Charles Spruck

Author PubWeight™ 16.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 FBXW7/hCDC4 is a general tumor suppressor in human cancer. Cancer Res 2007 3.79
2 Control of iron homeostasis by an iron-regulated ubiquitin ligase. Science 2009 2.60
3 The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling. Cancer Res 2007 1.85
4 The Fbxw7/hCdc4 tumor suppressor in human cancer. Cancer Lett 2008 1.35
5 Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis. EMBO J 2007 1.29
6 Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer. Breast Cancer Res 2010 1.01
7 CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer. EMBO Mol Med 2013 0.99
8 SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis. Exp Cell Res 2008 0.98
9 Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress response. Mol Cell 2013 0.87
10 Development and validation of a method for profiling post-translational modification activities using protein microarrays. PLoS One 2010 0.83
11 PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer. Cancer Res 2014 0.78