Published in Arthritis Rheum on October 01, 2007
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Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling. PLoS One (2014) 1.59
Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice. Arthritis Res Ther (2012) 1.52
Bone mineral density and prevalent osteoarthritis of the hip in older men for the Osteoporotic Fractures in Men (MrOS) Study Group. Osteoporos Int (2010) 1.10
Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes. Arthritis Res Ther (2012) 1.02
Selection bias in rheumatic disease research. Nat Rev Rheumatol (2014) 1.02
Biomarkers and cytokines of bone turnover: extensive evaluation in a cohort of patients with ankylosing spondylitis. BMC Musculoskelet Disord (2012) 1.02
To Wnt or not to Wnt: the bone and joint health dilemma. Nat Rev Rheumatol (2013) 1.01
New findings in osteoarthritis pathogenesis: therapeutic implications. Ther Adv Chronic Dis (2013) 1.00
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Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. Osteoarthritis Cartilage (2012) 0.92
Dickkopf-1 (Dkk-1) in plasma and synovial fluid is inversely correlated with radiographic severity of knee osteoarthritis patients. BMC Musculoskelet Disord (2010) 0.92
Signaling pathways in cartilage repair. Int J Mol Sci (2014) 0.86
Dickkopf-1 as a novel predictor is associated with risk stratification by GRACE risk scores for predictive value in patients with acute coronary syndrome: a retrospective research. PLoS One (2013) 0.83
Osteoarthritis pathogenesis: a review of molecular mechanisms. Calcif Tissue Int (2014) 0.83
Targeting the Wnt signaling pathway to augment bone formation. Curr Osteoporos Rep (2008) 0.82
Plasma and vitreous fluid levels of Dickkopf-1 in patients with diabetic retinopathy. Eye (Lond) (2014) 0.79
What is the utility of biomarkers for assessing the pathophysiology of hip osteoarthritis? A systematic review. Clin Orthop Relat Res (2015) 0.77
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Plasma Dickkopf-related Protein 1, an antagonist of the Wnt pathway, is associated with HIV-associated neurocognitive impairment. AIDS (2017) 0.75
Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips. Calcif Tissue Int (2017) 0.75
Racial differences in associations between baseline patterns of radiographic osteoarthritis and multiple definitions of progression of hip osteoarthritis: the Johnston County Osteoarthritis Project. Arthritis Res Ther (2015) 0.75
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Changes in expression of Wnt signaling pathway inhibitors dickkopf-1 and sclerostin before and after total joint arthroplasty. Medicine (Baltimore) (2017) 0.75
Association between serum and synovial fluid Dickkopf-1 levels with radiographic severity in primary knee osteoarthritis patients. Clin Rheumatol (2017) 0.75
The Utility of Biomarkers in Osteoporosis Management. Mol Diagn Ther (2017) 0.75
Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling. PLoS One (2017) 0.75
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 41.47
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet (2012) 26.95
HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell (2003) 9.12
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
Bone-density testing interval and transition to osteoporosis in older women. N Engl J Med (2012) 5.81
High-trauma fractures and low bone mineral density in older women and men. JAMA (2007) 5.00
BMD at multiple sites and risk of fracture of multiple types: long-term results from the Study of Osteoporotic Fractures. J Bone Miner Res (2003) 4.64
Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging. Arthritis Rheum (2007) 4.06
Walking performance and cardiovascular response: associations with age and morbidity--the Health, Aging and Body Composition Study. J Gerontol A Biol Sci Med Sci (2003) 3.95
Osteoarthritis: epidemiology. Best Pract Res Clin Rheumatol (2006) 3.80
Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the health, aging, and body composition study. Arch Intern Med (2005) 3.39
A comparison of prediction models for fractures in older women: is more better? Arch Intern Med (2009) 3.37
Bone mineral density and the risk of incident nonspinal fractures in black and white women. JAMA (2005) 3.30
Meniscal tear in knees without surgery and the development of radiographic osteoarthritis among middle-aged and elderly persons: The Multicenter Osteoarthritis Study. Arthritis Rheum (2009) 3.19
Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures. J Gerontol A Biol Sci Med Sci (2007) 3.16
Long-term risk of incident vertebral fractures. JAMA (2007) 3.15
Central nervous system-active medications and risk for falls in older women. J Am Geriatr Soc (2002) 3.03
Effect of alendronate on vertebral fracture risk in women with bone mineral density T scores of-1.6 to -2.5 at the femoral neck: the Fracture Intervention Trial. Mayo Clin Proc (2005) 3.02
Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J Clin Invest (2009) 2.75
Older women with diabetes have a higher risk of falls: a prospective study. Diabetes Care (2002) 2.72
A new approach yields high rates of radiographic progression in knee osteoarthritis. J Rheumatol (2008) 2.63
Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (2004) 2.60
IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest (2004) 2.56
Retracted Induction of a homeostatic circuit in lung tissue by microbial compounds. Immunity (2006) 2.49
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum (2009) 2.47
Relationship of changes in physical activity and mortality among older women. JAMA (2003) 2.42
Hip fracture in women without osteoporosis. J Clin Endocrinol Metab (2005) 2.35
Progression of radiographic hip osteoarthritis over eight years in a community sample of elderly white women. Arthritis Rheum (2004) 2.32
Central nervous system active medications and risk for fractures in older women. Arch Intern Med (2003) 2.30
The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis Rheum (2004) 2.22
Diabetes and incidence of functional disability in older women. Diabetes Care (2002) 2.16
Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation. Arthritis Rheum (2009) 2.16
Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females. Proc Natl Acad Sci U S A (2004) 2.16
Risk for fracture in women with low serum levels of thyroid-stimulating hormone. Ann Intern Med (2001) 2.13
Intravesical Toll-like receptor 7 agonist R-837: optimization of its formulation in an orthotopic mouse model of bladder cancer. Int J Urol (2010) 2.10
ERK activation drives intestinal tumorigenesis in Apc(min/+) mice. Nat Med (2010) 2.09
A subset of Toll-like receptor ligands induces cross-presentation by bone marrow-derived dendritic cells. J Immunol (2003) 2.04
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum (2010) 2.02
Interleukin 1 receptor dependence of serum transferred arthritis can be circumvented by toll-like receptor 4 signaling. J Exp Med (2003) 1.99
Executive function, more than global cognition, predicts functional decline and mortality in elderly women. J Gerontol A Biol Sci Med Sci (2007) 1.97
Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. Radiology (2009) 1.95
Circulating 25-hydroxyvitamin D levels and frailty status in older women. J Clin Endocrinol Metab (2010) 1.93
Is a fall just a fall: correlates of falling in healthy older persons. The Health, Aging and Body Composition Study. J Am Geriatr Soc (2003) 1.93
Epidemiologic studies for osteoarthritis: new versus conventional study design approaches. Rheum Dis Clin North Am (2004) 1.90
The association between sleep duration and obesity in older adults. Int J Obes (Lond) (2008) 1.89
Vision impairment and combined vision and hearing impairment predict cognitive and functional decline in older women. J Am Geriatr Soc (2004) 1.88
Mobility limitation in self-described well-functioning older adults: importance of endurance walk testing. J Gerontol A Biol Sci Med Sci (2008) 1.84
Long-term prediction of incident hip fracture risk in elderly white women: study of osteoporotic fractures. J Am Geriatr Soc (2004) 1.84
Objective physical activity measurement in the osteoarthritis initiative: Are guidelines being met? Arthritis Rheum (2011) 1.81
What proportion of incident radiographic vertebral deformities is clinically diagnosed and vice versa? J Bone Miner Res (2005) 1.76
Physical activity over the life course and its association with cognitive performance and impairment in old age. J Am Geriatr Soc (2010) 1.76
Comparison of sleep parameters from actigraphy and polysomnography in older women: the SOF study. Sleep (2008) 1.75
The last 2 years of life: functional trajectories of frail older people. J Am Geriatr Soc (2003) 1.74
Greater trochanteric pain syndrome: epidemiology and associated factors. Arch Phys Med Rehabil (2007) 1.72
The lateral view radiograph for assessment of the tibiofemoral joint space in knee osteoarthritis: its reliability, sensitivity to change, and longitudinal validity. Arthritis Rheum (2005) 1.72
Intentional and unintentional weight loss increase bone loss and hip fracture risk in older women. J Am Geriatr Soc (2003) 1.72
The KRN mouse model of inflammatory arthritis. Springer Semin Immunopathol (2003) 1.67
The role of natural antibodies in atherogenesis. J Lipid Res (2005) 1.65
Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: The Health, Aging, and Body Composition Study. J Bone Miner Res (2004) 1.64
Recent advances in osteoarthritis imaging--the osteoarthritis initiative. Nat Rev Rheumatol (2012) 1.64
Presence of MRI-detected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study. Ann Rheum Dis (2011) 1.63
Platelet-derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast-like synoviocytes. Arthritis Res Ther (2010) 1.59
Estimates of the proportion of older white women who would be recommended for pharmacologic treatment by the new U.S. National Osteoporosis Foundation Guidelines. J Bone Miner Res (2009) 1.58
Overweight and obesity over the adult life course and incident mobility limitation in older adults: the health, aging and body composition study. Am J Epidemiol (2009) 1.52
Daily walking and the risk of incident functional limitation in knee osteoarthritis: an observational study. Arthritis Care Res (Hoboken) (2014) 1.50
Lower serum albumin concentration and change in muscle mass: the Health, Aging and Body Composition Study. Am J Clin Nutr (2005) 1.49
Patellar cartilage: T2 values and morphologic abnormalities at 3.0-T MR imaging in relation to physical activity in asymptomatic subjects from the osteoarthritis initiative. Radiology (2009) 1.47
Reliability and validity of the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale in older men. J Gerontol A Biol Sci Med Sci (2011) 1.46
Longitudinal study of changes in hip bone mineral density in Caucasian and African-American women. J Am Geriatr Soc (2005) 1.46
TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice. J Clin Invest (2010) 1.45
Mild cognitive impairment, dementia, and their subtypes in oldest old women. Arch Neurol (2011) 1.45
The JAK inhibitor CP-690,550 (tofacitinib) inhibits TNF-induced chemokine expression in fibroblast-like synoviocytes: autocrine role of type I interferon. Ann Rheum Dis (2011) 1.42
The association of proximal femoral shape and incident radiographic hip OA in elderly women. Osteoarthritis Cartilage (2009) 1.41
Prediction of mortality in community-living frail elderly people with long-term care needs. J Am Geriatr Soc (2007) 1.40
Lipid-lowering drug use and breast cancer in older women: a prospective study. J Womens Health (Larchmt) (2003) 1.39
Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. J Immunol (2009) 1.39
Hyperkyphosis predicts mortality independent of vertebral osteoporosis in older women. Ann Intern Med (2009) 1.38
Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: findings from the Multicenter Osteoarthritis Study and the Osteoarthritis Initiative. Arthritis Rheum (2013) 1.37
Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis. Proc Natl Acad Sci U S A (2006) 1.37
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas. Oncogene (2002) 1.37
Meniscal pathology on MRI increases the risk for both incident and enlarging subchondral bone marrow lesions of the knee: the MOST Study. Ann Rheum Dis (2010) 1.36
Very low prevalence of hip osteoarthritis among Chinese elderly in Beijing, China, compared with whites in the United States: the Beijing osteoarthritis study. Arthritis Rheum (2002) 1.36
Conventional dendritic cells regulate the outcome of colonic inflammation independently of T cells. Proc Natl Acad Sci U S A (2007) 1.35
Assessment of synovitis with contrast-enhanced MRI using a whole-joint semiquantitative scoring system in people with, or at high risk of, knee osteoarthritis: the MOST study. Ann Rheum Dis (2010) 1.35
Diabetes and bone loss at the hip in older black and white adults. J Bone Miner Res (2004) 1.33
The effects of impaired joint position sense on the development and progression of pain and structural damage in knee osteoarthritis. Arthritis Rheum (2009) 1.33
Repression of beta-catenin function in malignant cells by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A (2005) 1.32
Lumbar spine listhesis in older African American women. Spine J (2003) 1.32
Women who maintain optimal cognitive function into old age. J Am Geriatr Soc (2007) 1.31
IFN-alpha beta promote priming of antigen-specific CD8+ and CD4+ T lymphocytes by immunostimulatory DNA-based vaccines. J Immunol (2002) 1.30
Trajectories of gait speed predict mortality in well-functioning older adults: the Health, Aging and Body Composition study. J Gerontol A Biol Sci Med Sci (2012) 1.29