Published in Mol Biotechnol on October 18, 2007
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Chromosome-wide analysis of protein binding and modifications. Methods Mol Biol (2009) 0.75
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DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. Nat Genet (2002) 3.25
Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection. Nat Struct Mol Biol (2007) 2.87
Negative and positive regulation of gene expression by mouse histone deacetylase 1. Mol Cell Biol (2006) 2.28
Immunoprecipitation of native chromatin: NChIP. Methods (2003) 2.27
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. EMBO J (2003) 2.21
Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells. Cancer Res (2004) 1.89
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site. Cancer Res (2007) 1.77
Epigenetic reprogramming and imprinting in origins of disease. Rev Endocr Metab Disord (2007) 1.75
Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene. Nucleic Acids Res (2007) 1.59
Methylation-sensitive single-nucleotide primer extension (Ms-SNuPE) for quantitative measurement of DNA methylation. Nat Protoc (2007) 1.16
Attenuated DNA damage repair by trichostatin A through BRCA1 suppression. Radiat Res (2007) 1.13
Functional proteomics in histone research and epigenetics. Expert Rev Proteomics (2007) 1.04
Gametes and embryo epigenetic reprogramming affect developmental outcome: implication for assisted reproductive technologies. Pediatr Res (2005) 1.02
Restriction landmark genomic scanning. Nat Protoc (2006) 0.92
Methylation-sensitive single-strand conformation analysis: a rapid method to screen for and analyze DNA methylation. Methods Mol Biol (2004) 0.86
Targeting aberrant chromatin structure in colorectal carcinomas. Cancer J (2007) 0.84
Tracking chromatin states using controlled DNase I treatment and real-time PCR. Cell Mol Biol Lett (2007) 0.81
Regulation of the human catalytic subunit of telomerase (hTERT). Gene (2012) 1.81
The impact of metabolism on DNA methylation. Hum Mol Genet (2005) 1.66
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS One (2010) 1.61
Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis. Am J Respir Cell Mol Biol (2008) 1.58
Aging, cancer and nutrition: the DNA methylation connection. Mech Ageing Dev (2003) 1.53
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts. Mol Cell Biochem (2003) 1.45
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG. J Cell Biochem (2008) 1.39
Relationships between the posterior interosseous nerve and the supinator muscle: application to peripheral nerve compression syndromes and nerve transfer procedures. J Neurol Surg A Cent Eur Neurosurg (2013) 1.38
Epigenetic targets of bioactive dietary components for cancer prevention and therapy. Clin Epigenetics (2010) 1.33
Epigenetic diet: impact on the epigenome and cancer. Epigenomics (2011) 1.33
Gene-environment interactions and epigenetic basis of human diseases. Curr Issues Mol Biol (2008) 1.31
Epigenetic regulation of thy-1 by histone deacetylase inhibitor in rat lung fibroblasts. Am J Respir Cell Mol Biol (2010) 1.29
Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer (2009) 1.26
Genetic and epigenetic modulation of telomerase activity in development and disease. Gene (2004) 1.25
Analysis of telomerase activity and detection of its catalytic subunit, hTERT. Anal Biochem (2003) 1.23
DNA methylation impacts on learning and memory in aging. Neurobiol Aging (2007) 1.20
Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation. Genes Chromosomes Cancer (2004) 1.19
Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer. Mol Cancer (2013) 1.17
EGCG down-regulates telomerase in human breast carcinoma MCF-7 cells, leading to suppression of cell viability and induction of apoptosis. Int J Oncol (2004) 1.15
Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression. FASEB J (2009) 1.14
Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells. Mol Cancer (2010) 1.11
Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation. Mol Cancer Ther (2004) 1.10
Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice. Carcinogenesis (2010) 1.07
Polyphenols and aging. Curr Aging Sci (2010) 1.06
Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements. Gene (2003) 1.06
Assessment of telomere length and factors that contribute to its stability. Eur J Biochem (2003) 1.04
Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications. PLoS One (2012) 1.02
DNA methylation detection: bisulfite genomic sequencing analysis. Methods Mol Biol (2011) 1.02
Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells. Biochem Biophys Res Commun (2003) 1.01
Epigenetic regulation of caloric restriction in aging. BMC Med (2011) 0.99
EGCG inhibits mammary cancer cell migration through inhibition of nitric oxide synthase and guanylate cyclase. Biochem Biophys Res Commun (2008) 0.99
Mitochondrial regulation of epigenetics and its role in human diseases. Epigenetics (2012) 0.98
Epigenetic control of telomerase and modes of telomere maintenance in aging and abnormal systems. Front Biosci (2005) 0.98
A novel prodrug of epigallocatechin-3-gallate: differential epigenetic hTERT repression in human breast cancer cells. Cancer Prev Res (Phila) (2011) 0.97
Profiling DNA methylation by bisulfite genomic sequencing: problems and solutions. Methods Mol Biol (2004) 0.96
MicroRNAs: an emerging science in cancer epigenetics. J Clin Bioinforma (2013) 0.94
p16(INK4a) suppression by glucose restriction contributes to human cellular lifespan extension through SIRT1-mediated epigenetic and genetic mechanisms. PLoS One (2011) 0.94
Strategies targeting telomerase inhibition. Mol Biotechnol (2008) 0.94
Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells. Anticancer Res (2009) 0.92
The low-toxicity 9-cis UAB30 novel retinoid down-regulates the DNA methyltransferases and has anti-telomerase activity in human breast cancer cells. Int J Oncol (2007) 0.92
Insufficient DNA methylation affects healthy aging and promotes age-related health problems. Clin Epigenetics (2011) 0.90
Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation. Exp Cell Res (2013) 0.90
Epigenomics of ovarian cancer and its chemoprevention. Front Genet (2011) 0.89
2D difference gel electrophoresis analysis of different time points during the course of neoplastic transformation of human mammary epithelial cells. J Proteome Res (2010) 0.89
Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells. Int J Oncol (2008) 0.88
Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein. PLoS One (2013) 0.87
The Novel Retinoid, 9cUAB30, Inhibits Telomerase and Induces Apoptosis in HL60 Cells. Transl Oncol (2008) 0.87
Telomerase, telomerase inhibition, and cancer. J Anti Aging Med (2003) 0.86
Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop. Exp Cell Res (2006) 0.86
Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis. J Cell Physiol (2014) 0.84
Combined chromatin immunoprecipitation and bisulfite methylation sequencing analysis. Methods Mol Biol (2011) 0.84
Aging cell culture: methods and observations. Methods Mol Biol (2007) 0.83
Impact of epigenetic dietary compounds on transgenerational prevention of human diseases. AAPS J (2013) 0.81
Retinoid-induced histone deacetylation inhibits telomerase activity in estrogen receptor-negative breast cancer cells. Anticancer Res (2009) 0.81
A method to study the expression of DNA methyltransferases in aging systems in vitro. Methods Mol Biol (2007) 0.80
RNA interference using a plasmid construct expressing short-hairpin RNA. Methods Mol Biol (2007) 0.80
hTERT knockdown in human embryonic kidney cells using double-stranded RNA. Methods Mol Biol (2007) 0.78
Cell senescence culturing methods. Methods Mol Biol (2013) 0.78
Retrovirus-mediated RNA interference. Targeting hTERT through stable expression of short-hairpin RNA. Methods Mol Biol (2007) 0.78
Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis. Epigenomics (2013) 0.77
Differential expression of epigenetic modulators during human embryonic stem cell differentiation. Mol Biotechnol (2008) 0.77
The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes. J Oncol (2011) 0.77
Methods of telomerase inhibition. Methods Mol Biol (2007) 0.76
A method to detect DNA methyltransferase I gene transcription in vitro in aging systems. Methods Mol Biol (2007) 0.76
Methylated-CpG Island Recovery Assay. Methods Mol Biol (2011) 0.76
Analysis of biomarkers of caloric restriction in aging cells. Methods Mol Biol (2013) 0.75
The transposon-driven evolutionary origin and basis of histone deacetylase functions and limitations in disease prevention. Clin Epigenetics (2011) 0.75