Published in Am J Geriatr Psychiatry on October 10, 2007
Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons. Arch Gen Psychiatry (2010) 2.07
Prevalence of depression among older Americans: the Aging, Demographics and Memory Study. Int Psychogeriatr (2009) 1.60
Symptoms of depression in survivors of severe sepsis: a prospective cohort study of older Americans. Am J Geriatr Psychiatry (2013) 1.09
Behavioural and psychological symptoms in the older population without dementia--relationship with socio-demographics, health and cognition. BMC Geriatr (2010) 0.91
Daily functioning and prefrontal brain morphology in healthy and depressed community-dwelling elderly. Am J Geriatr Psychiatry (2008) 0.88
Grouping of behavioural and psychological symptoms of dementia. Int J Geriatr Psychiatry (2013) 0.80
Form and Function of Sleep Spindles across the Lifespan. Neural Plast (2016) 0.75
Trajectories of Neuropsychiatric Symptoms and Cognitive Decline in Mild Cognitive Impairment. Am J Geriatr Psychiatry (2015) 0.75
The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 21.80
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron (2011) 20.15
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria. Lancet Neurol (2007) 18.62
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain (2011) 9.90
A global clinical measure of fitness and frailty in elderly people. CMAJ (2005) 8.99
Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol (2010) 8.74
Frailty in elderly people. Lancet (2013) 7.40
National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standards. Stroke (2006) 6.94
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol (2013) 6.18
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol (2007) 5.09
Frailty: an emerging research and clinical paradigm--issues and controversies. J Gerontol A Biol Sci Med Sci (2007) 4.98
Relative fitness and frailty of elderly men and women in developed countries and their relationship with mortality. J Am Geriatr Soc (2005) 4.48
The fugl-meyer assessment of motor recovery after stroke: a critical review of its measurement properties. Neurorehabil Neural Repair (2002) 4.47
A standard procedure for creating a frailty index. BMC Geriatr (2008) 4.40
Vascular cognitive impairment. Lancet Neurol (2003) 3.73
Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family. J Neurol Neurosurg Psychiatry (2010) 3.66
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron (2010) 3.44
Criteria for the diagnosis of corticobasal degeneration. Neurology (2013) 3.07
Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimers Dement (2011) 3.05
Incidence of and risk factors for nodding off at scientific sessions. CMAJ (2004) 2.97
Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke (2002) 2.87
Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. J Gerontol A Biol Sci Med Sci (2012) 2.82
Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. Lancet Neurol (2007) 2.72
Prevalence, attributes, and outcomes of fitness and frailty in community-dwelling older adults: report from the Canadian study of health and aging. J Gerontol A Biol Sci Med Sci (2004) 2.67
The cognitive profile of posterior cortical atrophy. Neurology (2006) 2.64
Frailty, fitness and late-life mortality in relation to chronological and biological age. BMC Geriatr (2002) 2.63
Evidence from functional neuroimaging of a compensatory prefrontal network in Alzheimer's disease. J Neurosci (2003) 2.63
Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial. Lancet Neurol (2008) 2.62
The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene. Brain (2006) 2.52
Nonpharmacological therapies in Alzheimer's disease: a systematic review of efficacy. Dement Geriatr Cogn Disord (2010) 2.49
Operationalizing a frailty index from a standardized comprehensive geriatric assessment. J Am Geriatr Soc (2004) 2.47
Diagnostic criteria for the behavioral variant of frontotemporal dementia (bvFTD): current limitations and future directions. Alzheimer Dis Assoc Disord (2007) 2.43
A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. JAMA Neurol (2013) 2.32
Frailty and the geriatrician. Age Ageing (2004) 2.32
Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance. Neurobiol Aging (2010) 2.27
The estimation of relative fitness and frailty in community-dwelling older adults using self-report data. J Gerontol A Biol Sci Med Sci (2004) 2.19
Measurement, correlates, and health outcomes of medication adherence among seniors. Ann Pharmacother (2003) 2.19
Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people. Arch Neurol (2002) 2.18
Development of a frailty index for patients with coronary artery disease. J Am Geriatr Soc (2010) 2.18
Gait asymmetry in community-ambulating stroke survivors. Arch Phys Med Rehabil (2008) 2.10
Validity and reliability of the Edmonton Frail Scale. Age Ageing (2006) 2.08
Prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geriatr Soc (2010) 2.06
Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Arch Neurol (2008) 2.03
Evaluation of gait symmetry after stroke: a comparison of current methods and recommendations for standardization. Gait Posture (2009) 1.99
Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging. Dement Geriatr Cogn Disord (2002) 1.95
TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia. Acta Neuropathol (2014) 1.90
Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease. Stroke (2008) 1.89
Ubiquitin immunohistochemistry suggests classic motor neuron disease, motor neuron disease with dementia, and frontotemporal dementia of the motor neuron disease type represent a clinicopathologic spectrum. J Neuropathol Exp Neurol (2005) 1.87
Family physicians' attitudes and practices regarding assessments of medical fitness to drive in older persons. J Gen Intern Med (2007) 1.86
TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease. Mol Neurodegener (2013) 1.83
Variations in case definition affect prevalence but not outcomes of mild cognitive impairment. Neurology (2003) 1.82
Clinical and pathological features of familial frontotemporal dementia caused by C9ORF72 mutation on chromosome 9p. Brain (2012) 1.81
Nontraditional risk factors combine to predict Alzheimer disease and dementia. Neurology (2011) 1.81
Functional status in rate- versus rhythm-control strategies for atrial fibrillation: results of the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Functional Status Substudy. J Am Coll Cardiol (2005) 1.77
Imaging markers for Alzheimer disease: which vs how. Neurology (2013) 1.76
A new visual rating scale to assess strategic white matter hyperintensities within cholinergic pathways in dementia. Stroke (2005) 1.74
Cholesterol in Alzheimer's disease. Lancet Neurol (2005) 1.72
C9ORF72 repeat expansions in cases with previously identified pathogenic mutations. Neurology (2013) 1.70
The case of K.C.: contributions of a memory-impaired person to memory theory. Neuropsychologia (2005) 1.68
Frailty, body mass index, and abdominal obesity in older people. J Gerontol A Biol Sci Med Sci (2009) 1.67
Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease. Neuroimage (2008) 1.62
Ataxin-2 repeat-length variation and neurodegeneration. Hum Mol Genet (2011) 1.60
Frailty in relation to variations in hormone levels of the hypothalamic-pituitary-testicular axis in older men: results from the European male aging study. J Am Geriatr Soc (2011) 1.57
The mortality rate as a function of accumulated deficits in a frailty index. Mech Ageing Dev (2002) 1.56
Frailty and its definition: a worthy challenge. J Am Geriatr Soc (2005) 1.55
An international needs assessment of caregivers for frontotemporal dementia. Can J Neurol Sci (2011) 1.55
Diagnosis and treatment of dementia: 2. Diagnosis. CMAJ (2008) 1.55
Utility-based Quality of Life measures in Alzheimer's disease. Qual Life Res (2006) 1.55
Predicting post-operative delirium in elective orthopaedic patients: the Delirium Elderly At-Risk (DEAR) instrument. Age Ageing (2005) 1.52
Anterior brain glucose hypometabolism predates dementia in progranulin mutation carriers. Neurology (2013) 1.50
Rates of influenza vaccination in older adults and factors associated with vaccine use: a secondary analysis of the Canadian Study of Health and Aging. BMC Public Health (2004) 1.49
Vascular cognitive impairment: current concepts and clinical developments. Lancet Neurol (2008) 1.48
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet (2012) 1.46
Cueing the personal future to reduce discounting in intertemporal choice: Is episodic prospection necessary? Hippocampus (2015) 1.46
A novel PS1 gene mutation in a large Aboriginal kindred. Can J Neurol Sci (2010) 1.46
Canadian Cardiovascular Society Consensus Conference 2002: Management of heart disease in the elderly patient. Can J Cardiol (2004) 1.44
Social vulnerability, frailty and mortality in elderly people. PLoS One (2008) 1.42
Going from bad to worse: a stochastic model of transitions in deficit accumulation, in relation to mortality. Mech Ageing Dev (2006) 1.41
A procedure for creating a frailty index based on deficit accumulation in aging mice. J Gerontol A Biol Sci Med Sci (2011) 1.41
Inter-rater reliability of delirium rating scales. Neuroepidemiology (2005) 1.40
Coma with accidental single dose of an atypical neuroleptic in a patient with Lewy Body dementia. Am J Geriatr Psychiatry (2003) 1.39
The core and halo of primary progressive aphasia and semantic dementia. Ann Neurol (2003) 1.39
Recommendations of the 4th Canadian Consensus Conference on the Diagnosis and Treatment of Dementia (CCCDTD4). Can Geriatr J (2012) 1.39
Can we prevent Alzheimer's disease? Secondary "prevention" trials in Alzheimer's disease. Alzheimers Dement (2013) 1.38
Operationalization of frailty using eight commonly used scales and comparison of their ability to predict all-cause mortality. J Am Geriatr Soc (2013) 1.35