Published in Biochem Biophys Res Commun on April 19, 1976
The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener. EMBO J (2001) 7.97
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature (2001) 7.35
A buoyant method for the determination of the superhelix density of closed circular DNA. J Mol Biol (1971) 5.94
Extracellular nucleases of pseudomonas BAL 31. III. Use of the double-strand deoxyriboexonuclease activity as the basis of a convenient method for the mapping of fragments of DNA produced by cleavage with restriction enzymes. Nucleic Acids Res (1978) 5.62
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron (1996) 5.30
Direct fluorescence analysis of genetic polymorphisms by hybridization with oligonucleotide arrays on glass supports. Nucleic Acids Res (1994) 4.77
Extracellular nucleases of Pseudomonas BAL 31. I. Characterization of single strand-specific deoxyriboendonuclease and double-strand deoxyriboexonuclease activities. Nucleic Acids Res (1975) 4.16
Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J Biol Chem (1993) 3.52
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis (2000) 3.46
Extracellular nucleases of Alteromonas espejiana BAL 31.IV. The single strand-specific deoxyriboendonuclease activity as a probe for regions of altered secondary structure in negatively and positively supercoiled closed circular DNA. Nucleic Acids Res (1979) 3.28
HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med (1999) 3.01
Protein folding triggered by electron transfer. Science (1996) 2.99
Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci U S A (1993) 2.79
Cadmium and iron transport by members of a plant metal transporter family in Arabidopsis with homology to Nramp genes. Proc Natl Acad Sci U S A (2000) 2.70
Flexibility of native DNA from the sedimentation behavior as a function of molecular weight and temperature. J Mol Biol (1968) 2.56
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer (2009) 2.39
Sedimentation velocity behavior of closed circular SV40 DNA as a function of superhelix density, ionic strength, counterion and temperature. J Mol Biol (1971) 2.35
The Pendred syndrome gene encodes a chloride-iodide transport protein. Nat Genet (1999) 2.32
Stoichiometry of a recombinant GABAA receptor. J Neurosci (1996) 2.23
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides. Nat Med (1998) 2.20
Quantitative trait loci for refractoriness of Anopheles gambiae to Plasmodium cynomolgi B. Science (1997) 2.08
Electron-tunneling pathways in proteins. Science (1992) 2.08
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiol Dis (2001) 2.07
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation. Proc Natl Acad Sci U S A (1997) 2.03
Kinetic studies of the reduction of ferricytochrome c by Fe(EDTA)2-. J Am Chem Soc (1974) 2.00
Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci (2001) 1.95
A study of a series of recombinant fungal laccases and bilirubin oxidase that exhibit significant differences in redox potential, substrate specificity, and stability. Biochim Biophys Acta (1996) 1.88
Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling. Cancer Res (1999) 1.88
Pathway analysis of protein electron-transfer reactions. Annu Rev Biophys Biomol Struct (1992) 1.87
Cytochrome c folding triggered by electron transfer. Chem Biol (1996) 1.80
Electron tunneling in proteins: coupling through a beta strand. Science (1995) 1.79
Long-range electron transfer in heme proteins. Science (1986) 1.69
Protein ladder sequencing. Science (1993) 1.66
Spectroscopic studies and a structural model for blue copper centers in proteins. Proc Natl Acad Sci U S A (1976) 1.62
A protein from human placental nuclei binds preferentially to 5-methylcytosine-rich DNA. Nature (1984) 1.61
Identification of receptors for neuromedin U and its role in feeding. Nature (2000) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
A sensitive endonuclease probe for lesions in deoxyribonucleic acid helix structure produced by carcinogenic or mutagenic agents. J Biol Chem (1977) 1.59
Dyspepsia and irritable bowel syndrome in China: a population-based endoscopy study of prevalence and impact. Aliment Pharmacol Ther (2010) 1.59
Critical role of c-Kit in beta cell function: increased insulin secretion and protection against diabetes in a mouse model. Diabetologia (2012) 1.58
Transcription factor expression in the developing human fetal endocrine pancreas. Diabetologia (2008) 1.57
A quantitative description of the ground-state wave function of Cu(A) by X-ray absorption spectroscopy: comparison to plastocyanin and relevance to electron transfer. J Am Chem Soc (2001) 1.55
Electron tunneling in single crystals of Pseudomonas aeruginosa azurins. J Am Chem Soc (2001) 1.53
Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities. J Am Chem Soc (2001) 1.53
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nat Neurosci (1999) 1.53
Regulation of Rad51 function by c-Abl in response to DNA damage. J Biol Chem (1998) 1.53
Ligand K-edge X-ray absorption spectroscopy: a direct probe of ligand-metal covalency. Acc Chem Res (2000) 1.50
Biological monitoring of dichloropropene: air concentrations, urinary metabolite, and renal enzyme excretion. Arch Environ Health (1989) 1.50
Effects of buried ionizable amino acids on the reduction potential of recombinant myoglobin. Science (1989) 1.48
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein. Proc Natl Acad Sci U S A (1999) 1.46
Cigarettes and alcohol in relation to colorectal cancer: the Singapore Chinese Health Study. Br J Cancer (2007) 1.46
Sedimentation coefficient of polyoma virus DNA. Biopolymers (1967) 1.46
Interactions between heterologous FtsA and FtsZ proteins at the FtsZ ring. J Bacteriol (1997) 1.45
Cell loss in isolated human islets occurs by apoptosis. Pancreas (2000) 1.45
Fas-mediated cell death promoted by opioids. Nature (1999) 1.45
Generation and regulation of beta-amyloid peptide variants by neurons. J Neurochem (1998) 1.43
The Arabidopsis dual-affinity nitrate transporter gene AtNRT1.1 (CHL1) is activated and functions in nascent organ development during vegetative and reproductive growth. Plant Cell (2001) 1.43
Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites. Biochemistry (1993) 1.42
Suppression of a P450 hydroxylase gene in plant trichome glands enhances natural-product-based aphid resistance. Nat Biotechnol (2001) 1.42
Cell-free assays for gamma-secretase activity. FASEB J (2000) 1.41
Family-based intervention for schizophrenic patients in China. A randomised controlled trial. Br J Psychiatry (1994) 1.41
Preparation and spectroscopic studies of cobalt(II) derivatives of blue copper proteins. Proc Natl Acad Sci U S A (1974) 1.40
Isolation of an ftsZ homolog from the archaebacterium Halobacterium salinarium: implications for the evolution of FtsZ and tubulin. J Bacteriol (1996) 1.40
Olanzapine versus placebo in the treatment of acute mania. Olanzapine HGEH Study Group. Am J Psychiatry (1999) 1.40
Recalculation of the temperature inside capillaries using high buffer concentrations. J Chromatogr A (2001) 1.39
Long-term evaluation of composite sequential bypass for limb-threatening ischemia. J Vasc Surg (1992) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Solution structure of oxidized horse heart cytochrome c. Biochemistry (1997) 1.39
Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiol Dis (1999) 1.38
Properties of photogenerated tryptophan and tyrosyl radicals in structurally characterized proteins containing rhenium(I) tricarbonyl diimines. J Am Chem Soc (2001) 1.37
Quantitative structure-activity relationship analysis of phenolic antioxidants. Free Radic Biol Med (1999) 1.35
PTEN mutations are uncommon in Proteus syndrome. J Med Genet (2001) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers. Vaccine (2000) 1.34
Electron tunneling in protein crystals. Proc Natl Acad Sci U S A (2001) 1.34
Probing the open state of cytochrome P450cam with ruthenium-linker substrates. Proc Natl Acad Sci U S A (2001) 1.33
Identification of the gene (lgtG) encoding the lipooligosaccharide beta chain synthesizing glucosyl transferase from Neisseria gonorrhoeae. Proc Natl Acad Sci U S A (1998) 1.33
Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells. Eur J Immunol (1993) 1.33
Effects of folding on metalloprotein active sites. Proc Natl Acad Sci U S A (1997) 1.33
Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochem Biophys Res Commun (1999) 1.32
Isolation and comparison of two molecular species of the BAL 31 nuclease from Alteromonas espejiana with distinct kinetic properties. J Biol Chem (1983) 1.31
Pathways for electron tunneling in cytochrome c oxidase. J Bioenerg Biomembr (1998) 1.30
Functional differences of the PDS gene product are associated with phenotypic variation in patients with Pendred syndrome and non-syndromic hearing loss (DFNB4). Hum Mol Genet (2000) 1.30
Identification of a tyrosinase epitope recognized by HLA-A24-restricted, tumor-infiltrating lymphocytes. J Immunol (1995) 1.29
Electronic structure of high-spin iron(III)-alkylperoxo complexes and its relation to low-spin analogues: reaction coordinate of O-O bond homolysis. J Am Chem Soc (2001) 1.29
Methylphenidate enhances brain activation and deactivation responses to visual attention and working memory tasks in healthy controls. Neuroimage (2010) 1.28
The currents of life: the terminal electron-transfer complex of respiration. Proc Natl Acad Sci U S A (1995) 1.28
Electron tunneling in azurin: the coupling across a beta-sheet. Chem Biol (1995) 1.27
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Gene expression patterns during intramuscular fat development in cattle. J Anim Sci (2008) 1.27
Low-temperature magnetic circular dichroism studies of native laccase: spectroscopic evidence for exogenous ligand bridging at a trinuclear copper active site. Proc Natl Acad Sci U S A (1985) 1.27
Application of cereals and cereal components in functional foods: a review. Int J Food Microbiol (2002) 1.26
Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily. Biochem Biophys Res Commun (1998) 1.26
Rapid electron injection into multisite metalloproteins: intramolecular electron transfer in cytochrome oxidase. Biophys Chem (1995) 1.24
gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length. J Biol Chem (1999) 1.24