Published in Annu Rev Genet on January 01, 2005
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The role of mitochondrial DNA mutations in mammalian aging. PLoS Genet (2007) 2.25
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The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations. Proc Natl Acad Sci U S A (2005) 1.88
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Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants. Nat Rev Genet (2009) 1.84
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Analysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex I. Mol Cell Biol (2007) 1.82
Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control. Antioxid Redox Signal (2011) 1.82
Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice. Proc Natl Acad Sci U S A (2011) 1.81
The coordination of nuclear and mitochondrial communication during aging and calorie restriction. Ageing Res Rev (2009) 1.79
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Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians. Am J Hum Genet (2007) 1.76
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Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell (2006) 1.75
Mitochondrial structure and function are disrupted by standard isolation methods. PLoS One (2011) 1.74
Mechanisms that regulate stem cell aging and life span. Cell Stem Cell (2013) 1.73
An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2014) 1.73
Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila. Proc Natl Acad Sci U S A (2012) 1.73
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression. J Clin Invest (2013) 1.72
Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements. PLoS One (2007) 1.72
Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev (2010) 1.71
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E2F transcription factor-1 regulates oxidative metabolism. Nat Cell Biol (2011) 1.70
Targeting mitochondria metabolism for cancer therapy. Nat Chem Biol (2015) 1.68
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Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2. PLoS Genet (2012) 1.67
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g. J Cell Biol (2009) 1.66
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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell (1999) 19.48
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med (2004) 18.86
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature (2005) 18.41
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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science (2004) 17.38
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