|
1
|
Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity.
|
Circ Res
|
2007
|
4.92
|
|
2
|
Pyogenic bacterial infections in humans with IRAK-4 deficiency.
|
Science
|
2003
|
4.80
|
|
3
|
The influence of host and bacterial genotype on the development of disseminated disease with Mycobacterium tuberculosis.
|
PLoS Pathog
|
2008
|
3.79
|
|
4
|
The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans.
|
Cell
|
2010
|
3.64
|
|
5
|
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.
|
Cell
|
2012
|
3.54
|
|
6
|
Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling.
|
J Immunol
|
2003
|
2.02
|
|
7
|
Toll-like receptor polymorphisms and susceptibility to human disease.
|
Clin Sci (Lond)
|
2008
|
1.94
|
|
8
|
Mycobacterium tuberculosis, macrophages, and the innate immune response: does common variation matter?
|
Immunol Rev
|
2007
|
1.88
|
|
9
|
Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection.
|
J Immunol
|
2007
|
1.57
|
|
10
|
Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction.
|
PLoS Negl Trop Dis
|
2008
|
1.56
|
|
11
|
Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles.
|
PLoS Pathog
|
2008
|
1.41
|
|
12
|
Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy.
|
J Infect Dis
|
2008
|
1.34
|
|
13
|
Leprosy and the human genome.
|
Microbiol Mol Biol Rev
|
2010
|
1.27
|
|
14
|
Differential constitutive and cytokine-modulated expression of human Toll-like receptors in primary neutrophils, monocytes, and macrophages.
|
Int J Med Sci
|
2008
|
1.24
|
|
15
|
Human TOLLIP regulates TLR2 and TLR4 signaling and its polymorphisms are associated with susceptibility to tuberculosis.
|
J Immunol
|
2012
|
1.21
|
|
16
|
Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.
|
PLoS Pathog
|
2011
|
1.13
|
|
17
|
Towards subtlety: understanding the role of Toll-like receptor signaling in susceptibility to human infections.
|
Clin Immunol
|
2006
|
1.12
|
|
18
|
Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens.
|
Infect Immun
|
2003
|
1.11
|
|
19
|
Genetic variants associated with susceptibility to Helicobacter pylori.
|
JAMA
|
2013
|
1.11
|
|
20
|
Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes.
|
Hum Immunol
|
2010
|
1.09
|
|
21
|
NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila.
|
Eur J Immunol
|
2010
|
1.09
|
|
22
|
The dynamics of QuantiFERON-TB gold in-tube conversion and reversion in a cohort of South African adolescents.
|
Am J Respir Crit Care Med
|
2015
|
1.08
|
|
23
|
Role of Toll-like receptor 5 in the innate immune response to acute P. aeruginosa pneumonia.
|
Am J Physiol Lung Cell Mol Physiol
|
2009
|
1.07
|
|
24
|
Impaired TLR5 functionality is associated with survival in melioidosis.
|
J Immunol
|
2013
|
0.96
|
|
25
|
Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam.
|
J Infect Dis
|
2005
|
0.96
|
|
26
|
Toll-like receptor signaling in airborne Burkholderia thailandensis infection.
|
Infect Immun
|
2009
|
0.96
|
|
27
|
Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene region are associated with susceptibility to tuberculosis.
|
J Infect Dis
|
2012
|
0.94
|
|
28
|
Tuberculosis Infection: Insight from Immunogenomics.
|
Drug Discov Today Dis Mech
|
2007
|
0.92
|
|
29
|
Family history and risk of recurrent cystitis and pyelonephritis in women.
|
J Urol
|
2010
|
0.92
|
|
30
|
Human CD1a deficiency is common and genetically regulated.
|
J Immunol
|
2013
|
0.92
|
|
31
|
The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury.
|
PLoS One
|
2009
|
0.90
|
|
32
|
Maturation of innate responses to mycobacteria over the first nine months of life.
|
J Immunol
|
2014
|
0.85
|
|
33
|
Toll-like receptors: their roles in bacterial recognition and respiratory infections.
|
Expert Rev Anti Infect Ther
|
2008
|
0.82
|
|
34
|
Common polymorphisms in the CD43 gene region are associated with tuberculosis disease and mortality.
|
Am J Respir Cell Mol Biol
|
2015
|
0.79
|
|
35
|
Toll-like receptor polymorphisms are associated with increased neurosyphilis risk.
|
Sex Transm Dis
|
2014
|
0.78
|
|
36
|
Toll-like receptor stimulation induces higher TNF-alpha secretion in peripheral blood mononuclear cells from patients with hyper IgE syndrome.
|
Int Arch Allergy Immunol
|
2008
|
0.78
|
|
37
|
Nucleotide-binding oligomerization domain containing-like receptor family, caspase recruitment domain (CARD) containing 4 (NLRC4) regulates intrapulmonary replication of aerosolized Legionella pneumophila.
|
BMC Infect Dis
|
2013
|
0.77
|
|
38
|
Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data.
|
PLoS One
|
2012
|
0.76
|
|
39
|
Role of oral antibiotics in treatment of breastfeeding women with chronic breast pain who fail conservative therapy.
|
Breastfeed Med
|
2014
|
0.75
|
|
40
|
Human susceptibility to legionnaires' disease.
|
Methods Mol Biol
|
2013
|
0.75
|