Published in J Nat Prod on October 03, 2007
New peptides isolated from Lyngbya species: a review. Mar Drugs (2010) 1.24
Phylogenetic and chemical diversity of three chemotypes of bloom-forming lyngbya species (Cyanobacteria: Oscillatoriales) from reefs of southeastern Florida. Appl Environ Microbiol (2009) 1.17
Chemodiversity in freshwater and terrestrial cyanobacteria - a source for drug discovery. Curr Drug Targets (2011) 1.15
Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. J Med Chem (2009) 1.09
Antineoplastic agents. 570. Isolation and structure elucidation of bacillistatins 1 and 2 from a marine Bacillus silvestris. J Nat Prod (2009) 1.06
Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena. Mar Drugs (2009) 1.01
Grassypeptolides A-C, cytotoxic bis-thiazoline containing marine cyclodepsipeptides. J Org Chem (2010) 0.93
Largamides A-C, tiglic acid-containing cyclodepsipeptides with elastase-inhibitory activity from the marine cyanobacterium Lyngbya confervoides. Planta Med (2009) 0.93
Biological targets and mechanisms of action of natural products from marine cyanobacteria. Nat Prod Rep (2015) 0.90
Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. J Med Chem (2013) 0.89
Cyclic depsipeptides, grassypeptolides D and E and Ibu-epidemethoxylyngbyastatin 3, from a Red Sea Leptolyngbya cyanobacterium. J Nat Prod (2011) 0.88
Tiglicamides A-C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides. Phytochemistry (2009) 0.88
A surprising mechanistic "switch" in Lewis acid activation: a bifunctional, asymmetric approach to alpha-hydroxy acid derivatives. J Am Chem Soc (2008) 0.87
Marine cyanobacteria compounds with anticancer properties: a review on the implication of apoptosis. Mar Drugs (2012) 0.85
Stigonemapeptin, an Ahp-containing depsipeptide with elastase inhibitory activity from the bloom-forming freshwater cyanobacterium Stigonema sp. J Nat Prod (2012) 0.83
Intramolecular modulation of serine protease inhibitor activity in a marine cyanobacterium with antifeedant properties. Mar Drugs (2010) 0.80
Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lyngbyastatin 7 and in Vitro Biological Evaluation in Model Systems for Pulmonary Diseases. J Org Chem (2015) 0.78
Exploring marine cyanobacteria for lead compounds of pharmaceutical importance. ScientificWorldJournal (2012) 0.78
α,β-Dehydroamino acids in naturally occurring peptides. Amino Acids (2014) 0.78
Depsipeptides from a Guamanian Marine Cyanobacterium, Lyngbya bouillonii, with Selective Inhibition of Serine Proteases. Tetrahedron Lett (2010) 0.78
"Head-to-side-chain" cyclodepsipeptides of marine origin. Mar Drugs (2013) 0.77
Anti-inflammatory effects of secondary metabolites of marine Pseudomonas sp. in human neutrophils are through inhibiting P38 MAPK, JNK, and calcium pathways. PLoS One (2014) 0.77
Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium. Bioorg Med Chem (2016) 0.75
Tiny Microbes with a Big Impact: The Role of Cyanobacteria and Their Metabolites in Shaping Our Future. Mar Drugs (2016) 0.75
Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer. Mar Drugs (2017) 0.75
Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp. J Am Chem Soc (2008) 2.34
Design, construction, and validation of a 1-mm triple-resonance high-temperature-superconducting probe for NMR. J Magn Reson (2006) 2.32
Climate change: links to global expansion of harmful cyanobacteria. Water Res (2011) 2.14
Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure-activity relationships. J Nat Prod (2011) 1.81
Total synthesis and molecular target of largazole, a histone deacetylase inhibitor. J Am Chem Soc (2008) 1.76
A small-molecule inducer of the antioxidant response element. Chem Biol (2010) 1.65
Marine natural products: a new wave of drugs? Future Med Chem (2011) 1.57
Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression. Nat Cell Biol (2010) 1.47
A genomic screen for activators of the antioxidant response element. Proc Natl Acad Sci U S A (2007) 1.44
Identity, regulation, and activity of inducible diterpenoid phytoalexins in maize. Proc Natl Acad Sci U S A (2011) 1.33
Lyngbyastatin 4, a dolastatin 13 analogue with elastase and chymotrypsin inhibitory activity from the marine cyanobacterium Lyngbya confervoides. J Nat Prod (2007) 1.32
Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation. Mol Pharmacol (2009) 1.28
Apratoxin E, a cytotoxic peptolide from a guamanian collection of the marine cyanobacterium Lyngbya bouillonii. J Nat Prod (2008) 1.28
Diversity and dynamics of bacterial communities in early life stages of the Caribbean coral Porites astreoides. ISME J (2011) 1.28
Isolation and biological evaluation of 8-epi-malyngamide C from the Floridian marine cyanobacterium Lyngbya majuscula. J Nat Prod (2010) 1.27
New apratoxins of marine cyanobacterial origin from Guam and Palau. Bioorg Med Chem (2002) 1.24
Clinical, hormonal and cytogenetic evaluation of 46,XX males and review of the literature. J Pediatr Endocrinol Metab (2005) 1.24
Morphological, chemical, and genetic diversity of tropical marine cyanobacteria Lyngbya spp. and Symploca spp. (Oscillatoriales). Appl Environ Microbiol (2004) 1.19
Coral-associated micro-organisms and their roles in promoting coral health and thwarting diseases. Proc Biol Sci (2013) 1.18
Biogeography of sponge chemical ecology: comparisons of tropical and temperate defenses. Oecologia (2003) 1.18
Phylogenetic and chemical diversity of three chemotypes of bloom-forming lyngbya species (Cyanobacteria: Oscillatoriales) from reefs of southeastern Florida. Appl Environ Microbiol (2009) 1.17
Carriebowmide, a new cyclodepsipeptide from the marine cyanobacterium Lyngbya polychroa. J Nat Prod (2008) 1.16
Single insect NMR: A new tool to probe chemical biodiversity. ACS Chem Biol (2006) 1.15
Lyngbyaloside B, a new glycoside macrolide from a Palauan marine cyanobacterium, Lyngbya sp. J Nat Prod (2002) 1.15
Atypical serum immunofixation patterns frequently emerge in immunomodulatory therapy and are associated with a high degree of response in multiple myeloma. Br J Haematol (2008) 1.14
Combinatorial strategies by marine cyanobacteria: symplostatin 4, an antimitotic natural dolastatin 10/15 hybrid that synergizes with the coproduced HDAC inhibitor largazole. Chembiochem (2009) 1.14
Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium Lyngbya bouillonii from Guam. J Nat Prod (2010) 1.13
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor. J Pharmacol Exp Ther (2010) 1.13
Macroalgal extracts induce bacterial assemblage shifts and sublethal tissue stress in Caribbean corals. PLoS One (2012) 1.10
Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. J Med Chem (2009) 1.09
Ecological functions of tetrodotoxin in a deadly polyclad flatworm. Proc Natl Acad Sci U S A (2006) 1.07
Synthesis and activity of largazole analogues with linker and macrocycle modification. Org Lett (2008) 1.07
Molassamide, a depsipeptide serine protease inhibitor from the marine cyanobacterium Dichothrix utahensis. J Nat Prod (2010) 1.06
Total structure determination of grassypeptolide, a new marine cyanobacterial cytotoxin. Org Lett (2008) 1.06
Bacterial acquisition in juveniles of several broadcast spawning coral species. PLoS One (2010) 1.05
Largazole: from discovery to broad-spectrum therapy. Nat Prod Rep (2012) 1.03
Novel acidic sesquiterpenoids constitute a dominant class of pathogen-induced phytoalexins in maize. Plant Physiol (2011) 1.03
Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity. ACS Med Chem Lett (2011) 1.02
Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena. Mar Drugs (2009) 1.01
A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life. Proc Natl Acad Sci U S A (2010) 0.98
Chemical deterrence of a cyanobacterial metabolite against generalized and specialized grazers. J Chem Ecol (2006) 0.97
Marine chemical ecology in benthic environments. Nat Prod Rep (2014) 0.97
Lyngbyoic acid, a "tagged" fatty acid from a marine cyanobacterium, disrupts quorum sensing in Pseudomonas aeruginosa. Mol Biosyst (2011) 0.97
Inhibition of marine biofouling by bacterial quorum sensing inhibitors. Biofouling (2011) 0.95
Total synthesis and biological evaluation of grassypeptolide A. Chemistry (2013) 0.95
Cytotoxic xanthone-anthraquinone heterodimers from an unidentified fungus of the order Hypocreales (MSX 17022). J Antibiot (Tokyo) (2011) 0.95
Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp. J Nat Prod (2008) 0.94
Phylogenetic inferences reveal a large extent of novel biodiversity in chemically rich tropical marine cyanobacteria. Appl Environ Microbiol (2013) 0.94
Palatability of macroalgae that use different types of chemical defenses. J Chem Ecol (2006) 0.94
Symplostatin 3, a new dolastatin 10 analogue from the marine cyanobacterium Symploca sp. VP452. J Nat Prod (2002) 0.94
Grassypeptolides A-C, cytotoxic bis-thiazoline containing marine cyclodepsipeptides. J Org Chem (2010) 0.93
Largamides A-C, tiglic acid-containing cyclodepsipeptides with elastase-inhibitory activity from the marine cyanobacterium Lyngbya confervoides. Planta Med (2009) 0.93
The molecular pharmacology of symplostatin 1: a new antimitotic dolastatin 10 analog. Int J Cancer (2003) 0.93
(S)-4,5-dihydro-2-(2-hydroxy-4-hydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid polyethers: a solution to nephrotoxicity. J Med Chem (2006) 0.93
The isolation and structure elucidation of Tasiamide B, a 4-amino-3-hydroxy-5-phenylpentanoic acid containing peptide from the marine Cyanobacterium Symploca sp. J Nat Prod (2003) 0.92
Caylobolide B, a macrolactone from symplostatin 1-producing marine cyanobacteria Phormidium spp. from Florida. J Nat Prod (2010) 0.92
Minor activities and transition state properties of the human steroid hydroxylases cytochromes P450c17 and P450c21, from reactions observed with deuterium-labeled substrates. Biochemistry (2012) 0.92
Malyngolide from the cyanobacterium Lyngbya majuscula interferes with quorum sensing circuitry. Environ Microbiol Rep (2010) 0.92
Cyanobacterial peptides as a prototype for the design of potent β-secretase inhibitors and the development of selective chemical probes for other aspartic proteases. J Med Chem (2012) 0.92
Pitiprolamide, a proline-rich dolastatin 16 analogue from the marine cyanobacterium Lyngbya majuscula from Guam. J Nat Prod (2010) 0.92
Seaweed extracts and unsaturated fatty acid constituents from the green alga Ulva lactuca as activators of the cytoprotective Nrf2-ARE pathway. Free Radic Biol Med (2013) 0.91
Ulongamides A-F, new beta-amino acid-containing cyclodepsipeptides from Palauan collections of the marine cyanobacterium Lyngbya sp. J Nat Prod (2002) 0.91
Ulongapeptin, a cytotoxic cyclic depsipeptide from a Palauan marine cyanobacterium Lyngbya sp. J Nat Prod (2003) 0.91
Tasiamide, a cytotoxic peptide from the marine cyanobacterium Symploca sp. J Nat Prod (2002) 0.90
Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses. Free Radic Biol Med (2009) 0.90
Biological targets and mechanisms of action of natural products from marine cyanobacteria. Nat Prod Rep (2015) 0.90
Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. J Med Chem (2013) 0.89
Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues. J Nat Prod (2011) 0.89
Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium Lyngbya confervoides. J Nat Prod (2002) 0.88
Tiglicamides A-C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides. Phytochemistry (2009) 0.88
Dragonamides C and D, linear lipopeptides from the marine cyanobacterium brown Lyngbya polychroa. J Nat Prod (2008) 0.88
Caldora penicillata gen. nov., comb. nov. (cyanobacteria), a pantropical marine species with biomedical relevance. J Phycol (2015) 0.88
Steroid profiling by gas chromatography-mass spectrometry and high performance liquid chromatography-mass spectrometry for adrenal diseases. Horm Cancer (2011) 0.87