Chemokines: a new class of neuromodulator?

Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS One (2010) 3.24

Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacol Ther (2010) 1.62

The chemokine stromal cell-derived factor-1 regulates GABAergic inputs to neural progenitors in the postnatal dentate gyrus. J Neurosci (2008) 1.59

Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study. Mol Autism (2011) 1.51

Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury. Pain (2009) 1.48

Glia in pathological pain: a role for fractalkine. J Neuroimmunol (2008) 1.39

Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes. J Immunol (2008) 1.36

Involvement of TRPC channels in CCL2-mediated neuroprotection against tat toxicity. J Neurosci (2009) 1.34

New perspectives on central and peripheral immune responses to acute traumatic brain injury. J Neuroinflammation (2012) 1.34

HIV-1 neuroimmunity in the era of antiretroviral therapy. Neurobiol Dis (2010) 1.32

Chemokine action in the nervous system. J Neurosci (2008) 1.26

Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage. Open Biol (2013) 1.21

Production of proinflammatory cytokines and chemokines during neuroinflammation: novel roles for estrogen receptors alpha and beta. Endocrinology (2010) 1.17

Cytokines and brain excitability. Front Neuroendocrinol (2011) 1.11

Lipocalin-2 Is a chemokine inducer in the central nervous system: role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migration. J Biol Chem (2011) 1.10

Neuronal MCP-1 mediates microglia recruitment and neurodegeneration induced by the mild impairment of oxidative metabolism. Brain Pathol (2010) 1.06

Interactions between chemokines: regulation of fractalkine/CX3CL1 homeostasis by SDF/CXCL12 in cortical neurons. J Biol Chem (2010) 1.06

Minimal NF-κB activity in neurons. Neuroscience (2013) 1.04

Chemokine signaling in cancer: Implications on the tumor microenvironment and therapeutic targeting. Cancer Ther (2009) 1.03

Fractalkine (CX3CL1) enhances hippocampal N-methyl-D-aspartate receptor (NMDAR) function via D-serine and adenosine receptor type A2 (A2AR) activity. J Neuroinflammation (2013) 1.03

Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures. J Neuroinflammation (2010) 1.02

CX(3)CR1 deficiency alters hippocampal-dependent plasticity phenomena blunting the effects of enriched environment. Front Cell Neurosci (2011) 1.02

Maternal Infection During Pregnancy and Autism Spectrum Disorders. J Autism Dev Disord (2015) 1.00

Modulation of hippocampal stratum lacunosum-moleculare microcircuits. J Physiol (2010) 1.00

CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment. Front Cell Neurosci (2014) 0.96

HIV neuropathogenesis: a tight rope walk of innate immunity. J Neuroimmune Pharmacol (2010) 0.92

SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. Neuropharmacology (2009) 0.90

Cytokine involvement in stress may depend on corticotrophin releasing factor to sensitize ethanol withdrawal anxiety. Brain Behav Immun (2011) 0.90

Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation. PLoS One (2013) 0.89

Spinal interleukin-10 therapy to treat peripheral neuropathic pain. Neuromodulation (2012) 0.88

Systematic Review of the Neurobiological Relevance of Chemokines to Psychiatric Disorders. Front Cell Neurosci (2015) 0.88

Increased brain damage after ischaemic stroke in mice lacking the chemokine receptor CCR5. Br J Pharmacol (2010) 0.88

Neuroendocrine immunoregulation in multiple sclerosis. Clin Dev Immunol (2013) 0.87

Transcriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology. BMC Genomics (2012) 0.86

Fractalkine/CX3CL1 enhances GABA synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. Neuroscience (2009) 0.86

GABAergic activities enhance macrophage inflammatory protein-1alpha release from microglia (brain macrophages) in postnatal mouse brain. J Physiol (2008) 0.86

CCL5 and cytokine expression in the rat brain: differential modulation by chronic morphine and morphine withdrawal. Brain Behav Immun (2013) 0.85

Neuroimmune mechanisms of alcohol and drug addiction. Int Rev Neurobiol (2014) 0.84

Neonatal cytokines and chemokines and risk of Autism Spectrum Disorder: the Early Markers for Autism (EMA) study: a case-control study. J Neuroinflammation (2014) 0.84

Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery. Prog Neurobiol (2016) 0.83

CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension. PLoS One (2012) 0.83

The "window of susceptibility" for inflammation in the immature central nervous system is characterized by a leaky blood-brain barrier and the local expression of inflammatory chemokines. Neurobiol Dis (2009) 0.82

CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity. Front Cell Neurosci (2014) 0.81

Glial and Neuroimmune Mechanisms as Critical Modulators of Drug Use and Abuse. Neuropsychopharmacology (2016) 0.81

When human immunodeficiency virus meets chemokines and microglia: neuroprotection or neurodegeneration? J Neuroimmune Pharmacol (2012) 0.81

Disruption of neuronal CXCR4 function by opioids: preliminary evidence of ferritin heavy chain as a potential etiological agent in neuroAIDS. J Neuroimmunol (2010) 0.81

Autism spectrum disorder in children born preterm-role of exposure to perinatal inflammation. Front Neurosci (2013) 0.80

Expression of CXCL12 and CXCL14 during eye development in chick and mouse. Gene Expr Patterns (2013) 0.80

Adolescent intermittent ethanol exposure enhances ethanol activation of the nucleus accumbens while blunting the prefrontal cortex responses in adult rat. Neuroscience (2015) 0.80

Molecular mechanisms underlying hypothermia-induced neuroprotection. Stroke Res Treat (2010) 0.79

Twin disulfides for orthogonal disulfide pairing and the directed folding of multicyclic peptides. Nat Chem (2012) 0.78

Knockout of CXCR5 increases the population of immature neural cells and decreases proliferation in the hippocampal dentate gyrus. J Neuroinflammation (2014) 0.78

Functions of the chemokine receptor CXCR4 in the central nervous system and its regulation by μ-opioid receptors. Int Rev Neurobiol (2014) 0.78

Gray matter volumes in patients with chronic fatigue syndrome. Evid Based Complement Alternat Med (2015) 0.77

Evidence for TNFα action on excitatory and inhibitory neurotransmission in the central amygdala: a brain site influenced by stress. Brain Behav Immun (2013) 0.77

Effects of methylmercury contained in a diet mimicking the Wayana Amerindians contamination through fish consumption: mercury accumulation, metallothionein induction, gene expression variations, and role of the chemokine CCL2. Int J Mol Sci (2012) 0.77

Neuroimmunology and neuroepigenetics in the establishment of sex differences in the brain. Nat Rev Neurosci (2017) 0.76

The triplet puzzle theory indicates extensive formation of heteromers between opioid and chemokine receptor subtypes. J Neural Transm (Vienna) (2015) 0.76

Persistent adaptation by chronic alcohol is facilitated by neuroimmune activation linked to stress and CRF. Alcohol (2016) 0.76

Role of Atypical Chemokine Receptors in Microglial Activation and Polarization. Front Aging Neurosci (2017) 0.76

Glial Modulation by N-acylethanolamides in Brain Injury and Neurodegeneration. Front Aging Neurosci (2016) 0.75

Is there a role for monocyte chemoattractant protein-1 in delirium? Novel observations in elderly hip fracture patients. BMC Res Notes (2015) 0.75

The chemokine CXCL16 modulates neurotransmitter release in hippocampal CA1 area. Sci Rep (2016) 0.75

Negative neuroplasticity in chronic traumatic brain injury and implications for neurorehabilitation. Neuropsychol Rev (2014) 0.75

Central CCL2 signaling onto MCH neurons mediates metabolic and behavioral adaptation to inflammation. EMBO Rep (2016) 0.75

Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System. Int J Endocrinol (2014) 0.75

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia. Front Psychiatry (2017) 0.75

What are chemokine signalling systems doing in the brain? J Physiol (2010) 0.75

Systemic leukotriene B4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat. J Physiol (2016) 0.75

Neuroimmune pharmacology as an emerging curriculum for pre-medical students. J Neuroimmune Pharmacol (2010) 0.75

CCL5-Glutamate Cross-Talk in Astrocyte-Neuron Communication in Multiple Sclerosis. Front Immunol (2017) 0.75

The G Protein-Coupled Receptor UT of the Neuropeptide Urotensin II Displays Structural and Functional Chemokine Features. Front Endocrinol (Lausanne) (2017) 0.75

Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons. Eur J Neurosci (2002) 1.52

Spinal CCL2 pronociceptive action is no longer effective in CCR2 receptor antagonist-treated rats. J Neurochem (2008) 1.37

Highly regionalized neuronal expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) in rat brain: evidence for its colocalization with neurotransmitters and neuropeptides. J Comp Neurol (2005) 1.32

Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons. Eur J Neurosci (2003) 1.30

Constitutive neuronal expression of CCR2 chemokine receptor and its colocalization with neurotransmitters in normal rat brain: functional effect of MCP-1/CCL2 on calcium mobilization in primary cultured neurons. J Comp Neurol (2005) 1.30

The chemokine SDF-1 differentially regulates axonal elongation and branching in hippocampal neurons. J Cell Sci (2005) 1.26

Constitutive expression of CCR2 chemokine receptor and inhibition by MCP-1/CCL2 of GABA-induced currents in spinal cord neurones. J Neurochem (2005) 1.26

CCL2 released from neuronal synaptic vesicles in the spinal cord is a major mediator of local inflammation and pain after peripheral nerve injury. J Neurosci (2011) 1.17

Estradiol inhibits ongoing autoimmune neuroinflammation and NFkappaB-dependent CCL2 expression in reactive astrocytes. Proc Natl Acad Sci U S A (2010) 1.09

Altered processing of the neurotensin/neuromedin N precursor in PC2 knock down mice: a biochemical and immunohistochemical study. J Neurochem (2002) 1.08

Chemokines and chemokine receptors in the brain: implication in neuroendocrine regulation. J Mol Endocrinol (2007) 1.04

Constitutive activation of the neurotensin receptor 1 by mutation of Phe(358) in Helix seven. Br J Pharmacol (2002) 0.99

The chemokine SDF-1/CXCL12 modulates the firing pattern of vasopressin neurons and counteracts induced vasopressin release through CXCR4. Proc Natl Acad Sci U S A (2006) 0.97

Chemokines and brain functions. Curr Drug Targets Inflamm Allergy (2005) 0.94

Cellular and subcellular localization of CXCL12 and CXCR4 in rat nociceptive structures: physiological relevance. Eur J Neurosci (2012) 0.93

Dendrite-selective redistribution of the chemokine receptor CXCR4 following agonist stimulation. Mol Cell Neurosci (2006) 0.84

NOV/CCN3 attenuates inflammatory pain through regulation of matrix metalloproteinases-2 and -9. J Neuroinflammation (2012) 0.84

The Arg617-Arg618 cleavage site in the C-terminal domain of PC1 plays a major role in the processing and targeting of the enzyme within the regulated secretory pathway. J Neurochem (2003) 0.79

Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity. Biochem Biophys Res Commun (2002) 0.79

[Chemokines as new actors in the dopaminergic system]. Biol Aujourdhui (2011) 0.79

Cellular and subcellular evidence for neuronal interaction between the chemokine stromal cell-derived factor-1/CXCL 12 and vasopressin: regulation in the hypothalamo-neurohypophysial system of the Brattleboro rats. Endocrinology (2007) 0.77

Insertion of dibasic residues directs a constitutive protein to the regulated secretory pathway. Biochem Biophys Res Commun (2002) 0.77

Implication of CCR2 chemokine receptor in cocaine-induced sensitization. J Mol Neurosci (2011) 0.77