Published in Org Lett on September 19, 2007
Aerobic copper-catalyzed organic reactions. Chem Rev (2013) 1.54
Intracellular inducible alkylation system that exhibits antisense effects with greater potency and selectivity than the natural oligonucleotide. Angew Chem Int Ed Engl (2006) 0.93
Extensive sugar modification improves triple helix forming oligonucleotide activity in vitro but reduces activity in vivo. Biochemistry (2007) 0.92
Hybridization-promoted and cytidine-selective activation for cross-linking with the use of 2-amino-6-vinylpurine derivatives. J Org Chem (2005) 0.89
pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation. Biomacromolecules (2003) 0.89
Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors. Bioorg Med Chem Lett (2013) 0.87
Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate. Biomacromolecules (2005) 0.87
Site-specific covalent modification of RNA guided by functionality-transfer oligodeoxynucleotides. Bioconjug Chem (2009) 0.86
Site-specific mutagenesis by triple helix-forming oligonucleotides containing a reactive nucleoside analog. Nucleic Acids Res (2003) 0.85
Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages. Chembiochem (2005) 0.84
Development of efficient packaging method of oligodeoxynucleotides by a condensed nano particle in lipid envelope structure. Biol Pharm Bull (2005) 0.83
4-vinyl-substituted pyrimidine nucleosides exhibit the efficient and selective formation of interstrand cross-links with RNA and duplex DNA. Nucleic Acids Res (2013) 0.83
The alkyl-connected 2-amino-6-vinylpurine (AVP) crosslinking agent for improved selectivity to the cytosine base in RNA. Bioorg Med Chem (2010) 0.83
Adenosine-1,3-diazaphenoxazine derivative for selective base pair formation with 8-oxo-2'-deoxyguanosine in DNA. J Am Chem Soc (2011) 0.82
Pin-point chemical modification of RNA with diverse molecules through the functionality transfer reaction and the copper-catalyzed azide-alkyne cycloaddition reaction. Chem Commun (Camb) (2011) 0.82
Selective cross-linking to the adenine of the TA interrupting site within the triple helix. Bioorg Med Chem Lett (2002) 0.81
Alteration of cross-linking selectivity with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects. Bioorg Med Chem Lett (2010) 0.81
Specific fluorescent probe for 8-oxoguanosine. Angew Chem Int Ed Engl (2007) 0.81
Addition of a 2-month low-dose course of levofloxacin to long-term erythromycin therapy in sinobronchial syndrome. Respirology (2002) 0.80
Design of new bidentate ligands constructed of two Hoechst 33258 units for discrimination of the length of two A3T3 binding motifs. J Org Chem (2006) 0.80
Sequence- and base-specific delivery of nitric oxide to cytidine and 5-methylcytidine leading to efficient deamination. J Am Chem Soc (2004) 0.79
Activation and alteration of base selectivity by metal cations in the functionality-transfer reaction for RNA modification. Bioconjug Chem (2010) 0.79
A new odorless procedure for the synthesis of 2'-deoxy-6-thioguanosine and its incorporation into oligodeoxynucleotides. Nucleosides Nucleotides Nucleic Acids (2009) 0.79
An efficient and simple method for site-selective modification of O6-methyl-2'-deoxyguanosine in DNA. Chem Commun (Camb) (2012) 0.78
Recognition of CG interrupting site by W-shaped nucleoside analogs (WNA) having the pyrazole ring in an anti-parallel triplex DNA. Bioorg Med Chem (2009) 0.78
An efficient antigene activity and antiproliferative effect by targeting the Bcl-2 or survivin gene with triplex forming oligonucleotides containing a W-shaped nucleoside analogue (WNA-βT). Org Biomol Chem (2012) 0.78
Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN. Bioorg Med Chem Lett (2008) 0.78
Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes. J Org Chem (2006) 0.77
Expansion of triplex recognition codes by the use of novel bicyclic nucleoside derivatives (WNA). Nucleosides Nucleotides Nucleic Acids (2005) 0.77
Chemical tools for targeted mutagenesis of DNA based on triple helix formation. Biol Pharm Bull (2004) 0.77
A new usage of functionalized oligodeoxynucleotide probe for site-specific modification of a guanine base within RNA. Nucleic Acids Res (2010) 0.77
The ODN probes conjugating the Cu(II) complex enhance the luminol chemiluminescence by assembling on the DNA template. Bioorg Med Chem (2010) 0.77
Modification of the aromatic ring of the WNA analogues for expansion of the triplex recognition codes. Nucleic Acids Symp Ser (Oxf) (2005) 0.77
Development of a specific fluorescent probe for 8-oxoguanosine. Nucleic Acids Symp Ser (Oxf) (2007) 0.76
OFF-to-ON type fluorescent probe for the detection of 8-oxo-dG in DNA by the Adap-masked ODN probe. Bioorg Med Chem Lett (2011) 0.76
Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors. Bioorg Med Chem (2013) 0.76
Difference in brain distributions of carbon 11-labeled 4-hydroxy-2(1H)-quinolones as PET radioligands for the glycine-binding site of the NMDA ion channel. Nucl Med Biol (2008) 0.76
Incorporation of an inducible nucleotide analog into DNA by DNA polymerases. Bioorg Med Chem (2009) 0.76
Site-specific modification of RNA by functionality-transfer ODN probes. Nucleic Acids Symp Ser (Oxf) (2009) 0.76
Synthesis of the oligoribonucleotides incorporating 8-oxo-guanosine and evaluation of their base pairing properties. Nucleosides Nucleotides Nucleic Acids (2013) 0.76
Discrimination between 8-oxo-2'-deoxyguanosine and 2'-deoxyguanosine in DNA by the single nucleotide primer extension reaction with adap triphosphate. Angew Chem Int Ed Engl (2015) 0.76
The spermine-bisaryl conjugate as a potent inducer of B- to Z-DNA transition. Chemistry (2010) 0.76
Selective fluorescence detection of 8-oxoguanosine with 8-oxoG-clamp. Nucleosides Nucleotides Nucleic Acids (2007) 0.75
Synthesis of 8-oxoguanosine phosphoramidite and its incorporation. Curr Protoc Nucleic Acid Chem (2014) 0.75
Enhancement of TFO Triplex Formation by Conjugation with Pyrene via Click Chemistry. Chem Pharm Bull (Tokyo) (2015) 0.75
Efficient DNA strand displacement by a W-shaped nucleoside analogue (WNA-βT) containing an ortho-methyl-substituted phenyl ring. Chembiochem (2012) 0.75
Design of highly efficient and selective transfer reaction of nitrosyl group to dc and d(M)C resulting in specific deamination. Nucleosides Nucleotides Nucleic Acids (2005) 0.75
Cu2+ -mediated assembly of the minor groove binders on the DNA template with sequence selectivity. Org Lett (2006) 0.75
2-Amino-6-vinyl purine as a tool for post synthetic conjugation of DNA with radio-, spin-, fluorescence labels and peptides. Nucleic Acids Res Suppl (2002) 0.75
Discrimination of the length of two remote binding sites by the spacer-linked DNA minor groove binders. Nucleic Acids Symp Ser (Oxf) (2005) 0.75
Selective formation of non-natural type triplexes containing TA interrupting sites with the TFO incorporating W-shape nucleic acid (WNA) analogs. Nucleic Acids Res Suppl (2002) 0.75
Enhancements in the utilization of antigene oligonucleotides in the nucleus by booster oligonucleotides. Chem Commun (Camb) (2020) 0.75
Selective nitrosyl group transfer reaction to cytidine using oligonucleotides bearing S-nitrosothioguanosine. Nucleic Acids Symp Ser (Oxf) (2004) 0.75
Enzymatic incorporation of 2-amino-6-vinylpurine derivative. Nucleic Acids Symp Ser (Oxf) (2007) 0.75
Site-specific modification by functionality-transfer oligonucleotide with the photo-inducible reactivity. Nucleic Acids Symp Ser (Oxf) (2008) 0.75
Synthesis and evaluation of 4-bromo-1-(3-[18F]fluoropropyl)-2-nitroimidazole with a low energy LUMO orbital designed as brain hypoxia-targeting imaging agent. Biol Pharm Bull (2002) 0.75
New NitroG-Grasp Molecules with Enhanced Capture Reactivity for 8-Nitroguanosine in the Aqueous Media. Chem Pharm Bull (Tokyo) (2015) 0.75
Development of the novel drug releasing system triggered by hybridization with target sequence. Nucleosides Nucleotides Nucleic Acids (2007) 0.75
Efficient covalent capture of 8-nitroguanosine via a multiple hydrogen-bonded complex. Org Lett (2014) 0.75
Synthesis and brain regional distribution of [11C]NPS 1506 in mice and rat: an N-methyl-D-aspartate (NMDA) receptor antagonist. Biol Pharm Bull (2003) 0.75
An isocytidine derivative with a 2-amino-6-methylpyridine unit for selective recognition of the CG interrupting site in an antiparallel triplex DNA. Chembiochem (2014) 0.75
Enantioselective binding of chiral 1,14-dimethyl[5]helicene-spermine ligands with B- and Z-DNA. Bioorg Med Chem (2013) 0.75
Application of 2-amino-6-vinylpurine as an efficient agent for conjugation of oligonucleotides. Nucleosides Nucleotides Nucleic Acids (2006) 0.75
N-(guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site for the formation of anti-parallel triplexes. Org Biomol Chem (2013) 0.75
New DNA binding ligands as a model of chromomycin A3. Bioorg Med Chem Lett (2004) 0.75
Synthesis of the new nucleoside analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker. Nucleic Acids Symp Ser (Oxf) (2008) 0.75
Mutagenesis targeted by triple-helix forming oligonucleotides containing a reactive nucleoside analogue. Nucleic Acids Res Suppl (2002) 0.75
Synthesis and binding properties of new selective ligands for the nucleobase opposite the AP site. Bioorg Med Chem (2012) 0.75
Recognition of DNA with assembly of minor groove binders mediated by metal complexation. Nucleic Acids Symp Ser (Oxf) (2006) 0.75
Efficient cross-linking reactions by functional nucleobases capable of in situ activation under neutral conditions. Nucleic Acids Res Suppl (2003) 0.75
Structural activity relationship between Salmonella-mutagenicity and nitro-orientation of nitroazaphenanthrenes. Chem Biol Interact (2003) 0.75
Fluorescence detection of 8-oxoguanosine by G-clamp derivatives. Nucleic Acids Symp Ser (Oxf) (2006) 0.75
Efficient Thymidine-Selective DNA Interstrand Photo-activated Crosslinking by the 6-Thioguanine Connected via an Ethylene-Linker to the 2'-Deoxyribose Unit. Chem Pharm Bull (Tokyo) (2016) 0.75
Fluorescence and chemiluminescence properties of indolylmaleimides: experimental and theoretical studies. Phys Chem Chem Phys (2010) 0.75
Synthesis of new derivatives of 8-oxoG-clamp for better understanding the recognition mode and improvement of selective affinity. Bioorg Med Chem (2010) 0.75
Effective strand invasion ODN incorporating a new bicyclic nucleoside analogue (WNA). Nucleic Acids Symp Ser (Oxf) (2007) 0.75
Equilibrium shift by target DNA substrates for determination of DNA binding ligands. Bioorg Med Chem Lett (2006) 0.75
B-Z transition of (dA-T)(n) duplexes induced by a spermine porphyrin-conjugate via an intermediate DNA conformation. Chem Commun (Camb) (2013) 0.75
Properties of oligonucleotide with phenyl-substituted carbocyclic nucleoside analogs for the formation of duplex and triplex DNA. Nucleosides Nucleotides Nucleic Acids (2012) 0.75
Design and evaluation of novel nucleoside analogs (WNA) for specific formation of non-natural type triplexes containing a TA or CG interrupting site. Nucleic Acids Res Suppl (2003) 0.75
Effects of 5-substituted pyrimidine nucleoside bases of WNA on stability of triplex DNA. Nucleic Acids Symp Ser (Oxf) (2004) 0.75
Substituent effects on the in situ activation of the double activated cross-linking reaction. Nucleic Acids Symp Ser (Oxf) (2005) 0.75
Novel drug releasing system triggered by hybridization with target sequence. Nucleic Acids Symp Ser (Oxf) (2006) 0.75
Binding of two bis-bipyridine minor groove binders to a DNA template in the presence of Cu2+ ions. Nucleic Acids Symp Ser (Oxf) (2008) 0.75
Synthesis and evaluation of the functional oligonucleotides-PEG conjugates. Nucleic Acids Symp Ser (Oxf) (2004) 0.75
Synthesis and evaluation of the luciferase-oligodeoxynucleotide for the sequence-selective detection of nucleic acids. Arch Pharm (Weinheim) (2008) 0.75
Evaluation of the antisense effect of PEGylated oligodeoxynucleotides containing intelligent nucleoside analogues. Nucleic Acids Symp Ser (Oxf) (2009) 0.75
Formation of a stable triplex incorporating a CG interrupting site by a new WNA derivative containing 3-aminopyrazole as a nucleobase. Nucleic Acids Symp Ser (Oxf) (2008) 0.75
Development of novel thioguanosine analogs with the ability to specifically modify cytidine. Nucleic Acids Symp Ser (Oxf) (2007) 0.75
Effects of the modified aromatic ring of WNA on stability of triplex DNA. Nucleic Acids Symp Ser (Oxf) (2006) 0.75