Published in Ann Neurol on November 01, 2007
Immune activation in brain aging and neurodegeneration: too much or too little? Neuron (2009) 3.76
C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proc Natl Acad Sci U S A (2012) 1.73
Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation. Exp Neurol (2008) 1.44
Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation. Brain (2008) 1.38
Integrating pathways of Parkinson's disease in a molecular interaction map. Mol Neurobiol (2013) 1.34
Microglia and ischemic stroke: a double-edged sword. Int J Physiol Pathophysiol Pharmacol (2013) 1.33
Microglia activation and anti-inflammatory regulation in Alzheimer's disease. Mol Neurobiol (2010) 1.22
Dysregulated neuronal-microglial cross-talk during aging, stress and inflammation. Exp Neurol (2010) 1.12
The brain's best friend: microglial neurotoxicity revisited. Front Cell Neurosci (2013) 1.09
Myelin activates FAK/Akt/NF-kappaB pathways and provokes CR3-dependent inflammatory response in murine system. PLoS One (2010) 1.09
Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2013) 1.09
The emerging role of microRNAs in multiple sclerosis. Nat Rev Neurol (2010) 1.08
Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. J Exp Med (2012) 1.04
CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease. J Neuroinflammation (2011) 1.03
Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis. Neurol Res Int (2011) 1.00
The regulation of the CNS innate immune response is vital for the restoration of tissue homeostasis (repair) after acute brain injury: a brief review. Int J Inflam (2010) 0.99
MicroRNAs and Multiple Sclerosis. Autoimmune Dis (2010) 0.94
CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis. J Neurosci (2010) 0.92
Neuron-Microglia Dialogue and Hippocampal Neurogenesis in the Aged Brain. Aging Dis (2010) 0.92
The impact of neuroimmune changes on development of amyloid pathology; relevance to Alzheimer's disease. Immunology (2014) 0.91
The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target. Clin Dev Immunol (2012) 0.89
MicroRNAs as novel regulators of neuroinflammation. Mediators Inflamm (2013) 0.88
Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-κB pathway in microglia cells. PLoS One (2012) 0.86
Understanding the neurobiology of CD200 and the CD200 receptor: a therapeutic target for controlling inflammation in human brains? Future Neurol (2013) 0.85
Cleavage of osteopontin by matrix metalloproteinase-12 modulates experimental autoimmune encephalomyelitis disease in C57BL/6 mice. Am J Pathol (2010) 0.84
The rhesus rhadinovirus CD200 homologue affects immune responses and viral loads during in vivo infection. J Virol (2014) 0.84
Distribution and expression of CD200 in the rat respiratory system under normal and endotoxin-induced pathological conditions. J Anat (2010) 0.84
Neuronal influence behind the central nervous system regulation of the immune cells. Front Integr Neurosci (2013) 0.83
Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase. Rejuvenation Res (2008) 0.83
Immunoenrichment microwave and magnetic proteomics for quantifying CD47 in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Electrophoresis (2012) 0.83
Inhibition of CD200R1 expression by C/EBP β in reactive microglial cells. J Neuroinflammation (2012) 0.82
Genomic characterization of Japanese macaque rhadinovirus, a novel herpesvirus isolated from a nonhuman primate with a spontaneous inflammatory demyelinating disease. J Virol (2012) 0.81
Inhibition of 26S protease regulatory subunit 7 (MSS1) suppresses neuroinflammation. PLoS One (2012) 0.80
Regenerative Capacity of Macrophages for Remyelination. Front Cell Dev Biol (2016) 0.80
Attenuation of inflammatory-mediated neurotoxicity by Saururus chinensis extract in LPS-induced BV-2 microglia cells via regulation of NF-κB signaling and anti-oxidant properties. BMC Complement Altern Med (2014) 0.79
CD200R1 agonist attenuates glial activation, inflammatory reactions, and hypersensitivity immediately after its intrathecal application in a rat neuropathic pain model. J Neuroinflammation (2016) 0.78
Neuroinflammation and neuroimmune dysregulation after acute hypoxic-ischemic injury of developing brain. Front Pediatr (2015) 0.77
Agonistic CD200R1 DNA Aptamers Are Potent Immunosuppressants That Prolong Allogeneic Skin Graft Survival. Mol Ther Nucleic Acids (2014) 0.77
Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages. Front Cell Neurosci (2017) 0.75
Contributions of nonhematopoietic cells and mediators to immune responses: implications for immunotoxicology. Toxicol Sci (2015) 0.75
Epoch Analysis of On-Treatment Disability Progression Events over Time in the Tysabri Observational Program (TOP). PLoS One (2016) 0.75
Exploring potential mechanisms of action of natalizumab in secondary progressive multiple sclerosis. Ther Adv Neurol Disord (2016) 0.75
Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex. J Neuroinflammation (2016) 0.75
The potential neuroprotective role of a histone deacetylase inhibitor, sodium butyrate, after neonatal hypoxia-ischemia. J Neuroinflammation (2017) 0.75
Brain innate immunity in the regulation of neuroinflammation: therapeutic strategies by modulating CD200-CD200R interaction involve the cannabinoid system. Curr Pharm Des (2014) 0.75
Homogeneity of active demyelinating lesions in established multiple sclerosis. Ann Neurol (2008) 2.29
Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology. AJNR Am J Neuroradiol (2005) 2.07
The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions. J Neuropathol Exp Neurol (2005) 1.76
C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proc Natl Acad Sci U S A (2012) 1.73
Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium. Acta Neuropathol (2008) 1.51
Interactions between hemopoietically derived TNF and central nervous system-resident glial chemokines underlie initiation of autoimmune inflammation in the brain. J Immunol (2002) 1.42
Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis. Am J Pathol (2002) 1.42
Extensive hippocampal demyelination in multiple sclerosis. J Neuropathol Exp Neurol (2007) 1.40
Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study. J Neuropathol Exp Neurol (2010) 1.36
Longterm quiescent cells in the aged human subventricular neurogenic system specifically express GFAP-delta. Aging Cell (2010) 1.22
Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis. J Biol Chem (2010) 1.22
Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions. J Neuropathol Exp Neurol (2009) 1.16
GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo. J Immunol (2009) 1.15
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis. Neurobiol Dis (2005) 1.14
Spinal cord gray matter demyelination in multiple sclerosis-a novel pattern of residual plaque morphology. Brain Pathol (2006) 1.13
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice. Neurobiol Aging (2013) 1.12
The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes. Mol Immunol (2007) 1.12
Lack of CD200 enhances pathological T cell responses during influenza infection. J Immunol (2009) 1.11
Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis. Brain (2009) 1.09
Phenotyping primary human microglia: tight regulation of LPS responsiveness. Glia (2012) 1.06
The role of stress-response systems for the pathogenesis and progression of MS. Trends Immunol (2005) 1.05
Does high-field MR imaging improve cortical lesion detection in multiple sclerosis? J Neurol (2008) 1.05
Expression of the inhibitory CD200 receptor is associated with alternative macrophage activation. J Innate Immun (2009) 1.03
Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes. J Neuropathol Exp Neurol (2005) 1.03
Diminished aromatase immunoreactivity in the hypothalamus, but not in the basal forebrain nuclei in Alzheimer's disease. Neurobiol Aging (2005) 1.02
Extensive extracellular matrix depositions in active multiple sclerosis lesions. Neurobiol Dis (2006) 1.02
Spinal cord neuronal pathology in multiple sclerosis. Brain Pathol (2008) 1.01
An unusual mode of concerted evolution of the EGF-TM7 receptor chimera EMR2. FASEB J (2006) 1.01
Decreased expression of mineralocorticoid receptor mRNA and its splice variants in postmortem brain regions of patients with major depressive disorder. J Psychiatr Res (2010) 0.99
Spinal cord atrophy in multiple sclerosis caused by white matter volume loss. Arch Neurol (2005) 0.98
Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue. J Neuropathol Exp Neurol (2013) 0.97
Brain banking for neurological disorders. Lancet Neurol (2013) 0.97
The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes. J Leukoc Biol (2006) 0.97
The microtubule regulator stathmin is an endogenous protein agonist for TLR3. J Immunol (2010) 0.97
Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55. J Immunol (2013) 0.97
VCAM-1-positive microglia target oligodendrocytes at the border of multiple sclerosis lesions. J Neuropathol Exp Neurol (2002) 0.96
Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration. J Immunol (2008) 0.96
Spleen vagal denervation inhibits the production of antibodies to circulating antigens. PLoS One (2008) 0.94
Selective upregulation of scavenger receptors in and around demyelinating areas in multiple sclerosis. J Neuropathol Exp Neurol (2013) 0.90
NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions. Free Radic Biol Med (2006) 0.90
Vitamin D in the healthy and inflamed central nervous system: access and function. J Neurol Sci (2011) 0.88
GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors. PLoS One (2010) 0.88
Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain. Acta Neuropathol (2013) 0.87
Restoring immune suppression in the multiple sclerosis brain. Prog Neurobiol (2009) 0.87
HPA axis activity in multiple sclerosis correlates with disease severity, lesion type and gene expression in normal-appearing white matter. Acta Neuropathol (2013) 0.83
Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed. Glia (2013) 0.83
CCL5 and CCR5 genotypes modify clinical, radiological and pathological features of multiple sclerosis. J Neuroimmunol (2007) 0.81
Hypothalamo-pituitary-adrenal axis activity predicts disease progression in multiple sclerosis. J Neuroimmunol (2005) 0.80
Mast cell transcripts are increased within and outside multiple sclerosis lesions. J Neuroimmunol (2008) 0.80
A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense. PLoS One (2011) 0.80
BrainNet Europe's Code of Conduct for brain banking. J Neural Transm (Vienna) (2015) 0.79
Gender differences in multiple sclerosis: induction of estrogen signaling in male and progesterone signaling in female lesions. J Neuropathol Exp Neurol (2014) 0.79
Ligation of CD200R by CD200 is not required for normal murine myelopoiesis. Eur J Haematol (2007) 0.77
Stress of dying is not suppressed by high-dose morphine or by dementia. Neuropsychopharmacology (2004) 0.76
Co-expression of tyrosine hydroxylase and GTP cyclohydrolase I in arginine vasopressin-synthesizing neurons of the human supraoptic nucleus demonstrated by laser microdissection and real-time PCR. Neuroendocrinology (2006) 0.75