Li-San Wang

Author PubWeight™ 91.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature 2012 13.71
2 Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet 2011 10.07
3 Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 2009 8.09
4 Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet 2010 5.52
5 Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nat Genet 2011 2.97
6 The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila. Nature 2012 2.94
7 Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol 2010 2.91
8 Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA 2013 2.58
9 Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron 2013 2.45
10 Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology 2012 2.08
11 Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae. Nucleic Acids Res 2007 1.98
12 The cobweb of life revealed by genome-scale estimates of horizontal gene transfer. PLoS Biol 2005 1.79
13 Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis. PLoS Genet 2010 1.56
14 Global analysis of RNA secondary structure in two metazoans. Cell Rep 2012 1.50
15 Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Hum Mol Genet 2012 1.46
16 Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential. Nucleic Acids Res 2009 1.44
17 Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms. Arch Neurol 2012 1.42
18 Statistically based postprocessing of phylogenetic analysis by clustering. Bioinformatics 2002 1.41
19 Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study. BMC Neurol 2010 1.32
20 HAMR: high-throughput annotation of modified ribonucleotides. RNA 2013 1.24
21 SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. PLoS One 2013 1.23
22 Design of comprehensive Alzheimer's disease centers to address unmet national needs. Alzheimers Dement 2010 1.14
23 Genomic landscape of a three-generation pedigree segregating affective disorder. PLoS One 2009 1.13
24 Correcting population stratification in genetic association studies using a phylogenetic approach. Bioinformatics 2010 1.08
25 ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathol 2014 1.07
26 A Bayesian approach to efficient differential allocation for resampling-based significance testing. BMC Bioinformatics 2009 1.07
27 Age-correlated gene expression in normal and neurodegenerative human brain tissues. PLoS One 2010 1.06
28 Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease. Neurobiol Aging 2012 1.04
29 PASTA: Ultra-Large Multiple Sequence Alignment for Nucleotide and Amino-Acid Sequences. J Comput Biol 2014 0.99
30 Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia. Blood 2013 0.99
31 DACTAL: divide-and-conquer trees (almost) without alignments. Bioinformatics 2012 0.98
32 Adaptive evolution of chloroplast genome structure inferred using a parametric bootstrap approach. BMC Evol Biol 2006 0.98
33 High-throughput identification of long-range regulatory elements and their target promoters in the human genome. Nucleic Acids Res 2013 0.96
34 Enhanced position weight matrices using mixture models. Bioinformatics 2005 0.94
35 SAVoR: a server for sequencing annotation and visualization of RNA structures. Nucleic Acids Res 2012 0.94
36 CoRAL: predicting non-coding RNAs from small RNA-sequencing data. Nucleic Acids Res 2013 0.88
37 Dense subgraph computation via stochastic search: application to detect transcriptional modules. Bioinformatics 2006 0.86
38 Frequency and clinicopathological characteristics of presenilin 1 Gly206Ala mutation in Puerto Rican Hispanics with dementia. J Alzheimers Dis 2013 0.84
39 Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence. Genes Dev 2013 0.84
40 DRAW+SneakPeek: analysis workflow and quality metric management for DNA-seq experiments. Bioinformatics 2013 0.83
41 Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology. J Neuropathol Exp Neurol 2015 0.83
42 Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases. J Comp Neurol 2013 0.83
43 TREMOR--a tool for retrieving transcriptional modules by incorporating motif covariance. Nucleic Acids Res 2007 0.82
44 Selection of individual VH genes occurs at the pro-B to pre-B cell transition. J Immunol 2011 0.82
45 Computational approaches to the detection and analysis of sequences with intramolecular G-quadruplex forming potential. Methods Mol Biol 2010 0.81
46 Polyploidy, aneuploidy and the evolution of cancer. Adv Exp Med Biol 2010 0.78
47 Evolutionary genomics of host-use in bifurcating demes of RNA virus phi-6. BMC Evol Biol 2012 0.77
48 Analyzing copy number variation using SNP array data: protocols for calling CNV and association tests. Curr Protoc Hum Genet 2013 0.76
49 Analysis of nonlinear gene expression progression reveals extensive pathway and age-specific transitions in aging human brains. PLoS One 2013 0.75
50 FILER: a framework for harmonizing and querying large-scale functional genomics knowledge. NAR Genom Bioinform 2022 0.75