Published in Development on June 01, 1991
An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics (1999) 5.87
Preferential transposition of Drosophila P elements to nearby chromosomal sites. Genetics (1993) 3.67
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP. Genes Dev (1999) 3.05
Origins of immunity: Relish, a compound Rel-like gene in the antibacterial defense of Drosophila. Proc Natl Acad Sci U S A (1996) 2.99
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J (1995) 2.48
A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast. Mol Biol Cell (1992) 2.33
The NF-kappa B p50 precursor, p105, contains an internal I kappa B-like inhibitor that preferentially inhibits p50. EMBO J (1992) 2.19
A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF. EMBO J (1999) 1.99
Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol Biol Cell (2000) 1.98
In vivo modulation of morphogenetic movements in Drosophila embryos with femtosecond laser pulses. Proc Natl Acad Sci U S A (2005) 1.96
Analysis of the Drosophila host defense in domino mutant larvae, which are devoid of hemocytes. Proc Natl Acad Sci U S A (1998) 1.73
Dissociation of the dorsal-cactus complex and phosphorylation of the dorsal protein correlate with the nuclear localization of dorsal. J Cell Biol (1993) 1.70
Sulfation of eggshell components by Pipe defines dorsal-ventral polarity in the Drosophila embryo. Curr Biol (2009) 1.64
Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans. Genetics (1993) 1.58
A genetic analysis of pannier, a gene necessary for viability of dorsal tissues and bristle positioning in Drosophila. Genetics (1996) 1.30
Dorsal, a Drosophila Rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll. Mol Cell Biol (1994) 1.28
Melanotic mutants in Drosophila: pathways and phenotypes. Genetics (2006) 1.26
Evolutionary conserved regulation of HIF-1β by NF-κB. PLoS Genet (2011) 1.22
The same dorsal binding site mediates both activation and repression in a context-dependent manner. EMBO J (1992) 1.19
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B. Mol Biol Cell (1993) 1.18
In vivo self-association of the Drosophila rel-protein dorsal. Proc Natl Acad Sci U S A (1992) 1.16
Tube Is an IRAK-4 homolog in a Toll pathway adapted for development and immunity. J Innate Immun (2009) 1.14
Genetic characterization of tube and pelle, genes required for signaling between Toll and dorsal in the specification of the dorsal-ventral pattern of the Drosophila embryo. Genetics (1993) 1.13
Ventralization of the Drosophila embryo by deletion of extracellular leucine-rich repeats in the Toll protein. Mol Biol Cell (1995) 1.13
NF-kappaB, IkappaB, and IRAK control glutamate receptor density at the Drosophila NMJ. Neuron (2007) 1.07
Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes. J Cell Sci (2009) 1.06
Evolution of insect dorsoventral patterning mechanisms. Cold Spring Harb Symp Quant Biol (2009) 1.06
Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation. Genes Dev (1999) 1.05
An in vivo RNA interference screen identifies gene networks controlling Drosophila melanogaster blood cell homeostasis. BMC Dev Biol (2010) 1.05
Conservation of enhancer location in divergent insects. Proc Natl Acad Sci U S A (2009) 1.03
A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo. Genes Dev (1997) 1.03
Disulfide cross-linking in crude embryonic lysates reveals three complexes of the Drosophila morphogen dorsal and its inhibitor cactus. Proc Natl Acad Sci U S A (1994) 1.01
The vrille gene of Drosophila is a maternal enhancer of decapentaplegic and encodes a new member of the bZIP family of transcription factors. Genetics (1997) 1.01
Regulated nuclear import of the Drosophila rel protein dorsal: structure-function analysis. Mol Cell Biol (1996) 0.95
The maternal nudel protein of Drosophila has two distinct roles important for embryogenesis. Genetics (1996) 0.94
Regulation of Toll signaling and inflammation by β-arrestin and the SUMO protease Ulp1. Genetics (2013) 0.92
Domain mapping of tube, a protein essential for dorsoventral patterning of the Drosophila embryo. EMBO J (1993) 0.92
The thick veins gene of Drosophila is required for dorsoventral polarity of the embryo. Genetics (1994) 0.86
Distinct functional specificities are associated with protein isoforms encoded by the Drosophila dorsal-ventral patterning gene pipe. Development (2009) 0.86
Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes. Elife (2015) 0.82
The cyclope gene of Drosophila encodes a cytochrome c oxidase subunit VIc homolog. Genetics (2001) 0.82
Notch and PKC are involved in formation of the lateral region of the dorso-ventral axis in Drosophila embryos. PLoS One (2013) 0.81
Ehrlichia chaffeensis infections in Drosophila melanogaster. Infect Immun (2009) 0.80
The IRAK homolog Pelle is the functional counterpart of IκB kinase in the Drosophila Toll pathway. PLoS One (2013) 0.80
Relocalization of Drosophila dorsal protein can be induced by a rise in cytoplasmic calcium concentration and the expression of constitutively active but not wild-type Toll receptors. Biochem J (1993) 0.80
Maternal control of the Drosophila dorsal-ventral body axis. Wiley Interdiscip Rev Dev Biol (2014) 0.78
Dynamic BMP signaling polarized by Toll patterns the dorsoventral axis in a hemimetabolous insect. Elife (2015) 0.78
Toll pathway modulates TNF-induced JNK-dependent cell death in Drosophila. Open Biol (2015) 0.78
Alcohol resistance in Drosophila is modulated by the Toll innate immune pathway. Genes Brain Behav (2016) 0.78
Calpain A modulates Toll responses by limited Cactus/IκB proteolysis. Mol Biol Cell (2013) 0.77
The presence of nuclear cactus in the early Drosophila embryo may extend the dynamic range of the dorsal gradient. PLoS Comput Biol (2015) 0.75
The Friend of GATA Transcriptional Co-Regulator, U-Shaped, Is a Downstream Antagonist of Dorsal-Driven Prohemocyte Differentiation in Drosophila. PLoS One (2016) 0.75
Multipotent versus differentiated cell fate selection in the developing Drosophila airways. Elife (2015) 0.75
A novel function for Cactus/IκB inhibitor to promote Dl nuclear localization and activity in the Drosophila embryo. Development (2017) 0.75
Mutations affecting segment number and polarity in Drosophila. Nature (1980) 18.72
The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. Development (1996) 8.87
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell (1988) 7.72
The origin of pattern and polarity in the Drosophila embryo. Cell (1992) 7.40
A gradient of bicoid protein in Drosophila embryos. Cell (1988) 7.30
Control elements of the Drosophila segmentation gene fushi tarazu. Cell (1985) 4.83
The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo. Nature (1989) 4.81
sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell (1998) 4.40
The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. EMBO J (1988) 4.19
A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo. Cell (1989) 4.17
The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells. Development (1997) 4.14
Staufen, a gene required to localize maternal RNAs in the Drosophila egg. Cell (1991) 4.10
Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate. Curr Biol (1994) 4.05
Genetic control and evolution of sexually dimorphic characters in Drosophila. Nature (2000) 3.92
Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell (1987) 3.91
Homeotic genes and the homeobox. Annu Rev Genet (1986) 3.60
The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Proc Natl Acad Sci U S A (1994) 3.31
Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product. Cell (1985) 3.24
Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development (1996) 3.21
Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen. Nature (1989) 3.15
Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. Development (1996) 3.15
no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. Development (1994) 3.14
Staufen protein associates with the 3'UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner. Cell (1994) 3.02
A fate map for the larval epidermis of Drosophila melanogaster: localized cuticle defects following irradiation of the blastoderm with an ultraviolet laser microbeam. Dev Biol (1979) 2.98
The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates. Cell (1990) 2.83
Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in Drosophila. Cell (1986) 2.81
The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. Development (1992) 2.76
Information for the dorsal--ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature (1984) 2.60
fork head domain genes in zebrafish. Dev Genes Evol (1998) 2.58
Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. Development (1996) 2.54
Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte. Development (1989) 2.50
Cadherins in embryonic and neural morphogenesis. Nat Rev Mol Cell Biol (2000) 2.41
A radiation hybrid map of the zebrafish genome. Nat Genet (1999) 2.31
Characterization of zebrafish mutants with defects in embryonic hematopoiesis. Development (1996) 2.29
Expression and function of the segmentation gene fushi tarazu during Drosophila neurogenesis. Science (1988) 2.23
Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product. Cell (1985) 2.22
DE-Cadherin is required for intercellular motility during Drosophila oogenesis. J Cell Biol (1999) 2.18
The molecular motor dynein is involved in targeting swallow and bicoid RNA to the anterior pole of Drosophila oocytes. Nat Cell Biol (2000) 2.17
Zebrafish pigmentation mutations and the processes of neural crest development. Development (1996) 2.14
Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development (1996) 2.13
RNA-RNA interaction is required for the formation of specific bicoid mRNA 3' UTR-STAUFEN ribonucleoprotein particles. EMBO J (1997) 2.13
Zebrafish pea3 and erm are general targets of FGF8 signaling. Curr Biol (2001) 2.13
cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates. Cell (1992) 2.12
The Drosophila gene torso encodes a putative receptor tyrosine kinase. Nature (1989) 2.12
Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo. Nature (1994) 2.10
Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activity. Genes Dev (2000) 2.09
Genetic analysis of vertebrate sensory hair cell mechanosensation: the zebrafish circler mutants. Neuron (1998) 2.07
The Drosophila Netrin receptor Frazzled guides axons by controlling Netrin distribution. Nature (2000) 2.07
A dorso-ventral shift of embryonic primordia in a new maternal-effect mutant of Drosophila. Nature (1980) 2.06
The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo. Development (1991) 2.03
Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development (1996) 1.97
Zebrafish vasa RNA but not its protein is a component of the germ plasm and segregates asymmetrically before germline specification. J Cell Biol (2000) 1.95
Origin and development of the zebrafish endoderm. Development (1999) 1.94
The control of cell fate along the dorsal-ventral axis of the Drosophila embryo. Development (1991) 1.93
hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo. Dev Biol (1987) 1.90
Function of torso in determining the terminal anlagen of the Drosophila embryo. Nature (1988) 1.88
Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. Development (1999) 1.84
Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (1997) 1.84
Jaw and branchial arch mutants in zebrafish I: branchial arches. Development (1996) 1.84
Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development (1996) 1.81
Translational repression determines a neuronal potential in Drosophila asymmetric cell division. Nature (2001) 1.80
dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. Development (1996) 1.78
High-frequency germ-line transmission of plasmid DNA sequences injected into fertilized zebrafish eggs. Proc Natl Acad Sci U S A (1991) 1.73
Genetic analysis of fin formation in the zebrafish, Danio rerio. Development (1996) 1.71
Mutations affecting development of the zebrafish inner ear and lateral line. Development (1996) 1.70
The polarity of the dorsoventral axis in the Drosophila embryo is defined by an extracellular signal. Cell (1991) 1.69
Jaw and branchial arch mutants in zebrafish II: anterior arches and cartilage differentiation. Development (1996) 1.67
The dissociation of nuclear and centrosomal division in gnu, a mutation causing giant nuclei in Drosophila. Cell (1986) 1.65
Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development (1996) 1.65
Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos. Development (1994) 1.57
A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo. Genes Dev (1988) 1.57
Neural degeneration mutants in the zebrafish, Danio rerio. Development (1996) 1.53
Multiple extracellular activities in Drosophila egg perivitelline fluid are required for establishment of embryonic dorsal-ventral polarity. Cell (1992) 1.51
Genes affecting the segmental subdivision of the Drosophila embryo. Cold Spring Harb Symp Quant Biol (1985) 1.51
Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg. Cell (1992) 1.48
Zebrafish mutations affecting retinotectal axon pathfinding. Development (1996) 1.47
Cofilin/ADF is required for cell motility during Drosophila ovary development and oogenesis. Nat Cell Biol (2001) 1.45
The endoderm plays an important role in patterning the segmented pharyngeal region in zebrafish (Danio rerio). Dev Biol (2000) 1.44
The genetics of the dorsal-Bicaudal-D region of Drosophila melanogaster. Genetics (1986) 1.41
Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen. Development (1990) 1.40
Rescue of bicoid mutant Drosophila embryos by bicoid fusion proteins containing heterologous activating sequences. Nature (1989) 1.40
Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal. Mech Dev (1999) 1.39
The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants. Genes Dev (1992) 1.37
Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain. Development (1996) 1.34
A sponge-like structure involved in the association and transport of maternal products during Drosophila oogenesis. J Cell Biol (1997) 1.33
Germline transformation with Drosophila mutant actin genes induces constitutive expression of heat shock genes. Cell (1986) 1.33
Large scale genetics in a small vertebrate, the zebrafish. Int J Dev Biol (1996) 1.29
Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. Development (1996) 1.29
Mutations affecting xanthophore pigmentation in the zebrafish, Danio rerio. Development (1996) 1.27
Mutational approaches to studying embryonic pattern formation in the zebrafish. Curr Opin Genet Dev (1993) 1.27
Mutations affecting pigmentation and shape of the adult zebrafish. Dev Genes Evol (1996) 1.24
The zebrafish epiboly mutants. Development (1996) 1.24
Molecular characterization of mutant actin genes which induce heat-shock proteins in Drosophila flight muscles. EMBO J (1986) 1.23
Zebrafish touch-insensitive mutants reveal an essential role for the developmental regulation of sodium current. J Neurosci (1998) 1.21
The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. Dev Biol (1997) 1.20
A mutation in the zebrafish maternal-effect gene nebel affects furrow formation and vasa RNA localization. Curr Biol (2000) 1.19
Lineage, migration, and morphogenesis of longitudinal glia in the Drosophila CNS as revealed by a molecular lineage marker. Neuron (1989) 1.19
A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila. Mech Dev (1996) 1.18
Genetic dissection of the retinotectal projection. Development (1996) 1.13