Published in Drug Dev Ind Pharm on October 01, 2007
Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model. Lipids Health Dis (2011) 0.79
The effect of two novel cholesterol-lowering agents, disodium ascorbyl phytostanol phosphate (DAPP) and nanostructured aluminosilicate (NSAS) on the expression and activity of P-glycoprotein within Caco-2 cells. Lipids Health Dis (2014) 0.75
LKB1 modulates lung cancer differentiation and metastasis. Nature (2007) 7.80
Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model. Prostate (2010) 1.59
Structural basis of microRNA length variety. Nucleic Acids Res (2010) 1.56
Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases. Pharm Res (2008) 1.54
Myelin water imaging of multiple sclerosis at 7 T: correlations with histopathology. Neuroimage (2008) 1.47
Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future. Pharm Res (2004) 1.47
CAG repeats mimic CUG repeats in the misregulation of alternative splicing. Nucleic Acids Res (2011) 1.42
Ultra deep sequencing detects a low rate of mosaic mutations in tuberous sclerosis complex. Hum Genet (2010) 1.34
Which new approaches to tackling neglected tropical diseases show promise? PLoS Med (2010) 1.34
Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target. Nucleic Acids Res (2011) 1.29
Structures of trinucleotide repeats in human transcripts and their functional implications. Nucleic Acids Res (2003) 1.14
Human enhancer of rudimentary is a molecular partner of PDIP46/SKAR, a protein interacting with DNA polymerase delta and S6K1 and regulating cell growth. FEBS J (2006) 1.11
The role of the precursor structure in the biogenesis of microRNA. Cell Mol Life Sci (2011) 1.11
Cyclosporine A: a review of current oral and intravenous delivery systems. Drug Dev Ind Pharm (2007) 1.11
Development and characterization of oral lipid-based amphotericin B formulations with enhanced drug solubility, stability and antifungal activity in rats infected with Aspergillus fumigatus or Candida albicans. Int J Pharm (2009) 1.10
A prospective assessment of the Y402H variant in complement factor H, genetic variants in C-reactive protein, and risk of age-related macular degeneration. Invest Ophthalmol Vis Sci (2006) 1.09
Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation. J Antimicrob Chemother (2009) 1.07
Effect of acetabular labral tears, repair and resection on hip cartilage strain: A 7T MR study. J Biomech (2009) 1.06
Induction of autophagy is an early response to gefitinib and a potential therapeutic target in breast cancer. PLoS One (2013) 1.04
Lipid formulation strategies for enhancing intestinal transport and absorption of P-glycoprotein (P-gp) substrate drugs: in vitro/in vivo case studies. J Pharm Sci (2007) 1.02
Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake. Adv Drug Deliv Rev (2004) 1.02
Effects of lipid-based oral formulations on plasma and tissue amphotericin B concentrations and renal toxicity in male rats. Antimicrob Agents Chemother (2003) 1.00
Leishmania major abrogates gamma interferon-induced gene expression in human macrophages from a global perspective. Infect Immun (2007) 1.00
Modulation of cancer cell survival pathways using multivalent liposomal therapeutic antibody constructs. Mol Cancer Ther (2007) 1.00
Irinophore C, a novel nanoformulation of irinotecan, alters tumor vascular function and enhances the distribution of 5-fluorouracil and doxorubicin. Clin Cancer Res (2008) 0.99
Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci (2007) 0.99
Ciz1, a p21 cip1/Waf1-interacting zinc finger protein and DNA replication factor, is a novel molecular partner for human enhancer of rudimentary homolog. FEBS J (2007) 0.99
Copy number variation of microRNA genes in the human genome. BMC Genomics (2011) 0.97
Comparison between population average and experimentally measured arterial input function in predicting biopsy results in prostate cancer. Acad Radiol (2010) 0.97
Knockdown of scavenger receptor class B type I reduces prostate specific antigen secretion and viability of prostate cancer cells. Prostate (2011) 0.95
Potential role of acyl-coenzyme A:cholesterol transferase (ACAT) Inhibitors as hypolipidemic and antiatherosclerosis drugs. Pharm Res (2005) 0.94
Postnatal manipulation of Pax6 dosage reverses congenital tissue malformation defects. J Clin Invest (2013) 0.94
Caspase-dependent cleavage of carbamoyl phosphate synthetase II during apoptosis. Mol Pharmacol (2002) 0.93
Device for sectioning prostatectomy specimens to facilitate comparison between histology and in vivo MRI. J Magn Reson Imaging (2010) 0.93
Safety, pharmacokinetics, pharmacodynamics, and plasma lipoprotein distribution of eritoran (E5564) during continuous intravenous infusion into healthy volunteers. Antimicrob Agents Chemother (2004) 0.93
A novel tropically stable oral amphotericin B formulation (iCo-010) exhibits efficacy against visceral Leishmaniasis in a murine model. PLoS Negl Trop Dis (2010) 0.92
Methotrexate loaded poly(L-lactic acid) microspheres for intra-articular delivery of methotrexate to the joint. J Pharm Sci (2004) 0.91
Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice. Metabolism (2003) 0.91
The reformulation of amphotericin B for oral administration to treat systemic fungal infections and visceral leishmaniasis. Expert Opin Drug Deliv (2009) 0.91
Arachidonic acid activation of intratumoral steroid synthesis during prostate cancer progression to castration resistance. Prostate (2010) 0.91
Development of a recombinant Leishmania major strain sensitive to ganciclovir and 5-fluorocytosine for use as a live vaccine challenge in clinical trials. Vaccine (2005) 0.90
CAG and CTG repeat polymorphism in exons of human genes shows distinct features at the expandable loci. Hum Mutat (2007) 0.90
Cholesterol as a potential target for castration-resistant prostate cancer. Pharm Res (2010) 0.90
Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristine. BMC Cancer (2011) 0.90
Pathological basis of diffusely abnormal white matter: insights from magnetic resonance imaging and histology. Mult Scler (2010) 0.89
In vitro human plasma distribution of nanoparticulate paclitaxel is dependent on the physicochemical properties of poly(ethylene glycol)-block-poly(caprolactone) nanoparticles. Eur J Pharm Biopharm (2008) 0.89
A classification of spin frustration in molecular magnets from a physical study of large odd-numbered-metal, odd electron rings. Proc Natl Acad Sci U S A (2012) 0.89
Design and generation of MLPA probe sets for combined copy number and small-mutation analysis of human genes: EGFR as an example. ScientificWorldJournal (2010) 0.89
Haptoglobin inhibits phospholipid transfer protein activity in hyperlipidemic human plasma. Lipids Health Dis (2009) 0.89
HER-2/neu overexpression increases the viable hypoxic cell population within solid tumors without causing changes in tumor vascularization. Mol Cancer Res (2004) 0.89
Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). Prostate (2008) 0.88
Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin. Breast Cancer Res Treat (2007) 0.87
Pharmacokinetics and biodistribution of N-isopropylacrylamide copolymers for the design of pH-sensitive liposomes. Biomaterials (2009) 0.87
Enhancing drug absorption using lipids: a case study presenting the development and pharmacological evaluation of a novel lipid-based oral amphotericin B formulation for the treatment of systemic fungal infections. Adv Drug Deliv Rev (2007) 0.87
A review of the application of lipid-based systems in systemic, dermal/ transdermal, and ocular drug delivery. Crit Rev Ther Drug Carrier Syst (2008) 0.87
Development and evaluation of a dual-modality (MRI/SPECT) molecular imaging bioprobe. Nanomedicine (2011) 0.87
Effects of monoglycerides on P-glycoprotein: modulation of the activity and expression in Caco-2 cell monolayers. Mol Pharm (2008) 0.87
Influence of phytostanol phosphoryl ascorbate, FM-VP4, on pancreatic lipase activity and cholesterol accumulation within Caco-2 cells. J Pharm Pharm Sci (2002) 0.86
Poloxamer 407 (P-407)-mediated reduction in the gene expression of ATP-binding-cassette transporter A1 may contribute to increased cholesterol in peripheral tissues of P-407-treated rats. Eur J Pharmacol (2006) 0.85
Potential mechanisms by which Peceol increases the gastrointestinal absorption of amphotericin B. Drug Dev Ind Pharm (2004) 0.85
Assessing the antifungal activity and toxicity profile of amphotericin B lipid complex (ABLC; Abelcet) in combination with caspofungin in experimental systemic aspergillosis. J Pharm Sci (2004) 0.85
Disodium Ascorbyl Phytostanyl Phosphates (FM-VP4) reduces plasma cholesterol concentration, body weight and abdominal fat gain within a dietary-induced obese mouse model. J Pharm Pharm Sci (2005) 0.85
Lipid excipients Peceol and Gelucire 44/14 decrease P-glycoprotein mediated efflux of rhodamine 123 partially due to modifying P-glycoprotein protein expression within Caco-2 cells. J Pharm Pharm Sci (2007) 0.85
Development of liposomal polyene antibiotics: an historical perspective. J Pharm Pharm Sci (2003) 0.85
Effect of dietary fat on hepatic liver X receptor expression in P-glycoprotein deficient mice: implications for cholesterol metabolism. Lipids Health Dis (2008) 0.85
Extended in vivo pharmacodynamic activity of E5564 in normal volunteers with experimental endotoxemia [corrected]. J Pharmacol Exp Ther (2003) 0.84
Fluorescence of amphotericin B-deoxycholate (fungizone) monomers and aggregates and the effect of heat-treatment. Langmuir (2007) 0.84
Multiparametric MRI maps for detection and grading of dominant prostate tumors. J Magn Reson Imaging (2012) 0.84
Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe. PLoS One (2012) 0.84
Pathological correlates of magnetic resonance imaging texture heterogeneity in multiple sclerosis. Ann Neurol (2013) 0.84
Combined RNAi-mediated suppression of Rictor and EGFR resulted in complete tumor regression in an orthotopic glioblastoma tumor model. PLoS One (2013) 0.84
Inhibition of intestinal absorption of cholesterol by surface-modified nanostructured aluminosilicate compounds. J Pharm Sci (2009) 0.83
Biodistribution and tissue toxicity of amphotericin B in mice following multiple dose administration of a novel oral lipid-based formulation (iCo-009). J Antimicrob Chemother (2010) 0.83
Long circulating lipid nanocapsules for drug detoxification. Biomaterials (2007) 0.83
Cardiometabolic risk factors in experimental spinal cord injury. J Neurotrauma (2010) 0.83
Lipid-based systems for the enhanced delivery of poorly water soluble drugs. Adv Drug Deliv Rev (2007) 0.83
Barriers to treatment for visceral leishmaniasis in hyperendemic areas: India, Bangladesh, Nepal, Brazil and Sudan. Drug Dev Ind Pharm (2010) 0.82
Development and characterization of liposomal disodium ascorbyl phytostanyl phosphates (FM-VP4). Drug Dev Ind Pharm (2004) 0.82
Registration of whole-mount histology and volumetric imaging of the prostate using particle filtering. IEEE Trans Med Imaging (2014) 0.82
Complete Apo AI deficiency in an Iraqi Mandaean family: case studies and review of the literature. J Clin Lipidol (2010) 0.81
Temporal phase correction of multiple echo T2 magnetic resonance images. J Magn Reson (2013) 0.81
Dual physiologically based pharmacokinetic model of liposomal and nonliposomal amphotericin B disposition. Pharm Res (2013) 0.81
Longitudinal studies of angiogenesis in hormone-dependent Shionogi tumors. Neoplasia (2007) 0.81
Review of the quality of pediatric medications in developing countries. J Pharm Sci (2013) 0.81
Tropically stable novel oral lipid formulation of amphotericin B (iCo-010): biodistribution and toxicity in a mouse model. Lipids Health Dis (2011) 0.81
The use of the United States FDA programs as a strategy to advance the development of drug products for neglected tropical diseases. Drug Dev Ind Pharm (2014) 0.81
Tacrolimus-induced elevation in plasma triglyceride concentrations after administration to renal transplant patients is partially due to a decrease in lipoprotein lipase activity and plasma concentrations. Transplantation (2009) 0.81
Efficacy and toxicity of a tropically stable lipid-based formulation of amphotericin B (iCo-010) in a rat model of invasive candidiasis. Int J Pharm (2012) 0.80
Determination of clozapine and its metabolite, norclozapine in various biological matrices using high-performance liquid chromatography. Drug Dev Ind Pharm (2007) 0.80
An MLPA-based strategy for discrete CNV genotyping: CNV-miRNAs as an example. Hum Mutat (2013) 0.80
Impact of the trade-related aspects of intellectual property rights (TRIPS) agreement on India as a supplier of generic antiretrovirals. J Pharm Sci (2010) 0.80
Controlled delivery of BID protein fused with TAT peptide sensitizes cancer cells to apoptosis. BMC Cancer (2014) 0.80
Acute P-407 administration to mice causes hypercholesterolemia by inducing cholesterolgenesis and down-regulating low-density lipoprotein receptor expression. Pharm Res (2006) 0.80
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. Bioorg Med Chem (2010) 0.80
Role of lipid and lipoprotein metabolizing enzymes in the development of atherosclerosis. Indian J Exp Biol (2003) 0.80
Simultaneous determination of a novel antitrypanosomal compound (OSU-36) and its ester derivative (OSU-40) in plasma by HPLC: application to first pharmacokinetic study in rats. J Pharm Pharm Sci (2011) 0.80
Dietary supplementation with phytosterol and ascorbic acid reduces body mass accumulation and alters food transit time in a diet-induced obesity mouse model. Lipids Health Dis (2011) 0.79