Published in Chembiochem on November 23, 2007
Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chem Biol (2015) 1.33
Design and Applications of Bifunctional Small Molecules: Why Two Heads Are Better Than One. ACS Chem Biol (2008) 1.25
Small-molecule control of intracellular protein levels through modulation of the ubiquitin proteasome system. Angew Chem Int Ed Engl (2014) 1.18
Chemical inducers of targeted protein degradation. J Biol Chem (2010) 1.07
Inhibitor mediated protein degradation. Chem Biol (2012) 1.02
HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol (2015) 0.99
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Two-headed PROTAC: an effective new tool for targeted protein degradation. Chembiochem (2010) 0.86
Impact of linker length on the activity of PROTACs. Mol Biosyst (2010) 0.83
Jostling for position: optimizing linker location in the design of estrogen receptor-targeting PROTACs. ChemMedChem (2010) 0.81
PROTAC-induced proteolytic targeting. Methods Mol Biol (2012) 0.75
Targeted Protein Degradation: from Chemical Biology to Drug Discovery. Cell Chem Biol (2017) 0.75
The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR. Genes Dev (2004) 8.42
The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome. Nat Biotechnol (2012) 2.14
Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis. Environ Health Perspect (2008) 1.86
Analysis of the Arabidopsis nuclear proteome and its response to cold stress. Plant J (2003) 1.50
LMP2-specific inhibitors: chemical genetic tools for proteasome biology. Chem Biol (2007) 1.35
Healthy Twin: a twin-family study of Korea--protocols and current status. Twin Res Hum Genet (2006) 1.27
Ionothermal syntheses of six three-dimensional zinc metal-organic frameworks with 1-alkyl-3-methylimidazolium bromide ionic liquids as solvents. Inorg Chem (2007) 1.17
Overexpression of SOD in retina: need for increase in H2O2-detoxifying enzyme in same cellular compartment. Free Radic Biol Med (2011) 1.14
Integrating human pluripotent stem cells into drug development. Cell Stem Cell (2013) 1.05
Identification of specific let-7 microRNA binding complexes in Caenorhabditis elegans. RNA (2008) 1.02
Peptide/graphene hybrid assembly into core/shell nanowires. Adv Mater (2010) 1.02
Do we need more twin studies? The Healthy Twin Study, Korea. Int J Epidemiol (2006) 1.00
Role of the xenobiotic receptor in inflammatory bowel disease. Inflamm Bowel Dis (2010) 1.00
Involvement of p38 MAP kinase during iron chelator-mediated apoptotic cell death. Cell Immunol (2002) 0.98
Simple method for quantitative analysis of N-linked glycoproteins in hepatocellular carcinoma specimens. J Proteome Res (2010) 0.96
Induction and localization of NOD2 protein in human endothelial cells. Cell Immunol (2005) 0.95
Molecular basis of the selectivity of the immunoproteasome catalytic subunit LMP2-specific inhibitor revealed by molecular modeling and dynamics simulations. J Phys Chem B (2010) 0.95
Catalposide, a compound isolated from catalpa ovata, attenuates induction of intestinal epithelial proinflammatory gene expression and reduces the severity of trinitrobenzene sulfonic Acid-induced colitis in mice. Inflamm Bowel Dis (2004) 0.95
Inflexinol inhibits colon cancer cell growth through inhibition of nuclear factor-kappaB activity via direct interaction with p50. Mol Cancer Ther (2009) 0.93
Prevalence of Helicobacter hepaticus, murine norovirus, and Pneumocystis carinii and eradication efficacy of cross-fostering in genetically engineered mice. Exp Anim (2009) 0.92
Product control by halide ions of ionic liquids in the ionothermal syntheses of Ni-(H)BTC metal-organic frameworks. Chem Commun (Camb) (2009) 0.91
Polyelectrolyte brush amplified electroactuation of microcantilevers. Nano Lett (2008) 0.89
Significant association between IL-17F promoter region polymorphism and susceptibility to asthma in a Korean population. Int Arch Allergy Immunol (2010) 0.89
Selection of an antiviral RNA aptamer against hemagglutinin of the subtype H5 avian influenza virus. Nucleic Acid Ther (2011) 0.89
8-hydroxydeoxyguanosine causes death of human leukemia cells deficient in 8-oxoguanine glycosylase 1 activity by inducing apoptosis. Mol Cancer Res (2003) 0.88
Retracted Diabetic HDL-associated myristic acid inhibits acetylcholine-induced nitric oxide generation by preventing the association of endothelial nitric oxide synthase with calmodulin. Am J Physiol Cell Physiol (2007) 0.87
Prevotella intermedia lipopolysaccharide stimulates release of nitric oxide by inducing expression of inducible nitric oxide synthase. J Periodontal Res (2004) 0.86
Surface-associated material from Porphyromonas gingivalis stimulates the release of nitric oxide by inducing expression of inducible nitric oxide synthase. Microbes Infect (2005) 0.85
Kaempferol inhibits P. intermedia lipopolysaccharide-induced production of nitric oxide through translational regulation in murine macrophages: critical role of heme oxygenase-1-mediated ROS reduction. J Periodontol (2012) 0.85
Prevotella intermedia lipopolysaccharide stimulates release of tumor necrosis factor-alpha through mitogen-activated protein kinase signaling pathways in monocyte-derived macrophages. FEMS Immunol Med Microbiol (2007) 0.85
Chemoproteomic analysis of intertissue and interspecies isoform diversity of AMP-activated protein kinase (AMPK). J Biol Chem (2013) 0.85
Resonance Raman studies of xanthine oxidase: The reduced enzyme-product complex with violapterin. J Phys Chem B (2005) 0.85
Activity-based near-infrared fluorescent probe for LMP7: a chemical proteomics tool for the immunoproteasome in living cells. Chembiochem (2012) 0.85
Radiation sensitivity depends on OGG1 activity status in human leukemia cell lines. Free Radic Biol Med (2002) 0.84
Structure-based design of β1i or β5i specific inhibitors of human immunoproteasomes. J Med Chem (2014) 0.84
Iron chelator induces MIP-alpha/CCL20 in human intestinal epithelial cells: implication for triggering mucosal adaptive immunity. Exp Mol Med (2005) 0.84
In vitro evidence for the recognition of 8-oxoGTP by Ras, a small GTP-binding protein. Biochem Biophys Res Commun (2005) 0.84
Impact of linker length on the activity of PROTACs. Mol Biosyst (2010) 0.83
A bright approach to the immunoproteasome: development of LMP2/β1i-specific imaging probes. Bioorg Med Chem (2011) 0.83
Iron chelator induces THP-1 cell differentiation potentially by modulating intracellular glutathione levels. Free Radic Biol Med (2006) 0.83
Increased expression of MIP-3alpha/CCL20 in peripheral blood mononuclear cells from patients with ulcerative colitis and its down-regulation by sulfasalazine and glucocorticoid treatment. Inflamm Bowel Dis (2005) 0.83
An adult case of internal mammary arterio-venous fistula. Korean Circ J (2011) 0.82
Induction of growth phase-specific autolysis in Bacillus subtilis 168 by growth inhibitors. J Microbiol (2009) 0.81
Nitric oxide production and inducible nitric oxide synthase expression induced by Prevotella nigrescens lipopolysaccharide. FEMS Immunol Med Microbiol (2005) 0.81
Jostling for position: optimizing linker location in the design of estrogen receptor-targeting PROTACs. ChemMedChem (2010) 0.81
Roles of Rac and p38 kinase in the activation of cytosolic phospholipase A2 in response to PMA. Biochem J (2005) 0.81
Axillary approach versus the infraclavicular approach in ultrasound-guided brachial plexus block: comparison of anesthetic time. Korean J Anesthesiol (2011) 0.81
An evaluation of the time for nursing activity in a hospital using a full Electronic Medical Record System (EMR). Stud Health Technol Inform (2006) 0.81
Xenoreactivity of human clonal mesenchymal stem cells in a major histocompatibility complex-matched allogeneic graft-versus-host disease mouse model. Cell Immunol (2009) 0.80
A FRET-based approach for identification of proteasome catalytic subunit composition. Mol Biosyst (2014) 0.79
Regulating charge injection in ambipolar organic field-effect transistors by mixed self-assembled monolayers. ACS Appl Mater Interfaces (2014) 0.78
Reversible electrochemical switching of polyelectrolyte brush surface energy using electroactive counterions. Langmuir (2008) 0.77
Combination effects of cation and anion of ionic liquids on the cadmium metal-organic frameworks in ionothermal systems. Inorg Chem (2008) 0.77
SAR studies of 2-methoxyestradiol and development of its analogs as probes of anti-tumor mechanisms. Bioorg Med Chem Lett (2006) 0.77
Photodynamic therapy for breast cancer in a BALB/c mouse model. J Gynecol Oncol (2012) 0.77
Nitric oxide-dependent CYP2B degradation is potentiated by a cytokine-regulated pathway and utilizes the immunoproteasome subunit LMP2. Biochem J (2012) 0.77
Assessing the translatability of in vivo cardiotoxicity mechanisms to in vitro models using causal reasoning. BMC Pharmacol Toxicol (2013) 0.77
Combined action of extracellular signal-regulated kinase and p38 kinase rescues Molt4 T cells from nitric oxide-induced apoptotic and necrotic cell death. Free Radic Biol Med (2004) 0.76
Mutation of the lbp-5 gene alters metabolic output in Caenorhabditis elegans. BMB Rep (2014) 0.75
PROTAC-induced proteolytic targeting. Methods Mol Biol (2012) 0.75
Impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cutaneous wound healing. Exp Toxicol Pathol (2011) 0.75
Elucidating the catalytic subunit composition of distinct proteasome subtypes: a crosslinking approach employing bifunctional activity-based probes. Chembiochem (2014) 0.75
Influence of phenolic hydroxyl groups on second-order optical nonlinearity at an example of 2,4- and 3,4-dihydroxyl hydrazone isomorphic crystals. J Chem Phys (2009) 0.75
Purification and characterization of a new anticoagulant protein, PP27, from placenta. Thromb Res (2005) 0.75
Effect of FGF-2 on collagen tissue regeneration by human vertebral bone marrow stem cells. Stem Cells Dev (2015) 0.75
Manganese Oxides Nanoparticle as New P-type Dopant for High Performance Polymer Field-Effect Transistors. ACS Appl Mater Interfaces (2017) 0.75
Palliation using a self-expandable stent in a patient with obstructive right-ventricular outflow tract after total correction of tetralogy of Fallot: self-expandable stent in tetralogy of Fallot. Pediatr Cardiol (2012) 0.75