Published in Nat Med on March 21, 2004
The role of Nogo and the mitochondria-endoplasmic reticulum unit in pulmonary hypertension. Sci Transl Med (2011) 1.95
The Nogo-Nogo receptor pathway limits a spectrum of adult CNS axonal growth. J Neurosci (2006) 1.77
Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking. Cell Metab (2009) 1.76
FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression. Cell Rep (2012) 1.63
Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure. Nat Med (2015) 1.46
Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells. Proc Natl Acad Sci U S A (2006) 1.39
Mechanisms of vein graft adaptation to the arterial circulation: insights into the neointimal algorithm and management strategies. Circ J (2010) 1.39
Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair. Proc Natl Acad Sci U S A (2009) 1.27
Myoferlin is critical for endocytosis in endothelial cells. Am J Physiol Cell Physiol (2009) 1.13
Nogo-A interacts with the Nogo-66 receptor through multiple sites to create an isoform-selective subnanomolar agonist. J Neurosci (2005) 1.12
Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab (2010) 1.06
Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation. Blood (2010) 1.03
Metabolic dysfunction in pulmonary hypertension: the expanding relevance of the Warburg effect. Eur J Clin Invest (2013) 1.03
In vivo modulation of Nogo-B attenuates neointima formation. Mol Ther (2008) 1.02
A new role for the muscle repair protein dysferlin in endothelial cell adhesion and angiogenesis. Arterioscler Thromb Vasc Biol (2010) 1.01
Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation. J Exp Med (2010) 1.01
Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function. Am J Physiol Cell Physiol (2011) 0.98
Evidence supporting changes in Nogo-B levels as a marker of neointimal expansion but not adaptive arterial remodeling. Vascul Pharmacol (2006) 0.97
Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells. Hum Mol Genet (2009) 0.97
Nogo-B receptor is essential for angiogenesis in zebrafish via Akt pathway. Blood (2010) 0.96
Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects. PLoS One (2009) 0.96
Selective temporal and regional alterations of Nogo-A and small proline-rich repeat protein 1A (SPRR1A) but not Nogo-66 receptor (NgR) occur following traumatic brain injury in the rat. Exp Neurol (2006) 0.95
Reticulon 4B (Nogo-B) is a novel regulator of hepatic fibrosis. Hepatology (2011) 0.94
Nogo-A knockdown inhibits hypoxia/reoxygenation-induced activation of mitochondrial-dependent apoptosis in cardiomyocytes. J Mol Cell Cardiol (2011) 0.93
Vascular smooth muscle cell-derived adiponectin: a paracrine regulator of contractile phenotype. J Mol Cell Cardiol (2011) 0.93
Nogo-B is a new physiological substrate for MAPKAP-K2. Biochem J (2005) 0.93
Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry. J Biol Chem (2014) 0.91
Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expression. J Neurosurg (2007) 0.91
Macrophages in collateral arteriogenesis. Front Physiol (2012) 0.90
Functional outcome is impaired following traumatic brain injury in aging Nogo-A/B-deficient mice. Neuroscience (2009) 0.89
The vasculome of the mouse brain. PLoS One (2012) 0.89
The UPR and lung disease. Semin Immunopathol (2013) 0.86
Identification and regulation of reticulon 4B (Nogo-B) in renal tubular epithelial cells. Am J Pathol (2010) 0.86
Differential but competitive binding of Nogo protein and class i major histocompatibility complex (MHCI) to the PIR-B ectodomain provides an inhibition of cells. J Biol Chem (2011) 0.86
Nogo-B is associated with cytoskeletal structures in human monocyte-derived macrophages. BMC Res Notes (2011) 0.85
Genetic determinants of vascular remodelling. Can J Cardiol (2006) 0.85
Ras transformation results in cleavage of reticulon protein Nogo-B that is associated with impairment of IFN response. Cell Cycle (2015) 0.85
The role of reticulons in neurodegenerative diseases. Neuromolecular Med (2013) 0.84
The F-BAR protein NOSTRIN participates in FGF signal transduction and vascular development. EMBO J (2012) 0.84
Down-regulation of miR-206 is associated with Hirschsprung disease and suppresses cell migration and proliferation in cell models. Sci Rep (2015) 0.84
Comprehensive proteome quantification reveals NgBR as a new regulator for epithelial-mesenchymal transition of breast tumor cells. J Proteomics (2014) 0.83
Expression of NgBR is highly associated with estrogen receptor alpha and survivin in breast cancer. PLoS One (2013) 0.83
Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk. Hum Gene Ther (2012) 0.83
Nogo-B regulates migration and contraction of airway smooth muscle cells by decreasing ARPC 2/3 and increasing MYL-9 expression. Respir Res (2011) 0.82
Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology (2010) 0.81
Reticulon 4B (Nogo-B) facilitates hepatocyte proliferation and liver regeneration in mice. Hepatology (2013) 0.81
Absence of Nogo-B (reticulon 4B) facilitates hepatic stellate cell apoptosis and diminishes hepatic fibrosis in mice. Am J Pathol (2013) 0.81
Endothelial Nogo-B regulates sphingolipid biosynthesis to promote pathological cardiac hypertrophy during chronic pressure overload. JCI Insight (2016) 0.81
Nogo-A and Nogo-66 receptor in amyotrophic lateral sclerosis. J Cell Mol Med (2008) 0.80
The Nogo-B-PirB axis controls macrophage-mediated vascular remodeling. PLoS One (2013) 0.79
Impact of RTN3 deficiency on expression of BACE1 and amyloid deposition. J Neurosci (2014) 0.78
RTN4 and FBXL17 Genes are Associated with Coronary Heart Disease in Genome-Wide Association Analysis of Lithuanian Families. Balkan J Med Genet (2013) 0.78
Nogo-B receptor modulates angiogenesis response of pulmonary artery endothelial cells through eNOS coupling. Am J Respir Cell Mol Biol (2014) 0.78
An endoplasmic reticulum protein, Nogo-B, facilitates alcoholic liver disease through regulation of Kupffer cell polarization. Hepatology (2017) 0.78
Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during flow-dependent vascular remodeling. PLoS One (2012) 0.77
Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice. Dev Biol (2015) 0.77
RNT4 3'-UTR insertion/deletion polymorphisms are not associated with atrial septal defect in Chinese Han population: a brief communication. DNA Cell Biol (2012) 0.76
Identification and characterization of alternative promoters of zebrafish Rtn-4/Nogo genes in cultured cells and zebrafish embryos. Nucleic Acids Res (2010) 0.76
Schwann Cell Expressed Nogo-B Modulates Axonal Branching of Adult Sensory Neurons Through the Nogo-B Receptor NgBR. Front Cell Neurosci (2015) 0.76
cis-Prenyltransferase: New Insights into Protein Glycosylation, Rubber Synthesis, and Human Diseases. J Biol Chem (2016) 0.75
Glutamate provides a key structural contact between reticulon-4 (Nogo-66) and phosphocholine. Biochim Biophys Acta (2014) 0.75
Nogo-A regulates vascular network architecture in the postnatal brain. J Cereb Blood Flow Metab (2016) 0.75
Nogo puts the brake on vascular lesions. Nat Med (2004) 0.75
Nogo-B receptor promotes the chemoresistance of human hepatocellular carcinoma via the ubiquitination of p53 protein. Oncotarget (2016) 0.75
Nogo-B protects mice against lipopolysaccharide-induced acute lung injury. Sci Rep (2015) 0.75
Nogo-B receptor deficiency increases liver X receptor alpha nuclear translocation and hepatic lipogenesis through an adenosine monophosphate-activated protein kinase alpha-dependent pathway. Hepatology (2016) 0.75
The inflammatory protein Pentraxin 3 in cardiovascular disease. Immun Ageing (2016) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science (2002) 24.31
International network of cancer genome projects. Nature (2010) 20.35
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell (2002) 18.22
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol (2004) 16.83
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev (2002) 13.08
PRDM16 controls a brown fat/skeletal muscle switch. Nature (2008) 13.08
Prepublication data sharing. Nature (2009) 12.24
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature (2007) 11.14
Histone demethylation by a family of JmjC domain-containing proteins. Nature (2005) 10.36
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Nat Biotechnol (2009) 9.67
Role of histone H2A ubiquitination in Polycomb silencing. Nature (2004) 9.48
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell (2005) 7.75
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature (2008) 7.18
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers. Nature (2009) 6.99
A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol Cell (2007) 5.78
Regulation of p53 activity through lysine methylation. Nature (2004) 5.78
Ubiquitination regulates PTEN nuclear import and tumor suppression. Cell (2007) 5.62
PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol Cell (2002) 5.59
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell (2006) 5.54
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain. Curr Biol (2002) 5.53
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature (2006) 5.51
Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev (2002) 5.43
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell (2004) 5.37
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell (2003) 5.21
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell (2007) 5.20
Histone deimination antagonizes arginine methylation. Cell (2004) 5.19
Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Mol Cell (2004) 5.06
Evolving functions of endothelial cells in inflammation. Nat Rev Immunol (2007) 4.94
Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res (2002) 4.92
VFDB: a reference database for bacterial virulence factors. Nucleic Acids Res (2005) 4.77
Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ Res (2007) 4.72
Nitric oxide synthases: regulation and function. Eur Heart J (2011) 4.71
Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. Cancer Cell (2006) 4.55
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J (2008) 4.49
Differential exoprotease activities confer tumor-specific serum peptidome patterns. J Clin Invest (2006) 4.37
RePS: a sequence assembler that masks exact repeats identified from the shotgun data. Genome Res (2002) 4.35
Axon regeneration in young adult mice lacking Nogo-A/B. Neuron (2003) 4.23
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature (2011) 4.16
Experience-driven plasticity of visual cortex limited by myelin and Nogo receptor. Science (2005) 4.15
KaKs_Calculator: calculating Ka and Ks through model selection and model averaging. Genomics Proteomics Bioinformatics (2006) 4.15
Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase. Curr Biol (2002) 4.12
Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell (2002) 4.08
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association. Genes Dev (2002) 4.07
Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol Cell (2005) 4.04
Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis. J Clin Invest (2005) 3.95
Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol Cell Biol (2004) 3.90
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev (2008) 3.90
P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac. Cell (2002) 3.80
The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell (2007) 3.79
Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia. Cell (2004) 3.77
L3MBTL1, a histone-methylation-dependent chromatin lock. Cell (2007) 3.70
PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation. Mol Cell (2007) 3.68
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res (2005) 3.56
Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor. Science (2002) 3.50
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron (2010) 3.44
Tissue-specific contributions of pneumococcal virulence factors to pathogenesis. J Infect Dis (2004) 3.43
Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Mol Cell (2006) 3.39
An iron delivery pathway mediated by a lipocalin. Mol Cell (2002) 3.38
Memory impairment in transgenic Alzheimer mice requires cellular prion protein. J Neurosci (2010) 3.36
An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers. Neuron (2009) 3.34