Published in J Neurosci on October 17, 2007
GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophrenia. Schizophr Bull (2008) 2.81
Lower expression of glutamic acid decarboxylase 67 in the prefrontal cortex in schizophrenia: contribution of altered regulation by Zif268. Am J Psychiatry (2014) 2.46
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci (2015) 2.43
Histone methylation regulates memory formation. J Neurosci (2010) 2.30
Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders. Curr Opin Pharmacol (2008) 2.29
Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc Natl Acad Sci U S A (2010) 2.06
Isolation of neuronal chromatin from brain tissue. BMC Neurosci (2008) 2.02
A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. Hum Mol Genet (2008) 1.87
Alterations of cortical GABA neurons and network oscillations in schizophrenia. Curr Psychiatry Rep (2010) 1.87
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci U S A (2008) 1.74
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Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. J Neurosci (2011) 1.61
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GABA neuron alterations, cortical circuit dysfunction and cognitive deficits in schizophrenia. Neural Plast (2011) 1.51
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Epigenetic GABAergic targets in schizophrenia and bipolar disorder. Neuropharmacology (2010) 1.41
Deficits in transcriptional regulators of cortical parvalbumin neurons in schizophrenia. Am J Psychiatry (2012) 1.40
The dynamics of DNA methylation in schizophrenia and related psychiatric disorders. Neuropsychopharmacology (2012) 1.40
Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B. J Neurosci (2010) 1.33
Association between SNPs and gene expression in multiple regions of the human brain. Transl Psychiatry (2012) 1.27
Epigenetics of major psychosis: progress, problems and perspectives. Trends Genet (2012) 1.24
The reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexes. Mol Pharmacol (2008) 1.22
Histone modifications, DNA methylation, and schizophrenia. Neurosci Biobehav Rev (2009) 1.17
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Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis. Neuropsychopharmacology (2011) 1.17
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Balancing histone methylation activities in psychiatric disorders. Trends Mol Med (2011) 1.14
Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia. Mol Psychiatry (2012) 1.14
Inhibitory neurons in human cortical circuits: substrate for cognitive dysfunction in schizophrenia. Curr Opin Neurobiol (2013) 1.13
Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes. Neuropsychopharmacology (2009) 1.12
Altered parvalbumin basket cell inputs in the dorsolateral prefrontal cortex of schizophrenia subjects. Mol Psychiatry (2013) 1.11
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Cortical opioid markers in schizophrenia and across postnatal development. Cereb Cortex (2011) 1.06
Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. PLoS Genet (2013) 1.05
Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT. Neuropsychopharmacology (2010) 1.02
Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures. J Psychiatry Neurosci (2009) 0.99
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Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia. Schizophr Bull (2010) 0.98
Lower glutamic acid decarboxylase 65-kDa isoform messenger RNA and protein levels in the prefrontal cortex in schizoaffective disorder but not schizophrenia. Biol Psychiatry (2014) 0.98
Maternal immune activation alters behavior in adult offspring, with subtle changes in the cortical transcriptome and epigenome. Schizophr Res (2012) 0.97
Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain. Mol Pharmacol (2011) 0.97
The genome in three dimensions: a new frontier in human brain research. Biol Psychiatry (2013) 0.96
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Loss-of-function variants in schizophrenia risk and SETD1A as a candidate susceptibility gene. Neuron (2014) 0.96
Postnatal development of synaptic structure proteins in pyramidal neuron axon initial segments in monkey prefrontal cortex. J Comp Neurol (2009) 0.95
White matter neuron alterations in schizophrenia and related disorders. Int J Dev Neurosci (2010) 0.94
Methamphetamine-associated memory is regulated by a writer and an eraser of permissive histone methylation. Biol Psychiatry (2013) 0.94
Epigenetics-beyond the genome in alcoholism. Alcohol Res (2012) 0.94
Regulation of histone H3K4 methylation in brain development and disease. Philos Trans R Soc Lond B Biol Sci (2014) 0.94
How the epigenome contributes to the development of psychiatric disorders. Dev Psychobiol (2010) 0.92
Histone deacetylase inhibition alters histone methylation associated with heat shock protein 70 promoter modifications in astrocytes and neurons. Neuropharmacology (2010) 0.92
WNK signaling is involved in neural development via Lhx8/Awh expression. PLoS One (2013) 0.91
Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex. Proc Natl Acad Sci U S A (2010) 0.91
Update on the neurobiology of schizophrenia: a role for extracellular microdomains. Minerva Psichiatr (2012) 0.91
Pharmacology of epigenetics in brain disorders. Br J Pharmacol (2009) 0.90
Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. J Neurosci (2013) 0.90
Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol Psychiatry (2013) 0.89
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Epigenetic Basis of Mental Illness. Neuroscientist (2015) 0.89
Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia. Front Behav Neurosci (2013) 0.89
DNA methylation in schizophrenia: progress and challenges of epigenetic studies. Genome Med (2012) 0.89
Epigenetic determinants of healthy and diseased brain aging and cognition. JAMA Neurol (2013) 0.88
Sensitive periods in epigenetics: bringing us closer to complex behavioral phenotypes. Epigenomics (2012) 0.87
Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors. Eur Arch Psychiatry Clin Neurosci (2013) 0.87
Gene expression in superior temporal cortex of schizophrenia patients. Eur Arch Psychiatry Clin Neurosci (2013) 0.86
Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain. Transl Psychiatry (2015) 0.85
Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: relevance for the study of chromatin remodeling properties of antipsychotic drugs. Transl Psychiatry (2016) 0.85
Transcriptional regulation of GAD1 GABA synthesis gene in the prefrontal cortex of subjects with schizophrenia. Schizophr Res (2014) 0.85
Epigenetic mechanisms in schizophrenia. Dialogues Clin Neurosci (2014) 0.85
Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains. Hum Mol Genet (2014) 0.85
The HDAC Inhibitor Phenylbutyrate Reverses Effects of Neonatal Ventral Hippocampal Lesion in Rats. Front Psychiatry (2011) 0.85
Epigenetics and sex differences in the brain: A genome-wide comparison of histone-3 lysine-4 trimethylation (H3K4me3) in male and female mice. Exp Neurol (2014) 0.84
Translational potential of olfactory mucosa for the study of neuropsychiatric illness. Transl Psychiatry (2015) 0.84
Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits. Dev Psychopathol (2012) 0.83
Reversible histone methylation regulates brain gene expression and behavior. Horm Behav (2010) 0.83
Layer 3 Excitatory and Inhibitory Circuitry in the Prefrontal Cortex: Developmental Trajectories and Alterations in Schizophrenia. Biol Psychiatry (2016) 0.83
Interneuron epigenomes during the critical period of cortical plasticity: Implications for schizophrenia. Neurobiol Learn Mem (2015) 0.83
Tipping the lysine methylation balance in disease. Biopolymers (2013) 0.82
Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain. Toxicol Appl Pharmacol (2015) 0.82
Cortical Gene Expression After a Conditional Knockout of 67 kDa Glutamic Acid Decarboxylase in Parvalbumin Neurons. Schizophr Bull (2016) 0.81
A chromatin assay for human brain tissue. J Vis Exp (2008) 0.81
Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory. J Neurosci (2015) 0.81
Altered Markers of Cortical γ-Aminobutyric Acid Neuronal Activity in Schizophrenia: Role of the NARP Gene. JAMA Psychiatry (2015) 0.81
Treatment-resistant schizophrenia: current insights on the pharmacogenomics of antipsychotics. Pharmgenomics Pers Med (2016) 0.80
Markedly Lower Glutamic Acid Decarboxylase 67 Protein Levels in a Subset of Boutons in Schizophrenia. Biol Psychiatry (2015) 0.80
Proteomic investigation of epigenetics in neuropsychiatric disorders: a missing link between genetics and behavior? J Proteome Res (2010) 0.80
Fgfr1 inactivation in the mouse telencephalon results in impaired maturation of interneurons expressing parvalbumin. PLoS One (2014) 0.79
Epigenetic management of major psychosis. Clin Epigenetics (2011) 0.79
Long-term effects of early-life caregiving experiences on brain-derived neurotrophic factor histone acetylation in the adult rat mPFC. Stress (2015) 0.79
Spatial genome organization and cognition. Nat Rev Neurosci (2016) 0.78
Emerging roles of epigenetic mechanisms in Parkinson's disease. Funct Integr Genomics (2011) 0.78
The epigenomics of schizophrenia, in the mouse. Am J Med Genet B Neuropsychiatr Genet (2017) 0.77
Schizophrenia and birthplace of paternal and maternal grandfather in the Jerusalem perinatal cohort prospective study. Schizophr Res (2009) 0.77
Chromatin-bound RNA and the neurobiology of psychiatric disease. Neuroscience (2013) 0.77
Genetic and epigenetic factors underlying sex differences in the regulation of gene expression in the brain. J Neurosci Res (2017) 0.76
The 2nd Schizophrenia International Research Society Conference, 10-14 April 2010, Florence, Italy: summaries of oral sessions. Schizophr Res (2010) 0.76
Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders. Front Cell Neurosci (2016) 0.76
REM sleep and its Loss-Associated Epigenetic Regulation with Reference to Noradrenaline in Particular. Curr Neuropharmacol (2016) 0.76
Practical Guidelines for High-Resolution Epigenomic Profiling of Nucleosomal Histones in Postmortem Human Brain Tissue. Biol Psychiatry (2016) 0.76
Essential role for Nix in autophagic maturation of erythroid cells. Nature (2008) 6.49
Prevalence and test characteristics of national health safety network ventilator-associated events. Crit Care Med (2014) 3.46
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons. PLoS One (2007) 3.30
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proc Natl Acad Sci U S A (2002) 3.29
Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol Psychiatry (2006) 3.00
Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development. J Biol Chem (2006) 2.39
The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development (2003) 2.38
DNA replication origins fire stochastically in fission yeast. Mol Biol Cell (2005) 2.35
Histone methylation regulates memory formation. J Neurosci (2010) 2.30
Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc Natl Acad Sci U S A (2010) 2.06
Isolation of neuronal chromatin from brain tissue. BMC Neurosci (2008) 2.02
Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91
The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation. J Neurosci (2007) 1.90
A set of differentially expressed miRNAs, including miR-30a-5p, act as post-transcriptional inhibitors of BDNF in prefrontal cortex. Hum Mol Genet (2008) 1.87
Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons. Arch Gen Psychiatry (2011) 1.81
Ammonia and carbon dioxide concentrations in disposable and reusable ventilated mouse cages. J Am Assoc Lab Anim Sci (2008) 1.75
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Molecular determinants of dysregulated GABAergic gene expression in the prefrontal cortex of subjects with schizophrenia. Biol Psychiatry (2009) 1.71
GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophrenia. PLoS One (2007) 1.66
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Chromatin immunoprecipitation in postmortem brain. J Neurosci Methods (2006) 1.43
Drug-induced activation of dopamine D(1) receptor signaling and inhibition of class I/II histone deacetylase induce chromatin remodeling in reward circuitry and modulate cocaine-related behaviors. Neuropsychopharmacology (2008) 1.38
Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B. J Neurosci (2010) 1.33
The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism. PLoS One (2010) 1.32
Histone methylation at gene promoters is associated with developmental regulation and region-specific expression of ionotropic and metabotropic glutamate receptors in human brain. J Neurochem (2005) 1.27
Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling. J Neurochem (2004) 1.25
Neuronal nuclei isolation from human postmortem brain tissue. J Vis Exp (2008) 1.24
Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice. Development (2004) 1.21
Human CD4+ T cell epitopes from vaccinia virus induced by vaccination or infection. PLoS Pathog (2007) 1.20
Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice. J Neurobiol (2006) 1.18
Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophrenia. Arch Gen Psychiatry (2005) 1.17
NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis. Learn Mem (2006) 1.16
Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation. J Am Soc Nephrol (2012) 1.16
DNA methylation changes in schizophrenia and bipolar disorder. Epigenetics (2008) 1.15
Developmental regulation of Eed complex composition governs a switch in global histone modification in brain. J Biol Chem (2007) 1.15
Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development (2004) 1.14
Balancing histone methylation activities in psychiatric disorders. Trends Mol Med (2011) 1.14
Hyperspectral imaging for early detection of oxygenation and perfusion changes in irradiated skin. J Biomed Opt (2012) 1.13
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Arch Gen Psychiatry (2002) 1.10
Leukoaraiosis predicts poor 90-day outcome after acute large cerebral artery occlusion. Cerebrovasc Dis (2012) 1.08
The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development. Cell Stem Cell (2012) 1.08
Epigenetics in the human brain. Neuropsychopharmacology (2012) 1.08
Human-specific histone methylation signatures at transcription start sites in prefrontal neurons. PLoS Biol (2012) 1.08
Flat-panel digital mammography system: contrast-detail comparison between screen-film radiographs and hard-copy images. Radiology (2002) 1.08
Chromatin protein L3MBTL1 is dispensable for development and tumor suppression in mice. J Biol Chem (2010) 1.06
Juxtaposed Polycomb complexes co-regulate vertebral identity. Development (2006) 1.06
Coordinated cell type-specific epigenetic remodeling in prefrontal cortex begins before birth and continues into early adulthood. PLoS Genet (2013) 1.05
Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med (2013) 1.04
Adult intestinal intussusception: can abdominal MDCT distinguish an intussusception caused by a lead point? Abdom Imaging (2008) 1.04
Dihydropyridine receptors and type 1 ryanodine receptors constitute the molecular machinery for voltage-induced Ca2+ release in nerve terminals. J Neurosci (2006) 1.02
Low risk of ureteral obstruction with "deep" (dorsal/posterior) uterosacral ligament suture placement for transvaginal apical suspension. Am J Obstet Gynecol (2005) 1.01
The Polycomb-group gene eed regulates thymocyte differentiation and suppresses the development of carcinogen-induced T-cell lymphomas. Oncogene (2002) 0.99
Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia. Schizophr Bull (2010) 0.98
Maternal immune activation alters behavior in adult offspring, with subtle changes in the cortical transcriptome and epigenome. Schizophr Res (2012) 0.97
β3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation. J Biol Chem (2012) 0.96
Ca(2+) spark sites in smooth muscle cells are numerous and differ in number of ryanodine receptors, large-conductance K(+) channels, and coupling ratio between them. Am J Physiol Cell Physiol (2004) 0.96
Ammonia and carbon dioxide concentrations in disposable and reusable static mouse cages. Lab Anim (NY) (2009) 0.95
White matter neuron alterations in schizophrenia and related disorders. Int J Dev Neurosci (2010) 0.94
Antiadrenergic and hemodynamic effects of ranolazine in conscious dogs. J Cardiovasc Pharmacol (2011) 0.92
Long-term statin therapy and CSF cholesterol levels: implications for Alzheimer's disease. Dement Geriatr Cogn Disord (2009) 0.91
Cholangitis: a histologic classification based on patterns of injury in liver biopsies. Pathol Res Pract (2005) 0.91
Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia. J Neurosci (2013) 0.90
Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease. Neurobiol Dis (2011) 0.90
Cingulate white matter neurons in schizophrenia and bipolar disorder. Biol Psychiatry (2009) 0.90
The molecular circuitry regulating the switch between iron deficiency and overload in mice. J Biol Chem (2006) 0.89
Prefrontal cortical dysfunction after overexpression of histone deacetylase 1. Biol Psychiatry (2013) 0.89
A major locus on mouse chromosome 18 controls XX sex reversal in Odd Sex (Ods) mice. Hum Mol Genet (2003) 0.89
Recombinant human thrombomodulin inhibits arterial neointimal hyperplasia after balloon injury. J Vasc Surg (2004) 0.88
Determination of cystic duct patency using hepatobiliary MRI with gadoxetate disodium: is T1 precontrast imaging necessary? J Magn Reson Imaging (2011) 0.87
Epigenetic dysregulation in schizophrenia: molecular and clinical aspects of histone deacetylase inhibitors. Eur Arch Psychiatry Clin Neurosci (2013) 0.87
Advancing drug discovery for schizophrenia. Ann N Y Acad Sci (2011) 0.86
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Synthesis and pharmacokinetic characterization of a pH-sensitive polyethylene glycol ginsenoside CK (PEG-CK) conjugate. Biosci Biotechnol Biochem (2014) 0.85
Stretch responses of cutaneous RA afferent neurons in mouse hairy skin. J Neurophysiol (2002) 0.83
The histone deacetylase inhibitor, sodium butyrate, alleviates cognitive deficits in pre-motor stage PD. Neuropharmacology (2012) 0.83
Midline anterior repair alone vs anterior repair plus vaginal paravaginal repair: a comparison of anatomic and quality of life outcomes. Int Urogynecol J Pelvic Floor Dysfunct (2006) 0.83
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A self-assessment survey of the Institutional Animal Care and Use Committee, Part 1: animal welfare and protocol compliance. Lab Anim (NY) (2012) 0.83
N6-substituted C5'-modified adenosines as A1 adenosine receptor agonists. Bioorg Med Chem (2007) 0.83
Statins differentially affect amyloid precursor protein metabolism in presymptomatic PS1 and non-PS1 subjects. Arch Neurol (2007) 0.83
Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals. Neurobiol Dis (2002) 0.82
Impact of alcohol-based, waterless hand antiseptic on the incidence of infection and colonization with methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci. Infect Control Hosp Epidemiol (2006) 0.82
Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate. Neurosci Lett (2009) 0.82
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Potency matters: thresholds govern endocrine activity. Regul Toxicol Pharmacol (2013) 0.80
RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. Autism Res (2010) 0.79