Published in Ann N Y Acad Sci on October 12, 2007
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet (2012) 1.77
Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene. Protein Cell (2010) 1.07
Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase. BMC Cancer (2010) 0.96
Gene therapy of Cav1.2 channel with VIP and VIP receptor agonists and antagonists: a novel approach to designing promotility and antimotility agents. Am J Physiol Gastrointest Liver Physiol (2008) 0.91
The Splicing Factor SRSF1 as a Marker for Endothelial Senescence. Front Physiol (2012) 0.88
The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells. PLoS One (2013) 0.84
Tumor suppressors p53, p63TAα, p63TAy, p73α, and p73β use distinct pathways to repress telomerase expression. J Biol Chem (2012) 0.80
Evidence for activation of the TGF-beta1 promoter by C/EBPbeta and its modulation by Smads. J Interferon Cytokine Res (2009) 0.80
TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence. Protein Cell (2016) 0.75
Polymorphism of human cytochrome P450 enzymes and its clinical impact. Drug Metab Rev (2009) 2.16
Establishment, immortalisation and characterisation of pteropid bat cell lines. PLoS One (2009) 1.45
Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc. J Biol Chem (2008) 1.34
TERT regulates cell survival independent of telomerase enzymatic activity. Oncogene (2002) 1.31
ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton. Cancer Res (2013) 1.25
Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family. Ann N Y Acad Sci (2007) 1.21
Hormones and growth factors regulate telomerase activity in ageing and cancer. Mol Cell Endocrinol (2005) 1.16
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging. J Infect Dis (2013) 1.16
Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. Drug Metab Rev (2010) 1.15
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene. J Biol Chem (2006) 1.12
GAPDH: a common enzyme with uncommon functions. Clin Exp Pharmacol Physiol (2012) 1.10
Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension. FASEB J (2002) 1.00
Herbal interactions with anticancer drugs: mechanistic and clinical considerations. Curr Med Chem (2010) 0.93
Potential roles for estrogen regulation of telomerase activity in aging. Ann N Y Acad Sci (2007) 0.92
Telomere protein complexes and interactions with telomerase in telomere maintenance. Front Biosci (Landmark Ed) (2011) 0.92
Dehydroepiandrosterone inhibits human vascular smooth muscle cell proliferation independent of ARs and ERs. J Clin Endocrinol Metab (2002) 0.91
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study. Xenobiotica (2010) 0.90
Estrogen deficiency reversibly induces telomere shortening in mouse granulosa cells and ovarian aging in vivo. Protein Cell (2011) 0.90
Molecular regulation of telomerase activity in aging. Protein Cell (2011) 0.90
Bone morphogenetic protein-7 inhibits telomerase activity, telomere maintenance, and cervical tumor growth. Cancer Res (2008) 0.89
Niemann-Pick Disease Type C: from molecule to clinic. Clin Exp Pharmacol Physiol (2009) 0.88
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component. Proc Natl Acad Sci U S A (2012) 0.87
Estrogen deficiency leads to telomerase inhibition, telomere shortening and reduced cell proliferation in the adrenal gland of mice. Cell Res (2008) 0.87
Phenotype prediction of deleterious nonsynonymous single nucleotide polymorphisms in human alcohol metabolism-related genes: a bioinformatics study. Alcohol (2010) 0.86
TGF-beta induces telomerase-dependent pancreatic tumor cell cycle arrest. Mol Cell Endocrinol (2010) 0.85
Human CYP2C8: structure, substrate specificity, inhibitor selectivity, inducers and polymorphisms. Curr Drug Metab (2009) 0.85
Substrate specificity, inhibitors and regulation of human cytochrome P450 2D6 and implications in drug development. Curr Med Chem (2009) 0.84
Alternative lengthening of telomeres in hTERT-inhibited laryngeal cancer cells. Cancer Sci (2010) 0.83
Oestrogen, telomerase, ovarian ageing and cancer. Clin Exp Pharmacol Physiol (2009) 0.83
TGF-beta and cancer: is Smad3 a repressor of hTERT gene? Cell Res (2006) 0.83
Prediction of deleterious non-synonymous single-nucleotide polymorphisms of human uridine diphosphate glucuronosyltransferase genes. AAPS J (2009) 0.83
Suppression of the notch signaling pathway by γ-secretase inhibitor GSI inhibits human nasopharyngeal carcinoma cell proliferation. Cancer Lett (2011) 0.83
Effects of 17beta-estradiol on growth and apoptosis in human vascular endothelial cells: influence of mechanical strain and tumor necrosis factor-alpha. Steroids (2006) 0.82
Osteopontin promotes inflammation in patients with acute coronary syndrome through its activity on IL-17 producing cells. Eur J Immunol (2012) 0.82
Ets2 transcription factor, telomerase activity and breast cancer. Clin Exp Pharmacol Physiol (2009) 0.81
Retracted Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3. FASEB J (2009) 0.81
Cellular senescence occurred widespread to multiple selective sites in the fetal tissues and organs of mice. Clin Exp Pharmacol Physiol (2014) 0.81
Uses of telomerase peptides in anti-tumor immune therapy. Methods Mol Biol (2007) 0.80
High glucose abolishes the antiproliferative effect of 17beta-estradiol in human vascular smooth muscle cells. Am J Physiol Endocrinol Metab (2002) 0.80
Chromosomal and telomeric reprogramming following ES-somatic cell fusion. Chromosoma (2009) 0.80
Application of combination of short hairpin RNA segments for silencing VEGF, TERT and Bcl-xl expression in laryngeal squamous carcinoma. Cancer Biol Ther (2008) 0.80
A turning point: focusing on translational medicine. Clin Exp Pharmacol Physiol (2013) 0.79
Signaling on telomerase: a master switch in cell aging and immortalization. Biogerontology (2002) 0.79
The C-terminus of PRK2/PKNgamma is required for optimal activation by RhoA in a GTP-dependent manner. Arch Biochem Biophys (2008) 0.79
Inhibition of telomerase by targeting MAP kinase signaling. Methods Mol Biol (2007) 0.78
Diagnostic Value of Common Inflammatory Markers on Fever of Unknown Origin. Jpn J Infect Dis (2016) 0.78
Telomerase down-regulation does not mediate PC12 pheochromocytoma cell differentiation induced by NGF, but requires MAP kinase signalling. J Neurochem (2005) 0.77
Current aging research in China. Protein Cell (2015) 0.77
Modulators of multidrug resistance associated proteins in the management of anticancer and antimicrobial drug resistance and the treatment of inflammatory diseases. Curr Top Med Chem (2010) 0.77
αB-Crystallin R120G variant causes cardiac arrhythmias and alterations in the expression of Ca(2+) -handling proteins and endoplasmic reticulum stress in mice. Clin Exp Pharmacol Physiol (2014) 0.77
Serine/threonine-protein phosphatase 2A physically interacts with human telomerase reverse transcriptase hTERT and regulates its subcellular distribution. J Cell Biochem (2013) 0.76
Contribution of ultrasound-guided fine-needle aspiration cell blocks of metastatic supraclavicular lymph nodes to the diagnosis of lung cancer. J Cancer Res Ther (2015) 0.76
Comparison of reprogramming ability of mouse ES and iPS cells measured by somatic cell fusion. Int J Dev Biol (2010) 0.76
Molecular dynamics and principal components of potassium binding with human telomeric intra-molecular G-quadruplex. Protein Cell (2015) 0.75
Stability and conformational change of methoxypolyethylene glycol modification for native and unfolded trypsin. Food Chem (2013) 0.75
Introduction: Understanding the signalling mechanisms in molecular physiology and diseases. Clin Exp Pharmacol Physiol (2012) 0.75
[Concentration retrieving method of SO2 using differential optical absorption spectroscopy based on statistics]. Guang Pu Xue Yu Guang Pu Fen Xi (2011) 0.75
Experimental study of leflunomide on renal protective effect and on inflammatory response of streptozotocin induced diabetic rats. Nephrology (Carlton) (2012) 0.75
Increased polymerase I and transcript release factor (Cavin-1) expression attenuates platelet-derived growth factor receptor signalling in senescent human fibroblasts. Clin Exp Pharmacol Physiol (2014) 0.75
Activin inhibits telomerase activity in cancer. Biochem Biophys Res Commun (2009) 0.75