Published in Mol Biosyst on July 16, 2007
Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion. J Virol (2007) 3.57
Adipocyte metabolism and obesity. J Lipid Res (2008) 1.62
Infectivity of hepatitis C virus is influenced by association with apolipoprotein E isoforms. J Virol (2010) 1.39
GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4. J Lipid Res (2009) 1.33
Protein folding and quality control in the ER. Cold Spring Harb Perspect Biol (2011) 1.33
Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein. Proc Natl Acad Sci U S A (2011) 1.32
Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity. Biochim Biophys Acta (2009) 1.27
Lipids and HCV. Semin Immunopathol (2012) 1.19
Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion. Diabetes (2008) 1.07
Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function. J Clin Invest (2010) 1.06
Nonalcoholic fatty liver disease: a comprehensive review of a growing epidemic. World J Gastroenterol (2014) 1.02
Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) stimulates VLDL assembly through activation of cell death-inducing DFFA-like effector B (CideB). J Biol Chem (2010) 0.95
Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. J Biol Chem (2008) 0.93
Improved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size. J Lipid Res (2009) 0.92
Bile acids specifically increase hepatitis C virus RNA-replication. PLoS One (2012) 0.90
ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice. J Lipid Res (2008) 0.88
Spontaneously diabetic Ins2(+/Akita):apoE-deficient mice exhibit exaggerated hypercholesterolemia and atherosclerosis. Am J Physiol Endocrinol Metab (2011) 0.86
Reducing vascular events risk in patients with dyslipidaemia: an update for clinicians. Ther Adv Chronic Dis (2011) 0.85
The regulation of ApoB metabolism by insulin. Trends Endocrinol Metab (2013) 0.85
A genome-wide association analysis for porcine serum lipid traits reveals the existence of age-specific genetic determinants. BMC Genomics (2014) 0.83
Neutral glycosphingolipids in human blood: a precise mass spectrometry analysis with special reference to lipoprotein-associated Shiga toxin receptors. J Lipid Res (2010) 0.83
Apolipoprotein B-containing lipoprotein assembly in microsomal triglyceride transfer protein-deficient McA-RH7777 cells. J Lipid Res (2010) 0.82
Human luteinized granulosa cells secrete apoB100-containing lipoproteins. J Lipid Res (2010) 0.80
Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice. Toxicol Sci (2014) 0.79
Specific acquisition of functional CD59 but not CD46 or CD55 by hepatitis C virus. PLoS One (2012) 0.78
Very-low-density lipoprotein: complex particles in cardiac energy metabolism. J Lipids (2011) 0.78
Dietary walnut oil modulates liver steatosis in the obese Zucker rat. Eur J Nutr (2013) 0.77
Altered composition of triglyceride-rich lipoproteins and coronary artery disease in a large case-control study. Atherosclerosis (2009) 0.75
Hepatitis C virus G1b infection decreases the number of small low-density lipoprotein particles. World J Gastroenterol (2016) 0.75
Decreased liver triglyceride content in adult rats exposed to protein restriction during gestation and lactation: role of hepatic triglyceride utilization. Clin Exp Pharmacol Physiol (2015) 0.75
Post-weaning increases in the milk-fat globule EGF-factor VIII on fat globules in mouse milk and in the uptake of the fat globules by HC11 mammary epithelial cells. J Biochem (2012) 0.75
CREBH mediates metabolic inflammation to hepatic VLDL overproduction and hyperlipoproteinemia. J Mol Med (Berl) (2017) 0.75
The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet (2004) 9.37
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity. Proc Natl Acad Sci U S A (2002) 6.00
NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol. J Biol Chem (2004) 4.37
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility. Genome Res (2008) 4.33
Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue. Mol Cell Biol (2009) 3.96
Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. PLoS Genet (2010) 3.75
Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. J Clin Invest (2004) 3.23
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet (2008) 2.63
Metabolic syndrome: from epidemiology to systems biology. Nat Rev Genet (2008) 2.49
Txnip balances metabolic and growth signaling via PTEN disulfide reduction. Proc Natl Acad Sci U S A (2008) 2.41
Inferring causal phenotype networks from segregating populations. Genetics (2008) 2.23
BTBR Ob/Ob mutant mice model progressive diabetic nephropathy. J Am Soc Nephrol (2010) 2.16
The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. Traffic (2007) 2.09
Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes. FASEB J (2008) 2.09
Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus. Nat Genet (2006) 1.97
Combined expression trait correlations and expression quantitative trait locus mapping. PLoS Genet (2006) 1.93
The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol (2009) 1.89
The genetic landscape of type 2 diabetes in mice. Endocr Rev (2006) 1.88
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice. Mamm Genome (2009) 1.87
Mice lacking thioredoxin-interacting protein provide evidence linking cellular redox state to appropriate response to nutritional signals. J Biol Chem (2004) 1.66
Dimension reduction for mapping mRNA abundance as quantitative traits. Genetics (2003) 1.63
CAUSAL GRAPHICAL MODELS IN SYSTEMS GENETICS: A UNIFIED FRAMEWORK FOR JOINT INFERENCE OF CAUSAL NETWORK AND GENETIC ARCHITECTURE FOR CORRELATED PHENOTYPES. Ann Appl Stat (2010) 1.62
Gene expression profiles of nondiabetic and diabetic obese mice suggest a role of hepatic lipogenic capacity in diabetes susceptibility. Diabetes (2003) 1.61
Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice. Diabetes (2007) 1.59
Thioredoxin-interacting protein deficiency disrupts the fasting-feeding metabolic transition. J Lipid Res (2004) 1.58
Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex. J Neurosci (2010) 1.58
Genetic and genomic studies of the BTBR ob/ob mouse model of type 2 diabetes. Am J Ther (2005) 1.45
Transgenic expression of cholesterol-7-alpha-hydroxylase prevents atherosclerosis in C57BL/6J mice. Arterioscler Thromb Vasc Biol (2002) 1.39
Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B. Proc Natl Acad Sci U S A (2002) 1.35
Selective phenotyping for increased efficiency in genetic mapping studies. Genetics (2004) 1.34
Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. Am J Physiol Endocrinol Metab (2005) 1.33
Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion. Diabetes (2013) 1.33
SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse. Diabetes (2007) 1.30
Nuclear localization of p38 MAPK in response to DNA damage. Int J Biol Sci (2009) 1.29
Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet. Physiol Genomics (2008) 1.26
FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Mol Endocrinol (2010) 1.23
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. J Biol Chem (2013) 1.20
A role for peroxisome proliferator-activated receptor γ coactivator-1 in the control of mitochondrial dynamics during postnatal cardiac growth. Circ Res (2013) 1.18
A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab (2012) 1.16
Physiological insights gained from gene expression analysis in obesity and diabetes. Annu Rev Nutr (2010) 1.15
The role of blood vessels, endothelial cells, and vascular pericytes in insulin secretion and peripheral insulin action. Endocr Rev (2010) 1.11
Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet. J Lipid Res (2006) 1.10
Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance. Mol Endocrinol (2004) 1.10
Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. PLoS Genet (2011) 1.10
ABCA1 is essential for efficient basolateral cholesterol efflux during the absorption of dietary cholesterol in chickens. J Biol Chem (2003) 1.08
Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation. BMC Genomics (2010) 1.06
Getting biological about the genetics of diabetes. Nat Med (2010) 1.05
Identification of major quantitative trait loci controlling body weight variation in ob/ob mice. Diabetes (2004) 1.04
PGC-1alpha at the crossroads of type 2 diabetes. Nat Genet (2003) 1.04
Contamination with E1A-positive wild-type adenovirus accounts for species-specific stimulation of islet cell proliferation by CCK: a cautionary note. Mol Endocrinol (2010) 1.03
Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER. J Lipid Res (2003) 0.99
Gastrointestinal hormones and the regulation of β-cell mass. Ann N Y Acad Sci (2010) 0.99
Retracted Overexpression of pre-pro-cholecystokinin stimulates beta-cell proliferation in mouse and human islets with retention of islet function. Mol Endocrinol (2008) 0.99
Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets. PLoS Genet (2012) 0.98
A model selection approach for expression quantitative trait loci (eQTL) mapping. Genetics (2010) 0.98
A potent α/β-peptide analogue of GLP-1 with prolonged action in vivo. J Am Chem Soc (2014) 0.96
Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4. Arterioscler Thromb Vasc Biol (2005) 0.95
Abdominal obesity in BTBR male mice is associated with peripheral but not hepatic insulin resistance. Am J Physiol Endocrinol Metab (2006) 0.94
ARP-1/COUP-TF II determines hepatoma phenotype by acting as both a transcriptional repressor of microsomal triglyceride transfer protein and an inducer of CYP7A1. J Biol Chem (2003) 0.94
Coordinate transcriptional repression of liver fatty acid-binding protein and microsomal triglyceride transfer protein blocks hepatic very low density lipoprotein secretion without hepatosteatosis. J Biol Chem (2006) 0.94
Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. J Biol Chem (2008) 0.93
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival. Endocrinology (2010) 0.91
Transgenic expression of CYP7A1 in LDL receptor-deficient mice blocks diet-induced hypercholesterolemia. J Lipid Res (2006) 0.89
The mystery of PCSK9. Arterioscler Thromb Vasc Biol (2004) 0.88
Modeling causality for pairs of phenotypes in system genetics. Genetics (2013) 0.88
Genome scans for transmission ratio distortion regions in mice. Genetics (2012) 0.86
The regulation of ApoB metabolism by insulin. Trends Endocrinol Metab (2013) 0.85
Loss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity. Am J Physiol Endocrinol Metab (2011) 0.84
Protein sorting motifs in the cytoplasmic tail of SorCS1 control generation of Alzheimer's amyloid-β peptide. J Neurosci (2013) 0.84
Neutron-encoded protein quantification by peptide carbamylation. J Am Soc Mass Spectrom (2013) 0.83
Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool. Proc Natl Acad Sci U S A (2008) 0.83
Zinc, insulin, and the liver: a ménage à trois. J Clin Invest (2013) 0.82
Facilitated replacement of Kupffer cells expressing a paraoxonase-1 transgene is essential for ameliorating atherosclerosis in mice. Proc Natl Acad Sci U S A (2005) 0.82
SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells. J Clin Invest (2014) 0.82
Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis. J Lipid Res (2012) 0.81
Microsomal triglyceride transfer protein is essential for hepatic secretion of apoB-100 and apoB-48 but not triglyceride. J Lipid Res (2002) 0.80
Expression of cholesterol-7alpha-hydroxylase in murine macrophages prevents cholesterol loading by acetyl-LDL. J Lipid Res (2002) 0.80
A rapid, microplate SNP genotype assay for the leptinob allele. J Lipid Res (2008) 0.79
Distinguishing covariation from causation in diabetes: a lesson from the protein disulfide isomerase mRNA abundance trait. Diabetes (2004) 0.79
Searching for causality of knocking out Txnip: is Txnip missing in action? Circ Res (2007) 0.78
Quantile-based permutation thresholds for quantitative trait loci hotspots. Genetics (2012) 0.77
How do reducing equivalents increase insulin secretion? J Clin Invest (2015) 0.75
High-maintenance proteins and hypertriglyceridemia. Nat Genet (2007) 0.75
A liver-high-density lipoprotein-ovarian axis of fertility. Endocrinology (2006) 0.75
In memoriam: Roger A. Davis (1945-2008). J Lipid Res (2008) 0.75