Published in Exp Eye Res on August 15, 2007
Homeostasis in the vertebrate lens: mechanisms of solute exchange. Philos Trans R Soc Lond B Biol Sci (2011) 0.93
Relocalization of a microtubule-anchoring protein, ninein, from the centrosome to dendrites during differentiation of mouse neurons. Histochem Cell Biol (2009) 0.87
Nedd1 expression as a marker of dynamic centrosomal localization during mouse embryonic development. Histochem Cell Biol (2008) 0.85
The molecular mechanisms underlying lens fiber elongation. Exp Eye Res (2016) 0.75
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO J (2003) 3.77
Enhanced dendritic cell antigen capture via toll-like receptor-induced actin remodeling. Science (2004) 3.08
Essential role of PDK1 in regulating cell size and development in mice. EMBO J (2002) 2.93
Molecular mechanisms of kinetochore capture by spindle microtubules. Nature (2005) 2.90
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. Biochem J (2010) 2.82
Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet (2003) 2.73
Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP. Curr Biol (2009) 2.48
Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization. Biochem J (2010) 2.43
The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation. EMBO J (2004) 2.11
Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1. Am J Physiol Endocrinol Metab (2005) 2.04
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion. EMBO J (2002) 1.83
Inhibition of autophagy in mitotic animal cells. Traffic (2002) 1.81
Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates. EMBO J (2004) 1.77
Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress. J Cell Biol (2006) 1.68
Analysis of the LKB1-STRAD-MO25 complex. J Cell Sci (2004) 1.65
Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein. Mol Biol Cell (2002) 1.64
Translocation of small heat shock proteins to the actin cytoskeleton upon proteasomal inhibition. J Mol Cell Cardiol (2002) 1.59
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways. J Cell Sci (2011) 1.55
TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages. J Cell Sci (2008) 1.52
Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Res (2004) 1.49
14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK. J Cell Sci (2005) 1.46
Proof that Burkholderia strains form effective symbioses with legumes: a study of novel Mimosa-nodulating strains from South America. Appl Environ Microbiol (2005) 1.44
BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm. Proc Natl Acad Sci U S A (2013) 1.44
Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo. J Cell Sci (2003) 1.44
New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion. Sci Signal (2010) 1.43
WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate. Biochem J (2004) 1.43
The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells. J Cell Biol (2002) 1.43
Altered aggregation properties of mutant gamma-crystallins cause inherited cataract. EMBO J (2002) 1.35
The C terminus of lens aquaporin 0 interacts with the cytoskeletal proteins filensin and CP49. Invest Ophthalmol Vis Sci (2006) 1.35
Nodulation of Mimosa spp. by the beta-proteobacterium Ralstonia taiwanensis. Mol Plant Microbe Interact (2003) 1.31
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. J Allergy Clin Immunol (2013) 1.30
The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number. J Biol Chem (2005) 1.30
Glucocorticoid-induced autophagy in osteocytes. J Bone Miner Res (2010) 1.29
A Gja8 (Cx50) point mutation causes an alteration of alpha 3 connexin (Cx46) in semi-dominant cataracts of Lop10 mice. Hum Mol Genet (2002) 1.28
The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation. Biochem J (2006) 1.27
Knockout of the intermediate filament protein CP49 destabilises the lens fibre cell cytoskeleton and decreases lens optical quality, but does not induce cataract. Exp Eye Res (2003) 1.26
Comparison of the small heat shock proteins alphaB-crystallin, MKBP, HSP25, HSP20, and cvHSP in heart and skeletal muscle. Histochem Cell Biol (2004) 1.26
Functions of the intermediate filament cytoskeleton in the eye lens. J Clin Invest (2009) 1.26
Trypanosoma brucei glycoproteins contain novel giant poly-N-acetyllactosamine carbohydrate chains. J Biol Chem (2004) 1.24
Desmin aggregate formation by R120G alphaB-crystallin is caused by altered filament interactions and is dependent upon network status in cells. Mol Biol Cell (2004) 1.23
ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa. Biochem J (2011) 1.17
Burkholderia phymatum is a highly effective nitrogen-fixing symbiont of Mimosa spp. and fixes nitrogen ex planta. New Phytol (2007) 1.17
Fin development in a cartilaginous fish and the origin of vertebrate limbs. Nature (2002) 1.16
Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex. J Cell Sci (2007) 1.16
The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27. Am J Hum Genet (2006) 1.13
Glial fibrillary acidic protein filaments can tolerate the incorporation of assembly-compromised GFAP-delta, but with consequences for filament organization and alphaB-crystallin association. Mol Biol Cell (2008) 1.12
Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells. Cell Motil Cytoskeleton (2009) 1.11
Bfsp2 mutation found in mouse 129 strains causes the loss of CP49' and induces vimentin-dependent changes in the lens fibre cell cytoskeleton. Exp Eye Res (2004) 1.11
Proximal effects of Toll-like receptor activation in dendritic cells. Curr Opin Immunol (2006) 1.11
Diverse gap junctions modulate distinct mechanisms for fiber cell formation during lens development and cataractogenesis. Development (2006) 1.10
p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase. J Biol Chem (2004) 1.07
FGF-2 release from the lens capsule by MMP-2 maintains lens epithelial cell viability. Mol Biol Cell (2007) 1.07
Lens major intrinsic protein (MIP)/aquaporin 0 expression in rat lens epithelia explants requires fibroblast growth factor-induced ERK and JNK signaling. J Biol Chem (2004) 1.06
Alexander-disease mutation of GFAP causes filament disorganization and decreased solubility of GFAP. J Cell Sci (2005) 1.06
Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation. J Cell Sci (2006) 1.05
R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable. FEBS J (2005) 1.04
Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells. J Biol Chem (2008) 1.04
The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation. J Biol Chem (2008) 1.02
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent. J Cell Biol (2008) 1.02
Association of clathrin, AP-2 adaptor and actin cytoskeleton with developing interlocking membrane domains of lens fibre cells. Exp Eye Res (2003) 1.01
Activated cAMP receptors switch encystation into sporulation. Proc Natl Acad Sci U S A (2009) 1.00
Knock-in of alpha3 connexin prevents severe cataracts caused by an alpha8 point mutation. J Cell Sci (2006) 0.99
Ninein is released from the centrosome and moves bi-directionally along microtubules. J Cell Sci (2007) 0.97
Cellular responses to the metal-binding properties of metformin. Diabetes (2012) 0.96
A spontaneous mutation affects programmed cell death during development of the rat eye. Exp Eye Res (2005) 0.95
Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1. Biochem J (2004) 0.95
Intermediate filament transcription in astrocytes is repressed by proteasome inhibition. FASEB J (2009) 0.95
A role for ARF6 in dendritic cell podosome formation and migration. Eur J Immunol (2008) 0.94
A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol (2009) 0.94
Homeostasis in the vertebrate lens: mechanisms of solute exchange. Philos Trans R Soc Lond B Biol Sci (2011) 0.93
Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. Int J Biochem Cell Biol (2008) 0.92
Multicellular rosette formation during cell ingression in the avian primitive streak. Dev Dyn (2008) 0.92
Insights into the beaded filament of the eye lens. Exp Cell Res (2007) 0.91
Observation of keratin particles showing fast bidirectional movement colocalized with microtubules. J Cell Sci (2003) 0.91
Nuclear speckle localisation of the small heat shock protein alpha B-crystallin and its inhibition by the R120G cardiomyopathy-linked mutation. Exp Cell Res (2003) 0.90
Gap junctions are selectively associated with interlocking ball-and-sockets but not protrusions in the lens. Mol Vis (2010) 0.90
Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1. Biochem J (2003) 0.89
Lenticular chaperones suppress the aggregation of the cataract-causing mutant T5P gamma C-crystallin. Exp Cell Res (2006) 0.89
Gap junction remodeling associated with cholesterol redistribution during fiber cell maturation in the adult chicken lens. Mol Vis (2009) 0.89
Foot-and-mouth disease virus 3C protease induces fragmentation of the Golgi compartment and blocks intra-Golgi transport. J Virol (2013) 0.88
Lens cells: more than meets the eye. Int J Biochem Cell Biol (2007) 0.88
Stochastically determined directed movement explains the dominant small-scale mitochondrial movements within non-neuronal tissue culture cells. FEBS Lett (2009) 0.87
Alexander disease causing mutations in the C-terminal domain of GFAP are deleterious both to assembly and network formation with the potential to both activate caspase 3 and decrease cell viability. Exp Cell Res (2011) 0.87
Sigma receptor antagonists inhibit human lens cell growth and induce pigmentation. Invest Ophthalmol Vis Sci (2005) 0.86
The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation. J Cell Sci (2013) 0.86
A developmental defect in astrocytes inhibits programmed regression of the hyaloid vasculature in the mammalian eye. Eur J Cell Biol (2011) 0.86
Association of the nuclear matrix component NuMA with the Cajal body and nuclear speckle compartments during transitions in transcriptional activity in lens cell differentiation. Eur J Cell Biol (2002) 0.85
Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6. Sci Rep (2013) 0.85
Multiple sites in αB-crystallin modulate its interactions with desmin filaments assembled in vitro. PLoS One (2011) 0.85