitis. Int Immunol (2008) 1.25
Tissue-specific cytochrome c oxidase assembly defects due to mutations in SCO2 and SURF1. Biochem J (2005) 1.23
Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation. Immunity (2004) 1.22
Angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers and diabetes: a meta-analysis of placebo-controlled clinical trials. Am J Hypertens (2011) 1.21
Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nat Genet (2008) 1.19
Leukocyte adsorptive apheresis for the treatment of active ulcerative colitis: a prospective, uncontrolled, pilot study. Clin Gastroenterol Hepatol (2003) 1.18
Mitochondrial ATP synthase deficiency due to a mutation in the ATP5E gene for the F1 epsilon subunit. Hum Mol Genet (2010) 1.18
Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice. Diabetes (2012) 1.17
Salt sensitivity of Japanese from the viewpoint of gene polymorphism. Hypertens Res (2003) 1.17
Mitochondrial diseases and genetic defects of ATP synthase. Biochim Biophys Acta (2006) 1.14
Glycerophosphate-dependent hydrogen peroxide production by brown adipose tissue mitochondria and its activation by ferricyanide. J Bioenerg Biomembr (2002) 1.14
The impact of visit-to-visit variability in blood pressure on renal function. Hypertens Res (2011) 1.13
Uncoupling protein-1 is not leaky. Biochim Biophys Acta (2010) 1.13
Dependence of intestinal granuloma formation on unique myeloid DC-like cells. J Clin Invest (2007) 1.12
National trends in spinal fusion for cervical spondylotic myelopathy. Surg Neurol (2008) 1.11
TNF receptor type I-dependent activation of innate responses to reduce intestinal damage-associated mortality. Gastroenterology (2007) 1.11
YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation. Mol Biol Cell (2012) 1.10
Retrospective, multicentric study of 180 children with cytochrome C oxidase deficiency. Pediatr Res (2005) 1.10
Transgenic and recombinant resistin impair skeletal muscle glucose metabolism in the spontaneously hypertensive rat. J Biol Chem (2003) 1.10
Reduced respiratory control with ADP and changed pattern of respiratory chain enzymes as a result of selective deficiency of the mitochondrial ATP synthase. Pediatr Res (2004) 1.08
Curcumin has bright prospects for the treatment of inflammatory bowel disease. Curr Pharm Des (2009) 1.08
A new role for the von Hippel-Lindau tumor suppressor protein: stimulation of mitochondrial oxidative phosphorylation complex biogenesis. Carcinogenesis (2004) 1.07
Transpulmonary B-type natriuretic peptide uptake and cyclic guanosine monophosphate release in heart failure and pulmonary hypertension: the effects of sildenafil. J Am Coll Cardiol (2009) 1.07
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. FASEB J (2012) 1.07
Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance. Am J Physiol Endocrinol Metab (2008) 1.04
HIF and reactive oxygen species regulate oxidative phosphorylation in cancer. Carcinogenesis (2008) 1.03
Evidence for the critical role of interleukin-12 but not interferon-gamma in the pathogenesis of experimental colitis in mice. J Gastroenterol Hepatol (2003) 1.02
Anterograde transport of herpes simplex virus capsids in neurons by both separate and married mechanisms. J Virol (2011) 1.02
Evaluation of mitochondrial membrane potential using a computerized device with a tetraphenylphosphonium-selective electrode. Anal Biochem (2006) 1.01
Blood cell-derived induced pluripotent stem cells free of reprogramming factors generated by Sendai viral vectors. Stem Cells Transl Med (2013) 1.00
A unique B2 B cell subset in the intestine. J Exp Med (2008) 1.00
Occurrence of A-kinase anchor protein and associated cAMP-dependent protein kinase in the inner compartment of mammalian mitochondria. FEBS Lett (2006) 1.00
AMP-activated protein kinase α2 subunit is required for the preservation of hepatic insulin sensitivity by n-3 polyunsaturated fatty acids. Diabetes (2010) 0.99
Possible involvement of AMP-activated protein kinase in obesity resistance induced by respiratory uncoupling in white fat. FEBS Lett (2004) 0.98
Involvement of microsomal triglyceride transfer protein in nonalcoholic steatohepatitis in novel spontaneous mouse model. J Hepatol (2010) 0.97
Proton Pump Inhibitor Therapy before and after Endoscopic Submucosal Dissection: A Review. Diagn Ther Endosc (2012) 0.97
A suggested role for mitochondria in Noonan syndrome. Biochim Biophys Acta (2009) 0.97
Herpes simplex virus 1 protein kinase Us3 and major tegument protein UL47 reciprocally regulate their subcellular localization in infected cells. J Virol (2011) 0.96
Functional alteration of cytochrome c oxidase by SURF1 mutations in Leigh syndrome. Biochim Biophys Acta (2003) 0.95
Kynureninase is a novel candidate gene for hypertension in spontaneously hypertensive rats. Hypertens Res (2002) 0.95
Mitochondrial ATP synthase levels in brown adipose tissue are governed by the c-Fo subunit P1 isoform. FASEB J (2007) 0.95
Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. Nutr Metab (Lond) (2012) 0.94
Telmisartan-induced inhibition of vascular cell proliferation beyond angiotensin receptor blockade and peroxisome proliferator-activated receptor-gamma activation. Hypertension (2009) 0.94
Metabolic characterization of volume overload heart failure due to aorto-caval fistula in rats. Mol Cell Biochem (2011) 0.94
Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone. J Biol Chem (2002) 0.94
Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study. Am J Hypertens (2009) 0.94
Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice. Gastroenterology (2007) 0.93
Looking for endoscopic features of cytomegalovirus colitis: a study of 187 patients with active ulcerative colitis, positive and negative for cytomegalovirus. Inflamm Bowel Dis (2013) 0.93
Relationship of bradykinin B2 receptor gene polymorphism with essential hypertension and left ventricular hypertrophy. Hypertens Res (2004) 0.92
Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats. Clin Sci (Lond) (2011) 0.92
Diminished synthesis of subunit a (ATP6) and altered function of ATP synthase and cytochrome c oxidase due to the mtDNA 2 bp microdeletion of TA at positions 9205 and 9206. Biochem J (2004) 0.92
Dynamic genetic architecture of metabolic syndrome attributes in the rat. Physiol Genomics (2005) 0.92