Published in J Neurosurg on October 01, 2007
Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here? Br J Pharmacol (2011) 1.28
Amyloid-beta protofibril levels correlate with spatial learning in Arctic Alzheimer's disease transgenic mice. FEBS J (2009) 1.08
Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice. J Neurotrauma (2010) 1.00
Cognitive recovery in the aged rat after stroke and anti-Nogo-A immunotherapy. Behav Brain Res (2009) 0.92
Functional outcome is impaired following traumatic brain injury in aging Nogo-A/B-deficient mice. Neuroscience (2009) 0.89
Hippocampal expression of myelin-associated inhibitors is induced with age-related cognitive decline and correlates with deficits of spatial learning and memory. J Neurochem (2012) 0.88
Traumatic axonal injury in the mouse is accompanied by a dynamic inflammatory response, astroglial reactivity and complex behavioral changes. J Neuroinflammation (2013) 0.87
Nogo-A-deficient Transgenic Rats Show Deficits in Higher Cognitive Functions, Decreased Anxiety, and Altered Circadian Activity Patterns. Front Behav Neurosci (2014) 0.86
Muscle structure influences utrophin expression in mdx mice. PLoS Genet (2014) 0.81
Chronic Histopathological and Behavioral Outcomes of Experimental Traumatic Brain Injury in Adult Male Animals. J Neurotrauma (2015) 0.81
Inhibition of Nogo-66 receptor 1 enhances recovery of cognitive function after traumatic brain injury in mice. J Neurotrauma (2013) 0.79
Indomethacin protects rats from neuronal damage induced by traumatic brain injury and suppresses hippocampal IL-1β release through the inhibition of Nogo-A expression. J Neuroinflammation (2012) 0.78
Anti-Nogo-A Immunotherapy Does Not Alter Hippocampal Neurogenesis after Stroke in Adult Rats. Front Neurosci (2016) 0.75
Nogo presence is inversely associated with shifts in cortical microglial morphology following experimental diffuse brain injury. Neuroscience (2017) 0.75
Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods (1984) 16.43
Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature (2001) 4.96
Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat Rev Neurosci (2003) 4.60
GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci (1997) 3.50
Diffuse axonal injury in head injury: definition, diagnosis and grading. Histopathology (1989) 3.24
Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates. Nat Med (2006) 3.23
Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature (1990) 3.22
Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions. Nat Neurosci (1998) 3.15
Update of neuropathology and neurological recovery after traumatic brain injury. J Head Trauma Rehabil (2005) 3.12
Traumatic brain injury in the rat: characterization of a lateral fluid-percussion model. Neuroscience (1989) 2.91
Rho signaling pathway targeted to promote spinal cord repair. J Neurosci (2002) 2.90
Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury. Neuron (2004) 2.76
Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell (1995) 2.75
A new role for Nogo as a regulator of vascular remodeling. Nat Med (2004) 2.63
Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons. Nat Neurosci (2001) 2.53
TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration. Neuron (2005) 2.39
A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein. Nat Neurosci (2002) 2.30
Staining of amyloid precursor protein to study axonal damage in mild head injury. Lancet (1994) 2.27
Nogo-A antibody improves regeneration and locomotion of spinal cord-injured rats. Ann Neurol (2005) 2.22
Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions. J Neurosci (2003) 2.03
A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats. Neuroscience (2006) 1.95
A mechanistic analysis of nondisruptive axonal injury: a review. J Neurotrauma (1997) 1.75
Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats. Neuroscience (1998) 1.60
Counteracting the Nogo receptor enhances optic nerve regeneration if retinal ganglion cells are in an active growth state. J Neurosci (2004) 1.51
Delayed treatment with monoclonal antibody IN-1 1 week after stroke results in recovery of function and corticorubral plasticity in adult rats. J Cereb Blood Flow Metab (2005) 1.48
Evaluation of memory dysfunction following experimental brain injury using the Morris water maze. J Neurotrauma (1991) 1.46
Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat. Ann Neurol (2002) 1.44
Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats. J Cereb Blood Flow Metab (2003) 1.42
Inhibition of Nogo: a key strategy to increase regeneration, plasticity and functional recovery of the lesioned central nervous system. Ann Med (2005) 1.42
Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord. J Neurosci (2002) 1.31
Synaptogenesis in the hippocampal CA1 field following traumatic brain injury. J Neurotrauma (2005) 1.29
Enhanced learning after genetic overexpression of a brain growth protein. Proc Natl Acad Sci U S A (2000) 1.27
Targeting the Nogo receptor to treat central nervous system injuries. Nat Rev Drug Discov (2003) 1.25
Relationship of calpain-mediated proteolysis to the expression of axonal and synaptic plasticity markers following traumatic brain injury in mice. Exp Neurol (2006) 1.24
Molecular approaches to spinal cord repair. Annu Rev Neurosci (2003) 1.20
Regenerating corticospinal fibers in the Marmoset (Callitrix jacchus) after spinal cord lesion and treatment with the anti-Nogo-A antibody IN-1. Eur J Neurosci (2004) 1.19
Insulin-like growth factor-1 (IGF-1) improves both neurological motor and cognitive outcome following experimental brain injury. Exp Neurol (1997) 1.17
Tissue tears in the white matter after lateral fluid percussion brain injury in the rat: relevance to human brain injury. Acta Neuropathol (2000) 1.08
Plasticity following injury to the adult central nervous system: is recapitulation of a developmental state worth promoting? J Neurotrauma (2003) 1.06
Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat. Exp Neurol (1991) 1.04
Delayed inhibition of Nogo-A does not alter injury-induced axonal sprouting but enhances recovery of cognitive function following experimental traumatic brain injury in rats. Neuroscience (2005) 1.04
Intrathecally infused antibodies against Nogo-A penetrate the CNS and downregulate the endogenous neurite growth inhibitor Nogo-A. Mol Cell Neurosci (2006) 1.03
Differential effects of the anticonvulsant topiramate on neurobehavioral and histological outcomes following traumatic brain injury in rats. J Neurotrauma (2004) 0.99
Regulation of Nogo and Nogo receptor during the development of the entorhino-hippocampal pathway and after adult hippocampal lesions. Mol Cell Neurosci (2004) 0.99
Hippocampal-dependent memory is impaired in heterozygous GAP-43 knockout mice. Hippocampus (2005) 0.98
Nogo and the Nogo-66 receptor. Prog Brain Res (2002) 0.97
Riluzole attenuates cortical lesion size, but not hippocampal neuronal loss, following traumatic brain injury in the rat. J Neurosci Res (1998) 0.96
Myelin-associated inhibitors of axon regeneration. J Neurosci Res (2003) 0.96
Corticostriatal plasticity is restricted by myelin-associated neurite growth inhibitors in the adult rat. Ann Neurol (1999) 0.96
Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat. Exp Neurol (2006) 0.95
Characterization of a prolonged regenerative attempt by diffusely injured axons following traumatic brain injury in adult cat: a light and electron microscopic immunocytochemical study. Acta Neuropathol (1997) 0.93
Functional reorganization of the motor cortex in adult rats after cortical lesion and treatment with monoclonal antibody IN-1. J Neurosci (2003) 0.93
Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma. J Comp Neurol (2000) 0.93
Traumatic brain injury in rats results in increased expression of Gap-43 that correlates with behavioral recovery. Neurosci Lett (1998) 0.91
An engineered IN-1 F(ab) fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing activity. Protein Eng (2002) 0.90
Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody. Eur J Neurosci (2006) 0.89
GAP-43 overexpression in adult mouse Purkinje cells overrides myelin-derived inhibition of neurite growth. Eur J Neurosci (2004) 0.89
A point mutant of GAP-43 induces enhanced short-term and long-term hippocampal plasticity. Eur J Neurosci (2002) 0.88
Molecular analysis of Nogo expression in the hippocampus during development and following lesion and seizure. FASEB J (2003) 0.86
Administration of monoclonal antibodies neutralizing the inflammatory mediators tumor necrosis factor alpha and interleukin -6 does not attenuate acute behavioral deficits following experimental traumatic brain injury in the rat. Restor Neurol Neurosci (2005) 0.82
Function of the hippocampus in memory formation: desperately seeking resolution. Prog Neuropsychopharmacol Biol Psychiatry (2001) 0.81
Transient expression of GAP-43 within the hippocampus after global brain ischemia in rat. Cell Tissue Res (1997) 0.80
Regeneration of Lesioned Septohippocampal Acetylcholinesterase-positive Axons is Improved by Antibodies Against the Myelin-associated Neurite Growth Inhibitors NI-35/250. Eur J Neurosci (1991) 0.79
Neutralizing antibodies against neurite growth inhibitor NI-35/250 do not promote regeneration of sensory axons in the adult rat spinal cord. Neuroscience (2000) 0.78
The injured spinal cord spontaneously forms a new intraspinal circuit in adult rats. Nat Neurosci (2004) 5.36
Clinical trials in head injury. J Neurotrauma (2002) 4.34
In vivo imaging of axonal degeneration and regeneration in the injured spinal cord. Nat Med (2005) 3.88
Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates. Nat Med (2006) 3.23
A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis. Nat Med (2011) 3.00
Reduced mortality rate in patients with severe traumatic brain injury treated with brain tissue oxygen monitoring. J Neurosurg (2005) 2.75
Hypoxia is important in the biology and aggression of human glial brain tumors. Clin Cancer Res (2004) 2.73
Imaging axonal transport of mitochondria in vivo. Nat Methods (2007) 2.60
Deep brain stimulation in the treatment of obesity. J Neurosurg (2008) 2.40
Lateral fluid percussion brain injury: a 15-year review and evaluation. J Neurotrauma (2005) 2.37
Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury. Neuron (2003) 2.32
Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord. J Neurosci (2005) 2.30
Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans? Nat Med (2007) 2.29
Patterns of Nogo mRNA and protein expression in the developing and adult rat and after CNS lesions. J Neurosci (2002) 2.27
Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults. Neurocrit Care (2010) 2.26
Improving outcome after stroke: overcoming the translational roadblock. Cerebrovasc Dis (2008) 2.26
Is aggressive treatment of traumatic brain injury cost-effective? J Neurosurg (2012) 2.22
Nogo-A antibody improves regeneration and locomotion of spinal cord-injured rats. Ann Neurol (2005) 2.22
Nogo-A inhibits neurite outgrowth and cell spreading with three discrete regions. J Neurosci (2003) 2.03
Nogo and its paRTNers. Trends Cell Biol (2003) 1.90
Nogo-A-deficient mice reveal strain-dependent differences in axonal regeneration. J Neurosci (2006) 1.89
Monocyte chemoattractant protein-1 deficiency is protective in a murine stroke model. J Cereb Blood Flow Metab (2002) 1.88
Motor and cognitive function evaluation following experimental traumatic brain injury. Neurosci Biobehav Rev (2004) 1.80
Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology. Arch Neurol (2011) 1.67
Constraint-induced movement therapy in the adult rat after unilateral corticospinal tract injury. J Neurosci (2008) 1.65
C1-inhibitor attenuates neurobehavioral deficits and reduces contusion volume after controlled cortical impact brain injury in mice. Crit Care Med (2009) 1.64
Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord. Eur J Neurosci (2011) 1.62
Nogo-A, -B, and -C are found on the cell surface and interact together in many different cell types. J Biol Chem (2005) 1.61
Rewiring of the corticospinal tract in the adult rat after unilateral stroke and anti-Nogo-A therapy. Brain (2013) 1.59
Constitutive EGFR signaling confers a motile phenotype to neural stem cells. Mol Cell Neurosci (2003) 1.58
Transplanted neural stem cells survive, differentiate, and improve neurological motor function after experimental traumatic brain injury. Neurosurgery (2002) 1.55
Reorganization of descending motor tracts in the rat spinal cord. Eur J Neurosci (2002) 1.55
Impact of the Accreditation Council for Graduate Medical Education work-hour regulations on neurosurgical resident education and productivity. J Neurosurg (2009) 1.53
Deep brain stimulation of the midbrain locomotor region improves paretic hindlimb function after spinal cord injury in rats. Sci Transl Med (2013) 1.53
Inflammation, degeneration and regeneration in the injured spinal cord: insights from DNA microarrays. Trends Neurosci (2003) 1.52
From cell death to neuronal regeneration: building a new brain after traumatic brain injury. J Neuropathol Exp Neurol (2003) 1.51
Sprouting, regeneration and circuit formation in the injured spinal cord: factors and activity. Philos Trans R Soc Lond B Biol Sci (2006) 1.48
Delayed treatment with monoclonal antibody IN-1 1 week after stroke results in recovery of function and corticorubral plasticity in adult rats. J Cereb Blood Flow Metab (2005) 1.48
Temporal window of vulnerability to repetitive experimental concussive brain injury. Neurosurgery (2005) 1.48
Functional recovery and neuroanatomical plasticity following middle cerebral artery occlusion and IN-1 antibody treatment in the adult rat. Ann Neurol (2002) 1.44
Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats. J Cereb Blood Flow Metab (2003) 1.42
Inhibition of Nogo: a key strategy to increase regeneration, plasticity and functional recovery of the lesioned central nervous system. Ann Med (2005) 1.42
Brain hyperthermia after traumatic brain injury does not reduce brain oxygen. Neurosurgery (2008) 1.42
A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family. FASEB J (2003) 1.42
Protein accumulation in traumatic brain injury. Neuromolecular Med (2003) 1.41
Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology. Ann Neurol (2010) 1.39
A panel of neuron-enriched proteins as markers for traumatic brain injury in humans. J Neurotrauma (2009) 1.39
Animal models of post-traumatic epilepsy. J Neurotrauma (2006) 1.38
Proteins released from degenerating neurons are surrogate markers for acute brain damage. Neurobiol Dis (2004) 1.38
Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cord. Mol Cell Neurosci (2006) 1.38
Long-lasting sprouting and gene expression changes induced by the monoclonal antibody IN-1 in the adult spinal cord. J Neurosci (2002) 1.31
Targeting experimental autoimmune encephalomyelitis lesions to a predetermined axonal tract system allows for refined behavioral testing in an animal model of multiple sclerosis. Am J Pathol (2004) 1.31
Mitochondrial damage and dysfunction in traumatic brain injury. Mitochondrion (2004) 1.30
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors. J Neurochem (2007) 1.30
Functional and anatomical reorganization of the sensory-motor cortex after incomplete spinal cord injury in adult rats. J Neurosci (2009) 1.28
Neutralization of interleukin-1beta modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice. Eur J Neurosci (2009) 1.27
Elevated intracranial pressures in spontaneous cerebrospinal fluid leaks. Am J Rhinol (2003) 1.26
Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury. Brain (2009) 1.25
Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus. J Cereb Blood Flow Metab (2003) 1.25
Remodeling of axonal connections contributes to recovery in an animal model of multiple sclerosis. J Exp Med (2004) 1.25
Thalamic nuclei after human blunt head injury. J Neuropathol Exp Neurol (2006) 1.24
Genomic structure and functional characterisation of the promoters of human and mouse nogo/rtn4. J Mol Biol (2003) 1.23
Spontaneous cerebrospinal fluid leaks: a variant of benign intracranial hypertension. Ann Otol Rhinol Laryngol (2006) 1.23
Using informatics to capture older adults' wellness. Int J Med Inform (2011) 1.23
Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease. J Neurosci (2002) 1.23
Recovery and brain reorganization after stroke in adult and aged rats. Ann Neurol (2005) 1.23
Nogo-A stabilizes the architecture of hippocampal neurons. J Neurosci (2010) 1.22
The role of Nogo-A in axonal plasticity, regrowth and repair. Cell Tissue Res (2012) 1.22
Dendritic plasticity in the adult rat following middle cerebral artery occlusion and Nogo-a neutralization. Cereb Cortex (2005) 1.22
Rewiring of hindlimb corticospinal neurons after spinal cord injury. Nat Neurosci (2009) 1.20
Targeting monocyte chemoattractant protein-1 signalling in disease. Expert Opin Ther Targets (2003) 1.19
Nogo-A and myelin-associated glycoprotein differently regulate oligodendrocyte maturation and myelin formation. J Neurosci (2008) 1.18
NogoA restricts synaptic plasticity in the adult hippocampus on a fast time scale. Proc Natl Acad Sci U S A (2011) 1.18
Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes. J Neuropathol Exp Neurol (2002) 1.18
Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons. Exp Neurol (2009) 1.18
Anti-Nogo on the go: from animal models to a clinical trial. Ann N Y Acad Sci (2010) 1.17
Anti-Nogo-A antibody treatment enhances sprouting of corticospinal axons rostral to a unilateral cervical spinal cord lesion in adult macaque monkey. J Comp Neurol (2007) 1.17
Synaptic destabilization by neuronal Nogo-A. Brain Cell Biol (2007) 1.17
Injury-induced alterations in CNS electrophysiology. Prog Brain Res (2007) 1.16
Red nucleus projections to distinct motor neuron pools in the rat spinal cord. J Comp Neurol (2002) 1.16
Hyperthermia following traumatic brain injury: a critical evaluation. Neurobiol Dis (2003) 1.14
Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury. Eur J Neurosci (2006) 1.14
Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice. Eur J Neurosci (2011) 1.14
Framing the evidence for health smart homes and home-based consumer health technologies as a public health intervention for independent aging: a systematic review. Int J Med Inform (2013) 1.14
Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system. Development (2010) 1.13
Combination treatment with anti-Nogo-A and chondroitinase ABC is more effective than single treatments at enhancing functional recovery after spinal cord injury. Eur J Neurosci (2013) 1.12
Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve. Neurobiol Dis (2012) 1.10
Evaluation of pharmacological treatment strategies in traumatic brain injury. Curr Pharm Des (2006) 1.10
Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury. J Neurochem (2004) 1.10
The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model. EMBO Rep (2006) 1.09
Pincher-generated Nogo-A endosomes mediate growth cone collapse and retrograde signaling. J Cell Biol (2010) 1.09