Published in Nat Chem on October 28, 2012
In vitro and cellular self-assembly of a Zn-binding protein cryptand via templated disulfide bonds. J Am Chem Soc (2013) 0.86
The cyclic cystine ladder in θ-defensins is important for structure and stability, but not antibacterial activity. J Biol Chem (2013) 0.82
Bioreducible polycations as shuttles for therapeutic nucleic acid and protein transfection. Antioxid Redox Signal (2014) 0.76
ExPASy: The proteomics server for in-depth protein knowledge and analysis. Nucleic Acids Res (2003) 17.39
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix. Science (2004) 7.63
Formation and transfer of disulphide bonds in living cells. Nat Rev Mol Cell Biol (2002) 3.12
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3. Proc Natl Acad Sci U S A (2003) 2.32
Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. J Mol Biol (1999) 2.29
Contemporary strategies for peptide macrocyclization. Nat Chem (2011) 2.23
Chemokines: a new class of neuromodulator? Nat Rev Neurosci (2007) 1.76
Phage-encoded combinatorial chemical libraries based on bicyclic peptides. Nat Chem Biol (2009) 1.67
Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjug Chem (2001) 1.67
Controlled folding of synthetic polymer chains through the formation of positionable covalent bridges. Nat Chem (2011) 1.62
The engineering of an orally active conotoxin for the treatment of neuropathic pain. Angew Chem Int Ed Engl (2010) 1.54
Disulfide-linked protein folding pathways. Annu Rev Cell Dev Biol (2008) 1.40
Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment. Angew Chem Int Ed Engl (2012) 1.24
Recent progress of the synthetic studies of biologically active marine cyclic peptides and depsipeptides. Chem Rev (2005) 1.19
Direct observation of disulfide isomerization in a single protein. Nat Chem (2011) 1.17
The CXC motif: a functional mimic of protein disulfide isomerase. Biochemistry (2003) 1.02
Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries. Angew Chem Int Ed Engl (2003) 0.97
Cyclotides as a basis for drug design. Expert Opin Drug Discov (2012) 0.97
Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif . Biochemistry (2009) 0.97
Dynamic peptides as biomimetic carbohydrate receptors. Angew Chem Int Ed Engl (2010) 0.96
Chemical synthesis, folding, and structural insights into O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor. J Am Chem Soc (2010) 0.95
Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductase. Chem Rev (2011) 0.86
Interplay of chemical microenvironment and redox environment on thiol-disulfide exchange kinetics. Chemistry (2011) 0.81
A facile route to dynamic glycopeptide libraries based on disulfide-linked sugar-peptide coupling. Bioorg Med Chem Lett (2004) 0.77
Kinetics of disulfide exchange reactions of monomer and dimer loops of cysteine-valine-cysteine peptides. Biochemistry (1988) 0.77
Block copolymer micelles: preparation, characterization and application in drug delivery. J Control Release (2005) 2.79
In situ-forming hydrogels--review of temperature-sensitive systems. Eur J Pharm Biopharm (2004) 2.08
Quantitative imaging of lymphatic function with liposomal indocyanine green. Cancer Res (2010) 1.43
The journey of a drug-carrier in the body: an anatomo-physiological perspective. J Control Release (2011) 1.32
Polyester-based micelles and nanoparticles for the parenteral delivery of taxanes. J Control Release (2009) 1.31
Organogels and their use in drug delivery--a review. J Control Release (2007) 1.30
A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel. Eur J Pharm Biopharm (2004) 1.23
Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis. Biomaterials (2013) 1.22
Membrane-destabilizing polyanions: interaction with lipid bilayers and endosomal escape of biomacromolecules. Adv Drug Deliv Rev (2004) 1.20
Polymeric binders suppress gliadin-induced toxicity in the intestinal epithelium. Gastroenterology (2008) 1.12
Stereocomplex block copolymer micelles: core-shell nanostructures with enhanced stability. Nano Lett (2005) 1.08
pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates. Adv Drug Deliv Rev (2011) 1.06
Toxicity of silver nanoparticles in macrophages. Small (2013) 1.05
Co-encapsulation of magnetic nanoparticles and doxorubicin into biodegradable microcarriers for deep tissue targeting by vascular MRI navigation. Biomaterials (2011) 1.04
The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues. Gastroenterology (2011) 1.03
Polymeric micelles for oral drug delivery. Eur J Pharm Biopharm (2010) 1.02
Dynamics of lymphatic regeneration and flow patterns after lymph node dissection. Breast Cancer Res Treat (2013) 1.01
Characterization of the membrane-destabilizing properties of different pH-sensitive methacrylic acid copolymers. Biochim Biophys Acta (2003) 1.01
Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab' fragments. Biomaterials (2007) 1.00
Magnetic nanoparticles encapsulated into biodegradable microparticles steered with an upgraded magnetic resonance imaging system for tumor chemoembolization. Biomaterials (2009) 0.99
Biomedical applications of bisphosphonates. J Control Release (2013) 0.98
Biocompatibility of thermosensitive chitosan-based hydrogels: an in vivo experimental approach to injectable biomaterials. Biomaterials (2002) 0.98
Long circulating poly(ethylene glycol)-decorated lipid nanocapsules deliver docetaxel to solid tumors. Pharm Res (2006) 0.98
Solubilization of docetaxel in poly(ethylene oxide)-block-poly(butylene/styrene oxide) micelles. Biomacromolecules (2007) 0.97
Effect of poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as coating agent on the opsonization, phagocytosis, and pharmacokinetics of biodegradable nanoparticles. Biomacromolecules (2009) 0.96
pH-responsive polymeric micelles of poly(ethylene glycol)-b-poly(alkyl(meth)acrylate-co-methacrylic acid): influence of the copolymer composition on self-assembling properties and release of candesartan cilexetil. Eur J Pharm Biopharm (2006) 0.96
Treatment of calcium channel blocker-induced cardiovascular toxicity with drug scavenging liposomes. Biomaterials (2012) 0.94
A novel one-step drug-loading procedure for water-soluble amphiphilic nanocarriers. Pharm Res (2004) 0.93
Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates. Nat Chem (2013) 0.93
In vivo fluorescence imaging of exogenous enzyme activity in the gastrointestinal tract. Proc Natl Acad Sci U S A (2011) 0.92
Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease. Biomaterials (2010) 0.92
In situ-forming oleogel implant for rivastigmine delivery. Pharm Res (2007) 0.91
Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice. Cancer Res (2012) 0.90
Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization. J Control Release (2004) 0.90
Brain targeting using novel lipid nanovectors. J Control Release (2007) 0.90
Enhancement of docetaxel solubility via conjugation of formulation-compatible moieties. Org Biomol Chem (2009) 0.89
Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes. J Control Release (2004) 0.89
Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo. Angiogenesis (2013) 0.89
Targeting bacterial toxins. Angew Chem Int Ed Engl (2012) 0.88
Nanonization of megestrol acetate by laser fragmentation in aqueous milieu. J Control Release (2010) 0.88
New pharmaceutical applications for macromolecular binders. J Control Release (2011) 0.88
Gene delivery with bisphosphonate-stabilized calcium phosphate nanoparticles. J Control Release (2010) 0.87
Targeting of injectable drug nanocrystals. Mol Pharm (2014) 0.87
Long-circulating poly(ethylene glycol)-coated emulsions to target solid tumors. Eur J Pharm Biopharm (2007) 0.87
Transmembrane pH-gradient liposomes to treat cardiovascular drug intoxication. ACS Nano (2010) 0.87
Pharmacokinetics and biodistribution of N-isopropylacrylamide copolymers for the design of pH-sensitive liposomes. Biomaterials (2009) 0.87
Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs. Int J Pharm (2002) 0.87
Novel long-circulating lipid nanocapsules. Pharm Res (2004) 0.86
In vivo evaluation of pH-sensitive polymer-based immunoliposomes targeting the CD33 antigen. Mol Pharm (2010) 0.86
Tracking the bioreduction of disulfide-containing cationic dendrimers. Angew Chem Int Ed Engl (2012) 0.86
Fabrication of paclitaxel nanocrystals by femtosecond laser ablation and fragmentation. J Pharm Sci (2010) 0.86
In situ-forming pharmaceutical organogels based on the self-assembly of L-alanine derivatives. Pharm Res (2004) 0.86
PEG nanocages as non-sheddable stabilizers for drug nanocrystals. ACS Nano (2012) 0.86
Predicting the solubility of the anti-cancer agent docetaxel in small molecule excipients using computational methods. Pharm Res (2007) 0.86
Reverse polymeric micelles for pharmaceutical applications. J Control Release (2008) 0.85
pH-sensitive unimolecular polymeric micelles: synthesis of a novel drug carrier. Bioconjug Chem (2003) 0.85
pH-sensitive immunoliposomes specific to the CD33 cell surface antigen of leukemic cells. Int J Pharm (2009) 0.84
Characterization of polyion complex micelles designed to address the challenges of oligonucleotide delivery. Pharm Res (2008) 0.84
Preparation and tumor cell uptake of poly(N-isopropylacrylamide) folate conjugates. Bioconjug Chem (2002) 0.83
Prevention measures and exploratory pharmacological treatments of celiac disease. Am J Gastroenterol (2010) 0.83
First report on the efficacy of l-alanine-based in situ-forming implants for the long-term parenteral delivery of drugs. J Control Release (2005) 0.83
On the characterization of pH-sensitive liposome/polymer complexes. Biomacromolecules (2003) 0.83
Long circulating lipid nanocapsules for drug detoxification. Biomaterials (2007) 0.83
Aminated linear and star-shape poly(glycerol methacrylate)s: synthesis and self-assembling properties. Biomacromolecules (2010) 0.83
Thiol-functionalized polymeric micelles: from molecular recognition to improved mucoadhesion. Bioconjug Chem (2005) 0.82
siRNA nanocarriers based on methacrylic acid copolymers. J Control Release (2010) 0.82
Interaction of alpha-gliadin with poly(HEMA-co-SS): structural characterization and biological implication. Biopolymers (2009) 0.81
On the role of methacrylic acid copolymers in the intracellular delivery of antisense oligonucleotides. Eur J Pharm Biopharm (2005) 0.81
The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity. Biomaterials (2012) 0.81
Preparation and in vivo evaluation of PEGylated spherulite formulations. Biochim Biophys Acta (2005) 0.81
Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery. J Control Release (2013) 0.81
Influence of physical parameters and lubricants on the compaction properties of granulated and non-granulated cross-linked high amylose starch. Chem Pharm Bull (Tokyo) (2002) 0.81
Characterization and biocompatibility of organogels based on L-alanine for parenteral drug delivery implants. Biomaterials (2005) 0.81
Interplay of chemical microenvironment and redox environment on thiol-disulfide exchange kinetics. Chemistry (2011) 0.81
Broad control of disulfide stability through microenvironmental effects and analysis in complex redox environments. Biomacromolecules (2013) 0.80
Steric stabilization of liposomes by pH-responsive N-isopropylacrylamide copolymer. J Pharm Sci (2002) 0.80
Celiac disease: a challenging disease for pharmaceutical scientists. Pharm Res (2012) 0.80
Rescue of amitriptyline-intoxicated hearts with nanosized vesicles. Cardiovasc Res (2007) 0.80
Interaction of alpha-gliadin with polyanions: design considerations for sequestrants used in supportive treatment of celiac disease. Biopolymers (2010) 0.79
Poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as polymeric emulsifier for the preparation of biodegradable nanoparticles. J Pharm Sci (2007) 0.79
Self-assembled nanocages for hydrophilic guest molecules. J Am Chem Soc (2006) 0.79
Adherence to cholinesterase inhibitors in patients with Alzheimer's disease. J Am Geriatr Soc (2009) 0.79
Enhancement of oral bioavailability of poorly water-soluble drugs by poly(ethylene glycol)-block-poly(alkyl acrylate-co-methacrylic acid) self-assemblies. J Control Release (2005) 0.79
Study of the micellization behavior of different order amino block copolymers with heparin. Pharm Res (2004) 0.79
Is there a future for cell-penetrating peptides in oligonucleotide delivery? Eur J Pharm Biopharm (2013) 0.79
Irradiating or autoclaving chitosan/polyol solutions: effect on thermogelling chitosan-beta-glycerophosphate systems. Chem Pharm Bull (Tokyo) (2002) 0.79
Report on the use of poly(organophosphazenes) for the design of stimuli-responsive vesicles. Biomacromolecules (2004) 0.79
siRNA transfection with calcium phosphate nanoparticles stabilized with PEGylated chelators. Adv Healthc Mater (2012) 0.78
pH-Responsive molecular tweezers. J Am Chem Soc (2010) 0.78
Development and physico-chemical characterization of a liposomal formulation of istaroxime. Eur J Pharm Biopharm (2011) 0.78
Bio-reduction of redox-sensitive albumin conjugates in FcRn-expressing cells. Angew Chem Int Ed Engl (2014) 0.78
Preparation of polyion complex micelles from poly(ethylene glycol)-block-polyions. J Control Release (2011) 0.78