PubRank

Jules A Hoffmann

Author PubWeight™ 88.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Immunity-related genes and gene families in Anopheles gambiae. Science 2002 5.47
2 Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila. Nat Immunol 2006 4.69
3 The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila. Nat Immunol 2005 4.49
4 The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections. Nat Rev Immunol 2007 3.88
5 The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein. Nature 2002 3.63
6 Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila. Cell 2005 3.22
7 Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei. Immunity 2006 3.16
8 Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling. Nat Immunol 2003 2.99
9 Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening. EMBO J 2003 2.87
10 Dual detection of fungal infections in Drosophila via recognition of glucans and sensing of virulence factors. Cell 2006 2.66
11 Genetic analysis of resistance to viral infection. Nat Rev Immunol 2007 2.47
12 Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice. Nat Immunol 2007 2.36
13 Activation of Drosophila Toll during fungal infection by a blood serine protease. Science 2002 2.31
14 Two mosquito LRR proteins function as complement control factors in the TEP1-mediated killing of Plasmodium. Cell Host Microbe 2009 2.28
15 Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2. PLoS Pathog 2006 2.27
16 A serpin mutant links Toll activation to melanization in the host defence of Drosophila. EMBO J 2002 2.22
17 Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections. Nat Immunol 2001 2.18
18 The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila. Nat Immunol 2008 2.18
19 Dual activation of the Drosophila toll pathway by two pattern recognition receptors. Science 2003 2.11
20 A model of bacterial intestinal infections in Drosophila melanogaster. PLoS Pathog 2007 2.02
21 Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of Gram-positive bacteria. Nat Immunol 2004 1.93
22 The Drosophila immune defense against gram-negative infection requires the death protein dFADD. Immunity 2002 1.66
23 New insights into Drosophila larval haemocyte functions through genome-wide analysis. Cell Microbiol 2005 1.66
24 Sensing and signaling during infection in Drosophila. Curr Opin Immunol 2005 1.49
25 Prophenoloxidase activation is not required for survival to microbial infections in Drosophila. EMBO Rep 2006 1.49
26 NF-kappaB in the immune response of Drosophila. Cold Spring Harb Perspect Biol 2009 1.41
27 Broad RNA interference-mediated antiviral immunity and virus-specific inducible responses in Drosophila. J Immunol 2012 1.40
28 Pillars article: the dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell. 1996. 86: 973-983. J Immunol 2012 1.38
29 RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila. Proc Natl Acad Sci U S A 2010 1.34
30 Notch signaling controls lineage specification during Drosophila larval hematopoiesis. Curr Biol 2002 1.32
31 Fz2 and cdc42 mediate melanization and actin polymerization but are dispensable for Plasmodium killing in the mosquito midgut. PLoS Pathog 2006 1.21
32 Sensing infection in Drosophila: Toll and beyond. Semin Immunol 2004 1.20
33 Tissue and stage-specific expression of the Tolls in Drosophila embryos. Gene Expr Patterns 2002 1.18
34 PVF2, a PDGF/VEGF-like growth factor, induces hemocyte proliferation in Drosophila larvae. EMBO Rep 2002 1.17
35 Drosophila melanogaster antimicrobial defense. J Infect Dis 2003 1.07
36 The N-terminal domain of Drosophila Gram-negative binding protein 3 (GNBP3) defines a novel family of fungal pattern recognition receptors. J Biol Chem 2009 1.02
37 ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections. Proc Natl Acad Sci U S A 2011 1.01
38 Toll signaling: the TIReless quest for specificity. Nat Immunol 2003 1.00
39 big bang gene modulates gut immune tolerance in Drosophila. Proc Natl Acad Sci U S A 2013 0.95
40 Toll-dependent and Toll-independent immune responses in Drosophila. J Endotoxin Res 2004 0.92
41 Drosophila EYA regulates the immune response against DNA through an evolutionarily conserved threonine phosphatase motif. PLoS One 2012 0.88
42 Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge. Proc Natl Acad Sci U S A 2013 0.85
43 Peptidomic and proteomic analyses of the systemic immune response of Drosophila. Biochimie 2004 0.85
44 Spheniscins, avian beta-defensins in preserved stomach contents of the king penguin, Aptenodytes patagonicus. J Biol Chem 2003 0.83
45 The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response. J Biol Chem 2014 0.77