Published in Biochemistry on August 11, 2007
The triple helix: 50 years later, the outcome. Nucleic Acids Res (2008) 1.73
Triplex technology in studies of DNA damage, DNA repair, and mutagenesis. Biochimie (2011) 1.67
Repair of DNA lesions associated with triplex-forming oligonucleotides. Mol Carcinog (2009) 1.36
DNA triple helices: biological consequences and therapeutic potential. Biochimie (2008) 1.24
Triplexator: detecting nucleic acid triple helices in genomic and transcriptomic data. Genome Res (2012) 1.12
Targeting of an interrupted polypurine:polypyrimidine sequence in mammalian cells by a triplex-forming oligonucleotide containing a novel base analogue. Biochemistry (2010) 0.92
Oligo/polynucleotide-based gene modification: strategies and therapeutic potential. Oligonucleotides (2011) 0.87
An update on targeted gene repair in mammalian cells: methods and mechanisms. J Biomed Sci (2011) 0.84
DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine. Nucleic Acids Res (2009) 0.82
Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA. Chem Commun (Camb) (2009) 0.79
Structural determinants of photoreactivity of triplex forming oligonucleotides conjugated to psoralens. J Nucleic Acids (2010) 0.75
Formation and repair of interstrand cross-links in DNA. Chem Rev (2006) 2.91
The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2. Mol Cell (2004) 2.60
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell (2010) 2.36
Polymer-based siRNA delivery: perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery. J Control Release (2007) 2.22
XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nat Chem Biol (2011) 1.89
DNA interstrand crosslink repair in mammalian cells: step by step. Crit Rev Biochem Mol Biol (2010) 1.82
Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nat Biotechnol (2009) 1.59
Critical Care Delivery: The Importance of Process of Care and ICU Structure to Improved Outcomes: An Update From the American College of Critical Care Medicine Task Force on Models of Critical Care. Crit Care Med (2015) 1.49
The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice. J Lipid Res (2009) 1.48
Zn2+ ions: modulators of excitatory and inhibitory synaptic activity. Neuroscientist (2004) 1.46
Endothelial progenitor cell function inversely correlates with long-term glucose control in diabetic patients: association with the attenuation of the heme oxygenase-adiponectin axis. Can J Cardiol (2012) 1.46
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage. Stem Cells (2008) 1.43
Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther (2008) 1.42
In vitro and in vivo pharmacological characterization of 5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-one (indacaterol), a novel inhaled beta(2) adrenoceptor agonist with a 24-h duration of action. J Pharmacol Exp Ther (2006) 1.42
Linkage between Werner syndrome protein and the Mre11 complex via Nbs1. J Biol Chem (2004) 1.36
The DNA translocase FANCM/MHF promotes replication traverse of DNA interstrand crosslinks. Mol Cell (2013) 1.32
Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acids. Proc Natl Acad Sci U S A (2008) 1.25
Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cells. J Biol Chem (2009) 1.22
Cell cycle modulation of gene targeting by a triple helix-forming oligonucleotide. J Biol Chem (2003) 1.21
A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network. Mol Cell (2012) 1.19
Mispair-aligned N3T-alkyl-N3T interstrand cross-linked DNA: synthesis and characterization of duplexes with interstrand cross-links of variable lengths. J Am Chem Soc (2004) 1.18
Psoralen conjugates for visualization of genomic interstrand cross-links localized by laser photoactivation. Bioconjug Chem (2007) 1.15
Distortion-dependent unhooking of interstrand cross-links in mammalian cell extracts. Biochemistry (2008) 1.13
Importance of clustered 2'-O-(2-aminoethyl) residues for the gene targeting activity of triple helix-forming oligonucleotides. Biochemistry (2004) 1.10
Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidines. J Am Chem Soc (2008) 1.10
Preparation of interstrand cross-linked DNA oligonucleotide duplexes. Front Biosci (2004) 1.09
Initiation of DNA interstrand cross-link repair in mammalian cells. Environ Mol Mutagen (2010) 1.09
Endothelial-specific CYP4A2 overexpression leads to renal injury and hypertension via increased production of 20-HETE. Am J Physiol Renal Physiol (2009) 1.09
Small-scale extracts for the study of nucleotide excision repair and non-homologous end joining. Nucleic Acids Res (2007) 1.08
N(4)C-ethyl-N(4)C cross-linked DNA: synthesis and characterization of duplexes with interstrand cross-links of different orientations. Biochemistry (2002) 1.07
Triplex targeted genomic crosslinks enter separable deletion and base substitution pathways. Nucleic Acids Res (2005) 1.07
Excessive dynamic airway collapse for the internist: new nomenclature or different entity? Postgrad Med J (2011) 1.05
Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade. Stem Cell Res Ther (2013) 1.04
Minimum number of 2'-O-(2-aminoethyl) residues required for gene knockout activity by triple helix forming oligonucleotides. Biochemistry (2002) 1.04
Dexmedetomidine infusion as adjunctive therapy to benzodiazepines for acute alcohol withdrawal. Ann Pharmacother (2008) 1.03
A human neuronal tissue culture model for Lesch-Nyhan disease. J Neurochem (2007) 1.01
Structure, flexibility, and repair of two different orientations of the same alkyl interstrand DNA cross-link. Biochemistry (2005) 1.01
Structure of a DNA repair substrate containing an alkyl interstrand cross-link at 1.65 A resolution. Biochemistry (2007) 1.00
EET agonist prevents adiposity and vascular dysfunction in rats fed a high fat diet via a decrease in Bach 1 and an increase in HO-1 levels. Prostaglandins Other Lipid Mediat (2011) 0.99
Heme oxygenase-2 deletion causes endothelial cell activation marked by oxidative stress, inflammation, and angiogenesis. J Pharmacol Exp Ther (2009) 0.98
Cross-link structure affects replication-independent DNA interstrand cross-link repair in mammalian cells. Biochemistry (2010) 0.95
Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U. Biochemistry (2002) 0.94
4-(2-aminooxyethoxy)-2-(ethylureido)quinoline-oligonucleotide conjugates: synthesis, binding interactions, and derivatization with peptides. Bioconjug Chem (2003) 0.93
Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response. Mol Cell Biol (2013) 0.93
Lipid membrane interactions of indacaterol and salmeterol: do they influence their pharmacological properties? Eur J Pharm Sci (2009) 0.93
Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21. Obesity (Silver Spring) (2013) 0.93
Intracellular inducible alkylation system that exhibits antisense effects with greater potency and selectivity than the natural oligonucleotide. Angew Chem Int Ed Engl (2006) 0.93
Targeted gene knock in and sequence modulation mediated by a psoralen-linked triplex-forming oligonucleotide. J Biol Chem (2008) 0.92
Effect of cross-link structure on DNA interstrand cross-link repair synthesis. Chem Res Toxicol (2009) 0.92
Werner syndrome protein 1367 variants and disposition towards coronary artery disease in Caucasian patients. Mech Ageing Dev (2004) 0.90
The development of bioactive triple helix-forming oligonucleotides. Ann N Y Acad Sci (2005) 0.90
Hybridization-promoted and cytidine-selective activation for cross-linking with the use of 2-amino-6-vinylpurine derivatives. J Org Chem (2005) 0.89
Human replication protein A melts a DNA triple helix structure in a potent and specific manner. Biochemistry (2008) 0.89
Triplex-induced recombination and repair in the pyrimidine motif. Nucleic Acids Res (2005) 0.89
pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation. Biomacromolecules (2003) 0.89
Peroxisome proliferator-activated receptor δ agonist, HPP593, prevents renal necrosis under chronic ischemia. PLoS One (2013) 0.89
ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions. Cancer Res (2013) 0.88
Dual pathways of carbon monoxide-mediated vasoregulation: modulation by redox mechanisms. Circ Res (2009) 0.88
Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors. Bioorg Med Chem Lett (2013) 0.87
Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate. Biomacromolecules (2005) 0.87
Alcohol withdrawal syndrome. Crit Care Clin (2012) 0.86
Site-specific covalent modification of RNA guided by functionality-transfer oligodeoxynucleotides. Bioconjug Chem (2009) 0.86
The RecQ helicase RECQL5 participates in psoralen-induced interstrand cross-link repair. Carcinogenesis (2013) 0.86
A novel link to base excision repair? Trends Biochem Sci (2010) 0.86
N(4)C-alkyl-N(4)C cross-linked DNA: bending deformations in duplexes that contain a -CNG- interstrand cross-link. Biochemistry (2002) 0.86
3'-methylphosphonate-modified oligo-2'-O-methylribonucleotides and their Tat peptide conjugates: uptake and stability in mouse fibroblasts in culture. Bioconjug Chem (2004) 0.86
Arsenite binds to the RING finger domains of RNF20-RNF40 histone E3 ubiquitin ligase and inhibits DNA double-strand break repair. J Am Chem Soc (2014) 0.85
Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes. Front Physiol (2012) 0.85
The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist. J Med Chem (2010) 0.85
Site-specific mutagenesis by triple helix-forming oligonucleotides containing a reactive nucleoside analog. Nucleic Acids Res (2003) 0.85
Age-related disease association of endogenous γ-H2AX foci in mononuclear cells derived from leukapheresis. PLoS One (2012) 0.84
Cyclooxygenase-2 dependent metabolism of 20-HETE increases adiposity and adipocyte enlargement in mesenchymal stem cell-derived adipocytes. J Lipid Res (2013) 0.84
Targeted cross-linking of the human beta-globin gene in living cells mediated by a triple helix forming oligonucleotide. Biochemistry (2006) 0.84
Inhibition of HIV tat-TAR interactions by an antisense oligo-2'-O-methylribonucleoside methylphosphonate. Bioorg Med Chem Lett (2003) 0.84