Published in Chem Res Toxicol on November 01, 2007
Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model. Cancer Prev Res (Phila) (2011) 1.19
Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras. Biochem Pharmacol (2012) 1.19
Nitric oxide and cancer therapy: the emperor has NO clothes. Curr Pharm Des (2010) 1.05
NOSH-Aspirin: A Novel Nitric Oxide-Hydrogen Sulfide-Releasing Hybrid: A New Class of Anti-inflammatory Pharmaceuticals. ACS Med Chem Lett (2012) 1.03
NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols. J Transl Med (2008) 0.85
Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality. Nitric Oxide (2008) 0.84
A novel aspirin prodrug inhibits NFκB activity and breast cancer stem cell properties. BMC Cancer (2015) 0.79
Comparative methods for analysis of protein covalent modification by electrophilic quinoids formed from xenobiotics. Bioconjug Chem (2009) 0.78
Quinone Methide Bioactivation Pathway: Contribution to Toxicity and/or Cytoprotection? Curr Org Chem (2014) 0.78
Quinone-induced activation of Keap1/Nrf2 signaling by aspirin prodrugs masquerading as nitric oxide. Chem Res Toxicol (2012) 0.78
In vitro evaluation of novel N-acetylalaninate prodrugs that selectively induce apoptosis in prostate cancer cells. BMC Cancer (2014) 0.76
The Antineoplastic Effect of Nitric Oxide-Donating Acetylsalicylic Acid (NO-ASA) in Chronic Lymphocytic Leukemia (CLL) Cells is Highly Dependent on its Positional Isomerism. Ther Adv Hematol (2011) 0.75
Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets β-catenin. Drug Des Devel Ther (2013) 0.75
A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib. Cancer Cell (2012) 2.96
Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion. Nat Med (2013) 2.65
Person-to-person transmission of severe fever with thrombocytopenia syndrome bunyavirus through blood contact. Clin Infect Dis (2011) 2.59
The metabolic syndrome and CVD outcomes for a central Australian cohort. Diabetes Res Clin Pract (2013) 1.97
Trends in blood pressure and body mass index among Chinese children and adolescents from 2005 to 2010. Am J Hypertens (2013) 1.70
Suicide in the Northern Territory, 1981-2002. Med J Aust (2006) 1.68
Prevalence of type 2 diabetes mellitus of Chinese populations in Mainland China, Hong Kong, and Taiwan. Diabetes Res Clin Pract (2006) 1.61
Potential mechanisms of estrogen quinone carcinogenesis. Chem Res Toxicol (2007) 1.56
Characterizing antibody cross-reactivity for immunoaffinity purification of analytes prior to multiplexed liquid chromatography-tandem mass spectrometry. Clin Chem (2012) 1.52
Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis. Blood (2011) 1.52
Prognostic impact and targeting of CRM1 in acute myeloid leukemia. Blood (2013) 1.52
Reduction in natural death and renal failure from a systematic screening and treatment program in an Australian Aboriginal community. Kidney Int Suppl (2003) 1.50
Supramolecular polymerization promoted and controlled through self-sorting. Angew Chem Int Ed Engl (2014) 1.47
Investigating the sustainability of outcomes in a chronic disease treatment programme. Soc Sci Med (2006) 1.46
Secular trends of obesity prevalence in urban Chinese children from 1985 to 2010: gender disparity. PLoS One (2013) 1.43
Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck. Clin Cancer Res (2004) 1.39
Cytochrome p450 compound I. J Am Chem Soc (2006) 1.37
Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance. Blood (2014) 1.29
Lower than expected morbidity and mortality for an Australian Aboriginal population: 10-year follow-up in a decentralised community. Med J Aust (2008) 1.27
Comparison of diabetes management in five countries for general and indigenous populations: an internet-based review. BMC Health Serv Res (2010) 1.26
Comparison of adiponectin, leptin and leptin to adiponectin ratio as diagnostic marker for metabolic syndrome in older adults of Chinese major cities. Diabetes Res Clin Pract (2009) 1.24
Formation of compound I by photo-oxidation of compound II. Org Lett (2005) 1.23
End-stage renal disease in indigenous Australians: a disease of disadvantage. Ethn Dis (2002) 1.22
Delayed referral to a nephrologist: outcomes among patients who survive at least one year on dialysis. Med J Aust (2002) 1.18
Identification of a novel GPR143 deletion in a Chinese family with X-linked congenital nystagmus. Mol Vis (2008) 1.17
Protein arginine methyltransferase 5 is essential for growth of lung cancer cells. Biochem J (2012) 1.15
Specialist outreach to isolated and disadvantaged communities: a population-based study. Lancet (2006) 1.12
Femtomole immunodetection of synthetic and endogenous amyloid-beta oligomers and its application to Alzheimer's disease drug candidate screening. J Mol Neurosci (2003) 1.12
Role of mitochondrial aldehyde dehydrogenase in nitrate tolerance. Mol Pharmacol (2003) 1.12
BCR-ABL gene expression is required for its mutations in a novel KCL-22 cell culture model for acquired resistance of chronic myelogenous leukemia. J Biol Chem (2009) 1.11
Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway. J Biol Chem (2008) 1.09
Highly reactive electrophilic oxidants in cytochrome P450 catalysis. Biochem Biophys Res Commun (2005) 1.08
Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens. Chem Res Toxicol (2010) 1.07
Models and tests of optimal density and maximal yield for crop plants. Proc Natl Acad Sci U S A (2012) 1.06
Prognostic significance of nemo-like kinase (NLK) expression in patients with gallbladder cancer. Tumour Biol (2013) 1.05
Renal transplantation for Indigenous Australians: identifying the barriers to equitable access. Ethn Health (2003) 1.05
Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Res (2011) 1.05
Insights into plant size-density relationships from models and agricultural crops. Proc Natl Acad Sci U S A (2012) 1.04
Polyelectrolyte multilayer as matrix for electrochemical deposition of gold clusters: toward super-hydrophobic surface. J Am Chem Soc (2004) 1.04
Bioactivation of the selective estrogen receptor modulator desmethylated arzoxifene to quinoids: 4'-fluoro substitution prevents quinoid formation. Chem Res Toxicol (2005) 1.04
Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones. Chem Res Toxicol (2004) 1.04
Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment. Blood (2013) 1.03
Exploring the redox reactions between heme and tetrahydrobiopterin in the nitric oxide synthases. Dalton Trans (2005) 1.03
Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design. J Mol Biol (2007) 1.01
Clinical characteristics and endoscopic treatment with cyanoacrylate injection in patients with duodenal varices. Scand J Gastroenterol (2009) 1.01
Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus. J Biol Chem (2009) 0.99
Dual redox responsive assemblies formed from diselenide block copolymers. J Am Chem Soc (2010) 0.99
Identification of an Atlantic salmon IFN multigene cluster encoding three IFN subtypes with very different expression properties. Dev Comp Immunol (2008) 0.98
Analysis of protein covalent modification by xenobiotics using a covert oxidatively activated tag: raloxifene proof-of-principle study. Chem Res Toxicol (2005) 0.98
Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Res (2012) 0.97
An enzyme-responsive polymeric superamphiphile. Angew Chem Int Ed Engl (2010) 0.96
Autologous transplantation of retinal pigment epithelium-Bruch's membrane complex for hemorrhagic age-related macular degeneration. Invest Ophthalmol Vis Sci (2008) 0.96
A randomized double blind, placebo controlled trial of topical Tripterygium wilfordii in rheumatoid arthritis: reanalysis using logistic regression analysis. J Rheumatol (2003) 0.96
Anthropometric measurements of Australian Aboriginal adults living in remote areas: comparison with nationally representative findings. Am J Hum Biol (2008) 0.96
Quinoids formed from estrogens and antiestrogens. Methods Enzymol (2004) 0.96
Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation. Chem Res Toxicol (2010) 0.95
Disorders of glucose regulation in adults and birth weight: results from the Australian Diabetes, Obesity and Lifestyle (AUSDIAB) Study. Diabetes Care (2007) 0.94
Treatment of coracoid process fractures associated with acromioclavicular dislocation using clavicular hook plate and coracoid screws. J Shoulder Elbow Surg (2009) 0.94
Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo. Mol Cancer Ther (2007) 0.94
Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors. ACS Chem Biol (2010) 0.94
Supramolecular Polymers: Historical Development, Preparation, Characterization, and Functions. Chem Rev (2015) 0.93
25th anniversary article: reversible and adaptive functional supramolecular materials: "noncovalent interaction" matters. Adv Mater (2013) 0.93
Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity. J Med Chem (2007) 0.92
BMI percentile curves for Chinese children aged 7-18 years, in comparison with the WHO and the US Centers for Disease Control and Prevention references. Public Health Nutr (2010) 0.92
Quantifying the excess risk for proteinuria, hypertension and diabetes in Australian Aborigines: comparison of profiles in three remote communities in the Northern Territory with those in the AusDiab study. Aust N Z J Public Health (2007) 0.92
Randomized, double-blind, crossover study of palonosetron compared with granisetron for the prevention of chemotherapy-induced nausea and vomiting in a Chinese population. Med Oncol (2010) 0.91
Water-soluble supramolecular polymerization driven by multiple host-stabilized charge-transfer interactions. Angew Chem Int Ed Engl (2010) 0.91
[Transesophageal intraluminal ultrasonography in diagnosis and differential diagnosis of esophageal leiomyoma]. Zhonghua Yi Xue Za Zhi (2002) 0.91
Photocontrolled reversible supramolecular assemblies of an azobenzene-containing surfactant with alpha-cyclodextrin. Angew Chem Int Ed Engl (2007) 0.91
Ginsenoside Rg1 protection against β-amyloid peptide-induced neuronal apoptosis via estrogen receptor α and glucocorticoid receptor-dependent anti-protein nitration pathway. Neuropharmacology (2012) 0.91
Is S-nitrosocysteine a true surrogate for nitric oxide? Antioxid Redox Signal (2012) 0.91
Re-expression of microRNA-150 induces EBV-positive Burkitt lymphoma differentiation by modulating c-Myb in vitro. Cancer Sci (2013) 0.91
Exploring the pathways leading from disadvantage to end-stage renal disease for indigenous Australians. Soc Sci Med (2004) 0.91
Bioactivation of Selective Estrogen Receptor Modulators (SERMs). Chem Res Toxicol (2006) 0.90
Anthropometric indices and their relationship with diabetes, hypertension and dyslipidemia in Australian Aboriginal people and Torres Strait Islanders. Eur J Cardiovasc Prev Rehabil (2007) 0.90
Increasing incidence of type 1 diabetes in children aged 0-14 years in Harbin, China (1990-2000). Prim Care Diabetes (2008) 0.90
Association between obesity and atopic disorders in Chinese adults: an individually matched case-control study. BMC Public Health (2013) 0.90
Per-6-substituted-per-6-deoxy beta-cyclodextrins inhibit the formation of beta-amyloid peptide derived soluble oligomers. J Med Chem (2004) 0.90
Severe and differential underestimation of self-reported smoking prevalence in Chinese adolescents. Int J Behav Med (2014) 0.89
Benzothiophene Selective Estrogen Receptor Modulators Provide Neuroprotection by a novel GPR30-dependent Mechanism. ACS Chem Neurosci (2011) 0.89
Urban disadvantage and delayed nephrology referral in Australia. Health Place (2003) 0.89
Importance of native language in a population-based health survey among ethnic Chinese in Australia. Aust N Z J Public Health (2008) 0.89
Photocontrolled self-assembly and disassembly of block ionomer complex vesicles: a facile approach toward supramolecular polymer nanocontainers. Langmuir (2010) 0.88
Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms. Mol Cancer Ther (2007) 0.88
Cognitive deficits in rats after forebrain cholinergic depletion are reversed by a novel NO mimetic nitrate ester. Neuropsychopharmacology (2006) 0.88
Chemical modification modulates estrogenic activity, oxidative reactivity, and metabolic stability in 4'F-DMA, a new benzothiophene selective estrogen receptor modulator. Chem Res Toxicol (2006) 0.88
Exploring clinical predictors of cardiovascular disease in a central Australian Aboriginal cohort. Eur J Prev Cardiol (2012) 0.87
2-Methoxyestradiol and analogs as novel antiproliferative agents: analysis of three-dimensional quantitative structure-activity relationships for DNA synthesis inhibition and estrogen receptor binding. Mol Pharmacol (2002) 0.87
Bioactivation of the selective estrogen receptor modulator acolbifene to quinone methides. Chem Res Toxicol (2005) 0.87
Activation of estrogen receptor-mediated gene transcription by the equine estrogen metabolite, 4-methoxyequilenin, in human breast cancer cells. Endocrinology (2007) 0.87
Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations. J Am Chem Soc (2003) 0.87
Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene. ChemMedChem (2007) 0.87
Problematic detoxification of estrogen quinones by NAD(P)H-dependent quinone oxidoreductase and glutathione-S-transferase. Chem Res Toxicol (2008) 0.87
Renal disease, the metabolic syndrome, and cardiovascular disease. Ethn Dis (2006) 0.86