Published in J Theor Biol on September 12, 2007
Exploring the roles of noise in the eukaryotic cell cycle. Proc Natl Acad Sci U S A (2009) 1.46
Stochastic exit from mitosis in budding yeast: model predictions and experimental observations. Cell Cycle (2011) 1.46
A model of yeast cell-cycle regulation based on multisite phosphorylation. Mol Syst Biol (2010) 1.33
Robustness in glyoxylate bypass regulation. PLoS Comput Biol (2009) 1.15
Spatial cycles in G-protein crowd control. EMBO J (2010) 0.96
Large-scale analysis of network bistability for human cancers. PLoS Comput Biol (2010) 0.95
Mathematical model of the Drosophila circadian clock: loop regulation and transcriptional integration. Biophys J (2009) 0.93
Identifying functional mechanisms of gene and protein regulatory networks in response to a broader range of environmental stresses. Comp Funct Genomics (2010) 0.90
The Goldbeter-Koshland switch in the first-order region and its response to dynamic disorder. PLoS One (2008) 0.90
Emergence of switch-like behavior in a large family of simple biochemical networks. PLoS Comput Biol (2011) 0.89
Hybrid modeling and simulation of stochastic effects on progression through the eukaryotic cell cycle. J Chem Phys (2012) 0.85
Steady state detection of chemical reaction networks using a simplified analytical method. PLoS One (2010) 0.84
The capacity for multistability in small gene regulatory networks. BMC Syst Biol (2009) 0.84
Evolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human. PLoS One (2012) 0.81
The coupling of pathways and processes through shared components. BMC Syst Biol (2011) 0.80
A Model of Yeast Cell-Cycle Regulation Based on a Standard Component Modeling Strategy for Protein Regulatory Networks. PLoS One (2016) 0.78
Multi-Compartmentalisation in the MAPK Signalling Pathway Contributes to the Emergence of Oscillatory Behaviour and to Ultrasensitivity. PLoS One (2016) 0.77
Measurement and modeling of transcriptional noise in the cell cycle regulatory network. Cell Cycle (2013) 0.77
Snazer: the simulations and networks analyzer. BMC Syst Biol (2010) 0.77
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr Opin Cell Biol (2003) 8.91
Integrative analysis of cell cycle control in budding yeast. Mol Biol Cell (2004) 4.77
Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts. Proc Natl Acad Sci U S A (2002) 4.58
Design principles of biochemical oscillators. Nat Rev Mol Cell Biol (2008) 4.55
Steady states and oscillations in the p53/Mdm2 network. Cell Cycle (2005) 2.45
In vitro FRAP identifies the minimal requirements for Mad2 kinetochore dynamics. Curr Biol (2006) 2.37
Downregulation of PP2A(Cdc55) phosphatase by separase initiates mitotic exit in budding yeast. Cell (2006) 2.29
The dynamics of cell cycle regulation. Bioessays (2002) 2.21
Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex. Nat Cell Biol (2006) 1.92
A model for restriction point control of the mammalian cell cycle. J Theor Biol (2004) 1.86
Analysis of a generic model of eukaryotic cell-cycle regulation. Biophys J (2006) 1.86
Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint. Curr Biol (2009) 1.76
Irreversible cell-cycle transitions are due to systems-level feedback. Nat Cell Biol (2007) 1.68
Temporal organization of the cell cycle. Curr Biol (2008) 1.63
Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction. EMBO J (2011) 1.62
Endocytosis and signaling: cell logistics shape the eukaryotic cell plan. Physiol Rev (2012) 1.61
Modeling networks of coupled enzymatic reactions using the total quasi-steady state approximation. PLoS Comput Biol (2007) 1.58
Mathematical modeling as a tool for investigating cell cycle control networks. Methods (2007) 1.55
Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling. Elife (2013) 1.52
Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate. Cancer Res (2012) 1.47
Exploring the roles of noise in the eukaryotic cell cycle. Proc Natl Acad Sci U S A (2009) 1.46
Stochastic exit from mitosis in budding yeast: model predictions and experimental observations. Cell Cycle (2011) 1.46
Mathematical model of the cell division cycle of fission yeast. Chaos (2001) 1.44
The influence of catalysis on mad2 activation dynamics. PLoS Biol (2009) 1.40
Morphogenetic checkpoint in fission yeast? Yes! Microbiology (2002) 1.39
Bifurcation analysis of a model of the budding yeast cell cycle. Chaos (2004) 1.38
Exploring mechanisms of the DNA-damage response: p53 pulses and their possible relevance to apoptosis. Cell Cycle (2007) 1.37
A model of yeast cell-cycle regulation based on multisite phosphorylation. Mol Syst Biol (2010) 1.33
Mathematical model of the morphogenesis checkpoint in budding yeast. J Cell Biol (2003) 1.33
Switches and latches: a biochemical tug-of-war between the kinases and phosphatases that control mitosis. Philos Trans R Soc Lond B Biol Sci (2011) 1.30
Bistability by multiple phosphorylation of regulatory proteins. Prog Biophys Mol Biol (2009) 1.28
The JigCell model builder: a spreadsheet interface for creating biochemical reaction network models. IEEE/ACM Trans Comput Biol Bioinform (2006) 1.25
The BEG (PP2A-B55/ENSA/Greatwall) pathway ensures cytokinesis follows chromosome separation. Mol Cell (2013) 1.23
Control of cell proliferation, organ growth, and DNA damage response operate independently of dephosphorylation of the Arabidopsis Cdk1 homolog CDKA;1. Plant Cell (2009) 1.19
Another turn for p53. Mol Syst Biol (2006) 1.19
Low duplicability and network fragility of cancer genes. Trends Genet (2008) 1.18
A mathematical model for the reciprocal differentiation of T helper 17 cells and induced regulatory T cells. PLoS Comput Biol (2011) 1.18
the JigCell model builder and run manager. Bioinformatics (2004) 1.17
Dynamical modeling of syncytial mitotic cycles in Drosophila embryos. Mol Syst Biol (2007) 1.14
A quantitative study of the division cycle of Caulobacter crescentus stalked cells. PLoS Comput Biol (2007) 1.13
Threshold-controlled ubiquitination of the EGFR directs receptor fate. EMBO J (2013) 1.11
A proposal for robust temperature compensation of circadian rhythms. Proc Natl Acad Sci U S A (2007) 1.11
Computational analysis of dynamical responses to the intrinsic pathway of programmed cell death. Biophys J (2009) 1.11
Stochastic simulation of enzyme-catalyzed reactions with disparate timescales. Biophys J (2008) 1.10
Size control in growing yeast and mammalian cells. Theor Biol Med Model (2004) 1.05
Parameter estimation for a mathematical model of the cell cycle in frog eggs. J Comput Biol (2005) 1.04
System-level feedbacks make the anaphase switch irreversible. Proc Natl Acad Sci U S A (2011) 1.03
Temporal controls of the asymmetric cell division cycle in Caulobacter crescentus. PLoS Comput Biol (2009) 1.03
Modelling the fission yeast cell cycle. Brief Funct Genomic Proteomic (2004) 1.02
Cell cycle regulation by feed-forward loops coupling transcription and phosphorylation. Mol Syst Biol (2009) 1.01
Modeling the septation initiation network (SIN) in fission yeast cells. Curr Genet (2007) 1.01
A general G1/S-phase cell-cycle control module in the flowering plant Arabidopsis thaliana. PLoS Genet (2012) 1.01
Network topologies and dynamics leading to endotoxin tolerance and priming in innate immune cells. PLoS Comput Biol (2012) 1.00
Modular logical modelling of the budding yeast cell cycle. Mol Biosyst (2009) 0.98
Spatial controls for growth zone formation during the fission yeast cell cycle. Yeast (2008) 0.98
Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer. Horm Mol Biol Clin Investig (2011) 0.97
A simple theoretical framework for understanding heterogeneous differentiation of CD4+ T cells. BMC Syst Biol (2012) 0.97
A hybrid model of mammalian cell cycle regulation. PLoS Comput Biol (2011) 0.95
Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex. FEBS J (2009) 0.93
Cycling without the cyclosome: modeling a yeast strain lacking the APC. Cell Cycle (2004) 0.93
Meiotic prophase requires proteolysis of M phase regulators mediated by the meiosis-specific APC/CAma1. Cell (2012) 0.93
Optimization and model reduction in the high dimensional parameter space of a budding yeast cell cycle model. BMC Syst Biol (2013) 0.93
Systems biologists seek fuller integration of systems biology approaches in new cancer research programs. Cancer Res (2009) 0.92
Molecular mechanisms creating bistable switches at cell cycle transitions. Open Biol (2013) 0.92
Monitoring p53's pulse. Nat Genet (2004) 0.91
Oscillations in Cdc14 release and sequestration reveal a circuit underlying mitotic exit. J Cell Biol (2010) 0.91
Role of the Mad2 dimerization interface in the spindle assembly checkpoint independent of kinetochores. Curr Biol (2012) 0.91
Regulated protein kinases and phosphatases in cell cycle decisions. Curr Opin Cell Biol (2010) 0.91
Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells. FEBS Lett (2013) 0.90
Oscillatory dynamics of cell cycle proteins in single yeast cells analyzed by imaging cytometry. PLoS One (2011) 0.90
The spindle-assembly checkpoint and the beauty of self-destruction. Nat Struct Mol Biol (2012) 0.89
The Eps8/IRSp53/VASP network differentially controls actin capping and bundling in filopodia formation. PLoS Comput Biol (2011) 0.89
Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration. Front Physiol (2012) 0.89
Multisite phosphoregulation of Cdc25 activity refines the mitotic entrance and exit switches. Proc Natl Acad Sci U S A (2012) 0.89
Modeling regulatory networks at Virginia Tech. OMICS (2003) 0.88
System-level feedbacks control cell cycle progression. FEBS Lett (2009) 0.88
Adaptation to the spindle checkpoint is regulated by the interplay between Cdc28/Clbs and PP2ACdc55. J Cell Biol (2013) 0.87
Different effects of redundant feedback loops on a bistable switch. Chaos (2010) 0.87
Rewiring the exit from mitosis. Cell Cycle (2005) 0.86
A kinetic model of the cyclin E/Cdk2 developmental timer in Xenopus laevis embryos. Biophys Chem (2003) 0.86
Hybrid modeling and simulation of stochastic effects on progression through the eukaryotic cell cycle. J Chem Phys (2012) 0.85
Cell cycle control in bacteria and yeast: a case of convergent evolution? Cell Cycle (2006) 0.85
The regulatory network of cell-cycle progression is fundamentally different in plants versus yeast or metazoans. Plant Signal Behav (2010) 0.85
Multistate Model Builder (MSMB): a flexible editor for compact biochemical models. BMC Syst Biol (2014) 0.85
Computational modelling of mitotic exit in budding yeast: the role of separase and Cdc14 endocycles. J R Soc Interface (2011) 0.84
Modeling molecular regulatory networks with JigCell and PET. Methods Mol Biol (2009) 0.83
A mathematical model of mitotic exit in budding yeast: the role of Polo kinase. PLoS One (2012) 0.82
Reverse engineering models of cell cycle regulation. Adv Exp Med Biol (2008) 0.82
Periodic forcing of a mathematical model of the eukaryotic cell cycle. Phys Rev E Stat Nonlin Soft Matter Phys (2006) 0.82
Cell cycle: who turns the crank? Curr Biol (2011) 0.81
Model aggregation: a building-block approach to creating large macromolecular regulatory networks. Bioinformatics (2009) 0.81