Published in Org Lett on September 15, 2007
Stereoselective synthesis of gamma-substituted (Z)-allylic boranes via kinetically controlled hydroboration of allenes with 10-TMS-9-borabicyclo[3.3.2]decane. J Am Chem Soc (2009) 1.41
Diastereo- and enantioselective anti-alkoxyallylation employing allylic gem-dicarboxylates as allyl donors via iridium-catalyzed transfer hydrogenation. J Am Chem Soc (2010) 1.25
Iridium-catalyzed anti-diastereo- and enantioselective carbonyl (trimethylsilyl)allylation from the alcohol or aldehyde oxidation level. J Am Chem Soc (2010) 1.23
Enantio- and diastereoselective synthesis of (E)-1,5-syn-diols: application to the synthesis of the C(23)-C(40) fragment of tetrafibricin. Org Lett (2011) 0.99
Enantioselective syntheses of syn- and anti-β-hydroxyallylsilanes via allene hydroboration-aldehyde allylboration reactions. Org Lett (2011) 0.93
Development of a Double Allylboration Reagent Targeting 1,5-syn-(E)-Diols: Application to the Synthesis of the C(23)-C(40) Fragment of Tetrafibricin. Tetrahedron (2011) 0.88
Diisopinocampheylborane-mediated reductive aldol reactions: highly enantio- and diastereoselective synthesis of syn aldols from N-acryloylmorpholine. Angew Chem Int Ed Engl (2013) 0.83
(Diisopinocampheyl)borane-mediated reductive aldol reactions of acrylate esters: enantioselective synthesis of anti-aldols. Org Lett (2013) 0.78
Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature (2011) 4.19
Enantioselective synthesis of 1,5-anti- and 1,5-syn-diols using a highly diastereoselective one-pot double allylboration reaction sequence. J Am Chem Soc (2002) 2.31
Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis. Cancer Res (2013) 1.46
The vinylogous intramolecular Morita-Baylis-Hillman reaction: synthesis of functionalized cyclopentenes and cyclohexenes with trialkylphosphines as nucleophilic catalysts. J Am Chem Soc (2002) 1.44
Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences. J Am Chem Soc (2009) 1.41
Stereoselective synthesis of gamma-substituted (Z)-allylic boranes via kinetically controlled hydroboration of allenes with 10-TMS-9-borabicyclo[3.3.2]decane. J Am Chem Soc (2009) 1.41
Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones. Antimicrob Agents Chemother (2003) 1.39
Efficient protiodesilylation of unactivated C(sp3)-SiMe2Ph bonds using tetrabutylammonium fluoride. Org Lett (2005) 1.35
Synthesis of the C(1)-C(25) fragment of amphidinol 3: application of the double-allylboration reaction for synthesis of 1,5-diols. Org Lett (2005) 1.34
Enantioselective synthesis of (E)-delta-stannyl homoallylic alcohols via aldehyde allylboration using alpha-stannylallylboranes generated by allene hydroboration followed by a highly diastereoselective 1,3-boratropic shift. J Am Chem Soc (2010) 1.27
A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. ACS Chem Biol (2010) 1.26
Synthesis of the C(43)-C(67) fragment of amphidinol 3. Org Lett (2005) 1.26
Stereoselective synthesis of the C(1)-C(11) fragment of peloruside A. Org Lett (2005) 1.24
Synthesis of the C11-C29 fragment of amphidinolide F. Org Lett (2004) 1.24
Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist. ACS Chem Biol (2010) 1.22
Stereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin. Org Lett (2007) 1.20
The origin of diastereofacial control in allylboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen. J Am Chem Soc (2002) 1.17
Total synthesis of (-)-spinosyn A. Proc Natl Acad Sci U S A (2004) 1.16
Relative rates of Michael reactions of 2'-(phenethyl)thiol with vinyl sulfones, vinyl sulfonate esters, and vinyl sulfonamides relevant to vinyl sulfonyl cysteine protease inhibitors. Org Lett (2003) 1.14
Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ. ACS Chem Biol (2010) 1.14
Origin of thermodynamic versus kinetic control of allene hydroboration with 9-borabicyclo[3.3.1]nonane and 10(R)-trimethylsilyl-9-borabicyclo[3.3.2]decane. Org Lett (2009) 1.13
Stereoselective synthesis of a model C(18)-C(35) spiroketal fragment of integramycin. Org Lett (2011) 1.13
Total synthesis of (+)-superstolide A. J Org Chem (2008) 1.09
Thermodynamic control of 1,3-boratropic shifts of α- and γ-stannyl-substituted allylboranes: hyperconjugation outweighs steric effects. Org Lett (2011) 1.08
Total synthesis of (-)-bafilomycin A(1). J Am Chem Soc (2002) 1.08
Enantioconvergent hydroboration of a racemic allene: enantioselective synthesis of (E)-δ-stannyl-anti-homoallylic alcohols via aldehyde crotylboration. J Am Chem Soc (2011) 1.08
Use of recombinant Entamoeba histolytica cysteine proteinase 1 to identify a potent inhibitor of amebic invasion in a human colonic model. Eukaryot Cell (2007) 1.07
Recent advances in the synthesis, design and selection of cysteine protease inhibitors. Curr Opin Chem Biol (2002) 1.05
Application of the intramolecular vinylogous Morita-Baylis-Hillman reaction toward the synthesis of the spinosyn A tricyclic nucleus. Org Lett (2002) 1.05
Synthesis of (+)-bullatacin via the highly diastereoselective [3+2] annulation reaction of a racemic aldehyde and a nonracemic allylsilane. Org Lett (2005) 1.04
Enantioselective synthesis of (-)-basiliskamide A. Org Lett (2012) 1.04
Synthesis of 2,6-trans-disubstituted 5,6-dihydropyrans from (Z)-1,5-syn-endiols. Beilstein J Org Chem (2005) 1.03
A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target. J Biol Chem (2010) 1.03
Total synthesis of +-superstolide A. J Am Chem Soc (2008) 1.02
Total synthesis of asimicin via highly stereoselective [3 + 2] annulation reactions of substituted allylsilanes. J Am Chem Soc (2005) 1.02
Total synthesis of (-)-tirandamycin C. Org Lett (2011) 1.01
Stereoselective synthesis of 2-deoxy-beta-galactosides via 2-deoxy-2-bromo- and 2-deoxy-2-iodo-galactopyranosyl donors. Org Lett (2003) 1.00
Diastereoselective synthesis of the C(17)-C(28) fragment (the C-D spiroketal unit) of spongistatin 1 (altohyrtin A) via a kinetically controlled iodo-spiroketalization reaction. Org Lett (2002) 1.00
Enantio- and diastereoselective synthesis of (E)-1,5-syn-diols: application to the synthesis of the C(23)-C(40) fragment of tetrafibricin. Org Lett (2011) 0.99
Synthesis of the A-B subunit of angelmicin B. Org Lett (2005) 0.99
Stereoselective syntheses of the C(1)-C(9) fragment of amphidinolide C. Org Lett (2008) 0.98
Total Synthesis of Amphidinolide E and Amphidinolide E Stereoisomers. Tetrahedron (2007) 0.98
Total synthesis of (-)-spinosyn A: examination of structural features that govern the stereoselectivity of the key transannular Diels-Alder reaction. J Org Chem (2008) 0.98
Total synthesis of (+)-13-deoxytedanolide. J Am Chem Soc (2005) 0.96
Highly stereoselective synthesis of anti,anti-dipropionate stereotriads: a solution to the long-standing problem of challenging mismatched double asymmetric crotylboration reactions. J Am Chem Soc (2012) 0.96
Stereoselective synthesis of syn,syn- and syn,anti-1,3,5-triols via intramolecular hydrosilylation of substituted pent-3-en-1,5-diols. Org Lett (2009) 0.96
Studies on the Synthesis of Reidispongiolide A: Stereoselective Synthesis of the C(22)-C(36) Fragment. Tetrahedron (2011) 0.96
Stereoselective synthesis of the octahydronaphthalene unit of integramycin via an intramolecular Diels-Alder reaction. Org Lett (2005) 0.96
Quantum-mechanical study of 10-R-9-borabicyclo[3.3.2]decane alkene hydroboration. J Org Chem (2009) 0.96
Synthesis of precursors of the agalacto (exo) fragment of the quartromicins via an auxiliary-controlled exo-selective Diels-Alder reaction. Org Lett (2006) 0.96
Synthesis of the C(21)-C(26) fragment of superstolide A: concerning the stereochemistry of (E)-crotylboration reactions of alaninal derivatives. J Org Chem (2003) 0.95
Synthesis of the C(26)-C(42) and C(43)-C(67) pyran-containing fragments of amphidinol 3 via a common pyran intermediate. Org Lett (2008) 0.95
[3 + 2]-annulation reactions of chiral allylsilanes and chiral aldehydes. studies on the synthesis of bis-tetrahydrofuran substructures of annonaceous acetogenins. J Org Chem (2005) 0.95
Total synthesis of amphidinolide E. J Am Chem Soc (2006) 0.94
Identification of novel, exosite-binding matrix metalloproteinase-13 inhibitor scaffolds. Bioorg Med Chem Lett (2011) 0.94
Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties. Bioorg Med Chem Lett (2013) 0.93
Studies on the synthesis of apoptolidin A. 2. Synthesis of the disaccharide unit. J Org Chem (2007) 0.93
Total syntheses of (+)-tedanolide and (+)-13-deoxytedanolide. J Am Chem Soc (2008) 0.93
Synthetic studies toward FR182877. Remarkable solvent effect in the vinylogous morita-baylis-hillman cyclization. Org Lett (2003) 0.93
Enantioselective syntheses of syn- and anti-β-hydroxyallylsilanes via allene hydroboration-aldehyde allylboration reactions. Org Lett (2011) 0.93
In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. PLoS Negl Trop Dis (2010) 0.93
Enantioselective synthesis of (+)-crocacin C. An example of a highly challenging mismatched double asymmetric δ-stannylcrotylboration reaction. Org Lett (2012) 0.93
Small-molecule inhibitors of acetyltransferase p300 identified by high-throughput screening are potent anticancer agents. Mol Cancer Ther (2013) 0.92
Studies on the synthesis of quartromicins a(3) and d(3): synthesis of the vertical and horizontal bis-spirotetronate fragments. J Org Chem (2006) 0.92
2-Deoxy-2-iodo-beta-glucopyranosyl fluorides: mild and highly stereoselective glycosyl donors for the synthesis of 2-deoxy-beta-glycosides from beta-hydroxy ketones. Org Lett (2003) 0.92
Studies toward the total synthesis of angelmicin B (hibarimicin B): synthesis of a model CD-D' arylnaphthoquinone. Org Lett (2004) 0.91
Concerning the origin of the high beta-selectivity of glycosidation reactions of 2-deoxy-2-iodo-glucopyranosyl trichloroacetimidates. Org Lett (2002) 0.91
Highly stereoselective and modular syntheses of 10-hydroxytrilobacin and three diastereomers via stereodivergent [3 + 2]-annulation reactions. Org Lett (2008) 0.91
Stereoselective Synthesis of the Decahydrofluorene Core of the Hirsutellones. Tetrahedron Lett (2011) 0.91
Remarkable phosphine-effect on the intramolecular aldol reactions of unsaturated 1,5-diketones: highly regioselective synthesis of cross-conjugated dienones. J Am Chem Soc (2005) 0.91
Synthesis and structure-activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors. J Med Chem (2014) 0.90
Concerning the selective protection of (Z)-1,5-syn-ene-diols and (E)-1,5-anti-ene-diols as allylic triethylsilyl ethers. Org Lett (2007) 0.90
Studies on the synthesis of (-)-spinosyn a: application of the steric directing group strategy to transannular Diels-Alder reactions. J Org Chem (2002) 0.90
Rational development of 4-aminopyridyl-based inhibitors targeting Trypanosoma cruzi CYP51 as anti-chagas agents. J Med Chem (2013) 0.89
Studies on the synthesis of apoptolidin A. 1. Synthesis of the C(1)-C(11) fragment. J Org Chem (2007) 0.89
Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds. Bioorg Med Chem Lett (2008) 0.89
Alkyldimethylpyrazines in the defensive spray of Phyllium westwoodii: a first for order Phasmatodea. J Chem Ecol (2009) 0.89
Studies on the synthesis of durhamycin A: stereoselective synthesis of a model aglycone. Org Lett (2008) 0.89
Intramolecular Diels-Alder reactions of siloxacyclopentene constrained trienes. Org Lett (2007) 0.88
Development of a Double Allylboration Reagent Targeting 1,5-syn-(E)-Diols: Application to the Synthesis of the C(23)-C(40) Fragment of Tetrafibricin. Tetrahedron (2011) 0.88
4-Aminopyridyl-based CYP51 inhibitors as anti-Trypanosoma cruzi drug leads with improved pharmacokinetic profile and in vivo potency. J Med Chem (2014) 0.88
An ultra-high throughput cell-based screen for wee1 degradation inhibitors. J Biomol Screen (2010) 0.87
Total synthesis of cochleamycin A. Org Lett (2004) 0.87
Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptors. ACS Chem Biol (2011) 0.87
Crotylboron-based synthesis of the polypropionate units of chaxamycins A/D, salinisporamycin, and rifamycin S. J Org Chem (2012) 0.85
Chemistry and biology of macrolide antiparasitic agents. J Med Chem (2011) 0.85
Applications of chiral allylmetallating agents toward the synthesis of oxygen heterocyles. Curr Opin Drug Discov Devel (2008) 0.85
Highly (E)-selective BF(3).Et(2)O-promoted allylboration of chiral nonracemic alpha-substituted allylboronates and analysis of the origin of stereocontrol. Org Lett (2010) 0.85
Synthesis of macrocyclic trypanosomal cysteine protease inhibitors. Bioorg Med Chem Lett (2008) 0.85
Enantio- and diastereoselective synthesis of cyclic beta-hydroxy allylsilanes via sequential aldehyde gamma-silylallylboration and ring-closing metathesis reactions. Org Lett (2003) 0.85
Diisopinocampheylborane-mediated reductive aldol reactions: highly enantio- and diastereoselective synthesis of syn aldols from N-acryloylmorpholine. Angew Chem Int Ed Engl (2013) 0.83
Stereoselective synthesis of functionalized precursors of the CDEF and CDE 2,6-dideoxy-tetra- and trisaccharide units of durhamycins A and B. Org Lett (2003) 0.82
Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. J Med Chem (2014) 0.82
Enantioselective synthesis of (Z)-1,2-anti-2,5-anti-triol monosilyl ethers using a cross-metathesis allylboration sequence. Org Lett (2010) 0.82
Chiral Brønsted acid catalyzed enantioselective synthesis of anti-homopropargyl alcohols via kinetic resolution-aldehyde allenylboration using racemic allenylboronates. Org Lett (2013) 0.81
Common-intermediate strategy for synthesis of conduritols and inositols via beta-hydroxy cyclohexenylsilanes. Org Lett (2003) 0.81
Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. Antiviral Res (2011) 0.81