Published in Int J Cancer on October 10, 2003
Quantitative analysis of DNA methylation profiles in lung cancer identifies aberrant DNA methylation of specific genes and its association with gender and cancer risk factors. Cancer Res (2009) 1.84
DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update. Mol Cancer (2008) 1.55
Molecular biology of lung cancer: clinical implications. Clin Chest Med (2011) 1.47
Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. Mol Cell Biol (2007) 1.31
Gene-environment interaction in tobacco-related cancers. Carcinogenesis (2008) 1.12
Therapeutic targets in the ARF tumor suppressor pathway. Curr Med Chem (2007) 1.03
Genomic impact of cigarette smoke, with application to three smoking-related diseases. Crit Rev Toxicol (2012) 1.00
Meta-analyses of gene methylation and smoking behavior in non-small cell lung cancer patients. Sci Rep (2015) 0.98
Methylation of the p16(INK4a) promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells. Oncogene (2006) 0.97
p16(INK4a) suppression by glucose restriction contributes to human cellular lifespan extension through SIRT1-mediated epigenetic and genetic mechanisms. PLoS One (2011) 0.94
Hypermethylation of p16INK4a in Korean non-small cell lung cancer patients. J Korean Med Sci (2007) 0.86
CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer. J Thorac Oncol (2013) 0.86
Methylation of the DLEC1 gene correlates with poor prognosis in Japanese lung cancer patients. Oncol Lett (2010) 0.85
Detection of methylation of the RAR-β gene in patients with non-small cell lung cancer. Oncol Lett (2011) 0.78
Long-term exposure to hexavalent chromium inhibits expression of tumor suppressor genes in cultured cells and in mice. J Trace Elem Med Biol (2012) 0.78
Correlation between smoking history and molecular pathways in sporadic colorectal cancer: a meta-analysis. Int J Clin Exp Med (2015) 0.78
Role of p14(ARF) and p15(INK4B) promoter methylation in patients with lung cancer: a systematic meta-analysis. Onco Targets Ther (2016) 0.77
Identification of DLC-1 expression and methylation status in patients with non-small-cell lung cancer. Mol Clin Oncol (2015) 0.75
Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk. Carcinogenesis (2002) 1.73
Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer. Cancer Genet Cytogenet (2004) 1.54
Air pollution and cancer: biomarker studies in human populations. Carcinogenesis (2005) 1.54
CDK4 is a probable target gene in a novel amplicon at 12q13.3-q14.1 in lung cancer. Genes Chromosomes Cancer (2005) 1.38
Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array. Oncogene (2002) 1.38
Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors. Am J Pathol (2004) 1.37
Occupational exposure to inhalable wood dust in the member states of the European Union. Ann Occup Hyg (2006) 1.29
CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis. Carcinogenesis (2003) 1.28
The association between obesity and the prevalence of low back pain in young adults: the Cardiovascular Risk in Young Finns Study. Am J Epidemiol (2008) 1.16
Gene expression profiles in asbestos-exposed epithelial and mesothelial lung cell lines. BMC Genomics (2007) 1.12
Methylation of cytochrome P4501A1 promoter in the lung is associated with tobacco smoking. Cancer Res (2003) 1.07
CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions. Biomarkers (2005) 1.02
The role of obesity and physical activity in non-specific and radiating low back pain: the Young Finns study. Semin Arthritis Rheum (2012) 1.00
Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer. Genes Chromosomes Cancer (2011) 0.99
Spindle cell tumours of the pleura: a clinical, histological and comparative genomic hybridization analysis of 14 cases. Virchows Arch (2005) 0.99
COX-2 is widely expressed in metaplastic epithelium in pulmonary fibrous disorders. Am J Clin Pathol (2006) 0.98
Effects of beta-carotene supplementation on molecular markers of lung carcinogenesis in male smokers. Cancer Prev Res (Phila) (2010) 0.98
Identification of specific gene copy number changes in asbestos-related lung cancer. Cancer Res (2006) 0.97
Genetic association studies in lumbar disc degeneration: a systematic review. PLoS One (2012) 0.97
Evidence of gene gene interactions in lung carcinogenesis in a large pooled analysis. Carcinogenesis (2007) 0.96
Similar DNA methylation pattern in lung tumours from smokers and never-smokers with second-hand tobacco smoke exposure. Mutagenesis (2012) 0.95
Heterogeneity of DNA methylation in multifocal prostate cancer. Virchows Arch (2014) 0.95
K-ras mutations in sinonasal cancers in relation to wood dust exposure. BMC Cancer (2008) 0.95
CYP2S1: a short review. Toxicol Appl Pharmacol (2005) 0.95
Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study. Mutat Res (2005) 0.94
Promoter hypermethylation in tumour suppressor genes shows association with stage, grade and invasiveness of bladder cancer. Oncology (2008) 0.93
Concurrent LOH at multiple loci in human malignant mesothelioma with preferential loss of NF2 gene region. Oncol Rep (2002) 0.92
Regulation of CYP3A5 by glucocorticoids and cigarette smoke in human lung-derived cells. J Pharmacol Exp Ther (2003) 0.92
Caveolins as tumour markers in lung cancer detected by combined use of cDNA and tissue microarrays. J Pathol (2004) 0.92
Influence of common XPD and XRCC1 variant alleles on p53 mutations in lung tumors. Environ Mol Mutagen (2003) 0.91
Localization of cytochrome P450 CYP2S1 expression in human tissues by in situ hybridization and immunohistochemistry. J Histochem Cytochem (2005) 0.88
Mutations in TP53 tumor suppressor gene in wood dust-related sinonasal cancer. Int J Cancer (2010) 0.88
Development and validation of a job exposure matrix for physical risk factors in low back pain. PLoS One (2012) 0.88
Frequent loss of heterozygosity at 6q in pheochromocytoma. Hum Pathol (2006) 0.88
Profile of TP53 gene mutations in sinonasal cancer. Mutat Res (2009) 0.87
Comparison of hardwood and softwood dust-induced expression of cytokines and chemokines in mouse macrophage RAW 264.7 cells. Toxicology (2005) 0.87
Copy number gains on 5p15, 6p11-q11, 7p12, and 8q24 are rare in sputum cells of individuals at high risk of lung cancer. Lung Cancer (2006) 0.85
Mechanisms of particle-induced pulmonary inflammation in a mouse model: exposure to wood dust. Toxicol Sci (2006) 0.85
Promoter hypermethylation in tumour suppressor genes and response to interleukin-2 treatment in bladder cancer: a pilot study. J Cancer Res Clin Oncol (2009) 0.85
Loss of heterozygosity at 6q is frequent and concurrent with 3p loss in sporadic and familial capillary hemangioblastomas. J Neuropathol Exp Neurol (2004) 0.84
Reduced Fhit protein expression and loss of heterozygosity at FHIT gene in tumours from smoking and asbestos-exposed lung cancer patients. Int J Oncol (2002) 0.84
Combined analysis of TMPRSS2-ERG and TERT for improved prognosis of biochemical recurrence in prostate cancer. Genes Chromosomes Cancer (2012) 0.83
EPHX1 gene polymorphisms and individual susceptibility to lung cancer. Cancer Lett (2005) 0.83
Chromosome 22q alterations and expression of the NF2 gene product, merlin, in gastrointestinal stromal tumors. Hum Pathol (2003) 0.83
Tumor suppressor gene ZAC/PLAGL1: altered expression and loss of the nonimprinted allele in pheochromocytomas. Cancer Genet (2011) 0.83
Molecular and genetic changes in asbestos-related lung cancer. Cancer Lett (2008) 0.81
Molecular alterations at 9q33.1 and polyploidy in asbestos-related lung cancer. Clin Cancer Res (2009) 0.81
Wood dusts induce the production of reactive oxygen species and caspase-3 activity in human bronchial epithelial cells. Toxicology (2009) 0.81
ROS-mediated TNF-alpha and MIP-2 gene expression in alveolar macrophages exposed to pine dust. Part Fibre Toxicol (2004) 0.81
Incidence of nonspecific and radiating low back pain: followup of 24-39-year-old adults of the Young Finns Study. Arthritis Care Res (Hoboken) (2010) 0.80
Glutathione S-transferases and aromatic DNA adducts in smokers' bronchoalveolar macrophages. Lung Cancer (2003) 0.80
Analysis of TP53 gene mutations in human lung cancer: comparison of capillary electrophoresis single strand conformation polymorphism assay with denaturing gradient gel electrophoresis and direct sequencing. Cancer Detect Prev (2006) 0.79
Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients. BMC Med Genomics (2008) 0.79
Immunomodulatory effects of oak dust exposure in a murine model of allergic asthma. Toxicol Sci (2007) 0.79
Reduced Fhit protein expression in human malignant mesothelioma. Virchows Arch (2003) 0.79
COX-2 and p53 in human sinonasal cancer: COX-2 expression is associated with adenocarcinoma histology and wood-dust exposure. Int J Cancer (2008) 0.78
Accumulation of genomic alterations in 2p16, 9q33.1 and 19p13 in lung tumours of asbestos-exposed patients. Mol Oncol (2012) 0.78
Evaluation of the biological activity of naturally occurring 5,8-dihydroxycoumarin. Molecules (2013) 0.77
Preferential loss of the nonimprinted allele for the ZAC1 tumor suppressor gene in human capillary hemangioblastoma. J Neuropathol Exp Neurol (2007) 0.77
Characterization of oak and birch dust-induced expression of cytokines and chemokines in mouse macrophage RAW 264.7 cells. Toxicology (2005) 0.77
Identification of genetic polymorphisms of CYP2S1 in a Finnish Caucasian population. Mutat Res (2004) 0.76
Relationship between TP53 tumour suppressor gene mutations and smoking-related bulky DNA adducts in a lung cancer study population from Hungary. Mutagenesis (2009) 0.76
Frequent methylation of RASSF1 and RARB in urine sediments from patients with early stage prostate cancer. Medicina (Kaunas) (2011) 0.76
Special Issue: The Proceedings of the 10th International Congress of Toxicology, Tampere, Finland, July 11-15, 2004. Living in a safe chemical world. Toxicol Appl Pharmacol (2005) 0.75
Driver Gene and Novel Mutations in Asbestos-Exposed Lung Adenocarcinoma and Malignant Mesothelioma Detected by Exome Sequencing. Lung (2016) 0.75
Spontaneous and benzo[a]pyrene-induced micronuclei in the embryos of the black-headed gull (Larus ridibundus L.). Mutat Res (2003) 0.75
Molecular epidemiology: convergence between toxicology and epidemiology. Mutat Res (2005) 0.75
Asthma incidence in wood-processing industries in Finland in a register-based population study. Scand J Work Environ Health (2008) 0.75
Legislative change enabling use of early part-time sick leave enhanced return to work and work participation in Finland. Scand J Work Environ Health (2017) 0.75