Differential regulation and substrate preferences in two peptide transporters of Saccharomyces cerevisiae.

PubWeight™: 1.34‹?› | Rank: Top 10%

🔗 View Article (PMC 2043388)

Published in Eukaryot Cell on August 10, 2007

Authors

Houjian Cai1, Melinda Hauser, Fred Naider, Jeffrey M Becker

Author Affiliations

1: Department of Microbiology, University of Tennessee, Knoxville, TN 37996-0845, USA.

Articles citing this

Regulation of amino acid, nucleotide, and phosphate metabolism in Saccharomyces cerevisiae. Genetics (2012) 1.64

Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway. Proc Natl Acad Sci U S A (2008) 1.11

Amino acids induce peptide uptake via accelerated degradation of CUP9, the transcriptional repressor of the PTR2 peptide transporter. J Biol Chem (2008) 1.00

A novel fungal family of oligopeptide transporters identified by functional metatranscriptomics of soil eukaryotes. ISME J (2011) 0.94

Peptides induce persistent signaling from endosomes by a nutrient transceptor. Nat Chem Biol (2012) 0.89

Analysing the substrate multispecificity of a proton-coupled oligopeptide transporter using a dipeptide library. Nat Commun (2013) 0.86

Specific analogues uncouple transport, signalling, oligo-ubiquitination and endocytosis in the yeast Gap1 amino acid transceptor. Mol Microbiol (2014) 0.84

The Ubiquitin ligase Ubr11 is essential for oligopeptide utilization in the fission yeast Schizosaccharomyces pombe. Eukaryot Cell (2012) 0.83

Evolutionary Advantage Conferred by an Eukaryote-to-Eukaryote Gene Transfer Event in Wine Yeasts. Mol Biol Evol (2015) 0.81

A dipeptide transporter from the arbuscular mycorrhizal fungus Rhizophagus irregularis is upregulated in the intraradical phase. Front Plant Sci (2014) 0.80

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa. PLoS One (2014) 0.80

Roles of different peptide transporters in nutrient acquisition in Candida albicans. Eukaryot Cell (2013) 0.79

Heat stress-induced Cup9-dependent transcriptional regulation of SIR2. Mol Cell Biol (2014) 0.77

Elongator-dependent modification of cytoplasmic tRNALysUUU is required for mitochondrial function under stress conditions. Nucleic Acids Res (2015) 0.77

L-Methionine repressible promoters for tuneable gene expression in Trichoderma reesei. Microb Cell Fact (2015) 0.76

Functional implications and ubiquitin-dependent degradation of the peptide transporter Ptr2 in Saccharomyces cerevisiae. Eukaryot Cell (2014) 0.75

Horizontal gene transfer drives adaptive colonization of apple trees by the fungal pathogen Valsa mali. Sci Rep (2016) 0.75

Halo Assay for Toxic Peptides and Other Compounds in Microorganisms. Bio Protoc (2016) 0.75

Articles cited by this

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast (1998) 23.00

Genealogy of principal strains of the yeast genetic stock center. Genetics (1986) 6.00

A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast. Nucleic Acids Res (2002) 5.38

Genetic regulation of nitrogen metabolism in the fungi. Microbiol Mol Biol Rev (1997) 3.00

A tripeptide 'anticodon' deciphers stop codons in messenger RNA. Nature (2000) 2.90

Identification of sequences responsible for transcriptional activation of the allantoate permease gene in Saccharomyces cerevisiae. Mol Cell Biol (1989) 2.45

The PTR family: a new group of peptide transporters. Mol Microbiol (1995) 2.02

The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain. EMBO J (1999) 2.00

The GLN3 gene product is required for transcriptional activation of allantoin system gene expression in Saccharomyces cerevisiae. J Bacteriol (1990) 1.98

Transcriptional regulation of the DAL5 gene in Saccharomyces cerevisiae. J Bacteriol (1987) 1.96

Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature (2000) 1.90

Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids. Mol Cell Biol (1999) 1.83

Genetic evidence for Gln3p-independent, nitrogen catabolite repression-sensitive gene expression in Saccharomyces cerevisiae. J Bacteriol (1995) 1.72

The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. EMBO J (1998) 1.71

Saccharomyces cerevisiae GATA sequences function as TATA elements during nitrogen catabolite repression and when Gln3p is excluded from the nucleus by overproduction of Ure2p. J Biol Chem (2000) 1.68

Structure and transcription of the allantoate permease gene (DAL5) from Saccharomyces cerevisiae. J Bacteriol (1988) 1.59

Gln3 phosphorylation and intracellular localization in nutrient limitation and starvation differ from those generated by rapamycin inhibition of Tor1/2 in Saccharomyces cerevisiae. J Biol Chem (2003) 1.52

Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene. Mol Cell Biol (1994) 1.49

Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids. Mol Cell Biol (2001) 1.49

Ureidosuccinate is transported by the allantoate transport system in Saccharomyces cerevisiae. J Bacteriol (1987) 1.41

Harnessing natural diversity to probe metabolic pathways. PLoS Genet (2005) 1.39

Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae. Genetics (1999) 1.34

Genomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae. Genetics (2005) 1.28

An oligopeptide transport gene from Candida albicans. Microbiology (1997) 1.23

Allantoate transport in Saccharomyces cerevisiae. J Bacteriol (1979) 1.21

Regulation of dipeptide transport in Saccharomyces cerevisiae by micromolar amino acid concentrations. J Bacteriol (1987) 1.21

Regulation of allantoate transport in wild-type and mutant strains of Saccharomyces cerevisiae. J Bacteriol (1987) 1.18

Suppressors of ssy1 and ptr3 null mutations define novel amino acid sensor-independent genes in Saccharomyces cerevisiae. Genetics (2001) 1.17

Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression. J Biol Chem (2005) 1.16

Prions of yeast and fungi. Proteins as genetic material. J Biol Chem (1999) 1.13

Multiplicity and regulation of genes encoding peptide transporters in Saccharomyces cerevisiae. Mol Membr Biol (2001) 1.12

The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol (2001) 1.10

PTR3, a novel gene mediating amino acid-inducible regulation of peptide transport in Saccharomyces cerevisiae. Mol Microbiol (1998) 1.08

A tripeptide discriminator for stop codon recognition. FEBS Lett (2002) 1.07

Isolation and characterization of S. cerevisiae mutants deficient in amino acid-inducible peptide transport. Curr Genet (1991) 1.07

Microbial proteases in peptide synthesis: approaches and applications. Appl Microbiol Biotechnol (2005) 0.96

Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp1p and Stp2p. Yeast (2004) 0.92

A novel Rtg2p activity regulates nitrogen catabolism in yeast. Proc Natl Acad Sci U S A (2001) 0.91

Genome-wide expression analysis of genes affected by amino acid sensor Ssy1p in Saccharomyces cerevisiae. Curr Genet (2002) 0.90

Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia. J Biol Chem (2001) 0.89

A novel cis-acting cysteine-responsive regulatory element of the gene for the high-affinity glutathione transporter of Saccharomyces cerevisiae. Mol Genet Genomics (2002) 0.85

Expression of the UGA4 gene encoding the delta-aminolevulinic and gamma-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems. Arch Microbiol (2005) 0.84

Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B. J Med Chem (2002) 0.82

Articles by these authors

Candida albicans septin mutants are defective for invasive growth and virulence. Infect Immun (2003) 1.58

A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry (2002) 1.48

Harnessing natural diversity to probe metabolic pathways. PLoS Genet (2005) 1.39

Analysis of protein solvent accessible surfaces by photochemical oxidation and mass spectrometry. Anal Chem (2004) 1.33

Genomewide screen reveals a wide regulatory network for di/tripeptide utilization in Saccharomyces cerevisiae. Genetics (2005) 1.28

An oligopeptide transporter gene family in Arabidopsis. Plant Physiol (2002) 1.25

Genome-scale gene function prediction using multiple sources of high-throughput data in yeast Saccharomyces cerevisiae. OMICS (2004) 1.25

Peptide transport in plants. Trends Plant Sci (2002) 1.20

Wangiella (Exophiala) dermatitidis WdChs5p, a class V chitin synthase, is essential for sustained cell growth at temperature of infection. Eukaryot Cell (2004) 1.18

Protein surface mapping by chemical oxidation: structural analysis by mass spectrometry. Anal Biochem (2003) 1.17

The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors. Peptides (2004) 1.17

Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model. Proc Natl Acad Sci U S A (2010) 1.10

The 2F5 epitope is helical in the HIV-1 entry inhibitor T-20. Biochemistry (2005) 1.06

The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide. J Mol Biol (2011) 1.04

A fluorescent alpha-factor analogue exhibits multiple steps on binding to its G protein coupled receptor in yeast. Biochemistry (2004) 1.03

The first extracellular loop of the Saccharomyces cerevisiae G protein-coupled receptor Ste2p undergoes a conformational change upon ligand binding. J Biol Chem (2007) 0.99

Identification of ligand binding regions of the Saccharomyces cerevisiae alpha-factor pheromone receptor by photoaffinity cross-linking. Biochemistry (2004) 0.98

The membrane proximal external region of the HIV-1 envelope glycoprotein gp41 contributes to the stabilization of the six-helix bundle formed with a matching N' peptide. Biochemistry (2008) 0.98

Unnatural amino acid replacement in a yeast G protein-coupled receptor in its native environment. Biochemistry (2008) 0.98

Identification of a contact region between the tridecapeptide alpha-factor mating pheromone of Saccharomyces cerevisiae and its G protein-coupled receptor by photoaffinity labeling. Biochemistry (2002) 0.97

An optimally constrained V3 peptide is a better immunogen than its linear homolog or HIV-1 gp120. Virology (2010) 0.94

Residues in the first extracellular loop of a G protein-coupled receptor play a role in signal transduction. J Biol Chem (2002) 0.93

Tyr266 in the sixth transmembrane domain of the yeast alpha-factor receptor plays key roles in receptor activation and ligand specificity. Biochemistry (2002) 0.92

Oligomerization of the yeast alpha-factor receptor: implications for dominant negative effects of mutant receptors. J Biol Chem (2006) 0.92

Nutrient regulation of oligopeptide transport in Saccharomyces cerevisiae. Microbiology (2006) 0.91

Biosynthesis and NMR analysis of a 73-residue domain of a Saccharomyces cerevisiae G protein-coupled receptor. Biochemistry (2005) 0.91

Interacting residues in an activated state of a G protein-coupled receptor. J Biol Chem (2005) 0.89

NMR studies in dodecylphosphocholine of a fragment containing the seventh transmembrane helix of a G-protein-coupled receptor from Saccharomyces cerevisiae. Biophys J (2007) 0.88

Substrate preference is altered by mutations in the fifth transmembrane domain of Ptr2p, the di/tri-peptide transporter of Saccharomyces cerevisiae. Mol Membr Biol (2005) 0.88

Affinity purification and characterization of a G-protein coupled receptor, Saccharomyces cerevisiae Ste2p. Protein Expr Purif (2007) 0.87

Cross-linking of a DOPA-containing peptide ligand into its G protein-coupled receptor. Biochemistry (2009) 0.86

Differential interactions of fluorescent agonists and antagonists with the yeast G protein coupled receptor Ste2p. J Mol Biol (2011) 0.85

Selective labeling of a membrane peptide with 15N-amino acids using cells grown in rich medium. Biopolymers (2006) 0.85

Completely different amyloidogenic potential of nearly identical peptide fragments. Biopolymers (2003) 0.85

Expression and biophysical analysis of two double-transmembrane domain-containing fragments from a yeast G protein-coupled receptor. Biopolymers (2008) 0.84

Synthesis of a-factor peptide from Saccharomyces cerevisiae and photoactive analogues via Fmoc solid phase methodology. Bioorg Med Chem (2010) 0.84

Identification of residue-to-residue contact between a peptide ligand and its G protein-coupled receptor using periodate-mediated dihydroxyphenylalanine cross-linking and mass spectrometry. J Biol Chem (2010) 0.84

Sequences in the intracellular loops of the yeast pheromone receptor Ste2p required for G protein activation. Biochemistry (2003) 0.84

HIV-1 peptide vaccine candidates: selecting constrained V3 peptides with highest affinity to antibody 447-52D. Biochemistry (2009) 0.84

Structure of a double transmembrane fragment of a G-protein-coupled receptor in micelles. Biophys J (2009) 0.83

Identification of residues involved in homodimer formation located within a β-strand region of the N-terminus of a Yeast G protein-coupled receptor. J Recept Signal Transduct Res (2012) 0.83

Double-mutant cycle scanning of the interaction of a peptide ligand and its G protein-coupled receptor. Biochemistry (2007) 0.83

Changes in conformation at the cytoplasmic ends of the fifth and sixth transmembrane helices of a yeast G protein-coupled receptor in response to ligand binding. Biochemistry (2011) 0.83

Biosynthesis and NMR-studies of a double transmembrane domain from the Y4 receptor, a human GPCR. J Biomol NMR (2008) 0.83

High resolution NMR analysis of the seven transmembrane domains of a heptahelical receptor in organic-aqueous medium. Biopolymers (2002) 0.82

Synthetic peptides as probes for conformational preferences of domains of membrane receptors. Biopolymers (2005) 0.82

Role of extracellular charged amino acids in the yeast alpha-factor receptor. Biochim Biophys Acta (2007) 0.82

Binding of fluorinated phenylalanine alpha-factor analogues to Ste2p: evidence for a cation-pi binding interaction between a peptide ligand and its cognate G protein-coupled receptor. Biochemistry (2010) 0.82

Sexual conjugation in yeast: A paradigm to study G-protein-coupled receptor domain structure. Biopolymers (2004) 0.82

Identification of specific transmembrane residues and ligand-induced interface changes involved in homo-dimer formation of a yeast G protein-coupled receptor. Biochemistry (2009) 0.81

Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies. Biochemistry (2009) 0.81

A solution NMR view of protein dynamics in the biological membrane. Curr Opin Struct Biol (2011) 0.81

NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains. FEBS J (2013) 0.81

Functional fusions of T4 lysozyme in the third intracellular loop of a G protein-coupled receptor identified by a random screening approach in yeast. Protein Eng Des Sel (2012) 0.81

WdChs1p, a class II chitin synthase, is more responsible than WdChs2p (Class I) for normal yeast reproductive growth in the polymorphic, pathogenic fungus Wangiella (Exophiala) dermatitidis. Arch Microbiol (2006) 0.81

Synthesis of peptides containing C-terminal methyl esters using trityl side-chain anchoring: application to the synthesis of a-factor and a-factor analogs. Org Lett (2012) 0.80

NMR observation of HIV-1 gp120 conformational flexibility resulting from V3 truncation. FEBS J (2014) 0.80

Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors. Biochem Biophys Res Commun (2006) 0.80

Expression and biophysical analysis of a triple-transmembrane domain-containing fragment from a yeast G protein-coupled receptor. Biopolymers (2011) 0.80

Incorporation of the unnatural amino acid p-benzoyl-L-phenylalanine (Bpa) into a G protein-coupled receptor in its native context. Adv Exp Med Biol (2009) 0.80

Biosynthesis and biophysical analysis of domains of a yeast G protein-coupled receptor. Biopolymers (2003) 0.79

Biosynthesis of peptide fragments of eukaryotic GPCRs in Escherichia coli by directing expression into inclusion bodies. J Pept Sci (2010) 0.78

Functional expression of the Candida albicans alpha-factor receptor in Saccharomyces cerevisiae. Fungal Genet Biol (2005) 0.78

Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary adenocarcinomas in Syrian golden hamsters contain beta 2-adrenergic receptor single-nucleotide polymorphisms. Genes Chromosomes Cancer (2005) 0.78

Large multiple transmembrane domain fragments of a G protein-coupled receptor: biosynthesis, purification, and biophysical studies. Biopolymers (2012) 0.78

Synthesis and biophysical characterization of a multidomain peptide from a Saccharomyces cerevisiae G protein-coupled receptor. J Biol Chem (2003) 0.78