Published in Mol Endocrinol on August 23, 2007
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis. Nat Genet (2013) 1.60
Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors. Mol Endocrinol (2008) 1.40
Extracellular signal-regulated kinase mitogen-activated protein kinase signaling initiates a dynamic interplay between sumoylation and ubiquitination to regulate the activity of the transcriptional activator PEA3. Mol Cell Biol (2009) 1.20
Rapid signaling by steroid receptors. Am J Physiol Regul Integr Comp Physiol (2008) 1.18
Steroid receptor phosphorylation: Assigning function to site-specific phosphorylation. Biofactors (2009) 1.13
SUMO-mediated inhibition of glucocorticoid receptor synergistic activity depends on stable assembly at the promoter but not on DAXX. Mol Endocrinol (2008) 1.12
Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression. Breast Cancer Res (2012) 1.08
Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells. Cell Cycle (2013) 1.07
Nuclear receptor coactivators: structural and functional biochemistry. Biochemistry (2010) 1.06
Challenges to defining a role for progesterone in breast cancer. Steroids (2007) 1.04
The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention. Mol Endocrinol (2010) 1.01
Mechanism of BRCA1-mediated inhibition of progesterone receptor transcriptional activity. Mol Endocrinol (2009) 1.00
ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells. Mol Cell Biol (2011) 1.00
Progesterone action in breast, uterine, and ovarian cancers. J Mol Endocrinol (2015) 0.98
Signaling inputs to progesterone receptor gene regulation and promoter selectivity. Mol Cell Endocrinol (2009) 0.98
SUMOylation inhibits SF-1 activity by reducing CDK7-mediated serine 203 phosphorylation. Mol Cell Biol (2008) 0.97
Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells. Proc Natl Acad Sci U S A (2009) 0.97
Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation. BMC Mol Biol (2012) 0.94
Progesterone receptors act as sensors for mitogenic protein kinases in breast cancer models. Endocr Relat Cancer (2009) 0.94
Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis. Am J Pathol (2014) 0.93
Altered retinoid uptake and action contributes to cell survival in endometriosis. J Clin Endocrinol Metab (2010) 0.93
Tip30 deletion in MMTV-Neu mice leads to enhanced EGFR signaling and development of estrogen receptor-positive and progesterone receptor-negative mammary tumors. Cancer Res (2010) 0.92
Molecular determinants of context-dependent progesterone receptor action in breast cancer. BMC Med (2014) 0.92
Progesterone receptor action: defining a role in breast cancer. Expert Rev Endocrinol Metab (2011) 0.92
Controlling a master switch of adipocyte development and insulin sensitivity: covalent modifications of PPARγ. Biochim Biophys Acta (2012) 0.91
Tracking progesterone receptor-mediated actions in breast cancer. Pharmacol Ther (2013) 0.91
Post-Translational Modifications of Kaposi's Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHV. Front Microbiol (2012) 0.89
Progesterone and breast cancer. Womens Health (Lond Engl) (2008) 0.88
Post-translational modifications of the progesterone receptors. J Steroid Biochem Mol Biol (2013) 0.88
Role of phosphorylation in progesterone receptor signaling and specificity. Mol Cell Endocrinol (2011) 0.88
p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization. Mol Endocrinol (2011) 0.88
Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation. J Biol Chem (2009) 0.87
Phosphorylation: a fundamental regulator of steroid receptor action. Trends Endocrinol Metab (2013) 0.86
Progesterone receptor A stability is mediated by glycogen synthase kinase-3β in the Brca1-deficient mammary gland. J Biol Chem (2013) 0.86
Partial agonist activity of the progesterone receptor antagonist RU486 mediated by an amino-terminal domain coactivator and phosphorylation of serine400. Mol Endocrinol (2009) 0.85
A Common Docking Domain in Progesterone Receptor-B links DUSP6 and CK2 signaling to proliferative transcriptional programs in breast cancer cells. Nucleic Acids Res (2013) 0.85
Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. Mol Endocrinol (2014) 0.84
Scaffolding actions of membrane-associated progesterone receptors. Steroids (2008) 0.83
The spindle positioning protein Kar9p interacts with the sumoylation machinery in Saccharomyces cerevisiae. Genetics (2008) 0.82
Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition. Hum Reprod Update (2016) 0.81
Differential regulation of breast cancer-associated genes by progesterone receptor isoforms PRA and PRB in a new bi-inducible breast cancer cell line. PLoS One (2012) 0.80
Acetylation at lysine 183 of progesterone receptor by p300 accelerates DNA binding kinetics and transactivation of direct target genes. J Biol Chem (2013) 0.76
RNPC1 enhances progesterone receptor functions by regulating its mRNA stability in breast cancer. Oncotarget (2017) 0.76
Active FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming. Mol Cancer Res (2015) 0.76
Inflammatory Stimuli Increase Progesterone Receptor-A Stability and Transrepressive Activity in Myometrial Cells. Endocrinology (2016) 0.75
Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs. J Hematol Oncol (2017) 0.75
Tip30 controls differentiation of murine mammary luminal progenitor to estrogen receptor-positive luminal cell through regulating FoxA1 expression. Cell Death Dis (2014) 0.75
Fibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells. Oncotarget (2016) 0.75
The transcriptional repressor GATAD2B mediates progesterone receptor suppression of myometrial contractile gene expression. J Biol Chem (2017) 0.75
Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res (2008) 6.46
Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells. Cancer Res (2007) 1.75
Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells. Mol Cell Biol (2006) 1.64
Phosphorylation of progesterone receptor serine 400 mediates ligand-independent transcriptional activity in response to activation of cyclin-dependent protein kinase 2. Mol Cell Biol (2004) 1.40
Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors. Mol Endocrinol (2008) 1.40
Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors. Mol Endocrinol (2003) 1.31
Regulated association of protein kinase B/Akt with breast tumor kinase. J Biol Chem (2004) 1.25
Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases. Mol Endocrinol (2004) 1.24
Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell (2011) 1.17
Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells. Breast Cancer Res (2010) 1.14
MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association. J Steroid Biochem Mol Biol (2003) 1.11
Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression. Breast Cancer Res (2012) 1.08
Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells. Cell Cycle (2013) 1.07
Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: role of mitogen-activated protein kinases and cell cycle regulators. Steroids (2005) 1.04
Membrane progesterone receptor expression in mammalian tissues: a review of regulation and physiological implications. Steroids (2010) 1.03
Brk/PTK6 signaling in normal and cancer cell models. Curr Opin Pharmacol (2010) 1.02
Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression. Cancer Res (2013) 1.02
The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention. Mol Endocrinol (2010) 1.01
ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells. Mol Cell Biol (2011) 1.00
Mechanisms of HGF/Met signaling to Brk and Sam68 in breast cancer progression. Horm Cancer (2012) 0.99
Decreased recognition of SUMO-sensitive target genes following modification of SF-1 (NR5A1). Mol Cell Biol (2008) 0.98
Signaling inputs to progesterone receptor gene regulation and promoter selectivity. Mol Cell Endocrinol (2009) 0.98
Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells. Proc Natl Acad Sci U S A (2009) 0.97
Progesterone receptors act as sensors for mitogenic protein kinases in breast cancer models. Endocr Relat Cancer (2009) 0.94
Progesterone receptor action: defining a role in breast cancer. Expert Rev Endocrinol Metab (2011) 0.92
PELP1: a review of PELP1 interactions, signaling, and biology. Mol Cell Endocrinol (2013) 0.92
Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK. Breast Cancer Res (2011) 0.90
Role of phosphorylation in progesterone receptor signaling and specificity. Mol Cell Endocrinol (2011) 0.88
Integrated actions of progesterone receptor and cell cycle machinery regulate breast cancer cell proliferation. Steroids (2008) 0.87
Progesterone promotes focal adhesion formation and migration in breast cancer cells through induction of protease-activated receptor-1. J Endocrinol (2012) 0.86
Steadying the boat: integrating mechanisms of membrane and nuclear-steroid-receptor signalling. EMBO Rep (2005) 0.86
Met receptors induce Sam68-dependent cell migration by activation of alternate extracellular signal-regulated kinase family members. J Biol Chem (2011) 0.86
A Common Docking Domain in Progesterone Receptor-B links DUSP6 and CK2 signaling to proliferative transcriptional programs in breast cancer cells. Nucleic Acids Res (2013) 0.85
Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. Mol Endocrinol (2014) 0.84
Scaffolding actions of membrane-associated progesterone receptors. Steroids (2008) 0.83
Cross-talk between growth factor and progesterone receptor signaling pathways: implications for breast cancer cell growth. Breast Dis (2003) 0.81
Expression of membrane progesterone receptors (mPR/PAQR) in ovarian cancer cells: implications for progesterone-induced signaling events. Horm Cancer (2010) 0.80
Dynamic regulation of steroid hormone receptor transcriptional activity by reversible SUMOylation. Vitam Horm (2013) 0.77
2-Methoxyestradiol inhibits progesterone-dependent tissue factor expression and activity in breast cancer cells. Horm Cancer (2010) 0.76
Editorial: membrane and nuclear steroid hormone receptors: two integrated arms of the same signaling pathway? Steroids (2007) 0.76
Progesterone regulation of tissue factor depends on MEK1/2 activation and requires the proline-rich site on progesterone receptor. Endocrine (2014) 0.75
Statement of principle. Endocr Rev (2014) 0.75
Statement of principle. J Clin Endocrinol Metab (2014) 0.75
Meeting review: Extra-nuclear steroid receptors-Integration with multiple signaling pathways. Steroids (2008) 0.75
Statement of principle. Horm Cancer (2015) 0.75
Breast cancer and pregnancy. Obstet Gynecol Clin North Am (2005) 0.75
Lost in translation: can we afford to miss the trees for the forest? Horm Cancer (2014) 0.75