Published in J Mol Med (Berl) on September 18, 2007
Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism. Proc Natl Acad Sci U S A (2010) 2.46
Indoleamine 2,3-dioxygenase specific, cytotoxic T cells as immune regulators. Blood (2010) 2.01
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors. Clin Cancer Res (2014) 1.73
The Synergistic Local Immunosuppressive Effects of Neural Stem Cells Expressing Indoleamine 2,3-Dioxygenase (IDO) in an Experimental Autoimmune Encephalomyelitis (EAE) Animal Model. PLoS One (2015) 1.39
Regulatory dendritic cells: there is more than just immune activation. Front Immunol (2012) 1.25
Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children. Sci Rep (2016) 1.10
Dendritic cells in chronic mycobacterial granulomas restrict local anti-bacterial T cell response in a murine model. PLoS One (2010) 1.08
Immune response to Mycobacterium tuberculosis and identification of molecular markers of disease. Am J Respir Cell Mol Biol (2008) 1.08
The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase. PLoS One (2009) 1.07
CD40-activated B cells can be generated in high number and purity in cancer patients: analysis of immunogenicity and homing potential. Clin Exp Immunol (2008) 1.05
Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase. PLoS One (2012) 1.02
Mycobacterium leprae-host-cell interactions and genetic determinants in leprosy: an overview. Future Microbiol (2011) 1.00
The role of indoleamine 2, 3-dioxygenase in lepromatous leprosy immunosuppression. Clin Exp Immunol (2011) 0.92
New Insights into IDO Biology in Bacterial and Viral Infections. Front Immunol (2014) 0.92
Potential biofluid markers and treatment targets for renal cell carcinoma. Nat Rev Urol (2013) 0.91
Adenosine and cAMP signalling skew human dendritic cell differentiation towards a tolerogenic phenotype with defective CD8(+) T-cell priming capacity. Immunology (2013) 0.87
Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection. PLoS One (2012) 0.85
The specific targeting of immune regulation: T-cell responses against Indoleamine 2,3-dioxygenase. Cancer Immunol Immunother (2012) 0.84
Peripheral regulatory cells immunophenotyping in kidney transplant recipients with different clinical profiles: a cross-sectional study. J Transplant (2012) 0.82
Haemophilus ducreyi lipooligosaccharides induce expression of the immunosuppressive enzyme indoleamine 2,3-dioxygenase via type I interferons and tumor necrosis factor alpha in human dendritic cells. Infect Immun (2011) 0.81
Localization of indoleamine 2,3-dioxygenase in human esophageal squamous cell carcinomas. Virchows Arch (2009) 0.80
Indoleamine 2,3-dioxygenase: expressing cells in inflammatory bowel disease-a cross-sectional study. Clin Dev Immunol (2013) 0.79
Direct T cell-tumour interaction triggers TH1 phenotype activation through the modification of the mesenchymal stromal cells transcriptional programme. Br J Cancer (2014) 0.78
Indoleamine 2,3-dioxygenase: As a potential prognostic marker and immunotherapeutic target for hepatocellular carcinoma. World J Gastroenterol (2017) 0.75
Cytokines and Effector/Regulatory Cells Characterization in the Physiopathology of Cutaneous Lupus Erythematous: A Cross-Sectional Study. Mediators Inflamm (2016) 0.75
Expression of indoleamine 2,3-dioxygenase in a murine model of Aspergillus fumigatus keratitis. Int J Ophthalmol (2016) 0.75
Aspects of Tryptophan and Nicotinamide Adenine Dinucleotide in Immunity: A New Twist in an Old Tale. Int J Tryptophan Res (2017) 0.75
The IDO-AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection. Front Immunol (2017) 0.75
Regulatory T cells in cancer. Blood (2006) 3.56
Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell (2006) 2.87
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood (2005) 2.81
Intrahepatic IL-8 producing Foxp3⁺CD4⁺ regulatory T cells and fibrogenesis in chronic hepatitis C. J Hepatol (2013) 2.03
In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma. Blood (2006) 1.92
FOXO-dependent regulation of innate immune homeostasis. Nature (2010) 1.89
IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res (2011) 1.59
Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. J Clin Invest (2006) 1.58
A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials. Genomics (2006) 1.51
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol (2011) 1.49
High-resolution transcriptome of human macrophages. PLoS One (2012) 1.42
Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin Cancer Res (2004) 1.42
Dendritic cells are significantly reduced in non-Hodgkin's lymphoma and express less CCR7 and CD62L. Leuk Lymphoma (2006) 1.39
Elevated serum levels of CC thymus and activation-related chemokine (TARC) in primary Hodgkin's disease: potential for a prognostic factor. Cancer Res (2005) 1.32
miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood (2009) 1.25
Regulatory dendritic cells: there is more than just immune activation. Front Immunol (2012) 1.25
CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. Cancer Res (2013) 1.22
Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin. Immunity (2007) 1.21
Global transcriptional profiles of beating clusters derived from human induced pluripotent stem cells and embryonic stem cells are highly similar. BMC Dev Biol (2010) 1.21
Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18. J Cell Sci (2012) 1.18
CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. Blood (2005) 1.17
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. Cancer Res (2012) 1.16
Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma. Cancer Res (2006) 1.15
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. Proc Natl Acad Sci U S A (2003) 1.14
RNA fingerprints provide direct evidence for the inhibitory role of TGFbeta and PD-1 on CD4+ T cells in Hodgkin lymphoma. Blood (2007) 1.13
O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells. Eur J Immunol (2003) 1.12
Blood-based gene expression signatures in non-small cell lung cancer. Clin Cancer Res (2011) 1.09
HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy. J Immunol (2002) 1.06
Autoantibodies frequently detected in patients with aplastic anemia. Blood (2003) 1.05
Regulatory T cells: major players in the tumor microenvironment. Curr Pharm Des (2009) 1.02
Unique transcriptome signature of mouse microglia. Glia (2013) 1.00
Bead array-based microrna expression profiling of peripheral blood and the impact of different RNA isolation approaches. J Mol Diagn (2010) 0.98
Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma. Br J Haematol (2003) 0.96
Blood-based transcriptomics: leukemias and beyond. Expert Rev Mol Diagn (2009) 0.95
RNA stabilization of peripheral blood and profiling by bead chip analysis. Methods Mol Biol (2009) 0.94
The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells. Blood (2003) 0.94
Correspondence re R. Lapointe et al., CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 2003;63:2836-43. Cancer Res (2004) 0.93
In vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration. PLoS One (2012) 0.92
CASPAR: a hierarchical bayesian approach to predict survival times in cancer from gene expression data. Bioinformatics (2006) 0.91
Human resting CD4+ T cells are constitutively inhibited by TGF beta under steady-state conditions. J Immunol (2007) 0.91
Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms. J Immunol (2008) 0.90
Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity. Cell Rep (2013) 0.90
Use of genome-wide high-throughput technologies in biomarker development. Biomark Med (2008) 0.89
Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis. EMBO J (2011) 0.89
RNA-stabilized whole blood samples but not peripheral blood mononuclear cells can be stored for prolonged time periods prior to transcriptome analysis. J Mol Diagn (2011) 0.88
CD25 as an immune regulatory molecule expressed on myeloid dendritic cells. Immunobiology (2008) 0.88
Immunoregulatory T cells: role and potential as a target in malignancy. Curr Oncol Rep (2008) 0.88
Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination. Int J Cancer (2007) 0.86
The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells. Cancer Res (2009) 0.86
Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection. PLoS One (2012) 0.85
Plasticity of T(reg) cells: is reprogramming of T(reg) cells possible in the presence of FOXP3? Int Immunopharmacol (2010) 0.85
Application of T cell-based transcriptomics to identify three candidate biomarkers for monitoring anti-TGFbetaR therapy. Pharmacogenet Genomics (2010) 0.85
Comparative approach to define increased regulatory T cells in different cancer subtypes by combined assessment of CD127 and FOXP3. Clin Dev Immunol (2011) 0.85
X-linked dystonia parkinsonism syndrome (XDP, lubag): disease-specific sequence change DSC3 in TAF1/DYT3 affects genes in vesicular transport and dopamine metabolism. Hum Mol Genet (2012) 0.84
Generation of melanoma-specific cytotoxic T lymphocytes for allogeneic immunotherapy. J Immunother (2003) 0.84
CD4+CD25highFOXP3+ regulatory T cells in peripheral blood are primarily of effector memory phenotype. J Clin Oncol (2007) 0.83
The IDO1-induced kynurenines play a major role in the antimicrobial effect of human myeloid cells against Listeria monocytogenes. Innate Immun (2013) 0.83
Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy". Cancer Res (2009) 0.82
The development of a comparison approach for Illumina bead chips unravels unexpected challenges applying newest generation microarrays. BMC Bioinformatics (2009) 0.82
Identification of a new HLA-A*0201-restricted cryptic epitope from CYP1B1. Int J Cancer (2005) 0.81
Prediction and prognosis: impact of gene expression profiling in personalized treatment of breast cancer patients. EPMA J (2010) 0.81
The Connexin40A96S mutation from a patient with atrial fibrillation causes decreased atrial conduction velocities and sustained episodes of induced atrial fibrillation in mice. J Mol Cell Cardiol (2013) 0.81
Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clin Cancer Res (2008) 0.81
Vav1 regulates MHCII expression in murine resting and activated B cells. Int Immunol (2013) 0.80
From genomics to cancer vaccines: patient-tailored or universal vaccines? Curr Opin Mol Ther (2002) 0.80
Efficient activation of autologous tumor-specific T cells: a simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma. J Immunother (2007) 0.79
Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging. BMC Genomics (2013) 0.79
NK cell depletion diminish tumour-specific B cell responses. Immunol Lett (2004) 0.78
T cell responses to hepatitis B surface antigen are detectable in non-vaccinated individuals. World J Gastroenterol (2008) 0.78
Expression of a neuroendocrine gene signature in gastric tumor cells from CEA 424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. PLoS One (2012) 0.78
Degeneracy instead of specificity: is this a solution to cancer immunotherapy? Trends Immunol (2002) 0.77
T-cell analysis in identical twins reveals an impaired anti-follicular lymphoma immune response in the patient but not in the healthy twin. Br J Haematol (2002) 0.77
Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies. Clin Cancer Res (2005) 0.77
Cytokine-dependent regulation of dendritic cell differentiation in the splenic microenvironment. Eur J Immunol (2013) 0.77
Re-overcoming barriers in translating biomarkers to clinical practice. Expert Opin Med Diagn (2010) 0.76
Using CD40-activated B cells to efficiently identify epitopes of tumor antigens. J Immunother (2009) 0.76
The major subtypes of human B-cell lymphomas lack mutations in BCL-2 family member BAD. Int J Cancer (2006) 0.75
Imbalance of DNA-dependent protein kinase subunits in polycythemia vera peripheral blood stem cells. Int J Cancer (2009) 0.75
Corrigendum: Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nat Commun (2015) 0.75
One step generation of fully chimeric antibodies using Cgamma1- and Ckappa mutant mice. J Immunother (2007) 0.75
The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. Int J Cancer (2009) 0.75
Corrigendum: S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat Immunol (2017) 0.75