Published in Invest Ophthalmol Vis Sci on November 01, 2007
AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation. Invest Ophthalmol Vis Sci (2008) 1.68
Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm Genome (2011) 1.16
The nucleotide receptor P2RX7 mediates ATP-induced CREB activation in human and murine monocytic cells. J Leukoc Biol (2008) 0.95
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A frameshift mutation in RPGR exon ORF15 causes photoreceptor degeneration and inner retina remodeling in a model of X-linked retinitis pigmentosa. Invest Ophthalmol Vis Sci (2006) 1.51
Disease progression in patients with dominant retinitis pigmentosa and rhodopsin mutations. Invest Ophthalmol Vis Sci (2002) 1.49
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Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death. J Neurosci (2007) 1.33
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Immunolocalization of ciliary neurotrophic factor receptor alpha (CNTFRalpha) in mammalian photoreceptor cells. Mol Vis (2005) 1.14
The dark side of light: rhodopsin and the silent death of vision the proctor lecture. Invest Ophthalmol Vis Sci (2005) 1.11
Expression of ciliary neurotrophic factor activated by retinal Müller cells in eyes with NMDA- and kainic acid-induced neuronal death. Invest Ophthalmol Vis Sci (2000) 1.09
Neurotrophic signaling in normal and degenerating rodent retinas. Exp Eye Res (2001) 1.04
Loss of cone molecular markers in rhodopsin-mutant human retinas with retinitis pigmentosa. Mol Vis (2000) 1.03
Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor. Invest Ophthalmol Vis Sci (2001) 1.03
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The genetic modifier Rpe65Leu(450): effect on light damage susceptibility in c-Fos-deficient mice. Invest Ophthalmol Vis Sci (2003) 0.97
Histopathologic study of variation in severity of retinitis pigmentosa due to the dominant rhodopsin mutation Pro23His. Am J Ophthalmol (2002) 0.94
Gene expression of neurotrophins and their high-affinity Trk receptors in cultured human Müller cells. Ophthalmic Res (2002) 0.93
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Calibration of the retinal illuminance provided by Maxwellian views. Vision Res (1982) 0.92
Neuroprotection in the juvenile rat model of light-induced retinopathy: evidence suggesting a role for FGF-2 and CNTF. Invest Ophthalmol Vis Sci (2007) 0.92
Identification of mouse retinal genes differentially regulated by dim and bright cyclic light rearing. Exp Eye Res (2005) 0.91
The prion protein is neuroprotective against retinal degeneration in vivo. Exp Eye Res (2006) 0.81
Retinal damage in macaque after white light exposures lasting ten minutes to twelve hours. Invest Ophthalmol Vis Sci (1989) 0.79
Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness. Mol Ther (2005) 4.74
An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. Science (2009) 3.29
Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer. Mol Ther (2008) 3.28
Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement. Proc Natl Acad Sci U S A (2013) 2.71
Breed relationships facilitate fine-mapping studies: a 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds. Genome Res (2007) 2.26
Human cone photoreceptor dependence on RPE65 isomerase. Proc Natl Acad Sci U S A (2007) 2.21
Gene therapy rescues cone function in congenital achromatopsia. Hum Mol Genet (2010) 2.18
Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection. Mol Ther (2006) 2.13
Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa. Proc Natl Acad Sci U S A (2012) 2.12
Evaluation of multiple radiographic predictors of cartilage lesions in the hip joints of eight-month-old dogs. Am J Vet Res (2003) 2.09
Different RPGR exon ORF15 mutations in Canids provide insights into photoreceptor cell degeneration. Hum Mol Genet (2002) 2.03
Eye movement recordings as an effectiveness indicator of gene therapy in RPE65-deficient canines: implications for the ocular motor system. Invest Ophthalmol Vis Sci (2006) 2.01
Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa. Invest Ophthalmol Vis Sci (2002) 1.97
Identical mutation in a novel retinal gene causes progressive rod-cone degeneration in dogs and retinitis pigmentosa in humans. Genomics (2006) 1.93
In vivo dynamics of retinal injury and repair in the rhodopsin mutant dog model of human retinitis pigmentosa. Proc Natl Acad Sci U S A (2005) 1.85
A meiotic linkage map of the silver fox, aligned and compared to the canine genome. Genome Res (2007) 1.85
Safety in nonhuman primates of ocular AAV2-RPE65, a candidate treatment for blindness in Leber congenital amaurosis. Hum Gene Ther (2006) 1.81
Canine and human visual cortex intact and responsive despite early retinal blindness from RPE65 mutation. PLoS Med (2007) 1.79
Canine CNGB3 mutations establish cone degeneration as orthologous to the human achromatopsia locus ACHM3. Hum Mol Genet (2002) 1.78
Naturally occurring rhodopsin mutation in the dog causes retinal dysfunction and degeneration mimicking human dominant retinitis pigmentosa. Proc Natl Acad Sci U S A (2002) 1.67
Two putative acetyltransferases, san and deco, are required for establishing sister chromatid cohesion in Drosophila. Curr Biol (2003) 1.66
Bestrophin gene mutations cause canine multifocal retinopathy: a novel animal model for best disease. Invest Ophthalmol Vis Sci (2007) 1.54
A frameshift mutation in RPGR exon ORF15 causes photoreceptor degeneration and inner retina remodeling in a model of X-linked retinitis pigmentosa. Invest Ophthalmol Vis Sci (2006) 1.51
Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs. Proc Natl Acad Sci U S A (2002) 1.50
Linkage disequilibrium mapping in domestic dog breeds narrows the progressive rod-cone degeneration interval and identifies ancestral disease-transmitting chromosome. Genomics (2006) 1.46
Genome-wide association identifies a deletion in the 3' untranslated region of striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy. Hum Genet (2010) 1.43
Correction of clinical manifestations of canine mucopolysaccharidosis I with neonatal retroviral vector gene therapy. Mol Ther (2007) 1.42
Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase. Nat Genet (2003) 1.36
Quantitative trait loci for hip dysplasia in a cross-breed canine pedigree. Mamm Genome (2005) 1.20
A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor. J Biol Chem (2004) 1.19
Canine RD3 mutation establishes rod-cone dysplasia type 2 (rcd2) as ortholog of human and murine rd3. Mamm Genome (2009) 1.16
Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm Genome (2011) 1.16
Immunolocalization of ciliary neurotrophic factor receptor alpha (CNTFRalpha) in mammalian photoreceptor cells. Mol Vis (2005) 1.14
Transient photoreceptor deconstruction by CNTF enhances rAAV-mediated cone functional rescue in late stage CNGB3-achromatopsia. Mol Ther (2013) 1.10
Assessment of canine BEST1 variations identifies new mutations and establishes an independent bestrophinopathy model (cmr3). Mol Vis (2010) 1.05
Differential genetic regulation of canine hip dysplasia and osteoarthritis. PLoS One (2010) 1.03
Analysis of six candidate genes as potential modifiers of disease expression in canine XLPRA1, a model for human X-linked retinitis pigmentosa 3. Mol Vis (2007) 1.02
Linkage mapping of the primary disease locus for collie eye anomaly. Genomics (2003) 1.01
The proto-oncogene C-KIT maps to canid B-chromosomes. Chromosome Res (2005) 1.00
Age-dependent disease expression determines remodeling of the retinal mosaic in carriers of RPGR exon ORF15 mutations. Invest Ophthalmol Vis Sci (2009) 1.00
A digital atlas of the dog brain. PLoS One (2012) 1.00
Exonic SINE insertion in STK38L causes canine early retinal degeneration (erd). Genomics (2010) 1.00
An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9. Mol Vis (2010) 0.99
Altered expression of retinal molecular markers in the canine RPE65 model of Leber congenital amaurosis. Invest Ophthalmol Vis Sci (2010) 0.98
Modeling extent and distribution of zygotic disequilibrium: implications for a multigenerational canine pedigree. Genetics (2006) 0.97
Application of a new subretinal injection device in the dog. Cell Transplant (2006) 0.97
Mapping Loci for fox domestication: deconstruction/reconstruction of a behavioral phenotype. Behav Genet (2010) 0.96
Bone marrow transplantation for feline mucopolysaccharidosis I. Mol Genet Metab (2007) 0.95
Cloning of the canine ABCA4 gene and evaluation in canine cone-rod dystrophies and progressive retinal atrophies. Mol Vis (2004) 0.95
The extent and distribution of linkage disequilibrium in a multi-hierarchic outbred canine pedigree. Mamm Genome (2003) 0.94
Intravitreal injection of ciliary neurotrophic factor (CNTF) causes peripheral remodeling and does not prevent photoreceptor loss in canine RPGR mutant retina. Exp Eye Res (2007) 0.94
Cloning, mapping, and retinal expression of the canine ciliary neurotrophic factor receptor alpha (CNTFRalpha). Invest Ophthalmol Vis Sci (2003) 0.93
Photoreceptor cell death, proliferation and formation of hybrid rod/S-cone photoreceptors in the degenerating STK38L mutant retina. PLoS One (2011) 0.93
A random model for mapping imprinted quantitative trait loci in a structured pedigree: an implication for mapping canine hip dysplasia. Genomics (2007) 0.92
Development and characterization of a normalized canine retinal cDNA library for genomic and expression studies. Invest Ophthalmol Vis Sci (2006) 0.91
Power of a Labrador Retriever-Greyhound pedigree for linkage analysis of hip dysplasia and osteoarthritis. Am J Vet Res (2003) 0.90
Exclusion of RPGRIP1 ins44 from primary causal association with early-onset cone-rod dystrophy in dogs. Invest Ophthalmol Vis Sci (2012) 0.88
Genetics of behavior in the silver fox. Mamm Genome (2011) 0.88
Radiation hybrid mapping of cataract genes in the dog. Mol Vis (2006) 0.88
Molecular consequences of BEST1 gene mutations in canine multifocal retinopathy predict functional implications for human bestrophinopathies. Invest Ophthalmol Vis Sci (2011) 0.88
Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration. BMC Genomics (2014) 0.88
Sequence comparison of prefrontal cortical brain transcriptome from a tame and an aggressive silver fox (Vulpes vulpes). BMC Genomics (2011) 0.87
Transcriptional profile analysis of RPGRORF15 frameshift mutation identifies novel genes associated with retinal degeneration. Invest Ophthalmol Vis Sci (2010) 0.86
Genomic deletion of CNGB3 is identical by descent in multiple canine breeds and causes achromatopsia. BMC Genet (2013) 0.85