Published in BMC Dev Biol on September 15, 2010
Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes. Circ Res (2014) 2.34
Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia. EMBO Mol Med (2012) 1.93
In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells. Cell Physiol Biochem (2011) 1.43
Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells. Stem Cells (2013) 1.29
Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. Stem Cells (2013) 1.28
Induced pluripotent stem cells for post-myocardial infarction repair: remarkable opportunities and challenges. Circ Res (2014) 1.09
Ca2+ signaling in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CM) from normal and catecholaminergic polymorphic ventricular tachycardia (CPVT)-afflicted subjects. Cell Calcium (2013) 1.07
Pluripotent stem cell models of human heart disease. Cold Spring Harb Perspect Med (2013) 1.01
Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells. Prog Biophys Mol Biol (2012) 1.00
Dual color photoactivation localization microscopy of cardiomyopathy-associated desmin mutants. J Biol Chem (2012) 0.99
The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening. Br J Pharmacol (2013) 0.94
Gene expression signatures of extracellular matrix and growth factors during embryonic stem cell differentiation. PLoS One (2012) 0.92
Cardiomyocytes derived from human induced pluripotent stem cells as models for normal and diseased cardiac electrophysiology and contractility. Prog Biophys Mol Biol (2012) 0.89
Concise review: drug discovery in the age of the induced pluripotent stem cell. Stem Cells Transl Med (2014) 0.86
3D-culture system for heart regeneration and cardiac medicine. Biomed Res Int (2013) 0.84
Human pluripotent stem cell-derived cardiomyocytes: response to TTX and lidocain reveals strong cell to cell variability. PLoS One (2012) 0.83
Induced pluripotent stem cells in cardiovascular medicine. Stem Cells Int (2011) 0.83
Automated grouping of action potentials of human embryonic stem cell-derived cardiomyocytes. IEEE Trans Biomed Eng (2014) 0.83
Current status of induced pluripotent stem cells in cardiac tissue regeneration and engineering. Regen Med Res (2013) 0.82
Differentiation of Cardiomyocytes from Human Pluripotent Stem Cells Using Monolayer Culture. Biomark Insights (2015) 0.80
Regionally diverse mitochondrial calcium signaling regulates spontaneous pacing in developing cardiomyocytes. Cell Calcium (2015) 0.79
Prospective in vitro models of channelopathies and cardiomyopathies. Stem Cells Int (2012) 0.79
Endogenous cardiac stem cells for the treatment of heart failure. Stem Cells Cloning (2013) 0.78
Reprogramming resistant genes: in-depth comparison of gene expressions among iPS, ES, and somatic cells. Front Physiol (2013) 0.77
The L-type Ca2+ channels blocker nifedipine represses mesodermal fate determination in murine embryonic stem cells. PLoS One (2013) 0.77
Bioluminescent imaging of genetically selected induced pluripotent stem cell-derived cardiomyocytes after transplantation into infarcted heart of syngeneic recipients. PLoS One (2014) 0.77
Calcium signaling in human stem cell-derived cardiomyocytes: Evidence from normal subjects and CPVT afflicted patients. Cell Calcium (2015) 0.77
Stem cell therapy for cardiovascular disease: the demise of alchemy and rise of pharmacology. Br J Pharmacol (2013) 0.76
Hearty miR-363 controls HAND1 in cardiac cell specification. Stem Cell Res Ther (2014) 0.75
Genetic and Epigenetic Profiling Reveals EZH2-mediated Down Regulation of OCT-4 Involves NR2F2 during Cardiac Differentiation of Human Embryonic Stem Cells. Sci Rep (2017) 0.75
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res (2000) 117.00
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature (2007) 28.24
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell (2007) 21.58
Generation of mouse induced pluripotent stem cells without viral vectors. Science (2008) 15.25
Epigenetic memory in induced pluripotent stem cells. Nature (2010) 14.31
Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A (2008) 13.09
Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell (2009) 11.65
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet (2009) 10.54
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell (2009) 10.52
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell (2005) 9.84
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol (2010) 9.24
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol (2007) 9.04
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res (2009) 7.09
Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest (2001) 6.59
Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation (2003) 6.30
Marked differences in differentiation propensity among human embryonic stem cell lines. Nat Biotechnol (2008) 6.19
Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ Res (2003) 5.12
Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res (2009) 3.44
Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation (2008) 3.11
Generation of functional murine cardiac myocytes from induced pluripotent stem cells. Circulation (2008) 3.11
Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS One (2009) 3.07
Cardiomyocyte differentiation of human induced pluripotent stem cells. Circulation (2009) 2.86
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One (2008) 2.85
Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell (2009) 2.78
Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS One (2009) 2.62
Dissecting Oct3/4-regulated gene networks in embryonic stem cells by expression profiling. PLoS One (2006) 2.46
Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data. BMC Genomics (2008) 2.27
Generation of insulin-secreting islet-like clusters from human skin fibroblasts. J Biol Chem (2008) 2.04
Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages. Stem Cells (2008) 1.83
Functional characteristics of ES cell-derived cardiac precursor cells identified by tissue-specific expression of the green fluorescent protein. J Cell Biol (1998) 1.66
Mayday--a microarray data analysis workbench. Bioinformatics (2006) 1.61
Distinct cardiogenic preferences of two human embryonic stem cell (hESC) lines are imprinted in their proteomes in the pluripotent state. Biochem Biophys Res Commun (2008) 1.59
Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells. Differentiation (2008) 1.56
Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. FASEB J (2009) 1.52
Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes. Stem Cells (2006) 1.52
Oct4 targets regulatory nodes to modulate stem cell function. PLoS One (2007) 1.52
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochem Biophys Res Commun (2009) 1.45
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun (2009) 1.44
Molecular characterization and functional properties of cardiomyocytes derived from human inducible pluripotent stem cells. J Cell Mol Med (2011) 1.43
Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett (2009) 1.43
Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts. Cell Biol Int (2009) 1.39
MEA-Tools: an open source toolbox for the analysis of multi-electrode data with MATLAB. J Neurosci Methods (2002) 1.23
Molecular signature of cardiomyocyte clusters derived from human embryonic stem cells. Stem Cells (2008) 1.16
Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells. Stem Cells (2009) 1.09
A comparison of murine smooth muscle cells generated from embryonic versus induced pluripotent stem cells. Stem Cells Dev (2009) 1.09
A transcriptional roadmap to the induction of pluripotency in somatic cells. Stem Cell Rev (2010) 1.09
Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance. Circ Res (2010) 1.04
Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells. Stem Cells (2009) 1.04
Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cell Physiol Biochem (2009) 1.02
Beta-adrenergic and muscarinic modulation of human embryonic stem cell-derived cardiomyocytes. Cell Physiol Biochem (2004) 0.97
Force measurements of human embryonic stem cell-derived cardiomyocytes in an in vitro transplantation model. Stem Cells (2006) 0.97
Retracted Generation of pluripotent stem cells from adult human testis. Nature (2008) 5.49
Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med (2004) 4.59
Regulatory T cells in cancer. Blood (2006) 3.56
Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci U S A (2002) 3.27
Generation of functional murine cardiac myocytes from induced pluripotent stem cells. Circulation (2008) 3.11
Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc Natl Acad Sci U S A (2002) 3.01
Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell (2006) 2.87
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood (2005) 2.81
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach. Arch Toxicol (2012) 2.17
Retracted Cav 2.3 (R-type) calcium channels are critical for mediating anticonvulsive and neuroprotective properties of lamotrigine in vivo. Epilepsia (2013) 2.05
Intrahepatic IL-8 producing Foxp3⁺CD4⁺ regulatory T cells and fibrogenesis in chronic hepatitis C. J Hepatol (2013) 2.03
Host-dependent tumorigenesis of embryonic stem cell transplantation in experimental stroke. J Cereb Blood Flow Metab (2003) 2.01
In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma. Blood (2006) 1.92
FOXO-dependent regulation of innate immune homeostasis. Nature (2010) 1.89
Organotypic slice culture from human adult ventricular myocardium. Cardiovasc Res (2011) 1.78
IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Ig alpha/beta. J Exp Med (2007) 1.75
Electrophysiological maturation and integration of murine fetal cardiomyocytes after transplantation. Circ Res (2007) 1.73
Effective engraftment but poor mid-term persistence of mononuclear and mesenchymal bone marrow cells in acute and chronic rat myocardial infarction. J Mol Cell Cardiol (2006) 1.72
IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res (2011) 1.59
Modulation of ventricular repolarization in patients with transient left ventricular apical ballooning: a case control study. J Cardiovasc Electrophysiol (2006) 1.59
Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. J Clin Invest (2006) 1.58
Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro. FASEB J (2009) 1.52
A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials. Genomics (2006) 1.51
Estimation of action potential changes from field potential recordings in multicellular mouse cardiac myocyte cultures. Cell Physiol Biochem (2003) 1.50
Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol (2011) 1.49
Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells. FASEB J (2010) 1.45
Cardiac specific differentiation of mouse embryonic stem cells. Cardiovasc Res (2003) 1.44
In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells. Cell Physiol Biochem (2011) 1.43
Toxicogenomics directory of chemically exposed human hepatocytes. Arch Toxicol (2014) 1.43
High-resolution transcriptome of human macrophages. PLoS One (2012) 1.42
Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin Cancer Res (2004) 1.42
Dendritic cells are significantly reduced in non-Hodgkin's lymphoma and express less CCR7 and CD62L. Leuk Lymphoma (2006) 1.39
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. FASEB J (2003) 1.36
Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines. J Neurosci (2009) 1.36
Elevated serum levels of CC thymus and activation-related chemokine (TARC) in primary Hodgkin's disease: potential for a prognostic factor. Cancer Res (2005) 1.32
miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood (2009) 1.25
Regulatory dendritic cells: there is more than just immune activation. Front Immunol (2012) 1.25
CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. Cancer Res (2013) 1.22
Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin. Immunity (2007) 1.21
Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species. J Biol Chem (2007) 1.19
Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18. J Cell Sci (2012) 1.18
The high mobility group protein HMGA2: a co-regulator of chromatin structure and pluripotency in stem cells? Stem Cell Rev (2009) 1.18
IDO-expressing regulatory dendritic cells in cancer and chronic infection. J Mol Med (Berl) (2007) 1.18
CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. Blood (2005) 1.17
Conventional light chains inhibit the autonomous signaling capacity of the B cell receptor. Immunity (2007) 1.17
Disturbances in glucose-tolerance, insulin-release, and stress-induced hyperglycemia upon disruption of the Ca(v)2.3 (alpha 1E) subunit of voltage-gated Ca(2+) channels. Mol Endocrinol (2002) 1.17
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. Cancer Res (2012) 1.16
Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma. Cancer Res (2006) 1.15
The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation. PLoS One (2009) 1.15
Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes. Genome Biol (2007) 1.15
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. Proc Natl Acad Sci U S A (2003) 1.14
Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases. Curr Med Chem (2009) 1.14
RNA fingerprints provide direct evidence for the inhibitory role of TGFbeta and PD-1 on CD4+ T cells in Hodgkin lymphoma. Blood (2007) 1.13
O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells. Eur J Immunol (2003) 1.12
The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells. Biol Chem (2008) 1.12
Activity of complex III of the mitochondrial electron transport chain is essential for early heart muscle cell differentiation. FASEB J (2004) 1.11
Blood-based gene expression signatures in non-small cell lung cancer. Clin Cancer Res (2011) 1.09
Retracted Silencing of B cell receptor signals in human naive B cells. J Exp Med (2002) 1.09
Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels. J Biol Chem (2002) 1.07
Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition. Proc Natl Acad Sci U S A (2009) 1.07
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome. Hum Mol Genet (2012) 1.07
Serpin-6 expression protects embryonic stem cells from lysis by antigen-specific CTL. J Immunol (2007) 1.07
Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles. Mol Ther (2012) 1.07
Involvement of reactive oxygen species in cardiotrophin-1-induced proliferation of cardiomyocytes differentiated from murine embryonic stem cells. Exp Cell Res (2004) 1.07
Concise review: role and function of the ubiquitin-proteasome system in mammalian stem and progenitor cells. Stem Cells (2007) 1.07
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. ALTEX (2010) 1.06
HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy. J Immunol (2002) 1.06
The isolated perfused bovine retina--a sensitive tool for pharmacological research on retinal function. Brain Res Brain Res Protoc (2005) 1.05
Establishment and characterization of a mouse embryonic heart slice preparation. Cell Physiol Biochem (2005) 1.05
Autoantibodies frequently detected in patients with aplastic anemia. Blood (2003) 1.05
Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells. PLoS One (2012) 1.05
Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells. Chem Res Toxicol (2014) 1.03
Electrocorticographic and deep intracerebral EEG recording in mice using a telemetry system. Brain Res Brain Res Protoc (2005) 1.03
Regulatory T cells: major players in the tumor microenvironment. Curr Pharm Des (2009) 1.02
Effects of gender and aging on differential autonomic responses to orthostatic maneuvers. J Cardiovasc Electrophysiol (2008) 1.02
Embryonic stem cell transplantation after experimental traumatic brain injury dramatically improves neurological outcome, but may cause tumors. J Neurotrauma (2007) 1.02
Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cell Physiol Biochem (2009) 1.02