The detection of the genetic carriers of hereditary disease.

Sequential tests for the detection of linkage. Am J Hum Genet (1955) 43.74

Our load of mutations. Am J Hum Genet (1950) 24.01

The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type. Am J Hum Genet (1956) 8.34

A genetic study of multiple polyposis of the colon with an appendix deriving a method of estimating relative fitness. Am J Hum Genet (1955) 3.64

The laboratory detection of heterozygotes. Am J Hum Genet (1957) 1.58

Our twenty-fifth. Am J Hum Genet (1974) 1.53

Elimination of recessive lethals from the population when the heterozygote can be detected. Am J Hum Genet (1953) 1.07

PROBLEMS confronting human geneticists. Am J Hum Genet (1954) 0.97

The satellited chromosomes of man with reference to the marfan syndrome. Am J Hum Genet (1963) 0.88

On some pitfalls in developing an adequate genetic hypothesis. Am J Hum Genet (1955) 0.85

In the beginning... Am J Hum Genet (2000) 0.79

The utility of simplex sibships in the characterization of HLA-linked disease susceptibility genes. Am J Hum Genet (1984) 0.75

SERUM URATE IN RELATIVES OF GOUTY PATIENTS. J Clin Invest (1940) 8.27

Further Studies on the Genetics of Thalassemia. Genetics (1947) 8.04

THE GENETICS OF GOUT AND HYPERURICEMIA-AN ANALYSIS OF NINETEEN FAMILIES. J Clin Invest (1948) 5.13

Oval Blood Cells in Human Subjects Tested for Linkage with Taste for Ptc, Mid-Digital Hair, Hair Color, a-B Agglutinogens, and Sex. Genetics (1941) 2.99

Linkage Between the Genes for Sickle Cells and the M-N Blood Types. Science (1947) 2.98

Sex Linkage in Man. Genetics (1930) 2.90

Autosomal Linkage in Man-The Recombination Ratio between Congenital Tooth Deficiency and Hair Color. Proc Natl Acad Sci U S A (1938) 2.46

PALM PATTERNS AND HANDEDNESS. Science (1941) 2.39

Asian affinities and continental radiation of the four founding Native American mtDNAs. Am J Hum Genet (1993) 6.81

The incidence of consanguineous matings in Japan, with remarks on the estimation of comparative gene frequencies and the expected rate of appearance of induced recessive mutations. Am J Hum Genet (1949) 5.72

The Inheritance of Sickle Cell Anemia. Science (1949) 5.26

The genetic structure of a tirbal population, the Vanomama Indians. II. Eleven blood-group systems and the ABH-Le secretor traits. Ann Hum Genet (1972) 4.87

The costs of human inbreeding and their implications for variations at the DNA level. Nat Genet (1994) 3.69

The genetic structure of a tribal population, the Yanomama Indians. XII. Biodemographic studies. Am J Phys Anthropol (1975) 3.40

Indirect estimates of mutation rates in tribal Amerindians. Proc Natl Acad Sci U S A (1978) 3.36

Regional linguistic and genetic differences among Yanomama indians. Science (1974) 2.87

Mitochondrial DNA "clock" for the Amerinds and its implications for timing their entry into North America. Proc Natl Acad Sci U S A (1994) 2.86

The NAS-NRC twin panel: methods of construction of the panel, zygosity diagnosis, and proposed use. Am J Hum Genet (1967) 2.81

"Private" genetic variants and the frequency of mutation among South American Indians. Proc Natl Acad Sci U S A (1973) 2.64

The influence of cultural factors on the demography and pattern of gene flow from the Makiritare to the Yanomama Indians. Am J Phys Anthropol (1970) 2.59

Congenital Aniridia. Am J Hum Genet (1960) 2.50

Children of incest. Pediatrics (1967) 2.32

Probability of founder effect in a tribal population. Proc Natl Acad Sci U S A (1978) 2.29

The genetic structure of a tribal population, the Yanomama Indians XI. Gene frequencies for 10 blood groups and the ABH-Le secretor traits in the Yanomama and their neighbors; the uniqueness of the tribe. Am J Hum Genet (1975) 2.28

Genetic effects of the atomic bombs: a reappraisal. Science (1981) 2.27

The genetic structure of a tribal population, the Yanomama Indians. XV. Patterns inferred by autocorrelation analysis. Genetics (1986) 2.18

Blood pressure, sodium intake, and sodium related hormones in the Yanomamo Indians, a "no-salt" culture. Circulation (1975) 2.17

Allelic disequilibrium and allele frequency distribution as a function of social and demographic history. Am J Hum Genet (1997) 2.14

Population amalgamation and genetic variation: observations on artificially agglomerated tribal populations of Central and South America. Am J Hum Genet (1988) 2.13

JC virus DNA is present in the mucosa of the human colon and in colorectal cancers. Proc Natl Acad Sci U S A (1999) 2.08

Founder effect and number of private polymorphisms observed in Amerindian tribes. Proc Natl Acad Sci U S A (1978) 2.06

Description and validation of a method for simultaneous estimation of effective population size and mutation rate from human population data. Proc Natl Acad Sci U S A (1989) 2.02

Lessons from a "primitive" people. Science (1970) 2.01

Rare variants, private polymorphisms, and locus heterozygosity in Amerindian populations. Am J Hum Genet (1978) 1.96

I. Demographic data on two additional villages: Genetic structure of the tribe. Am J Hum Genet (1967) 1.95

Multiple-locus departures from panmictic equilibrium within and between village gene pools of Amerindian tribes at different stages of agglomeration. Genetics (1983) 1.93

Village and tribal genetic distances among American Indians, and the possible implications for human evolution. Proc Natl Acad Sci U S A (1970) 1.92

The detection of increased mutation rates in human populations. Perspect Biol Med (1971) 1.91

Microevolution in lower Central America: genetic characterization of the Chibcha-speaking groups of Costa Rica and Panama, and a consensus taxonomy based on genetic and linguistic affinity. Am J Hum Genet (1990) 1.86

The rate with which spontaneous mutation alters the electrophoretic mobility of polypeptides. Proc Natl Acad Sci U S A (1986) 1.85

Search for mutations affecting protein structure in children of atomic bomb survivors: preliminary report. Proc Natl Acad Sci U S A (1980) 1.80

The blood groups and secretor types in five potentially fatal diseases of Caucasian children. Acta Genet Stat Med (1965) 1.78

Gene frequencies and microdifferentiation among the Makiritare Indians. IV. A comparison of a genetic network with ethnohistory and migration matrices; a new index of genetic isolation. Am J Hum Genet (1970) 1.78

The phylogenic relationships of some Indian tribes of Central and South America. Am J Hum Genet (1969) 1.77

Gene frequencies and microdifferentiation among the Makiritare Indians. I. Eleven blood group systems and the ABH-Le secretor traits: a note on Rh gene frequency determinations. Am J Hum Genet (1970) 1.72

Microevolution of the Chibcha-speaking peoples of lower Central America: rare genes in an Amerindian complex. Am J Hum Genet (1992) 1.61

Malignant tumors during the first 2 decades of life in the offspring of atomic bomb survivors. Am J Hum Genet (1990) 1.59

The genetic structure of a tribal population, the Yanomama Indians. IX. Gene frequencies for 18 serum protein and erythrocyte enzyme systems in the Yanomama and five neighboring tribes: nine new variants. Am J Hum Genet (1973) 1.59

Multivariate analysis of gametic disequilibrium in the Yanomama. Genetics (1977) 1.57

Further studies on the Xavante Indians. X. Some hypotheses-generalizations resulting from these studies. Am J Hum Genet (1967) 1.55

Our twenty-fifth. Am J Hum Genet (1974) 1.53

Mortality in the children of atomic bomb survivors and controls. Genetics (1974) 1.51

Some further observations on the sex ratio among infants born to survivors of the atomic bombings of Hiroshima and Nagasaki. Am J Hum Genet (1966) 1.51

Developments in monitoring human populations for mutation rates. Mutat Res (1974) 1.50

The effects of parental consanguinity and inbreeding in Hirado, Japan. V. Summary and interpretation. Am J Hum Genet (1972) 1.50

Genetic studies on the Ticuna, an enigmatic tribe of Central Amazonas. Ann Hum Genet (1980) 1.49

Rate of spontaneous mutation at human loci encoding protein structure. Proc Natl Acad Sci U S A (1980) 1.49

Notes on the effect of measles and measles vaccine in a virgin-soil population of South American Indians. Am J Epidemiol (1970) 1.47

Studies on genetic selection in a completely ascertained caucasian population. II. Family analyses of 11 blood group systems. Am J Hum Genet (1971) 1.46

Studies on genetic selection in a completely ascertained caucasian population. I. Frequencies, age and sex effects, and phenotype associations for 12 blood group systems. Am J Hum Genet (1971) 1.44

The population structure of an Amerindian tribe, the Yanomama. Annu Rev Genet (1978) 1.42

Genetic studies of the Macushi and Wapishana Indians. I. Rare genetic variants and a "private polymorphism' of esterase A. Hum Genet (1977) 1.41

Human serum albumin: twenty-three genetic variants and their population distribution. Ann Hum Genet (1973) 1.40

Further studies on the Xavante Indians. 3. Blood groups and ABH-Lea secretor types in the Simões Lopes and São Marcos Xavantes. Am J Hum Genet (1967) 1.39

Gene frequencies and microdifferentiation among the Makiritare Indians. II. Seven serum protein systems. Am J Hum Genet (1970) 1.39

The genetic structure of a tribal population, the Yanomama Indians. 3. Seven serum protein systems. Ann Hum Genet (1972) 1.36

Amino acid substitutions in inherited albumin variants from Amerindian and Japanese populations. Proc Natl Acad Sci U S A (1987) 1.35

Additional data on the population distribution of human serum albumin genes; three new variants. Ann Hum Genet (1973) 1.35

Migration and genetic infrastructure of the Central American Guaymi and their affinities with other tribal groups. Am J Phys Anthropol (1982) 1.35

Serum proteins, hemoglobins and erythrocyte enzymes of Brazilian Cayapo Indians. Hum Biol (1972) 1.31

The frequency in Japanese of genetic variants of 22 proteins. V. Summary and comparison with data on Caucasians from the British Isles. Ann Hum Genet (1978) 1.28

Intra and intertribal genetic variation within a linguistic group: the Ge-speaking indians of Brazil. Am J Phys Anthropol (1977) 1.27

A cohort-type study of survival in the children of parents exposed to atomic bombings. Am J Hum Genet (1966) 1.27

The genetic structure of a tribal population, the Yanomama Indians. XIV. Clines and their interpretation. Genetics (1976) 1.26

Congenital malformations, stillbirths, and early mortality among the children of atomic bomb survivors: a reanalysis. Radiat Res (1990) 1.26

Demographic structure of a primitive population: a simulation. Am J Phys Anthropol (1971) 1.23

Endemic human T cell lymphotropic virus type II infection among isolated Brazilian Amerindians. J Infect Dis (1992) 1.22

The demography of two tribes of primitive, relatively unacculturated American Indians. Proc Natl Acad Sci U S A (1968) 1.21

Mutation and disease in man. Can J Genet Cytol (1978) 1.20

The genetic structure of a tribal population, the Yanomama Indians. VI. Analysis by F-statistics (including a comparison with the Makiritare and Xavante). Genetics (1972) 1.20

Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? 1962. Bull World Health Organ (1999) 1.19

Two-dimensional electrophoresis of plasma polypeptides reveals "high" heterozygosity indices. Proc Natl Acad Sci U S A (1983) 1.18

The frequency in Japanese of genetic variants of 22 proteins. I. Albumin, ceruloplasmin, haptoglobin, and transferrin. Ann Hum Genet (1977) 1.17

Private polymorphisms: how many? How old? How useful for genetic taxonomies? Mol Phylogenet Evol (1996) 1.16

Two more "private" polymorphisms of Amerindian tribes: LDHb GUA-1 and ACP1 B GUA-1 in the Guaymi in Panama. Am J Hum Genet (1977) 1.15

The genetic structure of a tribal population, the Yanomama Indians. 1. Introduction. Ann Hum Genet (1972) 1.14

On some trends in understanding the genetics of man. Perspect Biol Med (1968) 1.13

The genetic structure of a tribal population, the Yanomama Indians. IV. Eleven erythrocyte enzymes and summary of protein variants. Ann Hum Genet (1972) 1.11

Epidemiologic studies among Amerindian populations of Amazônia. I. Pyoderma: prevalence and associated pathogens. Am J Trop Med Hyg (1979) 1.10

Gene frequencies and microdifferentiation among the Makiritare Indians. 3. Nine erythrocyte enzyme systems. Am J Hum Genet (1970) 1.09

Genetic studies of the Macushi and Wapishana Indians. II. Data on 12 genetic polymorphisms of the red cell and serum proteins: gene flor between the tribes. Hum Genet (1977) 1.08

Familial factors in early deaths: twins followed 30 years to ages 51-61 in 1978. Hum Genet (1981) 1.08

A phylogeny for the principal alleles of the human phosphoglucomutase-1 locus. Proc Natl Acad Sci U S A (1982) 1.08

Inbreeding estimation from population data: models, procedures and implications. Genetics (1977) 1.08

The frequency in Japanese of genetic variants of 22 proteins II. Carbonic anhydrase I and II, lactate dehydrogenase, malate dehydrogenase, nucleoside phosphorylase, triose phosphate isomerase, haemoglobin A and haemoglobin A2. Ann Hum Genet (1977) 1.08

Mortality among the offspring (F1) of atomic bomb survivors, 1946-85. J Radiat Res (1991) 1.08

The genetic structure of a tribal population, the Yanomama indians. VII. Anthropometric differences among Yanomama villages. Am J Phys Anthropol (1972) 1.08

The impact of random and lineal fission of the genetic divergence of small human groups: a case study among the Yanomama. Genetics (1981) 1.07

The frequency in Japanese of genetic variants of 22 proteins. III. Phosphoglucomutase-1, phosphoglucomutase-2, 6-phosphogluconate dehydrogenase, adenylate kinase, and adenosine deaminase. Ann Hum Genet (1977) 1.06

Chromosomal breakage in leukocytes of South American Indians. Cytogenet Cell Genet (1973) 1.04

Separation of allelic variants by two-dimensional electrophoresis. Am J Hum Genet (1982) 1.03

The frequency among Japanese of heterozygotes for deficiency variants of 11 enzymes. Am J Hum Genet (1983) 1.03

Electrophoretic variants in three Amerindian tribes: the Baniwa, Kanamari, and Central Pano of western Brazil. Am J Phys Anthropol (1979) 1.03

The genetic structure of a tribal population, the Yanomama Indians. X. Agreement between representations of village distances based on different sets of characteristics. Am J Hum Genet (1974) 1.03

Polydactyly of the Second Metatarsal with Associated Defects of the Feet: A New, Simply Inherited Skeletal Deformity. Am J Hum Genet (1963) 1.02

The effects of parental consanguinity and inbreeding in Hirado, Japan. II. Physical development, tapping rate, blood pressure, intelligence quotient, and school performance. Am J Hum Genet (1970) 1.01

The immunoglobulin allotypes (Gm and Km) of twelve Indian tribes of Central and South America. Am J Phys Anthropol (1978) 1.01