Published in Cancer Res on September 01, 2007
The role of CALM-AF10 gene fusion in acute leukemia. Leukemia (2007) 1.63
Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l. Leukemia (2012) 1.36
Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma. Blood (2012) 0.96
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice. Blood (2009) 0.92
A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis. Blood (2013) 0.90
NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. Cancer Discov (2014) 0.89
Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes. Exp Hematol (2012) 0.86
The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice. Oncogene (2011) 0.86
Murine models of acute leukemia: important tools in current pediatric leukemia research. Front Oncol (2014) 0.84
Nuclear export signal within CALM is necessary for CALM-AF10-induced leukemia. Cancer Sci (2014) 0.79
A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias. Leukemia (2014) 0.79
Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia. Exp Hematol (2013) 0.78
Up a lymphoid blind alley: Does CALM/AF10 disturb Ikaros during leukemogenesis? World J Biol Chem (2011) 0.78
The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models. Leukemia (2015) 0.77
FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia. Blood Cancer J (2011) 0.77
Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation. Leukemia (2014) 0.76
Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect. PLoS One (2012) 0.76
Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance. Genes Chromosomes Cancer (2017) 0.75
CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements. Oncotarget (2016) 0.75
A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy. Oncotarget (2014) 0.75
CATS (FAM64A) abnormal expression reduces clonogenicity of hematopoietic cells. Oncotarget (2016) 0.75
Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science (1999) 83.27
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J (1998) 5.21
Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood (2002) 4.88
Bethesda proposals for classification of lymphoid neoplasms in mice. Blood (2002) 4.07
Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias. Nat Genet (1996) 3.32
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood (2005) 3.09
Chromosome translocations: dangerous liaisons revisited. Nat Rev Cancer (2001) 3.01
Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia. Mol Cell Biol (2001) 2.80
Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia. Mol Cell Biol (1997) 2.61
Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic. Mol Biol Cell (1999) 2.49
The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family. Proc Natl Acad Sci U S A (1996) 2.49
On immunoglobulin heavy chain gene switching: two gamma 2b genes are rearranged via switch sequences in MPC-11 cells but only one is expressed. Nucleic Acids Res (1982) 2.29
Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript. Proc Natl Acad Sci U S A (1989) 2.23
Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment. Blood (1999) 2.06
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia. Blood (2005) 2.03
The SCL gene product: a positive regulator of erythroid differentiation. EMBO J (1992) 1.90
A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors. J Exp Med (1996) 1.86
Hox regulation of normal and leukemic hematopoietic stem cells. Curr Opin Hematol (2005) 1.84
Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression. Mol Cell Biol (2000) 1.79
NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice. EMBO J (2001) 1.78
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell (2006) 1.74
Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Blood (2003) 1.70
The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10. Blood (2002) 1.64
CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes. Leukemia (2005) 1.59
A B220+ CD117+ CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential. Eur J Immunol (2005) 1.51
An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice. EMBO J (1997) 1.43
Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. Mol Cell Biol (2004) 1.43
Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo. Blood (2001) 1.34
The role of NUP98 gene fusions in hematologic malignancy. Leuk Lymphoma (2004) 1.33
Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector. Oncogene (1999) 1.24
The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene. Blood (1995) 1.22
CALM-AF10 is a common fusion transcript in T-ALL and is specific to the TCRgammadelta lineage. Blood (2003) 1.21
Molecular analysis of the CALM/AF10 fusion: identical rearrangements in acute myeloid leukemia, acute lymphoblastic leukemia and malignant lymphoma patients. Leukemia (2000) 1.18
Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice. Proc Natl Acad Sci U S A (2003) 1.04
Identification and molecular characterization of CALM/AF10fusion products in T cell acute lymphoblastic leukemia and acute myeloid leukemia. Leukemia (2000) 1.02
Chromosomal translocation master genes, mouse models and experimental therapeutics. Oncogene (2001) 0.99
HOXA cluster deregulation in T-ALL associated with both a TCRD-HOXA and a CALM-AF10 chromosomal translocation. Leukemia (2006) 0.91
Mixed-lineage leukemia with t(10;11)(p13;q21): an analysis of AF10-CALM and CALM-AF10 fusion mRNAs and clinical features. Genes Chromosomes Cancer (1999) 0.90
Leukemic transformation. Cancer Biol Ther (2004) 0.83
Modelling haematopoietic malignancies in the mouse and therapeutical implications. Oncogene (2002) 0.83
Identification and molecular characterisation of a CALM-AF10 fusion in acute megakaryoblastic leukaemia. Leukemia (2001) 0.80
Loss of Smad3 in acute T-cell lymphoblastic leukemia. N Engl J Med (2004) 2.05
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia. Blood (2005) 2.03
The TLX1 oncogene drives aneuploidy in T cell transformation. Nat Med (2010) 1.93
NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights. Blood (2011) 1.91
Effects of warming and grazing on soil N availability, species composition, and ANPP in an alpine meadow. Ecology (2012) 1.90
Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma. Blood (2005) 1.84
Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Blood (2003) 1.70
Impaired differentiation and apoptosis of hematopoietic precursors in a mouse model of myelodysplastic syndrome. Haematologica (2008) 1.54
Genome architecture marked by retrotransposons modulates predisposition to DNA methylation in cancer. Genome Res (2010) 1.53
Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes. Genes Dev (2010) 1.42
The role of NUP98 gene fusions in hematologic malignancy. Leuk Lymphoma (2004) 1.33
Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation. Cancer Res (2007) 1.30
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood (2009) 1.29
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood (2009) 1.28
Chromosomal rearrangements leading to MLL gene fusions: clinical and biological aspects. Cancer Res (2008) 1.20
Chromosomal aberrations induced by double strand DNA breaks. DNA Repair (Amst) (2005) 1.19
The amino Acid residues at positions 120 to 123 are crucial for the antigenicity of hepatitis B surface antigen. J Clin Microbiol (2007) 1.12
Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl. Blood (2008) 1.12
The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of acute myeloid leukemia in children: an evidence-based review. Biol Blood Marrow Transplant (2007) 1.10
Age-related epigenetic drift in the pathogenesis of MDS and AML. Genome Res (2014) 1.08
Gradient of E2A activity in B-cell development. Mol Cell Biol (2002) 1.07
Chromatin remodeling complex NURF regulates thymocyte maturation. Genes Dev (2011) 1.05
The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr. J Cell Sci (2011) 1.04
Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy. Genes Chromosomes Cancer (2012) 1.02
Characterization of a thermostable β-glucosidase from Aspergillus fumigatus Z5, and its functional expression in Pichia pastoris X33. Microb Cell Fact (2012) 1.00
Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell. Proc Natl Acad Sci U S A (2008) 0.99
Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia. Blood (2013) 0.99
Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma. Blood (2012) 0.96
NUP98-topoisomerase I acute myeloid leukemia-associated fusion gene has potent leukemogenic activities independent of an engineered catalytic site mutation. Blood (2004) 0.94
Cytogenetics and molecular genetics of acute lymphoblastic leukemia. Hematol Oncol Clin North Am (2009) 0.93
NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men. J Natl Cancer Inst Monogr (2008) 0.92
Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice. Blood (2009) 0.92
OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1. Cancer Res (2005) 0.92
Mouse models of myelodysplastic syndromes. Hematol Oncol Clin North Am (2010) 0.90
Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome. Blood (2012) 0.90
A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement. J Immunol (2009) 0.90
NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. Cancer Discov (2014) 0.89
Insertion of MLL sequences into chromosome band 5q31 results in an MLL-AF5Q31 fusion and is a rare but recurrent abnormality associated with infant leukemia. Genes Chromosomes Cancer (2003) 0.89
Efficient repair of DNA double-strand breaks in malignant cells with structural instability. Mutat Res (2010) 0.88
Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model. Blood (2012) 0.88
Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes. Exp Hematol (2012) 0.86
BCL2A1a over-expression in murine hematopoietic stem and progenitor cells decreases apoptosis and results in hematopoietic transformation. PLoS One (2012) 0.86
Growth of catalyst-free high-quality ZnO nanowires by thermal evaporation under air ambient. Nanoscale Res Lett (2012) 0.84
The diphtheria toxin/urokinase fusion protein (DTAT) is selectively toxic to CD87 expressing leukemic cells. Leuk Res (2003) 0.83
Distinct mechanisms lead to HPRT gene mutations in leukemic cells. Genes Chromosomes Cancer (2004) 0.83
Leukemic transformation. Cancer Biol Ther (2004) 0.83
The mitotic checkpoint gene, SIL is regulated by E2F1. Int J Cancer (2008) 0.83
Cloning and characterization of the SIL promoter. Biochim Biophys Acta (2003) 0.83
Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B. Virol J (2013) 0.82
Influence of nitrogen fertilization on diazotrophic communities in the rhizosphere of the Jerusalem artichoke (Helianthus tuberosus L.). Res Microbiol (2012) 0.82
Length and end group dependence of the electronic transport properties in carbon atomic molecular wires. J Chem Phys (2010) 0.81
Compositions, structures, and catalytic activities of CeO₂@Cu₂O nanocomposites prepared by the template-assisted method. Langmuir (2014) 0.80
Genetic interaction between Kit and Scl. Blood (2013) 0.80
15N isotope fractionation in an aquatic food chain: Bellamya aeruginosa (Reeve) as an algal control agent. J Environ Sci (China) (2010) 0.79
Preparation of a novel rape pollen shell microencapsulation and its use for protein adsorption and pH-controlled release. J Microencapsul (2014) 0.79
Controllably interfacing with metal: a strategy for enhancing CO oxidation on oxide catalysts by surface polarization. J Am Chem Soc (2014) 0.78
Isolated Hoxa9 overexpression predisposes to the development of lymphoid but not myeloid leukemia. Exp Hematol (2013) 0.78
Enforced expression of Simian virus 40 large T-antigen leads to testicular germ cell tumors in zebrafish. Zebrafish (2010) 0.78
Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis. Proc Natl Acad Sci U S A (2003) 0.78
Molecular cloning, mRNA expression, and characterization of HSP90 gene from Chinese mitten crab Eriocheir japonica sinensis. Comp Biochem Physiol B Biochem Mol Biol (2009) 0.78
Measuring period of human biological clock: infill asymptotic analysis of harmonic regression parameter estimates. Methods Enzymol (2004) 0.77
p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis. Blood (2007) 0.77
An optimized DNA extraction and purification method from dairy manure compost for genetic diversity analysis. World J Microbiol Biotechnol (2012) 0.76
Effect of FLT3 ligand on survival and disease phenotype in murine models harboring a FLT3 internal tandem duplication mutation. Comp Med (2013) 0.76
Notching up MYC gives a LIC. Cell Stem Cell (2013) 0.76
The fusion partner specifies the oncogenic potential of NUP98 fusion proteins. Leuk Res (2013) 0.76
Assembly of fused indenes via Au(I)-catalyzed C1-C5 cyclization of enediynes bearing an internal nucleophile. Chem Commun (Camb) (2013) 0.76
Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect. PLoS One (2012) 0.76
A robust in vivo model for B cell precursor acute lymphoblastic leukemia. J Clin Invest (2015) 0.75
Cre-loxP-mediated recombination between the SIL and SCL genes leads to a block in T-cell development at the CD4- CD8- to CD4+ CD8+ transition. Neoplasia (2007) 0.75
Methane emission by plant communities in an alpine meadow on the Qinghai-Tibetan Plateau: a new experimental study of alpine meadows and oat pasture. Biol Lett (2009) 0.75
Corrigendum: Contrasting effects of nitrogen and phosphorus addition on soil respiration in an alpine grassland on the Qinghai-Tibetan Plateau. Sci Rep (2017) 0.75
The clinical outcome of the endoscopic submucosal dissection of colonic polyps larger than 20 mm. A single medical study. Ann Ital Chir (2021) 0.75
Atomic H-Induced Mo2C Hybrid as an Active and Stable Bifunctional Electrocatalyst. ACS Nano (2016) 0.75
Modifying Surface Chemistry of Metal Oxides for Boosting Dissolution Kinetics in Water by Liquid Cell Electron Microscopy. ACS Nano (2017) 0.75
Identification, mRNA expression and characterization of a novel ANK-like gene from Chinese mitten crab Eriocheir japonica sinensis. Comp Biochem Physiol B Biochem Mol Biol (2009) 0.75
Assessment of the maturity and biological parameters of compost produced from dairy manure and rice chaff by excitation-emission matrix fluorescence spectroscopy. Bioresour Technol (2012) 0.75
[Using chlorella and effective microorganisms to optimize aquatic ecological structure and to regulate water quality]. Ying Yong Sheng Tai Xue Bao (2003) 0.75
Efficient Removal of Methane over the Cobalt Monoxide Doped AuPd Nanocatalysts. Environ Sci Technol (2017) 0.75
Ocean mixed layer depth estimation using airborne Brillouin scattering lidar: simulation and model. Appl Opt (2021) 0.75