Published in J Korean Med Sci on September 01, 2007
Sensitive Melting Analysis after Real Time- Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection. Nucleic Acids Res (2008) 1.57
Epigenetics of lung cancer. Transl Res (2014) 0.95
Association between P(16INK4a) promoter methylation and non-small cell lung cancer: a meta-analysis. PLoS One (2013) 0.88
CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer. J Thorac Oncol (2013) 0.86
Cytological examination of pleural cavity lavage accompanied by the study of gene promoter hypermethylation of p16 and O6-methylguanine-DNA-methyltransferase genes in diagnostics of non-small cell lung cancer metastatic changes into pleura. Contemp Oncol (Pozn) (2012) 0.81
Hypermethylation of CCND2 May Reflect a Smoking-Induced Precancerous Change in the Lung. J Oncol (2011) 0.79
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc Natl Acad Sci U S A (1992) 29.51
MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res (2000) 9.30
Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res (1998) 8.95
A gene hypermethylation profile of human cancer. Cancer Res (2001) 8.93
Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res (1977) 4.59
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma. Cancer Res (1996) 3.18
A quantitative HpaII-PCR assay to measure methylation of DNA from a small number of cells. Nucleic Acids Res (1990) 2.81
De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase. Mol Cell Biol (1996) 2.26
Neoplastic characteristics of the DNA found in the plasma of cancer patients. Oncology (1989) 2.03
p16(INK4a) and histology-specific methylation of CpG islands by exposure to tobacco smoke in non-small cell lung cancer. Cancer Res (2001) 1.88
Formation of methylation patterns in the mammalian genome. Mutat Res (1997) 1.88
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer. Proc Natl Acad Sci U S A (1996) 1.76
Gene promoter hypermethylation in tumors and lymph nodes of stage I lung cancer patients. Clin Cancer Res (2003) 1.65
p16INK4A and CDH13 hypermethylation in tumor and serum of non-small cell lung cancer patients. J Cell Physiol (2006) 1.32
DNA methylation in genomic imprinting, development, and disease. J Pathol (2001) 1.31
Hypermethylation of RASSF1A promoter is associated with the age at starting smoking and a poor prognosis in primary non-small cell lung cancer. Cancer Res (2003) 1.29
Molecular and genetic aspects of lung cancer. Am J Respir Crit Care Med (2000) 1.17
Epigenetic programming of differential gene expression in development and evolution. Dev Genet (1995) 1.12
Detection of p16 hypermethylation in circulating plasma DNA of non-small cell lung cancer patients. Cancer Lett (2002) 1.11
Aberrant p16 promoter methylation in smokers and former smokers with nonsmall cell lung cancer. Int J Cancer (2003) 1.09
The study of p16 and p15 gene methylation in head and neck squamous cell carcinoma and their quantitative evaluation in plasma by real-time PCR. Eur J Cancer (2003) 1.02
Hypermethylation of p16INK4a in Chinese lung cancer patients: biological and clinical implications. Carcinogenesis (2003) 0.98
Molecular detection of p16 promoter methylation in the serum of recurrent colorectal cancer patients. Int J Cancer (2003) 0.85
Methylation, gene expression and the chromatin connection in cancer (review) Int J Mol Med (1999) 0.84
High prevalence of antimicrobial resistance among clinical Streptococcus pneumoniae isolates in Asia (an ANSORP study). Antimicrob Agents Chemother (2004) 2.41
Recurrence of pulmonary carcinoid tumors after resection: implications for postoperative surveillance. Ann Thorac Surg (2013) 2.25
A randomized, clinical trial of frozen versus standard nasogastric tube placement. World J Surg (2009) 2.03
Clinical significance of preoperative neutrophil-lymphocyte versus platelet-lymphocyte ratio in patients with operable colorectal cancer. Biomarkers (2012) 2.00
An electrically pumped polariton laser. Nature (2013) 1.68
Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death. Brain (2008) 1.65
Quantum-dot spin-photon entanglement via frequency downconversion to telecom wavelength. Nature (2012) 1.54
[Assessment of factors affecting the accuracy of endoscopic ultrasonography in T2 stage gastric cancer]. Korean J Gastroenterol (2008) 1.51
Effects of renin-angiotensin system inhibitors on the occurrence of acute kidney injury following off-pump coronary artery bypass grafting. Circ J (2010) 1.49
A cut above the rest: targeted genome editing technologies in human pluripotent stem cells. J Biol Chem (2013) 1.47
Evaluation of liver and thyroid toxicity in Sprague-Dawley rats after exposure to polybrominated diphenyl ether BDE-209. J Toxicol Sci (2010) 1.46
Hepatitis a in Korea: epidemiological shift and call for vaccine strategy. Intervirology (2008) 1.39
Clinical significance of preoperative serum vascular endothelial growth factor, interleukin-6, and C-reactive protein level in colorectal cancer. BMC Cancer (2010) 1.31
Effect of crude saponin of Korean red ginseng on high-fat diet-induced obesity in the rat. J Pharmacol Sci (2005) 1.29
Prevalence and clinical characteristics of the metabolic syndrome in middle-aged Korean adults. Korean J Intern Med (2005) 1.25
Preoperative staging of gastric cancer by endoscopic ultrasonography and multidetector-row computed tomography. J Gastroenterol Hepatol (2010) 1.23
Forkhead box M1 expression in pulmonary squamous cell carcinoma: correlation with clinicopathologic features and its prognostic significance. Hum Pathol (2009) 1.16
A highly sensitive and selective diagnostic assay based on virus nanoparticles. Nat Nanotechnol (2009) 1.15
The water-soluble fraction of bee venom produces antinociceptive and anti-inflammatory effects on rheumatoid arthritis in rats. Life Sci (2002) 1.15
Workfunction-tunable, N-doped reduced graphene transparent electrodes for high-performance polymer light-emitting diodes. ACS Nano (2011) 1.14
Effects of intrathecal dexmedetomidine on low-dose bupivacaine spinal anesthesia in elderly patients undergoing transurethral prostatectomy. Biol Pharm Bull (2013) 1.13
Role of the RAM network in cell polarity and hyphal morphogenesis in Candida albicans. Mol Biol Cell (2008) 1.13
Clinical characteristics of ovarian teratoma: age-focused retrospective analysis of 580 cases. Am J Obstet Gynecol (2011) 1.11
Three new dammarane glycosides from heat processed ginseng. Arch Pharm Res (2002) 1.05
The isolation and antioxidative effects of vitexin from Acer palmatum. Arch Pharm Res (2005) 1.05
Tumor-homing poly-siRNA/glycol chitosan self-cross-linked nanoparticles for systemic siRNA delivery in cancer treatment. Angew Chem Int Ed Engl (2012) 1.04
Pulmonary paraganglioma manifesting as an endobronchial mass. Korean J Radiol (2008) 1.03
Expression of microRNA miR-126 and miR-200c is associated with prognosis in patients with non-small cell lung cancer. Virchows Arch (2014) 1.02
Blood mercury concentration and related factors in an urban coastal area in Korea. J Prev Med Public Health (2010) 1.00
Genetic diversity among Korean bermudagrass (Cynodon spp.) ecotypes characterized by morphological, cytological and molecular approaches. Mol Cells (2008) 0.99
Microglial Toll-like receptor 2 contributes to kainic acid-induced glial activation and hippocampal neuronal cell death. J Biol Chem (2010) 0.99
RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system. J Control Release (2010) 0.97
[Regional difference of antibiotic resistance of helicobacter pylori strains in Korea]. Korean J Gastroenterol (2011) 0.97
Potential prognostic significance of p185(HER2) overexpression with loss of PTEN expression in gastric carcinomas. Tumori (2006) 0.96
[Diagnosis of gastroesophageal reflux disease: a systematic review]. Korean J Gastroenterol (2010) 0.94
Facile synthesis of monodispersed mesoporous silica nanoparticles with ultralarge pores and their application in gene delivery. ACS Nano (2011) 0.93
Altered expression of microRNA miR-21, miR-155, and let-7a and their roles in pulmonary neuroendocrine tumors. Pathol Int (2012) 0.93
Direct synthesis of polymer nanocapsules with a noncovalently tailorable surface. Angew Chem Int Ed Engl (2007) 0.93
Clinicopathological significance of p53, hypoxia-inducible factor 1alpha, and vascular endothelial growth factor expression in colorectal cancer. Anticancer Res (2010) 0.93
Three-dimensional shape engineered, interfacial gelation of reduced graphene oxide for high rate, large capacity supercapacitors. Adv Mater (2013) 0.92
Lipid production in Porphyridium cruentum grown under different culture conditions. J Biosci Bioeng (2009) 0.92
Canaliculitis with a papilloma-like mass caused by a temporary punctal plug. Ophthal Plast Reconstr Surg (2009) 0.91
Phase I study of autologous dendritic cell tumor vaccine in patients with non-small cell lung cancer. Lung Cancer (2010) 0.89
Inhibition of COX-2 activity and proinflammatory cytokines (TNF-alpha and IL-1beta) production by water-soluble sub-fractionated parts from bee (Apis mellifera) venom. Arch Pharm Res (2003) 0.89
Involvement of IL-10 gene promoter polymorphisms in the susceptibility for childhood asthma. Lung (2011) 0.88
Autoimmune hemolytic anemia in a patient with primary ovarian non-Hodgkin's lymphoma. J Korean Med Sci (2004) 0.88
The association between the DRD2 TaqI A polymorphism and smoking cessation in response to acupuncture in Koreans. J Altern Complement Med (2005) 0.88
Involvement of the MAPK and PI3K pathways in chitinase 3-like 1-regulated hyperoxia-induced airway epithelial cell death. Biochem Biophys Res Commun (2012) 0.88
Four new acetylated ginsenosides from processed ginseng (sun ginseng). Arch Pharm Res (2002) 0.88
Characterization of deletions in the DYS385 flanking region and null alleles associated with AZFc microdeletions in Koreans. J Forensic Sci (2008) 0.87
A different TRAP220 expression in distinct histologic subtypes of lung adenocarcinoma and the prognostic significance. Lung Cancer (2010) 0.87
Loss of Med1/TRAP220 promotes the invasion and metastasis of human non-small-cell lung cancer cells by modulating the expression of metastasis-related genes. Cancer Lett (2012) 0.87
Radioresistant cancer cells can be conditioned to enter senescence by mTOR inhibition. Cancer Res (2013) 0.87
[Safety and efficacy of endoscopic retrograde cholangiopancreatograpy in very elderly patients]. Korean J Gastroenterol (2011) 0.87
Efficient functional delivery of siRNA using mesoporous silica nanoparticles with ultralarge pores. Small (2012) 0.87
The new 2011 international association for the study of lung cancer/american thoracic society/european respiratory society classification of lung adenocarcinoma in resected specimens: clinicopathologic relevance and emerging issues. Korean J Pathol (2013) 0.86
The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men. J Korean Med Sci (2004) 0.86
Rapid direct PCR for ABO blood typing. J Forensic Sci (2010) 0.86
Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA. Biomaterials (2011) 0.86
Substantial role of locus coeruleus-noradrenergic activation and capsaicin-insensitive primary afferent fibers in bee venom's anti-inflammatory effect. Neurosci Res (2006) 0.86
Third-line docetaxel chemotherapy for recurrent and metastatic gastric cancer. Korean J Intern Med (2013) 0.86
[Comparison between conventional 4 L polyethylene glycol and combination of 2 L polyethylene glycol and sodium phosphate solution as colonoscopy preparation]. Korean J Gastroenterol (2010) 0.85
Growth kinetics of human mesenchymal stem cells from bone marrow and umbilical cord blood. Acta Haematol (2004) 0.85
Urinary vitamin D-binding protein is elevated in patients with endometriosis. Hum Reprod (2011) 0.85
Biochemical characterization of eight genetic variants of human DNA polymerase κ involved in error-free bypass across bulky N(2)-guanyl DNA adducts. Chem Res Toxicol (2014) 0.85
Women with multiple implantation failures and recurrent pregnancy losses have increased peripheral blood T cell activation. Am J Reprod Immunol (2010) 0.85
Differential expression of forkhead box M1 and its downstream cyclin-dependent kinase inhibitors p27(kip1) and p21(waf1/cip1) in the diagnosis of pulmonary neuroendocrine tumours. Histopathology (2012) 0.85
Interobserver variability in diagnosing high-grade neuroendocrine carcinoma of the lung and comparing it with the morphometric analysis. Korean J Pathol (2012) 0.85
Development and validation of a simple index system to predict nonalcoholic fatty liver disease. Korean J Hepatol (2011) 0.84
Formation of core/shell nanoparticles with a lipid core and their application as a drug delivery system. Biomacromolecules (2005) 0.84
Clinicopathological significance of nuclear factor-kappa B, HIF-1 alpha, and vascular endothelial growth factor expression in stage III colorectal cancer. Cancer Sci (2010) 0.84
The effects of temperature on heat-related illness according to the characteristics of patients during the summer of 2012 in the Republic of Korea. J Prev Med Public Health (2013) 0.84
Effect of Mycoplasma pneumoniae lysate on interleukin-8 gene expression in human respiratory epithelial cells. Chest (2005) 0.84
Pharmacokinetic characteristics of capsaicin-loaded nanoemulsions fabricated with alginate and chitosan. J Agric Food Chem (2013) 0.84
Mitochondria DNA polymorphisms are associated with susceptibility to endometriosis. DNA Cell Biol (2011) 0.84
Molecular cloning, expression, and characterization of cathepsin L from mud loach (Misgurnus mizolepis). Appl Biochem Biotechnol (2010) 0.84
F2L, a peptide derived from heme-binding protein, inhibits LL-37-induced cell proliferation and tube formation in human umbilical vein endothelial cells. FEBS Lett (2007) 0.83
Simple and highly effective DNA extraction methods from old skeletal remains using silica columns. Forensic Sci Int Genet (2010) 0.83
Novel LMNA gene mutation in a patient with Atypical Werner's Syndrome. Korean J Intern Med (2009) 0.83
Fascin immunoreactivity for preoperatively predicting lymph node metastases in peripheral adenocarcinoma of the lung 3 cm or less in diameter. Eur J Cardiothorac Surg (2006) 0.83
Discrepancies between primary physician practice and treatment guidelines for Helicobacter pylori infection in Korea. World J Gastroenterol (2006) 0.82
Calcium-calmodulin mediates house dust mite-induced ERK activation and IL-8 production in human respiratory epithelial cells. Respiration (2007) 0.82
Comparison of cadherin-17 expression between primary colorectal adenocarcinomas and their corresponding metastases: the possibility of a diagnostic marker for detecting the primary site of metastatic tumour. Histopathology (2011) 0.82
Structural basis for ovarian tumor domain-containing protein 1 (OTU1) binding to p97/valosin-containing protein (VCP). J Biol Chem (2014) 0.82
Morphologic analysis of pulmonary neuroendocrine tumors. Korean J Pathol (2013) 0.82
Fluorescent ferritin nanoparticles and application to the aptamer sensor. Anal Chem (2011) 0.82
Effects of torsemide on pharmacodynamics and pharmacokinetics of warfarin in humans and rats. J Pharm Pharmacol (2013) 0.82
Design and evaluation of levodopa methyl ester intranasal delivery systems. J Parkinsons Dis (2011) 0.81
Cloning, site-directed mutagenesis and expression of cathepsin L-like cysteine protease from Uronema marinum (Ciliophora: Scuticociliatida). Mol Biochem Parasitol (2007) 0.81
Oxygen/Glucose Deprivation and Reperfusion Cause Modifications of Postsynaptic Morphology and Activity in the CA3 Area of Organotypic Hippocampal Slice Cultures. Korean J Physiol Pharmacol (2012) 0.81
Establishment of hepatic and neural differentiation platforms of Wilson's disease specific induced pluripotent stem cells. Protein Cell (2012) 0.81
Molecular cloning, mRNA expression and enzymatic characterization of cathepsin F from olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol (2009) 0.81
Cancer of unknown primary finally revealed to be a metastatic prostate cancer: a case report. Cancer Res Treat (2009) 0.81
Comparing of the results between single port and three ports in laparoscopic cholecystectomy. Hepatogastroenterology (2012) 0.81
Decreased glucocorticoid binding affinity to glucocorticoid receptor is important in the poor response to steroid therapy of older-aged patients with severe bronchial asthma. Allergy Asthma Proc (2003) 0.81
Think modular: a simple apoferritin-based platform for the multifaceted detection of pancreatic cancer. ACS Nano (2013) 0.81