1
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Patterns and rates of exonic de novo mutations in autism spectrum disorders.
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Nature
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2012
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13.71
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2
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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
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Nat Genet
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2011
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10.07
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3
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Enhancing CD8 T-cell memory by modulating fatty acid metabolism.
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Nature
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2009
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8.09
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4
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Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
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Nat Genet
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2010
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5.52
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5
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Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
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Nat Genet
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2011
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2.97
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6
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The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila.
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Nature
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2012
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2.94
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7
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Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
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Arch Neurol
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2010
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2.91
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8
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Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.
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JAMA
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2013
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2.58
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9
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Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders.
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Neuron
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2013
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2.45
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10
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Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
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Neurology
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2012
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2.08
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11
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Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae.
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Nucleic Acids Res
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2007
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1.98
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12
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The cobweb of life revealed by genome-scale estimates of horizontal gene transfer.
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PLoS Biol
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2005
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1.79
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13
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Genome-wide double-stranded RNA sequencing reveals the functional significance of base-paired RNAs in Arabidopsis.
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PLoS Genet
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2010
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1.56
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14
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Global analysis of RNA secondary structure in two metazoans.
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Cell Rep
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2012
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1.50
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15
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Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.
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Hum Mol Genet
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2012
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1.46
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16
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Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.
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Nucleic Acids Res
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2009
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1.44
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17
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Comparison of cerebrospinal fluid levels of tau and Aβ 1-42 in Alzheimer disease and frontotemporal degeneration using 2 analytical platforms.
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Arch Neurol
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2012
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1.42
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18
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Statistically based postprocessing of phylogenetic analysis by clustering.
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Bioinformatics
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2002
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1.41
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19
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Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.
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BMC Neurol
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2010
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1.32
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20
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HAMR: high-throughput annotation of modified ribonucleotides.
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RNA
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2013
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1.24
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21
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SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
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PLoS One
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2013
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1.23
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22
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Design of comprehensive Alzheimer's disease centers to address unmet national needs.
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Alzheimers Dement
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2010
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1.14
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23
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Genomic landscape of a three-generation pedigree segregating affective disorder.
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PLoS One
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2009
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1.13
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24
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Correcting population stratification in genetic association studies using a phylogenetic approach.
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Bioinformatics
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2010
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1.08
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ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
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Acta Neuropathol
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2014
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1.07
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26
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A Bayesian approach to efficient differential allocation for resampling-based significance testing.
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BMC Bioinformatics
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2009
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1.07
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27
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Age-correlated gene expression in normal and neurodegenerative human brain tissues.
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PLoS One
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2010
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1.06
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28
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Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
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Neurobiol Aging
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2012
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1.04
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29
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PASTA: Ultra-Large Multiple Sequence Alignment for Nucleotide and Amino-Acid Sequences.
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J Comput Biol
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2014
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0.99
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Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia.
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Blood
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2013
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0.99
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DACTAL: divide-and-conquer trees (almost) without alignments.
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Bioinformatics
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2012
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0.98
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32
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Adaptive evolution of chloroplast genome structure inferred using a parametric bootstrap approach.
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BMC Evol Biol
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2006
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0.98
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33
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High-throughput identification of long-range regulatory elements and their target promoters in the human genome.
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Nucleic Acids Res
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2013
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0.96
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34
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Enhanced position weight matrices using mixture models.
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Bioinformatics
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2005
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SAVoR: a server for sequencing annotation and visualization of RNA structures.
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Nucleic Acids Res
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2012
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0.94
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CoRAL: predicting non-coding RNAs from small RNA-sequencing data.
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Nucleic Acids Res
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2013
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Dense subgraph computation via stochastic search: application to detect transcriptional modules.
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Bioinformatics
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2006
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Frequency and clinicopathological characteristics of presenilin 1 Gly206Ala mutation in Puerto Rican Hispanics with dementia.
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J Alzheimers Dis
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2013
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Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence.
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Genes Dev
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2013
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0.84
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DRAW+SneakPeek: analysis workflow and quality metric management for DNA-seq experiments.
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Bioinformatics
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2013
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Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.
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J Neuropathol Exp Neurol
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2015
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Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases.
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J Comp Neurol
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2013
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TREMOR--a tool for retrieving transcriptional modules by incorporating motif covariance.
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Nucleic Acids Res
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2007
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Selection of individual VH genes occurs at the pro-B to pre-B cell transition.
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J Immunol
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Computational approaches to the detection and analysis of sequences with intramolecular G-quadruplex forming potential.
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Methods Mol Biol
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2010
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Polyploidy, aneuploidy and the evolution of cancer.
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Adv Exp Med Biol
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2010
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Evolutionary genomics of host-use in bifurcating demes of RNA virus phi-6.
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BMC Evol Biol
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2012
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Analyzing copy number variation using SNP array data: protocols for calling CNV and association tests.
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Curr Protoc Hum Genet
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2013
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Analysis of nonlinear gene expression progression reveals extensive pathway and age-specific transitions in aging human brains.
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PLoS One
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2013
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FILER: a framework for harmonizing and querying large-scale functional genomics knowledge.
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NAR Genom Bioinform
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2022
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