PubRank

Tony Wyss-Coray

Author PubWeight™ 93.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med 2007 6.80
2 The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 2011 6.71
3 The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J Clin Invest 2008 4.09
4 Immune activation in brain aging and neurodegeneration: too much or too little? Neuron 2009 3.76
5 Identification of a central role for complement in osteoarthritis. Nat Med 2011 3.11
6 Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in alpha-synuclein models of Parkinson's and Lewy body diseases. J Neurosci 2009 2.82
7 Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice. Proc Natl Acad Sci U S A 2003 2.24
8 Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice. J Neurosci 2004 2.07
9 Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain. Neuron 2003 2.02
10 Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology. J Clin Invest 2006 1.87
11 Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis. J Clin Invest 2007 1.78
12 TDP-43 frontotemporal lobar degeneration and autoimmune disease. J Neurol Neurosurg Psychiatry 2013 1.74
13 All-you-can-eat: autophagy in neurodegeneration and neuroprotection. Mol Neurodegener 2009 1.60
14 Genes contributing to prion pathogenesis. J Gen Virol 2008 1.51
15 Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration. Proc Natl Acad Sci U S A 2006 1.47
16 Highly sensitive and specific bioassay for measuring bioactive TGF-beta. BMC Cell Biol 2006 1.42
17 The immunology of neurodegeneration. J Clin Invest 2012 1.41
18 Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury. J Immunol 2005 1.39
19 Angiotensin II sustains brain inflammation in mice via TGF-beta. J Clin Invest 2010 1.39
20 Chronically increased transforming growth factor-beta1 strongly inhibits hippocampal neurogenesis in aged mice. Am J Pathol 2006 1.38
21 Neural progenitor cells regulate microglia functions and activity. Nat Neurosci 2012 1.34
22 Selective expansion of foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells. J Immunol 2007 1.32
23 The p75 neurotrophin receptor promotes amyloid-beta(1-42)-induced neuritic dystrophy in vitro and in vivo. J Neurosci 2009 1.31
24 Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival. J Exp Med 2013 1.27
25 Microglial beclin 1 regulates retromer trafficking and phagocytosis and is impaired in Alzheimer's disease. Neuron 2013 1.26
26 Complement receptor 2 is expressed in neural progenitor cells and regulates adult hippocampal neurogenesis. J Neurosci 2011 1.23
27 The role of inflammation in age-related disease. Aging (Albany NY) 2013 1.22
28 Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One 2010 1.22
29 Collagen VI protects neurons against Abeta toxicity. Nat Neurosci 2009 1.19
30 Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function. Brain Behav 2012 1.15
31 Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease. J Neuroinflammation 2008 1.13
32 Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease. J Biol Chem 2003 1.08
33 Insights into the pathogenesis of hydrocephalus from transgenic and experimental animal models. Brain Pathol 2004 1.08
34 Killing pain, killing neurons? Nat Med 2005 0.99
35 Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice. Am J Pathol 2010 0.98
36 A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models. Curr Alzheimer Res 2006 0.98
37 Immune cells may fend off Alzheimer disease. Nat Med 2007 0.97
38 Orally administered TGF-beta is biologically active in the intestinal mucosa and enhances oral tolerance. J Allergy Clin Immunol 2007 0.96
39 Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. J Neuroimmunol 2006 0.96
40 Autophagy in dementias. Brain Pathol 2012 0.95
41 Systemic and acquired immune responses in Alzheimer's disease. Int Rev Neurobiol 2007 0.95
42 Beclin 1 complex in autophagy and Alzheimer disease. Arch Neurol 2010 0.95
43 Blood protein signature for the early diagnosis of Alzheimer disease. Arch Neurol 2008 0.95
44 Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. Neurobiol Aging 2013 0.92
45 Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation. J Exp Med 2014 0.92
46 Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome. Mol Cell Proteomics 2011 0.92
47 Heparan sulfate subdomains that are degraded by Sulf accumulate in cerebral amyloid ß plaques of Alzheimer's disease: evidence from mouse models and patients. Am J Pathol 2012 0.92
48 Modelling neuroinflammatory phenotypes in vivo. J Neuroinflammation 2004 0.91
49 The circulatory systemic environment as a modulator of neurogenesis and brain aging. Autoimmun Rev 2012 0.90
50 Increased T cell recruitment to the CNS after amyloid beta 1-42 immunization in Alzheimer's mice overproducing transforming growth factor-beta 1. J Neurosci 2006 0.89
51 Deficiency of terminal complement pathway inhibitor promotes neuronal tau pathology and degeneration in mice. J Neuroinflammation 2012 0.88
52 Microglia--a wrench in the running wheel? Neuron 2008 0.87
53 APOE ε4 worsens hippocampal CA1 apical neuropil atrophy and episodic memory. Neurology 2014 0.86
54 Reduced brain tissue perfusion in TGF-beta 1 transgenic mice showing Alzheimer's disease-like cerebrovascular abnormalities. Neurobiol Dis 2005 0.86
55 Live imaging of Smad2/3 signaling in mouse skin wound healing. Wound Repair Regen 2007 0.83
56 Chronic over-expression of TGFβ1 alters hippocampal structure and causes learning deficits. Hippocampus 2013 0.81
57 Changes of the enteric nervous system in amyloid-β protein precursor transgenic mice correlate with disease progression. J Alzheimers Dis 2013 0.80
58 Immunotherapy of cerebrovascular amyloidosis in a transgenic mouse model. Neurobiol Aging 2011 0.80
59 Small molecule tgf-beta mimetics as potential neuroprotective factors. Curr Alzheimer Res 2005 0.78
60 Bioluminescence analysis of Smad-dependent TGF-beta signaling in live mice. Methods Mol Biol 2009 0.78
61 A revival of parabiosis in biomedical research. Swiss Med Wkly 2014 0.78
62 Molecular and functional dissection of TGF-beta1-induced cerebrovascular abnormalities in transgenic mice. Ann N Y Acad Sci 2002 0.78
63 Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3. J Neurochem 2009 0.77
64 In vitro analysis of transforming growth factor-beta1 inhibition in novel transgenic SBE-luciferase mice. Ann Plast Surg 2007 0.77
65 Sorting through the roles of beclin 1 in microglia and neurodegeneration. J Neuroimmune Pharmacol 2014 0.77
66 Targeting autophagy for disease therapy. Nat Biotechnol 2013 0.76
67 The 1st International standard for transforming growth factor-β3 (TGF-β3). J Immunol Methods 2012 0.75
68 Workshop summary: roles of the TNF family in neuronal development, function and pathology. Adv Exp Med Biol 2011 0.75